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Chemopreventive in Medical News

Asian spice could reduce breast cancer risk in women exposed to hormone replacement therapy

...d VEGF secretion from breast cancer cells, Hyder said. "Curcumin and other potential anti-angiogenic compounds should be tested further as dietary chemopreventive agents in women already exposed to hormone replacement therapy containing estrogen and progestin in an effort to decrease or delay the risk of breast ...

Experimental agents may prevent radiation-induced leukemia

...ientists as ethane-1-hydroxy-1, 1-biphosphonate (EHBP) and carballylic amido bis phosphonic acid (CAPBP). Biphosphonates have emerged as an attractive chemopreventive agent due to earlier research that suggests they prevent bone metastasis and because they have an ability to remove uranium from the body. For the...

Long-term L-carnitine supplementation prevents development of liver cancer

...efore, carnitine supplementation alone or in combination with other natural chemopreventive compounds could be used to prevent, slow or reverse the occurrence of liver... which carnitine supplementation alone or in combination with other natural chemopreventive compounds could be used to prevent, slow or reverse the occurrence of liver...

Drug Inhibits Colon Cancer in Mice

... Florida. The findings, coupled with the fact that the drug appears to have minimal side effects, suggest that enzastaurin might offer an effective chemopreventive treatment in people at high risk for colon cancer, the researchers said. The study is to be published in the Feb. 15 issue of the journal Cancer Rese...

Maslinic acid provides a natural defense against colon cancer

...ti-tumoral and pro-apoptotic effects of maslinic acid against colon-cancer. chemopreventive agents of a natural origin, often a part of our daily diet, may provide a c...e to the development of maslinic acid for use as cancer chemotherapeutic or chemopreventive agents. ...

DFMO may affect Barrett's esophagus

...al target of DFMO, which suggests a potential mechanism contributing to the chemopreventive effects of DFMO," Sinicrope said. "KLF5 has been shown to regulate prolifer... problems related to treatment. "DFMO warrants further evaluation as a chemopreventive agent in patients with Barrett's esophagus and mucosal dysplasia," Sinicrop...

Adalimumab may reduce health-care costs for Crohn's disease patients

...a, weight loss and occasional bleeding. 5-ASA's chemopreventive Role: No Effect In longstanding patients with...ress where in this process compounds might exert a chemopreventive effect, but it also allowed them to account for ch...exposure over time, an underappreciated concept in chemopreventive literature." Three groups of UC patients were i...

NSAIDs: Painkillers, inflammation inhibitors, anti-cancer drugs and new de-methylating agents

...independent effects are also important for the inhibition of cancer development by NSAIDs. Indeed, NSAIDs are considered as a novel class of effective chemopreventive drugs. The research team, led by Wen-Chun Hung, Dean of College of Science, National Sun Yat-Sen University, and a recent doctorial graduate Mei-Re...

Soy compound may halt spread of prostate cancer

...gan said. Certain chemicals have beneficial effects and now we have all the preclinical studies we need to suggest genistein might be a very promising chemopreventive drug. Bergan and his team have previously demonstrated in prostate cancer cell cultures that genistein inhibits detachment of cancer cells from a p...

Indian medicinal plant Acanthus ilicifolius may combat liver cancer

...rology (volume 13, issue 48) addresses this problem. The research team led by Prof. Malay Chatterjee from Jadavpur University investigated the primary chemopreventive mechanisms of Acanthus ilicifolius in an in vivo tumor-transplanted murine model. A. ilicifolius, popularly known as Harkach Kanta is distributed wide...
Chemopreventive in Medical Technology

Onconase has Potential as Chemopreventive Agent in Mesothelioma, Reports World-Renowned Mesothelioma Researcher at AACR Annual Meeting

BLOOMFIELD, N.J., April 18, 2007 /PRNewswire-FirstCall/ -- ONCONASE (ranpirnase), Alfacell Corporation's lead drug candidate, may have potential as a chemopreventive agent, according to world-renowned mesothelioma researcher Michele Carbone M.D., Ph.D., at this week's American Association for Canc...
Chemopreventive in Biological News

Chemopreventive agents in black raspberries identified

... published in Cancer Prevention Research , a journal of the American Association for Cancer Research, identifies components of black raspberries with chemopreventive potential. Researchers at the Ohio State Comprehensive Cancer Center found that anthocyanins, a class of flavonoids in black raspberries, inhibited...

Selenium may prevent high risk-bladder cancer

...ose evolving through the p53 pathway, from developing, it gives us clues about how the tumors could be prevented in the future and potentially lead to chemopreventive efforts," Karagas said. Karagas hopes to replicate these findings on a larger scale in order to examine the connection between selenium and bladder...

Researchers discover atomic bomb effect results in adult-onset thyroid cancer

...ced cancer in humans, especially early steps and pathways, has potential implications for epidemiological risk analyses, early clinical diagnosis, and chemopreventive interventions," Hamatani said. He adds that there are several irradiated populations worldwide that have been shown to have an increase in thyroid ...

Natural compound in broccoli could treat devastating genetic skin disorder

.... -- The compound sulforaphane whose natural precursors are found at high levels in broccoli and other cruciferous vegetables has been hailed for its chemopreventive powers against cancer. Now sulforaphane has demonstrated new skills in treating a genetic skin blistering disorder called epidermolysis bullosa simple...

American Chemical Society's Weekly PressPac -- Sept. 19, 2007

...y injection to mice with prostate cancer. They also showed that urolithins inhibited the growth of human prostate cancer cells in cell culture. The chemopreventive potential of pomegranate ellagitannins and localization of their bioactive metabolites in mouse prostate tissue suggest that pomegranate may play a ro...

Plant-derived molecules, genetic manipulation point to future chemoprevention methods

...o stave off a variety of cancers. The latest studies with new and promising chemopreventive agents were presented at the American Association for Cancer Research's Fro...ere fed the compounds. The work bolsters the potential for these drugs as a chemopreventive agent for an increasing range of cancers. "We previously reported that...

COX-2 inhibitors significantly reduce risk of cancer

...n Association for Cancer Research in Washington, D.C. "We believe this is the first study to show that selective COX-2 inhibitors have significant chemopreventive effects against breast cancer," says Dr. Randall Harris, professor and director of the Center for Molecular Epidemiology and Environmental Health in T...

Inflammation and drugs to control this activity studied in a variety of tumors sites

...gainst adenomas," Daugherty said. She noted that previous research in animals has shown that AMACR modifies a component of ibuprofen that enhances its chemopreventive effects. "This is the first study to corroborate the biological data at a statistical level in humans," she said. Her team's results need to be...

Antioxidant selenium offers no heart-disease protection

... Selenium does not protect against cardiovascular disease, despite its documented antioxidant and chemopreventive properties, analysis of a randomized placebo-controlled clinical trial covering 13 years has shown. The selenium-CVD association was a secondary endpo...

Anti-cancer Compound In Beer Gaining Interest

...gnificantly increase the levels of xanthohumol or use it as a nutritional supplement - that might be different. It clearly has some interesting cancer chemopreventive properties, and the only way people are getting any of it right now is through beer consumption." Xanthohumol was actually first discovered in 1913...
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