Abbott Initiates U.S. Study of Absolute Pro(TM) Peripheral Stent System for Iliac Artery Disease

...n symptom of PAD is claudication, a sharp, cramp-like pain in the legs that occurs when walking or exercising. For patients with iliac artery disease, claudication occurs most frequently in the thigh or hips. PAD most commonly affects people age 40 and older,* and can lead to reduced walking capacity, chronic pai...

Walking Program May Relieve Peripheral Artery Pain

... of participants ended up needing vascular surgery for their condition. "Supervised exercise therapy represents a viable treatment of intermittent claudication with no known complications, which cannot be said of invasive treatment options," lead author Dr. Joep A. W. Teijink, a vascular surgeon at Atrium Med...

Exercise improves leg pain caused by arterial disease

...he February issue of Radiology . Intermittent claudication is a painful leg condition affecting some patients...fter six and 12 months, patients with intermittent claudication benefited equally from either revascularization or..." For the study, 151 patients with intermittent claudication were randomly assigned to undergo revascularizatio...

Pioneer(R) Surgical Technology Introduces the BacJac(TM) Interspinous Decompression System to the European Spine Market

...g the International SpineWeek meeting in Geneva, Switzerland. The BacJac system is designed to relieve pain in patients with Neurogenic Intermittent claudication (NIC) due to Lumbar Spinal Stenosis (LSS). The BacJac achieves spinal decompression by limiting the symptomatic extension while maintaining physiologi...

Common Drug Eases Leg Pain From Walking

...pain after making lifestyle modifications," De Backer said. More information The American Academy of Family Physicians has more about PAD and claudication . -- Robert Preidt SOURCE: Center for the Advancement of Health, news release, May 2008 ...

JCI online early table of contents: Jan. 2, 2008

...is a disease of the limbs caused by obstruction of the blood vessels. Moderate PVD causes pain when walking, which is known clinically as intermittent claudication (IC); while patients with severe disease have decreased blood and oxygen flow in the limbs (critical limb ischemia [CLI]) that can result in tissue in...

Diffusion Pharmaceuticals Announces Results of Phase I Human Trial of Lead Drug Candidate, Trans Sodium Crocetinate (TSC) and Completion of a $4.5 Million Private Placement

...umors as soon as possible." In addition, the company is planning a clinical trial in peripheral vascular disease patients suffering from intermittent claudication (i.e., intense leg pain while walking) to evaluate the effect of TSC on tissue oxygenation in these patients using a standardized treadmill test. Site...

REACH Registry Highlights That Patients With Peripheral Arterial Disease (PAD) Suffer High Rates of Heart Attack, Stroke, Hospitalization, and Death

...reimbursed, especially in Europe." Details on Hirsch Analysis Results: REACH enrolled 8581 individuals with PAD, by asymptomatic ABI<0.9 alone (8%); claudication (65%); prior limb revascularization (50%); or amputation (13%). Risk factors were prevalent (diabetes 44%, current smoking 24%, hypercholesterolemia 6...

A herbal delight for athletes in solving cramp and pain problems

...r of the smallest veins commonly associated with diabetes), or intermittent claudication (a blood vessel disease that causes the legs to easily cramp).This study al...croangiopathy had a 20.8 percent reduction in pain, while participants with claudication experienced a 21 percent decrease in the amount of pain experienced while s...

Simple Arm Exercises Could Help Relieving Leg Pain

...narrow that it cannot deliver enough oxygen-containing blood to the legs during walking exercise. This results in leg pain known as intermittent claudication and forces the person to stop and rest until it passes. Smoking, diabetes, high blood pressure and a poor diet are high risk factors in this disease. ...

Claudication in Medical Technology

Diffusion Pharmaceuticals Announces Initiation of a Phase I/II Clinical Trial in Patients with Peripheral Arterial Disease (PAD)

...l endpoints of the study are peak walking time and claudication onset time, as demonstrated by exercise treadmill ...as reliable indicators of efficacy in intermittent claudication clinical trials. Safety and pharmacokinetic assess...ionship and effect of TSC on peak walking time and claudication onset time in intermittent...

Rifalazil Trial (PROVIDENCE-1) Fails to Provide Significant Clinical Benefit in Patients With Peripheral Arterial Disease

... those given rifalazil against those given a placebo. The study enrolled 297 consenting men and women (40-80 years old) with diagnosis of intermittent claudication due to PAD who also had high levels of antibodies to C. pneumoniae. Researchers used treadmills and quality of life questionnaires to chart patients' ...

ActivBiotics to Present Results of Pivotal Study in the Treatment of Peripheral Arterial Disease at AHA Meeting

... of the trial's Steering Committee, will be presenting. PROVIDENCE-1 (Prospective Evaluation of Rifalazil Effect on Vascular Symptoms of Intermittent claudication and Other Endpoints in Chlamydia Seropositive Patients) is the first of two planned Phase III clinical trials to study the ability of rifalazil to imp...

Claudication in Medical Definition

Pathology

...rioles and capillaries Atherosclerosis - Aortic dissection - Raynaud's phenomenon / Raynaud's disease - Buerger's disease - Intermittent claudication Veins , lymphatic vessels and lymph nodes Thrombosis - Phlebitis - Deep vein thrombosis - Portal vein thrombosis - Venous throm...

Claudication in Medical Dictionary

Claudication

Claudication , literally 'limping' (Latin), is used as a medical term to indicate impairment in walking. It is also used figuratively. Read about claudication , cramping in the lower leg while walking or exercising ... Who typically is affected by claudication ? What is the progno...

Intermittent claudication

Intermittent claudication is a clinical diagnosis given for muscle pain, classically calf muscle, which occurs during exercise and is relieved by a short period of rest. INTERMITTENT CLAUDICATION & PERIPHERAL VASCULAR DISEASE. What is peripheral vascular disease(PVD) ... H...

Hardening Of The Arteries

...arterectomy (removal of plaque from the carotid arteries ) may be needed ... Hardening of the Arteries . Peripheral Vascular Disease or claudication ... cholesterol build up in the walls of the arteries leading to the legs and/or feet. ... (pronounced "ath-a-ro-skla-RAH-tic") disease, ...

Arterial insufficiency

...erial wound somewhat dry, as they have found ... Chronic arterial insufficiency of the lower extremity is usually due to atherosclerosis. ... claudication is the least serious form of arterial insufficiency . ... Leg ulcers. Authoritative facts about the skin from the New Zealand Dermatological ...

Claudication in Biological News

Natural pine bark extract relieves muscle cramp and pain in athletes and diabetics

...r of the smallest veins commonly associated with diabetes), or intermittent claudication (a blood vessel disease that causes the legs to easily cramp).This study al...croangiopathy had a 20.8 percent reduction in pain, while participants with claudication experienced a 21 percent decrease in the amount of pain experienced while s...

Claudication in Biological Technology

Results From Phase 2 Clinical Study of 6R-BH4 in Peripheral Arterial Disease Not Statistically Significant

...nificant difference between 6R-BH4 and placebo, and the secondary endpoint, claudication onset time, also did not show a difference. Addition of Vitamin C to 6R-BH...4. The secondary objective of the study was to evaluate the mean change in claudication onset time from baseline to week 24. About 6R-BH4 6R-BH4, commonly...

Co-Inventor of Amgen's Aranesp(R) Technology Directs Worldwide Patent Strategy for Diffusion Pharmaceuticals' First-in-Class Oxygen Enhancing Therapeutics

...gher than the estimated efficacious human dose. Clinical trials will begin in 2008 in peripheral vascular disease patients suffering from intermittent claudication and in cancer patients undergoing radiation therapy. Diffusion Pharmaceuticals, which is privately held, is located in Charlottesville, Virginia. For ...