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Chemists in Medical News

Caltech chemists say antibody surrogates are just a 'click' away

Chemists at the California Institute of Technology (Caltech) and the Scripps Research Institute have developed an innovative technique to create cheap but highly stable chemicals that have the potential to take the place of the antibodies used in many standard medical diagnostic tests. James R...

IUPUI chemists develop Distributed Drug Discovery: Finding drugs for neglected diseases

INDIANAPOLIS Researchers from Indiana University-Purdue University Indianapolis (IUPUI) have developed Distributed Drug Discovery (D3), a new low-cost strategy to accelerate the discovery of drugs to treat neglected diseases such as tuberculosis, leprosy, leshmaniasis, dengue fever, and Chagas dis...

Waters Corporation Announces U.S. Drug Enforcement Administration Acquires Waters ACQUITY UPLC System to Train Forensic Chemists in Drug Screening and Profiling

MILFORD, Mass., April 29 /PRNewswire-FirstCall/ -- Waters Corporation (NYSE: WAT ) announced today that the United States Drug Enforcement Administration (U.S. DEA) purchased a Waters(R) ACQUITY(R) UltraPerformance Liquid Chromatograph for the purpose of training new forensic chemists at the...

Informex Invites Young Chemists to Attend InformexUSA

North America's Largest Chemical Industry Trade Fair Offers New Chemists and Chemical Engineers an Opportunity to Consider Innovation in the Chemical Industry PRINCETON, N.J., Dec. 12 /PRNewswire/ -- Informex today announced that it will invite young chemists to attend the upcoming Infor...

UCR chemists use 'green chemistry' to produce amines, chemical compounds used widely in industry

RIVERSIDE, Calif. Chemists at UC Riverside have discovered an inexpensive, clean and quick way to prepare amines nitrogen-containing organic compounds derived from ammonia that have wide industrial applications such as solvents, additives, anti-foam agents, corrosion inhibitors, detergents, dyes...

Brown chemists create cancer-detecting nanoparticles

PROVIDENCE, R.I. [Brown University] Magnetic resonance imaging (MRI) can be a doctor's best friend for detecting a tumor in the body without resorting to surgery. MRI scans use pulses of magnetic waves and gauge the return signals to identify different types of tissue in the body, distinguishing ...

Stevens chemists identify compounds to lure nutria, a rat-like pest ravaging Gulf Coast wetlands

HOBOKEN, N.J. A 10-pound rodent pest called nutria ravaging southern wetlands in the US, which has been especially damaging to the marshland ecology in the Mississippi Delta following Hurricanes Rita and Katrina, may have finally met its match thanks to molecular science that includes the work of...

Iowa State chemists track how drug changes, blocks flu virus

AMES, Iowa An anti-virus drug attacks influenza A by changing the motion and structure of a proton channel necessary for the virus to infect healthy cells, according to a recently published research paper by two Iowa State University chemists. Mei Hong, Iowa States John D. Corbett Professor in...

UIC chemists characterize Alzheimer's neurotoxin structure

Amyloid plaques, the hallmark of Alzheimer's disease, are clumps of fiber-like misfolded proteins which many experts think cause this devastating neurodegenerative disease. While effective treatment remains an elusive goal, new research by University of Illinois at Chicago chemists suggests a ...

Computers help chemists fight emerging infections

BOSTON, Aug. 19, 2007 Computer analysis of existing drugs may be key to fighting new infectious agents and antibiotic-resistant pathogens like deadly tuberculosis strains and staph superbugs. Researchers in Canada say the use of such emergency discovery technology could save time, money and lives...
Chemists in Medical Technology

One Step Closer: Novel Opioid Receptor Compound in Phase I Clinical Trials

... pharmacokinetic profile that could support once-daily dosing. "This latest discovery is the result of an interdisciplinary collaboration between chemists and biologists," Wentland said. "In the process, we are working together to identify novel therapies to treat human diseases and find possible solutio...

96-Well Filtration Plate From Varian, Inc. Improves Sensitivity and Precision for Trace Bio-Analysis by LC/MS

...ip 96-well plate specially designed to remove phospholipids including lysophosphatidylcholines, from biofluids. It is intended for use by analytical chemists in the pharmaceutical and life science industries performing quantitative and qualitative analyses of drugs in biofluids. In applications such as drug...

GeneGo is Awarded NCI Grant for Development of Systems Biology Platform for Integrative Data Analysis in Cancer

...sed on functional descriptors. "MetaMiner (Oncology) is a new generation pathway analysis tool, specifically tailored for biologists, clinicians and chemists working in different cancer areas," said Yuri Nikolsky, CEO of GeneGo and the grant's PI. "Neoplasms are tremendously complex diseases, with many hund...

ImQuest Publishes Results of Important Structure Activity Relationship Program on Dual Acting Pyrimidinediones

...nique compounds," explained Dr. Buckheit. Other coauthors on this paper include ImQuest virologists Tracy Hartman, Karen Watson and Lu Yang and Samjin chemists Ho-Seok Kwon, Sun-Hwan Lee, Jae-Woong Lee, Dong-Wook Kang, Sun-Gan Chung and Eui-Hwan Cho. ImQuest expects to submit an IND to initiate Phase 1 huma...

First High-Res 3-D Structures of Mammalian HSP90 Protein Solved, Key to Better Targets for AIDS, Sepsis, Cancer Drugs

... develop HSP90 inhibitors, the same potential exists here. "This will spur a new line of inquiry into GRP94. While this work is its infancy, medicinal chemists will be interested in developing GRP94-targeted drugs," Gewirth said. Other authors of the publication include: D. Eric Dollins, recent Ph.D. graduat...

Tainted Chinese Food Ingredients First Discovered in 2005

...osteoarthritis ingredient used today by millions of Americans to treat joint pain and stiffness, was deliberately adulterated with a chemical that TSI chemists could not even identify. "Our Chinese suppliers were profiting by tricking our testing techniques," said Joe Zhou, president of TSI international ope...
Chemists in Medical Definition

Medicine

...r he observed that bacteria took up toxic dyes that human cells did not. The first major class of antibiotics was the sulfa drugs, derived by French chemists originally from azo dyes. Throughout the twentieth century, major advances in the treatment of infectious diseases were observable in (Western) soci...
Chemists in Medical Dictionary

CHEM

...Dow Loses $486 Million, Cost Cuts Continue. So... Chem .Info Events Calendar ... Is an international monthly forum for papers of interest to both chemists and biologists. ... Chem -Way Corp. Divisions. Contract Packaging. Food Ingredients. Pool & Spa Chemicals ... The CEO and founder of Chem -W...
Chemists in Biological News

Dancing 'adatoms' help chemists understand how water molecules split

RICHLAND, Wash. -- Single oxygen atoms dancing on a metal oxide slab, glowing brighter here and dimmer there, have helped chemists better understand how water splits into oxygen and hydrogen. In the process, the scientists have visualized a chemical reaction that had previously only been talked ab...

UConn chemists find secret to increasing luminescence efficiency of carbon nanotubes

STORRS, Conn. - Chemists at the University of Connecticut have found a way to greatly increase the luminescence efficiency of single-walled carbon nanotubes, a discovery that could have significant applications in medical imaging and other areas. Increasing the luminescence efficiency of carbo...

Clemson chemists present revolutionary teaching concepts

CLEMSON Clemson University researchers want to strengthen chemistry skills starting at the molecular level and are introducing revolutionary ways for high school- and college-level educators to do that for students. Clemson chemistry professors Melanie Cooper and Gautam Bhattacharyya, along wi...

JHU chemists devise self-assembling 'organic wires'

From pacemakers constructed of materials that so closely mimic human tissues that a patient's body can't discern the difference to devices that bypass injured spinal cords to restore movement to paralyzed limbs, the possibilities presented by organic electronics read like something from a science ...

Smoke smudges Mexico City's air, chemists identify sources

Mexico City once topped lists of places with the worst air pollution in the world. Although efforts to curb emissions have improved the situation, tiny particles called aerosols still clog the air. Now, atmospheric scientists from UC San Diego and six other institutions have sorted through the pal...

NIST chemists get scoop on crude 'oil' from pig manure

After a close examination of crude oil made from pig manure, chemists at the National Institute of Standards and Technology (NIST) are certain about a number of things. Most obviously, "This stuff smells worse than manure," says NIST chemist Tom Bruno. But a job's a job, so the NIST team has...

Glowing films developed by UC San Diego chemists reveal traces of explosives

New spray-on films developed by UC San Diego chemists will be the basis of portable devices that can quickly reveal trace amounts of nitrogen-based explosives. Contaminated fingerprints leave dark shadows on the films, which glow blue under ultraviolet light. One of the films can distinguish be...

Biologists are from Mars, chemists are from Venus?

Plays well with others. That popular phrase on a T-shirt is being taken to a whole new level in higher education these days, as experts in a variety of fields increasingly must work together to address some of society's biggest challenges, from a warming planet to cancer. But how do scientis...

Team of chemists receives $5 million grant to develop enzyme mimics

EVANSTON, Ill. --- Mother Nature regulates critical cellular activities in plants and animals by using enzymes, catalysts that bring about specific biochemical reactions. Looking to learn from nature, a team of Northwestern University chemists has received a $5 million grant from the Air Force Off...

Good earth: Brown chemists show origin of soil-scented geosmin

PROVIDENCE, R.I. [Brown University] Brown University chemists have found the origins of an odor the sweet smell of fresh dirt. In Nature Chemical Biology, the Brown team shows that the protein that makes geosmin source of the good earth scent has two similar but distinct halves, each playing a...

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Chemists in Biological Technology

Brown chemists create more efficient palladium fuel cell catalysts

PROVIDENCE, R.I. [Brown University] Even small devices need power, and much of that juice comes from fuel cells. As these devices become even smaller, the rush is on to find more efficient ways to power them. In the last several years, scientists have discovered that palladium, a metal, is a s...

Northwestern chemists take gold, mass-produce Beijing Olympic logo

EVANSTON, Ill. --- Northwestern University nanoscientist Chad A. Mirkin has mass-produced the 2008 Summer Olympics logo -- 15,000 times. All the logos take up only one square centimeter of space. Mirkin and his colleagues printed the logos as well as an integrated gold circuit using a new prin...

Glowing films developed by UC San Diego chemists reveal traces of explosives

New spray-on films developed by UC San Diego chemists will be the basis of portable devices that can quickly reveal trace amounts of nitrogen-based explosives. Contaminated fingerprints leave dark shadows on the films, which glow blue under ultraviolet light. One of the films can distinguish be...

TIBCO Speeds Drug Discovery for Chemists

TIBCO Spotfire Lead Discovery provides an easy-to-use, highly visual and interactive environment for exploring chemical structures and any associated data SOMERVILLE, Mass., Nov. 11 /PRNewswire-FirstCall/ -- TIBCO Software Inc. (Nasdaq: TIBX ), today announced the release of TIBCO Spotfire(...

Sigma-Aldrich Acquires ChemNavigator, Inc., to Provide Researchers With Industry-Leading Chemical Compound Selection and Procurement Services

...ilable chemicals and procured for actual testing of their biological properties. ChemNavigator provides medicinal, computational and synthetic chemists with a comprehensive set of virtual screening tools and products that allows them to channel their chemical designs toward sets of commercially availa...

New clues about a hydrogen fuel catalyst

...nia borane, serves as a sort of structural support. The catalyst plucks the hydrogen from the ammonia borane as needed to run the device. The PNNL chemists in the Institute for Interfacial Catalysis study a rhodium-based catalyst that performs this job fairly well, but might have potential for improvement...

New method may accelerate drug discovery for difficult diseases like Parkinson's

...e assays and robotics, and defining the compounds' structures largely through trial and error. At the end of this months-long process, a large team of chemists and biologists usually deem only 1% or fewer of the compounds worthy of further testing in living cells. A novel method, demonstrated by Whitehead ...

Novel drug discovery tool could identify promising new therapies for Parkinson's disease

... Researchers funded by the National Institutes of Health have turned simple baker's yeast into a virtual army of medicinal chemists capable of rapidly searching for drugs to treat Parkinson's disease. In a study published online today in Nature Chemical Biology , the researcher...

Burnham Institute for Medical Research and Magellan BioScience Group, Inc. Announce Drug Discovery Collaboration

...squo;s state-of-the-art robotic screening system to run bioassays and characterize lead candidates from the collection. The Burnham team of Medicinal chemists will then optimize novel compounds to afford potential biological probes and preclinical drug candidates. The groups’ combined expertise in soph...

Bioinformatics Expert Dr. Jiaan Yang Joins Sundia MediTech With Innovative PFSC Technology

...method to describe protein complex 3D structure, and achieved PFSC, an outstanding success. For a long time, it has been a great challenge to protein chemists and biologists how to obtain a complete description of protein 3D structure, including the irregular shapes of loops and coils. With his expertise in...
Chemists in Biological Products

PsiPort ™ Mass Directed Auto Purification Software from Shimadzu Biotech

Description:...hput mass directed auto purification for synthetic chemists using a simple, intuitive, graphical user interfac...any intranet or over the Internet. Key features chemists and biochemists do not need to be trained on mass ...rmation Services). Sample log-in and acquisition chemists may submit samples either using a spreadsheet from...
Company:Shimadzu Biotech

PrepLCMS from Shimadzu

Description:...r both analytical and preparative operation. Switching between modes is simple - one click in the software. This support provides a quick solution for chemists optimizing the separation at the analytical scale before working up to preparative scale. It also offers isolation of up to 10 different components in...
Company:Shimadzu
Chemists in Biological Definition

Colchicine

...3 Toxicity 2.4 Laboratory use 3 External links History The colchicine alkaloid was first isolated in 1820 by the two French chemists P.S. Pelletier and J. Caventon (Pelletier PS, Caventon J. Ann. Chim. Phys. 1820;14:69). Colchicum extract was first described as a treatment for go...

Mathematical biology

...ic knowledge involved, biomathematical research is often done in collaboration between mathematicians, physicists, biologists, physicians, zoologists, chemists etc. Bibliographical references J.D. Murray, Mathematical Biology . Springer-Verlag, 3rd ed. in 2 vols.: Mathematical Biology: I. An Introdu...

X-ray crystallography

...s of Protein X-Ray Crystallography. Springer-Verlag Inc. NY: 1999, ISBN 0387985875 . Glusker JP, Lewis M, Rossi M. Crystal Structure Analysis for chemists and Biologists. VCH Publishers. NY:1994, ISBN 0471185434 . Rhodes G. Crystallography Made Crystal Clear. Academic Press. CA: 2000, ISBN 0125870...
Chemists in Biological Dictionary

Redox reaction

...reaction is redox ? ... have established for precipitation and acid reactions , it is likely to be redox . ... To indicate redox reactions , chemists typically write out the electrons explicitly: ... We can now combine the two (2) half- reactions to form a redox equation: ... We know that in ...

Native Gel

... electrophoresis (BNPAGE) is ... III. NATIVE ACRYLAMIDE GEL PREPARATION AND. ELECTROPHORESIS IN THE FIRST DIMENSION ... A site for protein chemists and others doing protein chemistry for the analysis and ... Native Gel Electrophoresis. First, make up the stock solutions ... Shop for skin ...
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