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Chemically in Medical News

Senokot(R) Tablets Undergo a Natural Makeover

...ne 28, at the National Association of Chain Drug Stores (NACDS) 2009 Marketplace Conference, in Boston. Newly reformulated Senokot(R) Tablets are not chemically processed, and the primary ingredient is the deseeded pod of the senna plant. (Photo: http://www.newscom.com/cgi-bin/prnh/20090806/NY57748 ...

Silenced genes as a warning sign of blood cancer

... started to check this. "This is probably most effective in a very early phase of methylation," Plass explains. The researchers believe that the first chemically deactivated genes trigger whole cascades of changes in the genetic material which can hardly be controlled at a later stage. Keyword: Epigenetics...

Quark Pharmaceuticals to Participate in IBC's Oligonucleotide Therapeutics: From Concept to Implementation Conference

...et tissues including the eye, ear, lung, spinal cord and brain. PF-4523655 (RTP801i-14), currently in Phase II clinical trials, is a synthetic, chemically modified siRNA designed to inhibit the expression of the gene RTP801 discovered by Quark through the gene discovery platform BiFAR. PF-4523655 is lice...

Drug-Device Combination Market Worth US$18.54 Billion by 2014

...ndmarkets.com/ Market-Reports/drug-and-device-combination-101.html ) includes all the products that are a combination of drugs and devices and can be chemically or physically united or co-packaged as separate, cross labeled products. The market is driven by the growing demand for treating only the ; targeted a...

Quark Pharmaceuticals Announces Data Indicating Potential Utility of QPI-1007 for Treatment of Glaucoma

...et tissues including the eye, ear, lung, spinal cord and brain. PF-4523655 (RTP801i-14), currently in Phase II clinical trials, is a synthetic, chemically modified siRNA designed to inhibit the expression of the gene RTP801 discovered by Quark through the gene discovery platform BiFAR. PF-4523655 is lice...

New Anesthesia May Be Safer for Critically Ill

... common general anesthesia has been developed that may be safer for some patients. Preclinical studies done on rats put under with MOC-etomidate, a chemically altered version of the anesthetic etomidate, found the drug does not cause blood pressure to drop suddenly or slow adrenal gland activity, common sid...
Chemically in Medical Technology

Cognition Therapeutics Closes Series A Financing to Advance Drug Candidates for Alzheimer's Disease

...ponses of mature primary neurons to the toxic proteins. Cognition's proprietary chemistry platform converts natural products into low molecular weight chemically stable druglike molecules, and is thus a source of novel pharmacophores and valuable drug candidates. These two technology platforms harken back to th...

Mayo Clinic Proceedings: A Comprehensive Review of Addiction to Prescription Painkillers Among Patients and Physicians

...ing, they add. New opioid formulas designed to minimize abuse are now in late-stage development and could help, Dr. Passik says. These drugs are chemically designed to diminish euphoric effects, thus possibly reducing problematic use. For now, responsibility coupled with expertise, insight, diligence and ...

Ferring Pharmaceuticals Unveils Six-Month Efficacy Data for EUFLEXXA(R) for the Treatment of Osteoarthritis Knee Pain

...). (3) Schiavinato A, Finesso M, Cortivo R, & Abatangelo G (2002). Comparison of the effects of intra-articular injections of Hyaluronan and its chemically cross-linked derivative (Hylan G-F20) in normal rabbit knee joints. Clin Exp Rheumatol 20, 445-454. (4) Goomer RS, Leslie K, Maris T, & Amiel ...

Quark Pharmaceuticals Presents at Asia TIDES Conference

...based on its intellectual property covering a host of novel structures. The chemically modified siRNA exhibits optimal activity and stability while attenuating po...523655 (RTP801i-14), currently in Phase II clinical trials, is a synthetic, chemically modified siRNA designed to inhibit the expression of the gene RTP801 discov...

Intra-Cellular Therapies Announces Successful Outcome of a Phase II Clinical Trial with ITI-007 in Patients with Sleep Maintenance Insomnia

... capable of generating a unique molecular signature for drug compounds. Specifically, CNSProfile(TM) measures the levels of phosphoproteins, proteins chemically linked at specific sites to phosphates. This profile provides the Company with a proprietary and unique window into the intracellular action of CNS d...

Quark Pharmaceuticals Announces Dosing of the First Patient in Phase I/II Clinical Trial for Systemically Delivered siRNA Drug Candidate for Delayed Graft Function

... expression of p53 to protect normal cells from acute injury. QPI-1002 is a chemically modified siRNA discovered by Quark with structure covered under licenses fr...523655 (RTP801i-14), currently in Phase II clinical trials, is a synthetic, chemically modified siRNA designed to inhibit the expression of the gene RTP801 discov...
Chemically in Medical Products

Restylane® Hyaluronic Acid Dermal Filler

Description:... Restylane is a gel of hyaluronic acid generated by Streptococcus species of bacteria, chemically crosslinked with BDDE, stabilized and suspended in phosphate buffered saline at pH = 7 and concentration of 20 mg/mL. Restylane is free of animal prot...
Company:Medicis Aesthetics, Inc.

Eppendorf Reference Series 2000 Fixed-volume Pipette, 1,000 l

Description:... system ensures utmost accuracy and precision. Ejection sleeve can be removed to fit into smaller vessels. Smooth-running piston is corrosion-free and chemically resistant . UV-resistant and completely autoclavable without any impairment of accuracy or precision....
Company:Eppendorf North America

Eppendorf Reference Series 2000 Fixed-volume Pipette, 200 l

Description:... system ensures utmost accuracy and precision. Ejection sleeve can be removed to fit into smaller vessels. Smooth-running piston is corrosion-free and chemically resistant . UV-resistant and completely autoclavable without any impairment of accuracy or precision....
Company:Eppendorf North America

Eppendorf Reference Series 2000 Fixed-volume Pipette, 100 l

Description:... system ensures utmost accuracy and precision. Ejection sleeve can be removed to fit into smaller vessels. Smooth-running piston is corrosion-free and chemically resistant . UV-resistant and completely autoclavable without any impairment of accuracy or precision....
Company:Eppendorf North America

Eppendorf Reference Series 2000 Fixed-volume Pipette, 20 l

Description:... system ensures utmost accuracy and precision. Ejection sleeve can be removed to fit into smaller vessels. Smooth-running piston is corrosion-free and chemically resistant . UV-resistant and completely autoclavable without any impairment of accuracy or precision....
Company:Eppendorf North America

Eppendorf Reference Series 2000 Fixed-volume Pipette, 2,000 l

Description:... system ensures utmost accuracy and precision. Ejection sleeve can be removed to fit into smaller vessels. Smooth-running piston is corrosion-free and chemically resistant . UV-resistant and completely autoclavable without any impairment of accuracy or precision....
Company:Eppendorf North America
Chemically in Medical Dictionary

Zinc

...s a metallic chemical element with the symbol Zn and atomic number 30. It is a first-row transition metal in group 12 of the periodic table. Zinc is chemically similar to magnesium because its ion is of similar size and its only common oxidation state is +2. Zinc ... Zinc is an essential mineral that i...

Vitamin K

...ipophilic, hydrophobic vitamins that are needed for the posttranslational modification of certain proteins, mostly required for blood coagulation. chemically they are 2-methyl-1,4-naphthoquinone... A vitamin is an organic compound required as a nutrient in tiny amounts by an organism. A compound is ...

Radon

... ENTRY INTO BUILDINGS. MITIGATION STRATEGIES. HEALTH ... GUIDELINES FOR MITIGATING HIGH LEVELS OF RADON IN THE HOME. EPA RECOMMENDATIONS ... ... chemically inert, but radioactive, radon is the heaviest noble ... standard temperature and pressure radon is a colorless gas ... Radon clathrates have a...

Metabolism

...olism and slow thyroid in article ... I hear the word " metabolism " nearly every day. ... METABOLISM IS THE STUDY OF WHAT LIVING ORGANISMS ARE chemically AND HOW THEY USE ... Consider the efficiencies of energy metabolism in the same light as you would ... Metabolism . Metabolism ... Metab...

Melatonin

... Melatonin ), also known chemically as N-acetyl-5-methoxytryptamine, is a naturally occurring hormone found in animals and in some other living organisms, including algae. Circulating ...

Immunofluorescence

... of biomolecules of interest. Immunofluorescent-labeled tissue sections... immunofluorescence n. Any of various techniques that use antibodies chemically linked to a fluorescent dye to identify or quantify antigens in a ... immunofluorescence ... Double Immunofluorescence stain (Giorgio Cattoret...
Chemically in Biological News

Engineers develop method to disperse chemically modified graphene in organic solvents

AUSTIN, Texas A method for creating dispersed and chemically modified graphene sheets in a wide variety of organic solvents has been developed by a University of Texas at Austin engineering team led by Professor Rod Ruoff, opening the door to use graphene in a host of important materials and appl...

NYU and MSKCC research provides model for understanding chemically induced cancer initiation

A team from the chemistry and biology departments of New York University, in collaboration with Memorial Sloan Kettering Cancer Center (MSKCC), has uncovered a conformational switch--a change in shape in a carcinogen-damaged DNA site--in tumor suppressor genes altered by a known cancer-causing chem...

Navigating in the ocean of molecules

...old. This generates innumerable parent-child relationships - structurally related molecules of varying complexity. The advantage lies in the fact that chemically similar compounds are very likely to display similar biological activity. "These structurally-based lineages form the branches of the tree," explai...

AGU journal highlights -- Aug. 6, 2009

... observations. Through providing a new way to compare geodynamic and seismic Earth models quantitatively, the authors suggest that the mantle could be chemically homogeneous but thermally differentiated because of a large heat flux from the core. This implies that thermal history models of the Earth may have to...

Researchers design first model motor nerve system that's insulated and organized like the human body

...ioengineer at UCF and the lead researcher on this project explained: "The nodes of Ranvier act like power station relays along the myelin sheath. They chemically boost signals, allowing them to get across breaks in myelin, or from node to node, at the electrically charged nodes of Ranvier. Nerve malfunctions, ...

PNNL scientist garners early career presidential award

...d motion; so too do fluids meander through the subsurface. Down below, the fluids made of gases and liquids -- air and water, for example -- react chemically with rocks and bacteria. Modeling that activity allows researchers to trap contaminants and in some cases transform them into harmless minerals. Simil...
Chemically in Biological Technology

New clues about a hydrogen fuel catalyst

...mbined experimental and theoretical studies to identify the characteristics of the catalyst, a cluster of rhodium, boron and other atoms. The catalyst chemically reacts with ammonia borane, a molecule that stores hydrogen densely, to release the hydrogen as a gas. Their results, which reveal many molecular deta...

Rapid heating prepares energy-saving zeolite for greater role in industrial separations

...als during operation of the membrane," says Snyder, who worked with Tsapatsis as a postdoctoral researcher. "In short, this type of heat treatment may chemically glue the crystal domains together." A second round of RTP or conventional slow-heating is then necessary, says Snyder, to completely remove the SDA...

SAFC Biosciences(R) Defines Hydrolysate Components That Enhance Chinese Hamster Ovary (CHO) Cell Line Protein Production

...AL ), announced today that it has developed a new, chemically defined cell culture supplement based on the chara... , a synthetically produced animal-component free, chemically defined alternative to undefined hydrolysates, has...nabled SAFC Biosciences to develop the first known chemically defined hydrolysate replacement. Matt Caple, SAFC ...

Nuevolution Announces Worldwide Technology Cross-Licensing Agreement With GSK

...technologies for rapid synthesis and DNA-tagging of hundreds of millions of chemically diverse drug-like small molecule compounds and the efficient screening of t...etics(R) enables rapid synthesis and DNA-tagging of hundreds of millions of chemically diverse drug-like small molecule compounds and the efficient screening of t...

UCSF researchers help crack parasite genome, identify drug leads

...nue the life cycle. "It's a wonderfully evolved pathogen," Caffrey said, noting the intricate parasite biology. The Sandler Center's mission is to chemically interrupt parasite development in humans and alleviate the significant morbidity associated with the disease. "Research with the schistosome worm ...

Clavis Pharma Raises NOK 129 Million (USD 20 Million) in a Private Placement to Fund Further Development of its Pipeline of Novel Anticancer Drug Candidates

...chnology (LVT) platform to create New Chemical Entities (NCEs), by significantly improving already established drugs. The improvements are achieved by chemically binding specific unsaturated lipids to existing, and well understood, approved pharmaceuticals. Data generated suggests the resulting patentable NCEs ...
Chemically in Biological Products

BL21 Star (DE3) One Shot Chemically Competent E. coli from Invitrogen

Description: BL21 Star strains are high-performance BL21 hosts designed for improved protein yield in T7 promoter-based expression systems (Figure 1). Because the T7 RNA polymerase synthesizes mRNA more rapidly than E. coli RNA polymerases transcription from the T7 p...
Company:Invitrogen

CopyControl cDNA, Gene and PCR Cloning Kit w/ Chemically Competent E. coli cells from EPICENTRE Biotechnologies

Description: The CopyControl™ PCR Cloning Kits are designed to speed up the PCR cloning process and to ensure that all PCR products, regardless of sequence or type of polymerase used, are efficiently cloned. All PCR products including those that are difficult to clone by other PCR cloning methods or that m...
Company:EPICENTRE Biotechnologies

One Shot INVAlphaF' Chemically Competent E. coli from Invitrogen

Description: Request Info...
Company:Invitrogen

GIBCO Chemically Defined Lipid Concentrate from Invitrogen

Description: Chemically Defined Lipid Concentrate...
Company:Invitrogen

Zero Blunt TOPO PCR Cloning Kit with One Shot Mach1 T1 Phage-Resistant Chemically Competent E. coli from Invitrogen

Description: The Zero Blunt TOPO PCR Cloning Kit offers the fastest and easiest method for high-efficiency (>=95%) cloning of blunt-end PCR products amplified with proofreading thermostable polymerases. The kit includes the linearized and topoisomerase I-activated pCR-Blunt II-TOPO vector for 5-minute bench-top...
Company:Invitrogen

Zero Blunt TOPO Kit for Sequencing with One Shot Mach1 T1 Phage-Resistant Chemically Competent E. coli from Invitrogen

Description: The TOPO Cloning Kits for Sequencing allow 5-minute cloning and subsequent sequencing of PCR products. The kits contain TOPO Cloning vectors with primer sites located as close as 33 base pairs from the PCR product insertion site. This minimizes the amount of vector DNA that needs to be read before ...
Company:Invitrogen

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Chemically in Biological Definition

Active site

...sence of another molecule. There are three primary modes of inhibition. In competitive inhibition , the active site itself is blocked when a molecule chemically similar to the substrate binds to the active site but cannot be processed by the enzyme. In noncompetitive inhibition , the inhibitor binds to the en...

Blood

...d in blood is directly proportional to the PO2 of the blood. The hemoglobin molecule is the primary transporter of oxygen. 98.5% of the oxygen is chemically combined with the Hb . Only 1.5% is physically dissolved. Transport of carbon dioxide When systemic arterial blood flows through capillaries, ...

Chemiosmotic hypothesis

...at the time, and not well accepted. The prevailing view was that the energy of electron transfer was stored as a stable high potential intermediate, a chemically more conservative concept. The problem with the older paradigm is that no high energy intermediate was ever found, and the evidence for proton pumpi...

Digestion

...the process whereby a biological entity processes a substance, in order to chemically convert the substance into nutrients . Digestion occurs at the multicell...nivorous plants capture other organisms, usually invertebrate animals, and chemically digest them. Fungi also are very effective at digesting organic material....

DNA

... Each vine-like molecule is a strand of DNA: a chemically linked chain of nucleotides , each of which consi...polymerase . The unwinding requires that helicases chemically cleave the phosphate backbone of one of the strand...nd Crick restricted themselves to what they saw as chemically and biologically reasonable. Still, the breadth of...

Glucose

... eventually form carbon dioxide and water , yielding energy, mostly in the form of ATP . It is also broken down from polysaccharides before use. chemically joined together, glucose and fructose form sucrose . Starch , cellulose , and glycogen are common glucose polymers ( polysaccharides ). The ...
Chemically in Biological Dictionary

Transcapsidation

...her ... would be viral transmission ( transcapsidation ), since a virus could spread ... Radioactive fallout produces various metal ions that are chemically and ... would be viral transmission ( transcapsidation ), since a virus could spread ... ISB To Discontinue 1-800 Service. Progress In Developing...

Taq polymerase

...nt Taq DNA Polymerase :EUR0.01/Unit!Order your free sample today!Bulk order,please contact us.Email:master@shinegene .org.cn Fastest to activate chemically modified hot start Taq DNA polymerase . ... 5-6 - Taq DNA Polymerase (temperature-dependent inhibitor), Vendor B ... Taq DNA Polymerase ...

Subcloning

... Subcloning Service. Subcloning is easier when someone else does it. ... Our subcloning strategies may include any of the following steps: ... chemically competent <I>E. coli</I> cells suitable for subcloning efficiency transformation in a wide variety of applications.<br/>&l...

Single locus probe

...... analysis performed using 1 single - locus probe . ... Figure 1-3—Detailed Schematic of Single - locus Probe RFLP Analysis. Intact DNA is chemically ... Single - locus Probe Analysis. Several acceptable protocols exist to determine ... bridizing with a single - locus probe involves iden-...

Palindromic Sequence

...ears. ... of the patterns in the sequence of palindromic years (1551, 1661, 1771, 1881, ... To sequence the palindromic junctions, we first chemically modified the DNA with ... A) Sequence analysis of a palindromic junction: The native sequence prior to DNA ... palindromes, we developed a me...

Myofibrils

...rsely cut cells. ... Spontaneous oscillation of tension and sarcomere length in skeletal myofibrils . ... Single myofibrils were isolated from chemically skinned rabbit heart and mounted ... Myofibrils were prepared as described (24) with careful attention paid to the ... We measured the ATPase a...
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