BRCA1 causes ovarian cancer through indirect, biochemical route
Mutated BRCA1 genes cause ovarian cancer indirectly, by interfering with the biochemical signals one ovarian cell sends to another, according to a team of researchers led by scientists at the USC/Norris Comprehensive Cancer Center and the Keck School of Medicine of the University of Southern California. Their work is being published in the March 29 issue of the journal Current Biology.</p...Study shows nanoshells ideal as chemical nanosensors
'Nanoshells' enhance sensitivity to chemicaldetection by factor of 10 billionNew research published in the Proceedings of the National Academy ofScience finds that tailored nanoparticles known as nanoshells canenhance chemical sensing by as much as 10 billion times. That makesthem about 10,000 times more effective at Raman scattering thantraditional methods. Whenmolecules and materi...MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks
Dr. Roger Brent, President and Director of Research at the the release of a new approach to simulation of intracellularbiochemical networks in the January 2005 edition of NatureBiotechnology.The research article, entit...Researchers discover chemical compounds that affect plant growth
A team of biologists from the University of California, Riverside has used chemical genomics to identify novel compounds that affect the ability of plants to alter their direction of growth in response to gravity, a phenomenon known as gravitropism. The researchers screened a library of 10,000 small molecules, the practice is known as chemical genomics, to identify those that could positiv...Chemicals in tattoo inks need closer scrutiny
As tattoos have grown in popularity, so have complaints of adverse side effects associated with both their application and removal. A new study, done by chemistry students at Northern Arizona University, looked at the chemical composition of a variety of tattoo inks to better understand their potential health risks. The findings, presented today at the 229th national meeting of the Americ...15(S)-HEDE from Cayman Chemical
Description:15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC50 value of 26 µM....15(S)-15-methyl Prostaglandin F2alpha from Cayman Chemical
Description:15(S)-15-methyl PGF2α is a metabolically stable analog of PGF2α. It is a potent uterine stimulant and abortifacient which can be administered intramuscularly to induce labor. It induces luteolysis and reduces serum progesterone concentrations when given as an intramuscular injection in non-pregnant rhesus monkeys....S. cerevisiae Direct Transformation Kit from Wako Chemicals USA, Inc.
Description:This kit is designed for easy transformation of the budding yeast, Saccharoyces sp.. The protocol allows for successful transformation simply by mixing a plasmid DNA and the kit reagents with cultured yeast cells. No complicated steps, such as centrifugation or cell washing, are required. The kit is particularly well suited for high-throughput transformation of a large number of yeast strains gro...S. cerevisiae Direct Transformation Kit from Wako Chemicals USA, Inc.
Description:This kit is designed for easy transformation of the budding yeast, Saccharoyces sp.. The protocol allows for successful transformation simply by mixing a plasmid DNA and the kit reagents with cultured yeast cells. No complicated steps, such as centrifugation or cell washing, are required. The kit is particularly well suited for high-throughput transformation of a large number of yeast strains gro...Rainbow trout Vitellogenin EIA Kit from Cayman Chemical
Description:Detection of the yolk protein Vtg in plasma from juvenile or male fish is a simple and sensitive biomarker for endocrine disrupting chemicals (EDCs) with estrogenic effects in fish. Quantification of Vtg has become an accepted screening test for the estrogenic effects of EDCs in fish. The Vtg (rainbow trout) EIA kit is a double-antibody immunometric (sandwich) EIA for analyzing Vtg in plasma samp...Chemical Stability of Disposables
Disposables such as Eppendorf Tubes and pipette tips are frequently exposed to chemical reactions and they must withstand the various kinds of stress and strain encountered in everyday laboratory work (such as centrifuging and autoclaving). The stability level of these products is largely determined by the materials fr...Chemical Stability of the Brinkmann Bottletop Dispenser and the Brinkmann Bottletop Buret
Bottletop Dispenser and the Brinkmann Bottletop Buret Bottletop dispensers are used in the lab for dispensing a wide range of different solvents from glass or stainless steel containers. These dispensers have to meet various requirements. For example, they must not give...Efficient Delivery of siRNAs to Human Primary Cells: Electroporation vs. Chemical Transfection
(Research Associate II, Ambion, Inc.) Gene silencing using small interfering RNAs (siRNAs) has become a powerful method for studying gene function. Human primary cells are often desired for such experiments because they are mor...Optimizing Chemical Transfection and Electroporation of siRNAs
(Associate Scientist, Ambion, Inc.) (Vice President and CSO, Cyto Pulse Sciences, Inc.) Low transfection efficiency is the most frequent cause of unsuccessful gene silencing...Unique Histochemical Substrate Permits Dual Staining In Animal Tissue
Daniel G. Flowers and Lloyd A. Culp, Ph.D....Chemical in Gila monster's saliva yields Alzheimer drug
Alzheimer's is a degenerative brain disease that usually begins gradually, causing a person to forget recent events or familiar tasks. The disease eventually leads// to confusion, personality and behavior changes and impaired judgment. Communication becomes more difficult as the disease progresses, leaving those affected struggling to find words, finish thoughts or follow directions. Eventually,...Biochemical Markers Might Help Predict Heart Problems
Damage to the heart is one of the most worrisome long-term side effects of high-dose chemotherapy, say specialists. Hence they feel the // need to identify biochemical markers that might indicate which patients are at greatest risk and how severe their heart disease might be. Troponin I is a protein present only in heart cells. TNI blood concentration is a well-established marker of hea...Chemical found in plants may be the treatment for leukemia
Research has found out that a chemical called parthenolide is successful in destroying stem cell leukemia. The chemical is found// in a widely available plant of North America, called feverfew. This plant has been used for centuries to treat migraine and rheumatoid arthritis, but this is the first time this is being linked to blood cancer research. Past studies have found that malignan...Chemicals in clear plastics can cause learning difficulties
In a recent study that came out in the journal Environmental Health Perspectives had brought out the// detrimental effects of clear plastics on human beings. Bisphenol-A (BPA) is a chemical founding the clear plastics that are used as food grade materials for making air tight containers, drinking water bottles, even feeding bottles for infants. The scientists from Yale School of Medic...Harmful chemicals change the genetic response to hormone estrogen
The drug diethylstilbestrol (DES) may lead to different genetic response// to the female hormone estrogen, when exposed to it early in life. The drug DES was prescribed to women for prevention of miscarriages, from the year 1938 to 1971. Research says that daughters of women who had used the drug are at increased risk from reproductive tract abnormalities, ectopic pregnancy, pre-term d...Acid / Corrosive Chemicals Storage Cabinet
Description:SCE offers a full line of cleanroom-safe polypropylene cabinets for today's most demanding manufacturing and laboratory environments. Every SCE product stands up to the most stringent cleanroom / safety requirements. Now you can have years of clean, safe storage of your hazardous acid / corrosive chemicals and materials with out the rusting due to metal construction or the delaminating of wood co...Flammable Chemical Storage Cabinets
Description:Inquire...Flammable Chemical Storage Cabinets, Justrite Model J25452
Description:Inquire...Chemically Resistant Sealing Mat for 384-well Plate
Description:Chemically Resistant Sealing Mat for 384ch, Square Well Available Sterile...Chemically Resistant Sealing Mat for 96-well Deep Well Plate
Description:Chemically Resistant Sealing Mat for 96ch, 1.1ml or 2.0ml, Deep Well, Round Available Sterile...Malvern initiates European user group meetings for chemical imaging
WORCESTERSHIRE , England, 21 June 2007, Malvern Instruments hasheld the inaugural meeting in Europe for users of the company'snear infrared chemical imaging (NIR-CI) systems. The one-day event,which took place on 13 June 2007 was hosted by AstraZeneca inMacclesfield, UK. Malvern customers from some of the world's majorpharmaceutical companies joined Malvern's technical and scientificteam...