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Circulating in Medical News

Bone from blood: Circulating cells form bone outside the normal skeleton, Penn study finds

PHILADELPHIA The accepted dogma has been that bone-forming cells, derived from the body's connective tissue, are the only cells able to form the skeleton. However, new research shows that specialized cells in the blood share a common origin with white blood cells derived from the bone marrow and t...

Levels of Circulating Tumor Cells Could Predict Prostate Cancer Outcome

New method of tracking changes proves better predictor than PSA, study says WEDNESDAY, Feb. 11 (HealthDay News) -- Checking for changes in the number of circulating tumor cells (CTCs) could help doctors predict advanced prostate cancer patients' survival and response to treatment, U.S....

High circulating D-dimers are associated with presence of ascites

The liver is the production site of most of the proteins which favour and inhibit the process of coagulation and fibrinolysis. Patients with liver cirrhosis may develop serious coagulopathy and a hyperfibrinolytic state, which contributes to the bleeding tendency. Plasma levels of fragment D-dimer...

FDA Clears Cellsearch(TM) Circulating Tumor Cell Test for Monitoring Metastatic Prostate Cancer Patients

Advanced technology capable of detecting minute numbers of circulating cancer cells in a blood sample; the CellSearch(TM) test can help guide patient care decisions RARITAN, N.J., Feb. 27 /PRNewswire/ -- Veridex, LLC today announced that the U.S. Food and Drug Administration (FDA) has gran...

Rapid Swine Flu Test Misses Many Infections

... negative but actually have the flu, Shaw said, "we want to emphasis that the clinician should also go by the patient's symptoms and what they know is circulating in the community." Positive test results are accurate, however. "But a positive result only tells you it's flu, not what kind," Shaw said. "It cou...

Bellicum Pharmaceuticals Announces Initiation of Phase I/II Clinical Trial of Novel Vaccine for Patients With Advanced Prostate Cancer

...gible to receive booster vaccinations every eight weeks for up to one year. Exploratory efficacy endpoints include prostate-specific antigen dynamics, circulating tumor cell count, antigen-specific immune response, and clinical response. Additional information can be found at www.clinicaltrials.gov. Belli...
Circulating in Medical Technology

Journal of Clinical Oncology Article Highlights CellSearch(TM) Circulating Tumor Cell Test in Treatment of Metastatic Colorectal Cancer

Data Support Prognostic Value of Circulating Tumor Cells RARITAN, N.J., July 25 /PRNewswire/ -- An international, prospective clinical trial found the number of circulating tumor cells (CTCs) is a strong indicator of progression-free and overall survival among metastatic colorectal cancer pa...

Biocept Announces Study to Isolate Circulating Tumor Cells from Blood

SAN DIEGO, Dec. 3 /PRNewswire/ -- Biocept, an emerging leader in biotechnology, is initiating a collaborative study with the University of Texas M.D. Anderson Cancer Center to investigate the ability to isolate circulating tumor cells (CTCs) in blood. The study will use Biocept's proprietary C...

New Data Published in The Lancet Show GSK's ROTARIX(R) Offers Protection Against the Most Common Circulating Rotavirus Types

Protection Sustained During the First Two Years of Life PHILADELPHIA, Nov. 23 /PRNewswire-FirstCall/ -- New data from a large European clinical trial published today in The Lancet show ROTARIX(R), GlaxoSmithKline's (NYSE: GSK ) oral rotavirus candidate vaccine to prevent rotavirus gas...

Isis Reports Strong Financial Results and Highlights for Second Quarter of 2009

...ated with docetaxel alone. OncoGenex reported that OGX-427 was well tolerated as a monotherapy in a Phase 1 study and demonstrated declines in circulating tumor cells and evidence of reduction in tumor markers. Eli Lilly and Company recently completed its Phase 1 study of LY2181308 and presented ...

Video: FDA Approves INVEGA(R) SUSTENNA(TM) for the Acute and Maintenance Treatment of Schizophrenia

...ecomes used to the medicine. INVEGA((R)) SUSTENNA(TM) and similar medicines have been associated with decreases in the counts of white cells in circulating blood. If you have a history of low white blood cell counts or have unexplained fever or infection, then please contact your doctor right away. ...

Octapharma Accepting Applications for Research Grants on Immunotherapy, Coagulation Disorders and Critical Care

...[human] 5%), is used to treat disorders of the immune system, and Octapharma's Albumin (Human) is indicated for the restoration and maintenance of circulating blood volume. Based in Lachen, Switzerland, Octapharma employs over 3,000 people and has biopharmaceutical experience in 80 countries worldwide, inclu...
Circulating in Medical Products

OKT3, Circulating Drug Level

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Nonspecific Circulating Anticoagulant Inhibitor PTT

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Nonspecific Circulating Anticoagulant Inhibitor PT

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

CIC (C1-q) EIA Auto-Immune Markers 001-EK-CIC Circulating Immune Complexes

Description: Circulating Immune Complexes from patient serum or plasma, standards and controls are incubated with human C1q absorbed onto microtiter wells. After a washing step, an alkaline phosphatase labeled conjugate is added, which binds to the Fc region of human IgG. After another washing step, the enzym...
Company:ALPCO Diagnostics

BinaxNOW Malaria (5 Tests)

Description:... For the qualitative differential detection of circulating Plasmodium falciparum (P.f) antigen and an antigen that is common to all four species of malaria:plasmodium falciparum (P.f), plasmodium vivax (P.v), ...
Company:Inverness Medical Professional Diagnostics

BinaxNOW Malaria (25 Tests)

Description:... For the qualitative differential detection of circulating Plasmodium falciparum (P.f) antigen and an antigen that is common to all four species of malaria:plasmodium falciparum (P.f), plasmodium vivax (P.v), ...
Company:Inverness Medical Professional Diagnostics
Circulating in Medical Dictionary

Thyrotoxicosis

...cosis which is not due to the administration of thyroid hormone. ... he term thyrotoxicosis refers to all causes of ele- vated thyroid hormones circulating in the ... The most common cause of thyrotoxicosis is Graves' ... Causes of thyrotoxicosis include those evident in the general population, as...

Testosterone

..... Testosterone is the principal androgen in men and is required for normal sperm production. ... In males, the testes produce most of the circulating testosterone . ... Testosterone levels are used to assess: Early or late puberty in boys ... A testosterone blood test may be done if a b...

Thrombocytopenia

... count. ... Thrombocytopenia Symptoms, Treatments and Medications ... Thrombocytopenia is a condition in which there is a deficient number of circulating platelets. ... INTRODUCTION Immune thrombocytopenic purpura (idiopathic thrombocytopenic ... Approach to the adult patient with thrombocytopeni...

Serum iron

... Serum iron is a medical laboratory test that measures the amount of circulating iron that is bound to transferrin. Clinicians order this laboratory test when they are concerned about iron deficiency, which can cause anemia a...

SARS

...nts ... One of the most alarming features of SARS in these areas is its rapid spread in ... Oregon ACD: SARS home page ... SARS is no longer circulating among humans. ... After 2 to 7 days, SARS patients may develop a dry cough and have trouble breathing. ... In April 2003 there was an outbreak...

Renin

... Renin , also known as Angiotensinogenase, is a circulating enzyme that participates in the body's renin -angiotensin system (RAS) that mediates extracellular volume, and arterial vasoconstriction. Thus ...
Circulating in Biological News

Looking through the eyes of a mouse, scientists monitor circulating cells in its bloodstream

WASHINGTON, Dec. 3 A team of researchers from the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) have developed an optical device that allows them to peer through the eyes of a mouse and monitor the cells passing through its bloodstream. ...

Hap1 protein links circulating insulin to brain circuits that regulate feeding behavior in mice

Researchers have discovered how the protein Hap1, which is abundant in the brain's hypothalamus, serves as the link between circulating insulin in the blood and the neural circuitry that controls feeding behavior in mice. Illumination of the neural pathway used by hormones to regulate appetite an...

Research casts doubt on circulating stem cells

Adult stem cells taken from bone marrow are the "shooting stars" of their field. Many research scientists have been speculating that the cells might be able to pass through the blood into diseased organs and replace defective tissue. Such cells are seen as the potential key to the treatment of cert...

Spallation Neutron Source sees first target replacement

...ar accelerator strikes the target 60 times per second with a force comparable to bursts from a large-caliber machine gun, "spalling" neutrons from the circulating mercury inside. Eventually, the wear and tear of those forces were expected over time to damage the stainless steel of the target and render it unu...

New lab test offers better prediction of HIV microbicide safety

...ing an impermeable barrier to HIV. If a microbicide disrupts the barrier's structural integrity, HIV would be able to slip through the gaps and infect circulating T cells. To test this theory, Pedro Mesquita, a postdoctoral fellow in Dr. Herold's lab, developed a model that mimicked the genital tract environm...

Data published in the New England Journal of Medicine support use of raxibacumab (ABthrax) for the treatment of inhalation anthrax

... bacteria into the blood and tissues. In an inhalation anthrax attack, people may not know they are infected with anthrax until the toxins already are circulating in their blood, and it may be too late for antibiotics alone to be effective. "We are very proud that the importance of these data and the rigor a...
Circulating in Biological Technology

Monitoring Circulating Tumor Cells With the CellSearch(R) System Can Predict Prognosis in Metastatic Breast Cancer

RARITAN, N.J., July 13 /PRNewswire/ -- Measuring the change in circulating tumor cell (CTC) count can accurately predict the prognosis and survival in patients with metastatic breast cancer (MBC), according to a newly published report in the July 10 issue of the Journal of Clinical Oncol...

OncoGenex Pharmaceuticals Announces OGX-427 Treatment Demonstrates Safety, Evidence of Declines in Circulating Tumor Cells and Reductions in Tumor Markers in a Phase 1 Cancer Trial

BOTHELL, WA, and VANCOUVER, May 30 /PRNewswire-FirstCall/ - OncoGenex Pharmaceuticals, Inc. (NASDAQ: OGXI ) today announced preliminary results of a Phase 1 trial presented during an oral presentation at the American Society of Clinical Oncology (ASCO) Annual Meeting. Preliminary results as of A...

Cleveland Clinic Recognizes Circulating Tumor Cell Technology as Top Medical Innovation for 2009

RARITAN, N.J., Nov. 12 /PRNewswire/ -- Veridex, LLC announced today that the technology used in the CellSearch(R) System to measure circulating tumor cells (CTCs) was ranked as the top medical innovation for 2009 by the Cleveland Clinic, a leading multispecialty academic medical center. The ra...

SEQUENOM Reports Second Quarter 2009 Financial Results and Highlights

...o of prenatal test methods by combining the versatility of the MassARRAY system with the company's SEQureDx technology, which enables the detection of circulating cell-free fetal nucleic acids in a maternal blood sample. The company is also developing tests for oncology, infectious diseases and other disorders. ...

OncoGenex Reports Second Quarter 2009 Financial Results

...ated as a monotherapy. In addition, OGX-427 demonstrated declines in circulating tumor cells at all doses evaluated as well as evidence of reduction in tumor markers. Reductions in circulating tumor cells and tumor markers both suggest single-agent activity war...

Medicago's H1N1 pandemic vaccine candidate shows positive response in 100% of vaccinated animals after a single dose

... challenge of current pandemic influenza vaccines is they have to match the circulating strain in order to be effective. "We have already demonstrated the speed ...fluenza vaccines are also capable of providing protection against different circulating viral strains," said Andy Sheldon, President and CEO of Medicago. "Unlike c...
Circulating in Biological Products

Mouse Anti-Nop1p / Fibrillarin Monoclonal Antibody, Unconjugated, Clone A00104.01 from GenScript Corporation

Description:...been determined and shown to consist of 2 extended b-sheets flanked by 4 a-helixes. Patients with the autoimmune disease scleroderma often have strong circulating autoantibodies to a 34kDa protein which was subsequently found to be fibrillarin. Fibrillarin is an excellent marker for the nucleolus. Antigen: R...
Company:GenScript Corporation

Porcine Leptin ELISA Kit from Diagnostic Systems Laboratories, Inc.

Description:... different leptin production rates. The nature of circulating leptin has not been fully explored but the suggestion that it is bound to a circulating protein has been presented. Whether this is a separate protein or represents a circulating form of the leptin receptor remains to be investig...
Company:Diagnostic Systems Laboratories, Inc.

Free Activin B ELISA Kit from Diagnostic Systems Laboratories, Inc.

Description:...e regulatory role, while both inhibins and activins are found to bind reversibly with a2-macroglobulin (3). Despite numerous studies investigating the circulating levels of the various activin molecules in numerous disease states, no clear physiological roles have been established other than the stimulatory acti...
Company:Diagnostic Systems Laboratories, Inc.

Free Activin AB ELISA Kit from Diagnostic Systems Laboratories, Inc.

Description:...e regulatory role, while both inhibins and activins are found to bind reversibly with a2-macroglobulin (3). Despite numerous studies investigating the circulating levels of the various activin molecules in numerous disease states, no clear physiological roles have been established other than the stimulatory acti...
Company:Diagnostic Systems Laboratories, Inc.

Free Activin A ELISA Kit from Diagnostic Systems Laboratories, Inc.

Description:...e regulatory role, while both inhibins and activins are found to bind reversibly with a2-macroglobulin (3). Despite numerous studies investigating the circulating levels of the various activin molecules in numerous disease states, no clear physiological roles have been established other than the stimulatory acti...
Company:Diagnostic Systems Laboratories, Inc.
Circulating in Biological Definition

Alcohol

...ning of alkuhul would have been first extended to distilled substances in general, and then narrowed to ethanol. This conjectured etymology has been circulating in England since 1672 at least ( OED ). However, this derivation is suspicious since the current Arabic name for alcohol, الك&#...

B cell

...type has a unique receptor protein on its membrane that will bind to one particular antigen; at any one time in the human body millions of B cells are circulating in the blood and lymph, but are not producing antibodies. There are two types of B cells: Plasma B cells secrete antibodies which effect t...

Blood

... Red blood cells (erythrocytes) are present in the blood and help carry oxygen to the rest of the cells in the body Blood is a circulating tissue composed of fluid plasma and cells ( red blood cells , white blood cells , platelets ). Medical terms related to blood often begin in ...

Immune system

...locytes ( polymorphonuclear leukocytes , PMN) that can engulf ( phagocytose ) foreign substances. Macrophages are thought to mature continuously from circulating monocytes. Phagocytosis involves chemotaxis , where phagocytic cells are attracted to microorganisms by means of chemotactic chemicals like microbi...

Immunology

...ular in nature and not associated with any specific organ, but imbedded or circulating in various tissues located about the body. Classical immunology Cl... be seen from simple phagocytotic protection of single celled organisms, to circulating antimicrobial peptides in insects to lymphoid organs in vertebrates. Of cou...

Insulin

...and elsewhere increased amino acid uptake – forces cells to absorb circulating amino acids; lack of insulin inhibits absorption increased potassium upt...re, indirectly, under insulin control in certain body cell types. A lack of circulating insulin will prevent glucose from entering those cells (eg, in untreated Ty...
Circulating in Biological Dictionary

Vessels

... through which the blood ... capillaries, all vessels also contain ... Blood vessels , then, are hollow utensils for carrying blood. ... Besides circulating blood, the blood vessels provide two important means of ... Shop for Vessels at Target.com - Free Shipping on 150,000+ Products. ... GLASS VES...

Venules

... venous swellings characterized by simple cuboidal cells as opposed to simple Squamous cells found in regular venules . HEVs enable lymphocytes circulating in the blood to directly enter a lymph node . The blood vessels consist of arteries, arterioles, capillaries, venules , and veins. ... the cap...

Transferrin receptor

...ferrin Receptor ) Purified Low Endotoxin Functional ... Transferrin receptor was identified in serum (6) after investigators recognized ... circulating transferrin receptor is a truncated form of tissue receptor (10) ... ... with human), anti-TFRC, Transferrin receptor protein 1 antib...

Platelets

...e a Closer Look at ITP:Find a Clinical Trial ... Platelets function by maintaining the integrity of the vascular tree, producing ... This exposes circulating platelets to subendothelial collagen and multimers of ... American Red Cross Northern California Blood Services Region web page ... Transfusi...

Liposomes

...Agents, ... Drug delivery with liposomes as carrier systems provide options and ... Liposomes as a drug carrier system has been utilized as circulating units for ... ...

Library

...information, library news, and more. Largest research library with a circulating system in the world. Strives to promote high-quality library and infor...formation needs of the state government. Located ... Besides acting as a circulating library for the Boston area (25 branches), BPL ... Affiliates of the Lib...
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