Needling Chromosomes Reveals Cell Division Secret
By impaling individual chromosomes with glassneedles one thousandth the diameter of a human hair, a Duke Universitygraduate student has tested their "stickiness" to one another duringcell division. Her uncanny surgical skills have added a piece to thelarge and intricate puzzle of how one cell divides into two -- aprocess fundamental to all organisms.In the Dec. 14, 2004, issue of Current Bi...Variation in women's X chromosomes may explain differences among individuals, between sexes
The first comprehensive survey of gene activity in the X chromosomes of women has revealed an unexpected level of variation among individuals, according to new work by researchers at the Duke University Institute for Genome Sciences & Policy (IGSP) and Pennsylvania State University. The results may have important implications for understanding the differences in traits among women and...Scientists analyze chromosomes 2 and 4
A detailed analysis of chromosomes 2 and 4 has detected the largest "gene deserts" known in the human genome and uncovered more evidence that human chromosome 2 arose from the fusion of two ancestral ape chromosomes, researchers supported by the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), reported today. In a study published in the Apr...Mouse to man: The story of chromosomes
The complete sequencing of human chromosome 17 and mouse chromosome 11 offers unique insights into the evolution of the genome of higher mammals, said a Baylor College of Medicine researcher who participated in this effort reported in today's issue of the journal Nature. The work represents the first time that a mouse chromosome has been completely sequenced and annotated, said Dr. James...Researchers use multiphoton microscopy to watch chromosomes in action
Feverish fruit fly larvae, warmed in a toasty lab chamber, are giving Cornell researchers a way to watch chromosomes in action and actually see how genes are expressed in living tissue. Using multiphoton fluorescence microscopy, a technique pioneered at Cornell by physicist Watt W. Webb, researchers have for the first time been able to watch chromosomes change their form in order to activa...Electroporation of Yeast Artificial Chromosomes
Maren Bell and Robert Mortimer, Human Genome Center, Divisionof Cell and Molecular Biology, Lawrence Berkeley Laboratory,Berkeley, California 94720 Transformation of yeast with yeast artificial chromosomes (YACs) has traditionally been performed by a PEG-spheroplast procedure. However, the...Chromosomes to predict oral cancer
The DNA content in cells of oral leukoplakia, specifically the number of chromosomes, can be used to predict the risk of oral carcinoma, according to study.// 123 patients were taken up for research for an average of 8.5 years, found that oral leukoplakia with the normal number of chromosomes — 46 — were unlikely to develop into cancer. Of the 103 patients with leukoplakia with normal DNA content...Disease chromosomes identified
Scientists working on the 10-year international Human Genome Project (HGP) have identified chromosomes which are believed to carry the highest concentration of disease genes.Out of 23 pairs of human chromosomes, 3 are believed to be associated with genetic disease. Over the next 20 years the research at the Wellcome Trust's Sanger Centre, near Cambridge, eastern England will have a la...Disease chromosomes identified
Scientists working on the 10-year international Human Genome Project (HGP) have identified chromosomes which are believed to carry the highest concentration of disease genes.Out of 23 pairs of human chromosomes, 3 are believed to be associated with genetic disease.Over the next 20 years the research at the Wellcome Trust's Sanger Centre, near Cambridge, eastern England will have a large impact on...Missing Chromosomes Revealed Brain Tumor Therapy Effect – Research Find
Study results have uncovered that missing portions of 2 chromosomes located at 1p and 19q predicted the prognosis of Brain tumor therapy//. The senior author Walter J. Curran Jr., M.D., professor and chair of radiation oncology at Jefferson Medical College of Thomas Jefferson University in Philadelphia, have found a paradigm shift in managing rare, malignant but treatable brain tumors a...Using Multiphoton Microscopy to See Chromosomes in Action
Feverish fruit fly larvae, warmed in a toasty lab chamber, are giving Cornell researchers a way to watch chromosomes in action and actually see how genes are expressed in living tissue.// Using multiphoton fluorescence microscopy, a technique pioneered at Cornell by physicist Watt W. Webb, researchers have for the first time been able to watch chromosomes change their form in order to...