New Therapies Could Change Organ Transplants
...cipient. Both procedures also involved transplanting donor stem cells into the recipient.
"The ability to achieve tolerance in what's called stable chimerism
[when donor cells are present in the recipient] in patients has been postulated since the 1960s," said Dr. Roy Smythe, chairman of surgery at Texas A&...
Chimerism in Medical Products
Transplantation Chimerism by PCR
Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Chimerism in Biological News
Recipe for capturing authentic embryonic stem cells may apply to any mammal, study suggests
... (The cocktails include inhibitors of GSK3, MEK, and FGF receptor tyrosine kinases.)
Most importantly, the isolated cells can produce high rates of chimerism
when reintroduced into early stage embryos and can transmit through the germline, they report.
" In the past two decades, embryonic stem cells have ...
Tandem transcripts team together
...uary issue of the journal Genome Research , two teams of scientists describe a widespread phenomenon in the human genome called transcription-induced chimerism
(TIC), where two adjacent genes produce a single, fused RNA transcript. The work has implications for drug development, as well as for understanding ...