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Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer

For patients with high-risk breast cancer treated with radical mastectomy and adjuvant chemotherapy, the addition of radiation therapy leads to better survival outcomes with few long-term toxic effects, according to a 20-year follow-up of a randomized trial, which appears in the January 19 issue of the Journal of the National Cancer Institute. The British Columbia randomized radiation the...

New Treatment Rivals Chemotherapy For Lymphoma, Study Finds

A new form of treatment for lymphoma that takes a fraction of the ti...

Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer

Preliminary results from a large, randomized clinical trial for patients with previously untreated recurrent or metastatic breast cancer ?cancer that has spread from the breast to other parts of the body ?show that those patients who received bevacizumab (Avastin? in combination with standard chemotherapy had a longer time period before their cancer progressed than patients who received the same...

USC researchers determine mechanism of action of chemotherapy drug

The chemotherapy drug motexafin gadolinium (brand name: Xcytrin, manufactured by Pharmacyclics, Inc.) works to thwart cancer cells by disrupting key enzymes involved in cellular metabolism, according to a team of researchers led by Joseph Hacia, Ph.D., assistant professor of biochemistry and molecular biology at the Keck School of Medicine of the University of Southern California. The cell...

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

When it comes to the deadly skin cancer melanoma, studying functional tissue rather than cell lines may better provide insight into the disease's development, according to new research from a Howard Hughes Medical Institute predoctoral fellow at Stanford University School of Medicine. Though multiple genetic alterations are associated with melanoma development, scientists have not been abl...

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The development of a CXCR2 chemokine receptorbinding assay using the LEADseeker Multimodality Imaging System

CXCR2 • GPCR • receptor binding assay • LEADseeker • SPA Imaging Beads Chemo-attractant cytokines (chemokines) are low molecular weight, pro-inflammatory cytokines with potent leukocyte activation and/or chemotactic activity (1). Chemokines are classified into four families (CXC, CC, C, and CX...
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Acupuncture May Help Chemotherapy Side Effects

Oriental medical practice of Acupuncture along with commonly used medications may help ease the distressing and disabling side effects of chemotherapy for breast cancer patients, if researchers at National Institute of Health (NIH) are to be believed. According to Dr. Joannieshen MD, MPH, research associate at NIH, electro-acupuncture was more effective in controlling vomiting than...

Chemotherapy Pill Has Fewer Side Effects Than IV

A chemotherapy pill is as effective for treating advanced colorectal cancer as intravenous treatment with a similar drug.Patients taking the pill capecitabine survived just as long as those on standard chemotherapy, but the pill caused fewer side effects.// Capecitabine is the oral form of 5-fluorouracil (5-FU), the chemotherapy regimen most commonly used to treat advanced colorectal cancer.<br...

Gossypol helps in chemotherapy of neck and head cancer.

Gossypol, a compound present in cottonseed has been found be increase the effectiveness of chemotherapy// for neck and head cancer patients. This could prove beneficial in cancer treatment and help patients worldwide. Shaomeng Wang, Ph.D., co-director of the Molecular Therapeutics Program at the U-M Comprehensive Cancer Centre, discovered gossypol, a compound derived from a component o...

Survival rates in breast cancer patients improved with "Dose Dense Chemotherapy"

A study conducted by the Cancer and Leukemia Group B (CALGB) and presented at the 25th Annual San Antonio Breast Cancer Symposium assessed the effectiveness of reducing the interval between successive doses of a commonly used chemotherapy regimen to improve survival rates in breast cancer// women. This study was conducted as follow-up of a mathematical model which was developed in the 1980s that...

Response to chemotherapy could be measured by Prostate-Specific Antigen Doubling Time

Researchers from the department of urology in a hospital in Switzerland who investigated whether chemotherapeutic response to hormone-refractory prostate cancer could be measured via changes in prostate-specific antigen (PSA) found that prostate cancer doubling time may be an auxiliary marker of response to chemotherapy// in patients with hormone refractory prostate cancer. The study...

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Physicians' Cancer Chemotherapy Drug Manual 2005

Description:Completely revised and updated for 2005, this practical handbook is an up-to-date guide to all aspects of cancer chemotherapy. The book provides a comprehensive, easy to use catalog of over 100 drugs both on and off label commonly used in cancer treatment. This new edition includes new agents (recently or about to be FDA approved)....
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Pocket Guide to Chemotherapy Protocols, 2nd Edition

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In Vitro and In Vivo Data Show Alfacell's Onocanse is Active Against Naive and Chemoresistant Neuroblastoma Cells

Pre-Clinical Results Demonstrate Potential of ONCONASE forTreatment of Neuroblastoma BLOOMFIELD, N.J., June 27, 2007 /PRNewswire-FirstCall/ --Alfacell Corporation today announced that new data show ONCONASE,the company's lead drug candidate, is active against naive andchemoresistant neuroblastoma cells. The pre-clinical in vitro and in vivo data published in CancerLetters (2007; Vo...

Pharmacyclics Announces Interim Results From Two Ongoing Phase 2 Trials Supporting Potential of Xcytrin Plus Chemotherapy to Treat Recurrent Non-Small Cell Lung Cancer

WAILEA, Hawaii and SUNNYVALE, Calif., June 27, 2007/PRNewswire-FirstCall/ -- Pharmacyclics, Inc. today announcedpreliminary results from two open-label, multi-center Phase 2clinical trials supporting the potential use of Xcytrin(R)(motexafin gadolinium) Injection, the company's lead productcandidate, in combination with Alimta(R) (pemetrexed) and incombination with Taxotere(R) (docetaxel...

July Issue of Journal of Antimicrobial Chemotherapy Highlights Study of Factive Tablets for Five-Day Treatment of Community-Acquired Pneumonia

WALTHAM, Mass.--(BUSINESS WIRE)--Jun 12, 2007 - Results from thesuccessful clinical trial of Oscient Pharmaceuticals' (Nasdaq:OSCI) FACTIVE(R) (gemifloxacin mesylate) tablets for the five-daytreatment of community-acquired pneumonia of mild to moderateseverity (CAP) have been published in the July issue of thepeer-reviewed Journal of Antimicrobial Chemotherapy, currentlyavailable in advance...

New Data Show Pfizer's Axitinib Prolonged Overall Survival in Advanced Pancreatic Cancer When Combined with Standard of Care Chemotherapy

CHICAGO--(BUSINESS WIRE)--Jun 4, 2007 - Pfizer announced today thataxitinib (AG-013736), an investigational oral, selective inhibitorof VEGFR 1, 2,3 (vascular endothelial growth factor receptors 1, 2,3) combined with gemcitabine showed a trend towards prolongedoverall survival (OS) in patients with advanced pancreatic cancer,compared with gemcitabine alone, according to preliminary data from...

Eloxatin (oxaliplatin injection)-Based Chemotherapy Sets New Treatment Benchmark in Patients With Metastatic Colorectal Cancer

FOLFOX4 Chemotherapy Results in Improved Long-term [Five-years]Overall Survival for these Seriously Ill Patients CHICAGO, June 04, 2007 /PRNewswire-FirstCall/ -- FOLFOX4, anEloxatin(R)-based chemotherapy regimen, provided significantimprovements in long-term [five- years] overall survival (OS) andtime to disease progression (TTP) - a longer period of stabledisease - in patients with metas...

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Chemotherapy

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(Date:8/29/2008)...esults of a 10-year study published in the August ...found that magnesium sulfate administered to women...he risk of cerebral palsy by 50 percent. The Benef...) trial was conducted in 18 centers in the U.S., i...renatal intervention ever found to reduce the inst...
(Date:8/29/2008)... http://www.aronowitzmd.com [Los An...espected experience in plastic surgery procedures ...consideration may be necessary for these patients,...e an established specialty of procedures for after...es, CA (PRWEB) August 29, 2008 -- Bariatric surger...
(Date:8/28/2008)...ues increase 138% versus Q2 2007 - Nine new Cen...RNewswire-FirstCall/ - CRH Medical Corporation,(CR... three and six months,ended June 30, 2008 (all fig...ths ended June 30, 2008 increased 138% to $1,653,8...7. Revenue for the six months ended June,30, 2008 ...
(Date:8/28/2008)...ion will be based in the Northeast region with mor...xt year, HARRISBURG, Pa., Aug. 28 /PRNewswire-USN...ity has hired a Patient Safety Liaison for the,Nor...eport to the,Pennsylvania Patient Safety Reporting...ylvania citizens., "Last year in focus groups wit...
Breaking Medicine News(10 mins):Health News:National study shows magensium sulfate reduces risk of cerebral palsy in premature births 2Health News:Dr. Joel Aronowitz, Specialist in Los Angeles Body Lift, Announces Plastic Surgery Options After Bariatric Surgery Weight Loss 2Health News:Dr. Joel Aronowitz, Specialist in Los Angeles Body Lift, Announces Plastic Surgery Options After Bariatric Surgery Weight Loss 3Health News:Dr. Joel Aronowitz, Specialist in Los Angeles Body Lift, Announces Plastic Surgery Options After Bariatric Surgery Weight Loss 4Health News:CRH Medical reports Q2 2008 results 2Health News:CRH Medical reports Q2 2008 results 3Health News:CRH Medical reports Q2 2008 results 4Health News:CRH Medical reports Q2 2008 results 5Health News:Pennsylvania Patient Safety Authority Hires Patient Safety Liaison to Help Healthcare Facilities Implement Guidance 2Health News:Pennsylvania Patient Safety Authority Hires Patient Safety Liaison to Help Healthcare Facilities Implement Guidance 3
(Date:8/28/2008)... , Quicker microwave meals that use less energy m...hes and, according to the material scientists resp...c waste remediation. , , "Currently, food heate...se the dishes are transparent to microwaves," says...y mineralogy, College of Agricultural Sciences at ...
(Date:8/28/2008)... , Researchers at The University of Nottingham ha...to develop a new drug that could ease the sufferin...ts who are unable to take beta-blockers. , In th... and most are able to have their symptoms effectiv...drugs which stop adrenaline from making the heart ...
(Date:8/28/2008)... , BIRMINGHAM, Ala. -- Intravenous magnesium su... the risk for handicapping cerebral palsy in half,...a at Birmingham (UAB) obstetrician Dwight Rouse, M...w England Journal of Medicine. , Cerebral palsy...ting control of movement and posture and limiting ...
(Date:8/27/2008)... ,, DALLAS Aug. 28, 2008 Researchers at UT...ce that the brain must create new nerve cells for ...ssion-like behavior. , In addition, the research...e same biochemical pathway to exert their effects.... mechanisms of antidepressants and provide a new d...
Breaking Biology News(10 mins):Ceramic material revs up microwaving 2New beta-blocker to offer hope to heart and lung sufferers 2Common treatment to delay labor decreases preterm infants' risk for cerebral palsy 2Common treatment to delay labor decreases preterm infants' risk for cerebral palsy 3Antidepressants need new nerve cells to be effective, UT Southwestern researchers find 2Why do astronauts suffer from space sickness 3F 20003 1Why do astronauts suffer from space sickness 3F 20003 2Lilly Announces Changes in Key Leadership Roles 20000 1Lilly Announces Changes in Key Leadership Roles 20000 2Lilly Announces Changes in Key Leadership Roles 20000 3Lilly Announces Changes in Key Leadership Roles 20000 4Lilly Announces Changes in Key Leadership Roles 20000 5VA Secretary Appoints Panel of National Suicide Experts 19997 1VA Secretary Appoints Panel of National Suicide Experts 19997 2 C O R R E C T I O N Rosetta Genomics Ltd 5557 1 C O R R E C T I O N Rosetta Genomics Ltd 5557 2 C O R R E C T I O N Rosetta Genomics Ltd 5557 3 C O R R E C T I O N Rosetta Genomics Ltd 5557 4 C O R R E C T I O N Rosetta Genomics Ltd 5557 5 C O R R E C T I O N Rosetta Genomics Ltd 5557 6 C O R R E C T I O N Rosetta Genomics Ltd 5557 7 C O R R E C T I O N Rosetta Genomics Ltd 5557 8 C O R R E C T I O N Rosetta Genomics Ltd 5557 9 C O R R E C T I O N Rosetta Genomics Ltd 5557 10 C O R R E C T I O N Rosetta Genomics Ltd 5557 11 C O R R E C T I O N Rosetta Genomics Ltd 5557 12 C O R R E C T I O N Rosetta Genomics Ltd 5557 13 C O R R E C T I O N Rosetta Genomics Ltd 5557 14 C O R R E C T I O N Rosetta Genomics Ltd 5557 15 C O R R E C T I O N Rosetta Genomics Ltd 5557 16 C O R R E C T I O N Rosetta Genomics Ltd 5557 17 C O R R E C T I O N Rosetta Genomics Ltd 5557 18 C O R R E C T I O N Rosetta Genomics Ltd 5557 19 C O R R E C T I O N Rosetta Genomics Ltd 5557 20
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