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Chemotherapeutic in Medical News

Abbott and Oasmia Pharmaceutical Announce Exclusive Distribution Agreement for Paccal(R) Vet, a New Chemotherapeutic Agent for Dogs

ABBOTT PARK, Ill. and UPPSALA, Sweden, July 10 /PRNewswire-FirstCall/ -- Abbott (NYSE: ABT ) and Oasmia Pharmaceutical have announced a multi-year agreement to market one of the first cancer medications for dogs. The chemotherapeutic agent, called Paccal(R) Vet (micellar paclitaxel), represents ...

An adjuvant chemotherapeutic agent in gastric cancer therapy

Peritoneal carcinomatosis can be thought of as a series of events that together form a peritoneal metastatic cascade. The peritoneal stromal tissue appears to be a friendly host for tumour proliferation, providing a rich source of growth factors and chemokines known to be involved in tumour metast...

A new chemotherapeutic target for hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a major health problem worldwide. Currently, the only chance for obtaining a cure in patients with HCC is by either a surgical resection or liver transplantation. However, many HCCs with scattered tumors cannot be operated on. In such patients, effective alternati...

Cytokine IL6 as a New Chemotherapeutic Target for Ras-driven Cancers

Dr. Christopher Counter and colleagues at the Duke University Medical Center have identified IL6 as a new target in the battle against Ras-induced cancers . Ras is a key intracellular messenger protein that directs, among other things, cell growth and proliferation. Over-expression of the Ras ...

Bionovo Presents Positive Results from Phase 1B Trial of Bezielle for Metastatic Breast Cancer

... "We are eager to advance Bezielle to Phase 2 clinical testing as the drug continues to have an improved safety profile over currently available chemotherapeutic agents, and shows encouraging clinical activity in a cohort of women who have been heavily pretreated for metastatic breast cancer," said Dr. Mary Tag...

Nexavar in Combination with Chemotherapy Shown to Extend Progression-Free Survival in Patients with Advanced Breast Cancer

... Breast Cancer Trial Design The randomized, double-blind, placebo-controlled Phase 2 study evaluated Nexavar in combination with the oral chemotherapeutic agent, capecitabine, in 229 patients. These patients had locally advanced or metastatic HER-2 negative breast cancer and had received no more than one...

RI Hospital first in country to enroll patient in new study for recurrent chest wall breast cancer

...called the DIGNITY Study. The study will investigate the effectiveness of a chemotherapeutic agent, ThermoDox, used in conjunction with mild hyperthermia (a form of hea...e DIGNITY study that will test 100 patients nationally with an encapsulated chemotherapeutic agent called ThermoDox combined with hyperthermia treatment. ThermoDox is a...

Research identifies successful new treatment for Hodgkin's lymphoma, reduces long-term risks

...based treatment algorithm. Only nine weeks of chemotherapy were required in 63 percent of our patients. This study has shown conclusively that the new chemotherapeutic treatment of ABVE-PC simultaneously provides high efficacy and reduces the cumulative doses of chemotherapy and radiation. We believe this represents ...

Fluorescent probes may permit monitoring of chemotherapy effectiveness, Stanford study shows

... apoptosis light up, but not the healthy surrounding tissues. The potential for practical payoffs is significant, Bogyo said. Radiotherapy and many chemotherapeutic selectively damage DNA in rapidly replicating cells, dramatically boosting the amount of apoptotic death happening in tumors. Some experimental models...

European Medicines Agency (EMEA) Approves Cell Therapeutics, Inc.'s September Meeting Request to Discuss OPAXIO(TM) Marketing Authorization Application

...About OPAXIO(TM) OPAXIO(TM) (paclitaxel poliglumex, CT-2103), which was formerly known as XYOTAX(TM), is an investigational, biologically enhanced, chemotherapeutic that links paclitaxel, the active ingredient in Taxol(R), to a biodegradable polyglutamate polymer, which results in a new chemical entity. When bound...
Chemotherapeutic in Medical Technology

Pixantrone Increases Progression-Free Survival by 81% Compared to Standard Chemotherapeutic Agents in Phase III Relapsed Aggressive non-Hodgkin's Lymphoma Trial

SEATTLE, Jan. 28 /PRNewswire-FirstCall/ -- Cell Therapeutics (CTI) (Nasdaq and MTA: CTIC) announced today preliminary progression-free survival (PFS) results from its pivotal phase III EXTEND (PIX301) trial of pixantrone that show patients with advanced, relapsed aggressive non-Hodgkin's lymph...

Zila Inc. Product Selected to Identify Pre-Cancer in Study of Leading Cancer Treatment Chemotherapeutic - ERBITUX

- ViziLite Plus with TBlue630 - PHOENIX, Sept. 4 /PRNewswire-FirstCall/ -- Zila, Inc.'s (Nasdaq: ZILA ) ViziLite(R) Plus with Tblue630(TM) screening system for early detection of abnormalities which can lead to oral cancer, has been selected to identify pre-cancerous lesio...

OPAXIO(TM) Combined with Alimta(R) Well Tolerated in Dose-Ranging Study of Patients with Advanced Non-Small Cell Lung Cancer

... About (product) OPAXIO(TM) (paclitaxel poliglumex, CT-2103), which was formerly known as XYOTAX(TM), is an investigational, biologically enhanced, chemotherapeutic that links paclitaxel, the active ingredient in Taxol(R), to a biodegradable polyglutamate polymer, which results in a new chemical entity. When bound...

Lilly and New York City Mayor Michael R. Bloomberg Announce Lilly Agrees to be First Tenant of East River Science Park; Issue Urgent Call for Healthcare Reform that Protects Innovation and Jobs

...aluate the effect of IMC-1121B on the overall survival of patients with metastatic gastric cancer following disease progression on standard first-line chemotherapeutic regimens. This pivotal trial will be conducted at approximately 250 academic research centers across five continents. "This is an important ...

Oncolytics Biotech(R) Inc. Announces Publication of Research on Synergistic Activity of Reovirus and Chemotherapy in NSCLC

...e paper, entitled "Synergistic Antitumor Activity of Oncolytic Reovirus and chemotherapeutic Agents in Non-Small Cell Lung Cancer Cells" appears online in the July 14, ... the oncolytic activity of reovirus can be potentiated by taxanes and other chemotherapeutic agents, and that the reovirus-taxane combination most effectively achieves ...

Alfacell Provides Shareholder Update

...hat there are specific chemotherapy resistance genes which not only are present in untreated mesotheliomas but also become over expressed when certain chemotherapeutic agents, including platinum, are used in the first line therapy of cancer. These genes, known as the multidrug resistance (MDR) gene1 and the multidrug...

Paclitaxel Poliglumex (OPAXIO(TM)) Added to Cisplatin and Radiation Produces 45% Pathologic Complete Remissions in Patients With Esophageal Cancer

...inical studies have demonstrated that, unlike standard paclitaxel and other chemotherapeutic agents that enhance radiation killing by a factor of 1.5 to 2.0, OPAXIO inc...formerly known as XYOTAX(TM), is an investigational, biologically enhanced, chemotherapeutic that links paclitaxel, the active ingredient in Taxol(R), to a biodegradabl...

Proteolix Presents Positive Clinical Data for Carfilzomib in Multiple Myeloma at the 2009 ASCO Annual Meeting

...20,500 new cases of multiple myeloma will be diagnosed in the United States. Newly diagnosed patients have treatment options that include combination chemotherapeutic agents and stem cell transplantation. While many patients respond to treatment, most eventually relapse and require subsequent treatment. Few patien...

Pixantrone Phase 3 Data to be Presented at the 2009 American Society of Clinical Oncology (ASCO) Annual Meeting

...be held from 2:00 PM-6:00 PM Eastern Time. The presentation, abstract #8523, is titled, "Randomized Phase III trial of pixantrone compared with other chemotherapeutic agents for third-line single-agent treatment of relapsed aggressive non-Hodgkin's lymphoma." The abstract is available at www.asco.org . CTI ...

Phase 3 Trial of Nexavar in Chemotherapy-Naive Patients with Advanced Melanoma Does Not Meet Primary Endpoint

...patients receiving Nexavar in combination with the chemotherapeutic agents carboplatin and paclitaxel versus patients receiving placebo plus the chemotherapeutic agents. The treatment effect was comparable in ea...Nexavar twice daily or placebo, in addition to two chemotherapeutic agents - carboplatin and paclitaxel. Following 10...
Chemotherapeutic in Medical Products

Pocket Guide to Colorectal Cancer Drugs and Treatment

Features:...logy, and trends; staging and primary surgical management; adjuvant therapy; and treatment of advanced disease Specific information about each of the chemotherapeutic agents used in systemic treatment as adjuvant therapy of treatment of advanced disease is presented for both the nurse and patient/family The referen...
Company:Skyscape, Inc.
Chemotherapeutic in Medical Dictionary

Mouth sores

...tes ... Various types of sores can appear anywhere within the mouth , including the inner cheeks, gums, ... might cause mouth sores include chemotherapeutic agents ... Mouth sores - Overview, Various types of sores can appear anywhere within the mouth , including the inner cheeks, gums, tongue, ...

Chemotherapy

...ers includes symptoms, cancer detection and prevention, and treatment options. ... Chemotherapy : 1. ... Conventional chemotherapy includes chemotherapeutic agents and regimens that ... Patients may receive conventional chemotherapy as their only therapy, or they ... ... ever read on chemotherapy ."...
Chemotherapeutic in Biological News

Protein handlers should be effective treatment target for cancer and Alzheimer's

...ould be used for limited periods to avoid trading cancer for an increased risk of neurodegenerative disease or vice versa. "A lot of drugs, such as chemotherapeutic agents, can kill cancer but they also kill normal tissue. That is a limiting factor. We are looking for better drugs," she says. The MCG center is...

Tumor growth and chemo response may be predicted by mathematical model

... whether a prescribed drug will reach the tumor in sufficient quantities to kill the malignant cells. "We seek to improve the precision of prescribing chemotherapeutic drugs, since it is sometimes hard to tell which will work and which will not, and what the optimal dose is for a particular patient," said Hermann Fri...

TGen researchers discover possible way to block the spread of deadly brain tumors

... ensure that all of the invading tumor cells are gone, even when surgery is followed by radiation treatments and conventional anti-cancer drugs. "A chemotherapeutic treatment which targets these migrating cells would therefore have significant ramifications on patient survival," said Dr. Jennifer M. Eschbacher, a ...

Scripps scientists find structure of a protein that makes cancer cells resistant to chemotherapy

...the future, scientists may be able to use these crystal structures to design chemicals that block P-glycoprotein's activity and restore sensitivity to chemotherapeutic agents." Solving the Structure The team, which included scientists from Texas Tech University Health Sciences Center as well as Scripps Resear...

Updated formula measures kidney function more accurately

...termine if such a formula will apply to children and infants with higher levels of kidney function, so that any harm that might come from antibiotics, chemotherapeutic drugs and dehydration can be minimized in these populations as well." ...

UNC study: Tinkering with the circadian clock can suppress cancer growth

...ernal clock of each cancer cell to render it more vulnerable to attack with chemotherapeutic drugs. "Adjusting the clock in this way could certainly be a new targe...hat is when a particular enzyme system one that can reverse the actions of chemotherapeutic drugs is at its lowest levels in the body. ...

Stroma genomic signature predicts resistance to anthracyclin-based chemotherapy in breast cancer

...t a particular woman has a high probability of not responding to an anthracyclin-based therapy, this clinician may consider prescribing an alternative chemotherapeutic regimen. Moreover, this study suggests that predicting how individual patients might respond to chemotherapy could be possible, which raises hopes th...

Scattered light rapidly detects tumor response to chemotherapy

...r cell samples, researchers can determine if cancer cells are responding to chemotherapeutic agents within a matter of hours. Most chemotherapy drugs work by forcing... number of cells in a short time. "Now, oncologists typically judge if a chemotherapeutic agent is working by looking for shrinkage in the tumor using imaging techni...

New technique images tumor vessel leakiness to predict breast cancer chemotherapy outcome

...t agent reaches the tumor, we can predict how much of a clinically approved chemotherapeutic will reach the tumor, allowing physicians to personalize the dose and predi...roved chemotherapy drug, liposomal doxorubicin. Results showed that the chemotherapeutic drug slowed the progress of the tumor. The variability in uptake of the con...

TGen Clinical Research Services at Scottsdale Healthcare and Mayo Clinic study new cancer drug

...of oxygen). The drug candidate may provide an opportunity to treat slowly dividing tumor cells within hypoxic regions that generally evade traditional chemotherapeutic agents and ultimately contribute to relapse," Dr. Weiss said. Phase 1 and Phase 1/2 trials are underway to investigate the safety and activity of ...
Chemotherapeutic in Biological Technology

Study From the University of Texas M.D. Anderson Cancer Center Demonstrates That AHCC(R) is Safe in Combination With Most Chemotherapeutic Agents

Supports safety of AHCC for cancer patients undergoing chemotherapy PURCHASE, N.Y., Nov. 6 /PRNewswire/ -- A recently published study in the Journal of the Society for Integrative Oncology (Vol. 6, No. 3 (Summer), 2008: pp 105-109) by researchers at the University of Texas M.D. Anderson Ca...

Data Published in Cell Stem Cell Demonstrates Potent Anti-Cancer Activity for OncoMed Pharmaceuticals' Lead Antibody

...f OMP-21M18 alone and in combination with approved chemotherapeutic agents versus chemotherapy alone on the frequency ... as a single agent or in combination with standard chemotherapeutic agents significantly decreases the ratio of cancer...r, these data indicate that treatment with certain chemotherapeutic agents alone may actually serve to amplify the ris...

The Breast Cancer Therapeutics Market in Australia

...ent. These therapies are specifically designed to target cancer cells, while minimizing the adverse effects on normal cells when compared to cytotoxic chemotherapeutic drugs. New offerings must constitute therapies that will improve quality of life and survival rates if they are to thrive in this highly competitive m...

Champions Biotechnology Partners with Do-Coop Technologies to Advance Its Novel Oncology Compound Into Biomerk Tumorgraft(TM) Testing

...aft models to target microtubule associated protein tau (MAPT) deficient tumors with promising results as compared to a currently marketed and leading chemotherapeutic drug. These antimitotic inhibitors target MAPT (Microtubule-Associated Protein Tau) deficient tumors. In both in vitro and in vivo models, SG410 has d...

Cynvec to Present at The 2009 New York Venture Summit

...ol of Medicine, Cynvec is developing its lead product, CYN 101, to be used as a single agent or in combination with cytotoxics, monoclonal antibodies, chemotherapeutic agents and radiation. CYN 101 is a replication defective, apoptotic RNA vector that has shown tumor eradication and highly significant survival rates ...

Proteolix Presents Clinical Data from Two Clinical Studies of Carfilzomib in Multiple Myeloma at the 14th Congress of the European Hematology Association

...20,500 new cases of multiple myeloma will be diagnosed in the United States. Newly diagnosed patients have treatment options that include combination chemotherapeutic agents and stem cell transplantation. While many patients respond to treatment, most eventually relapse and require subsequent treatment. Few patien...

Cynvec to Present at the 11th Annual Shanghai International Forum on Biotechnology and Pharmaceutical Industry

...ol of Medicine, Cynvec is developing its lead product, CYN 101, to be used as a single agent or in combination with cytotoxics, monoclonal antibodies, chemotherapeutic agents and radiation. CYN 101 is a replication defective, apoptotic RNA vector that has shown tumor eradication and highly significant survival rates ...

Laboratory Test May Predict Effectiveness of ERBITUX(R) for Individual Colorectal Cancer Patients

...for response would be of great clinical utility. ChemoFx(R) is a test that measures an individual cancer patient's probable tumor response to various chemotherapeutic and biologic agents -- providing both sensitivity and resistance information. As such, ChemoFx(R) provides valuable insights that can help guide phys...

Micromet Presents Update at ASCO 2009 on a Phase 1b Combination Study of Adecatumumab and Docetaxel

...and autoimmune diseases, presented data from a clinical trial investigating its anti-EpCAM human antibody adecatumumab (MT201) in combination with the chemotherapeutic docetaxel in patients with metastatic breast cancer (MBC) at the annual meeting of the American Society of Clinical Oncology (ASCO) held in Orlando, F...

Access Pharmaceuticals Announces the European Launch of MuGard(TM) by its European Partner, SpePharm

...s targeted to breast cancer; Prodrax(R), a non-toxic prodrug which is activated in the hypoxic zones of solid tumors to kill cancer cells; Alchemix, a chemotherapeutic agent that combines multiple modes of action to overcome drug resistance. Access is also developing Phenylbutyrate ("PB"), an HDAC inhibitor and diffe...
Chemotherapeutic in Biological Definition

Antibiotic

...st bacteria. New antibiotics were rapidly discovered and came into widespread use, and a new era of research into the possibility of similarly "magic" chemotherapeutic cures for other diseases eventually led to successes in the field of cancer chemotherapy. The discovery of antibiotics, along with anesthesia and...
Chemotherapeutic in Biological Dictionary

Antimicrobial agent

... agents (systemic antibiotics (if needed), povi ... A. ANTIMICROBIAL chemotherapeutic AGENTS ... Antimicrobial agents also vary in their spectrum. ... of common antimicrobial chemotherapeutic agents listed by ... Plant Products as Antimicrobial Agents . MARJO...

Antibiotic

...her antibiotic , for example, is tetracycline (brand names: Achromycin and ... ANTIBIOTIC , ... More specifically, an antibiotic is a type of chemotherapeutic agent, that is, a ... Traditionally, the term antibiotic was applied to a ... Antibiotic resistance rates in Tennessee are among the highest in...
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(Date:12/15/2009)... scientists have found the first potential immunological clue of ... the pandemic H1N1 virus. , The study analyzed ... 15 outpatients and 15 control subjects in 10 Spanish ... August 2009. Researchers from the Hospital Clinico Universitario de ... high levels of a molecule called interleukin 17 in ...
(Date:12/15/2009)... ATLANTA, GADecember 15, 2009Do good-looking people really benefit from ... researchers from the University of Georgia and the University ... to have more social relationships and therefore an increased ... and might be why we spend billions of dollars ... study, published in this month,s issue of Personal ...
(Date:12/15/2009)... Leading Workers, Compensation Carrier Confirms PMSI as Solution Provider ... ... Tampa, FL (Vocus) December 15, 2009 -- PMSI, ... providers of specialty products and services for the workers’ ... (KEMI) has decided to renew its pharmacy services (retail ...
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(Date:12/15/2009)... study finds , , TUESDAY, Dec. 15 (HealthDay News) -- Tight ... with type 2 diabetes who have other medical problems, a ... in type 2 diabetes "has been a subject of controversy ... medicine at the University of California at Irvine, and lead ... the Annals of Internal Medicine . "Our work attempts ...
Breaking Medicine News(10 mins):Health News:First immunological clue to why some H1N1 patients get very ill or die 2Health News:The importance of attractiveness depends on where you live 2Health News:KEMI Renews Contract With PMSI 2Health News:Tighter Blood Sugar Control Not Best for Some Diabetics 2Health News:Tighter Blood Sugar Control Not Best for Some Diabetics 3
(Date:12/13/2009)... Yale University researchers has used nanosensors to measure ... time. Their findings, which appear December 13 in ... , could dramatically simplify the way physicians test ... , The teamled by Mark Reed, Yale,s ... and Tarek Fahmy, an associate professor of biomedical ...
(Date:12/11/2009)... global "green" trend, educators worldwide are relying ... students, science knowledge. Studies have revealed that ... not just science scoresenvironmental-based lessons can also ... areas. Naturally, educators are interested in developing ... into the classroom in hopes of piquing ...
(Date:12/11/2009)... school children understand that green plants photosynthesize, absorb ... the profound global-scale effects that photosynthesis has had ... on the origins and evolution of photosynthesis is ... School of Life Sciences. , Oxygen, one of ... cyanobacteria and their descendants (including algae and higher ...
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