FDA Approves New 3000 IU Vial Size for Kogenate(R) FS, antihemophilic factor (recombinant)
...emophilia A, the most common type of hemophilia, is caused by deficient or defective blood coagulation proteins, known as factor VIII. Hemophilia A is characterized
by prolonged or spontaneous bleeding, especially into the muscles, joints, or internal organs. Approximately one in 5,000 males born in the United St...
Carnegie Mellon develops innovative method to detect genetic causes of complex diseases
...to complex disease syndromes such as diabetes, asthma and cancer, which are characterized
by multiple clinical and molecular traits.
Rather than searching one at a...n networks of genes and clinical traits."
Severe asthma, for instance, is characterized
by more than 50 clinical traits, some related to environment or activity le...
Bacteria May Be Connected to Colic
Researchers found the bacterium Klebsiella along with gut inflammation in the intestines of all babies in their study who had colic, a condition characterized
by uncontrollable crying.
"We believe that the bacterium may be sparking an inflammatory reaction, causing the gut inflammation," Dr. J. Marc Rho...
Orexigen(R) Therapeutics Announces Second Quarter 2009 Financial Results
...tic to delay or prevent regulatory approval or commercialization, or result in product liability claims, including serious adverse events that are not characterized
by clinical investigators as possibly related to Contrave; the third parties on whom Orexigen relies to assist with the development programs for Contr...
IPC The Hospitalist Company Reports Second Quarter 2009 Results
...Guidance" regarding projected operating results, revenues, earnings, and IPC's growth opportunities and strategy. Forward-looking statements are often characterized
by terminology such as "believe", "hope", "may", "anticipate", "should", "intend", "plan", "will", "expect", "estimate", "project", "positioned", "str...
Lexicon Initiates Phase 2 Clinical Trial of LX2931 in Patients With Rheumatoid Arthritis
... which the immune system malfunctions and causes the body to attack its own organs, tissues and cells. Rheumatoid arthritis is an autoimmune disorder characterized
by stiffness, pain, swelling, and limitation of motion in multiple joints. More than 2 million Americans suffer from rheumatoid arthritis, which, if ...
Characterized in Medical Technology
Labopharm files New Drug Submission with Health Canada for novel antidepressant
...2009 issue of Psychiatry (Edgemont) (Volume 6, Number 5) ( www.psychiatrymmc.com ).
Major depressive disorder (MDD) is a common mental illness often characterized
by a combination of symptoms that interfere with a person's ability to work, sleep, study, eat, and enjoy once-pleasurable activities. Approximately 8...
Telik Announces Publication of Positive Phase 1 Results of a Multicenter Study of Ezatiostat Hydrochloride (TELINTRA(R), TLK199) Tablets In Patients With Myelodysplastic Syndrome
... from Telik.
Background on MDS and TELINTRA
MDS is a heterogeneous group of blood stem cell disorders of increasing incidence. MDS is characterized
by ineffective blood cell production involving one or more of the red cell, white cell or platelet lineages and with MDS patients having a variable ri...
FDA Advisory Committee Votes in Favor of SAPHRIS(R) (asenapine) for Acute Bipolar I Disorder and Acute Schizophrenia
Schizophrenia is a chronic, disabling brain disorder that is characterized
by hallucinations, delusions and disordered thinking. The condition affect... I disorder (also known as manic depression) is a chronic, episodic illness characterized
by mania (episodes of elevated moods, extreme irritability, decreased sleep...
Wyeth Reports Publication of Phase 3 Data for Bazedoxifene/Conjugated Estrogens, an Investigational Compound Being Studied for the Treatment of Menopausal Symptoms
... with conjugated estrogens, may have the potential to eliminate the need for progestin in menopausal therapy in women with an intact uterus. BZA/CE is characterized
by Wyeth as a TSEC (tissue selective estrogen complex) as it combines a selective estrogen receptor modulator (SERM) with conjugated estrogens.
Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology
...gy company developing a new, fully human monoclonal antibody platform based on transgenic rats. The rat is a widely used laboratory animal with a well characterized
immune system, a nearly complete genome sequence, and established transgenesis and hybridoma technologies. OMT's antibody platform is the result of a...
Schering-Plough Announces U.S. Filing of Mometasone Furoate/Formoterol Fumarate Combination for the Maintenance Treatment of Asthma
...ompany is based in Kenilworth, N.J., and its Web site is www.schering-plough.com .
Asthma is a chronic lung disease characterized
by inflammation of the air passages, resulting in the temporary narrowing of the airways that transport air from the nose and mouth to the lungs.(2) A...
Characterized in Medical Products
Brooks Brothers Ophthalmic Collection
Description:... The license agreement between Brook Brothers and Luxottica Group dates back to 1993. characterized
by lightweight materials and a slender line, the Brooks Brothers collections reflect the unique features of the style of this American brand. A produc...
Description:... movie and show business celebrities since day one, Ray-Bans styles are sunglasses par excellence and by far the best-selling sunglasses in the world. characterized
by high quality lenses and materials as well as cleancut, never excessive design and style, these sunglasses are suited to the different facial featur...
Dolce & Gabbana Ophthalmic Collection
Description:...by Luxottica drew its inspiration from the fascinating 60s and 70s. This collection brings the periods shapes up to date and highlights its materials, characterized
by precious details such as logos in Swarovski crystals or elegant metal circles....
ImmunoDOT Thyroid Autoimmunity Test
Description:...e (microsome) in serum and heparinized whole blood and is used as an aid in the diagnosis of thyroid disorders. Autoimmune thyroid gland disorders are characterized
by detection of anti-thyroid antibodies, primarily against thyroglobulin and/or
microsomal thyroid antigens....
SHBG IRMA Test
Description:...presumably bioactive, testosterone concentrations, and as a result a free testosterone index based on the ratio of total testosterone to SHBG has been characterized
Hammond GF. Endocrin Rev 11:65-79, 1990.
Rosner W. Endocrin Rev 11:80-91, 1990.
Mathur RS, et al. Fertil Steril 35:29-35, 1981....
Company:Diagnostic Systems Laboratories, Inc.
Osteocalcin IRMA Test
Description:...active fragments that are rapidly metabolized in the kidney and, to a lesser extent, in the liver . Serum osteocalcin is elevated in disease states characterized
by increased bone turnover such as renal osteodystrophy, osteoporosis, hyperparathyroidism and Pagets disease, and low in conditions associated with l...
Company:Diagnostic Systems Laboratories, Inc.
Characterized in Medical Definition
... genetic disorder in which there is absence of transferrin , a plasma protein that transports iron through the blood .
Atransferrinemia is characterized
by anemia and hemosiderosis in the heart and liver . The iron damage to the heart can lead to heart failure . The anemia is typically microcy...
High Frequency Ventilation
... type has its own unique advantages and disadvantages. The types of HFV are characterized
by the delivery system and the type of exhalation phase.
High Frequency V...cillatory Ventilation (HFOV)
High Frequency Oscillatory Ventilation is characterized
by very high respiratory rates about 15 hertz (900 breaths per minute) an...
...first-person subjective experience (Price, Adams & Coyle, 2000). This antipodal distinction between brain and mind as two different entities has characterized
many of the differences between the two specialties. However, it is argued that this division is simply not veridical; a plethora of evidence from the...
...abeled "The Infamous Decade". In it, Carrillo witnessed what has been described as the "systematic sacking and destruction of his fatherland, a period characterized
by the leaders' deep moral decadence, in which self-imposed corruption, economic felonies, the selling out of the national patrimony, and the impoveri...
...s not yet gained universal acceptance. Both terms are unable to capture the nature of this unique form of the Bipolar Disorder.
Ultradian cycling is characterized
by more than four mood states within a year. Often these mood states occur within the space of a few weeks or even a single day. These oscillations, c...
Characterized in Medical Dictionary
... is also more likely to develop in persons who are ... Glaucoma is a group of disorders leading to progressive damage to the optic nerve, and is characterized
by loss of nerve tissue resulting in loss of vision. Glaucoma . Alternative Names Return to top ... Angle-closure (acute) glaucoma occurs w...
..... Overview: Zollinger - Ellison syndrome (ZES) is a rare condition characterized
by ... The syndrome was originally described by Zollinger and Ellison ... occur at any age, people ... Zollinger - Ellison Syndrome (ZES) is characterized
by excessive production of ... syndrome , zollinger - ellison , disorders...
... Herpes zoster , commonly known as shingles, is a viral disease characterized
by a painful skin rash with blisters in a limited area on one side of the body, often in a stripe. The initial infection with varicella zoste...
...ognosis. Xanthoma symptoms, causes, diagnosis, and treatment information for Xanthoma ... Xanthoma : A benign fibrohistiocytic neoplasm characterized
by a localized ... Xanthoma - Overview, Xanthoma is a skin condition in which fat builds up under the surface of the skin. ... Definition ...
...ng Cough ) – What You Need To Know. Brief description ... Parents: Protect Yourself and Your Children from Whooping Cough (Flyer) (exit) ... characterized
by severe coughing spells, whooping cough is a respiratory system illness caused by bacteria. This eMedTV article provides an overview of whoop...
..... Information about weakness in the free online English dictionary and encyclopedia. ... inanition, slackness, lethargy, lassitude - weakness characterized
by a lack of ... Do you really think it is weakness that yields to temptation? ... If America shows uncertainty and weakness in this decade, t...
Characterized in Biological News
Early stage colon cancer characterized by inactivation of gatekeeper gene
The absence or inactivation of the RUNX3 gatekeeper gene paves the way for the growth and development of colon cancer, Singapore scientists report in the Sept. issue of the journal Cancer Cell . Previous studies have shown that RUNX3 plays a role in gastric, breast, lung and bladder cancers.
Mechanisms of plant-fungi symbiosis characterized by DOE Joint Genome Institute
WALNUT CREEK, CA, Plants gained their ancestral toehold on dry land with considerable help from their fungal friends. Now, millennia later, that partnership is being exploited as a strategy to bolster biomass production for next generation biofuels. The genetic mechanism of this kind of symbiosis,...
Ovarian cancer stem cells identified, characterized
Researchers at Yale School of Medicine have identified, characterized
and cloned ovarian cancer stem cells and have shown that these stem cells may be the source of ovarian cancers recurrence and its resistance to chemotherapy.
These results bring us closer to more effective and targeted treat...
La Jolla Institute discovers novel tumor suppressor
...sor that may be important in myeloproliferative diseases and some types of lymphoma and leukemia. Myeloproliferative diseases are a group of disorders characterized
by an overproduction of blood cells by the bone marrow and include chronic myeloid leukemia. Lymphoma and leukemia are cancers of the blood.
August 2009 Geology and GSA Today media highlights
...nds around the northern boundary of China and the deserts on the northern margin of the Tibetan Plateau. However, the modern spring dust in Beijing is characterized
by totally different isotopic compositions, which indicate an additional contribution (about 50%) from the desertified lands in its adjacent north and...
Antibody targeting of glioblastoma shows promise in preclinical tests, say Lombardi researchers
...r cells, and they eventually reported on PTN in 1992. He and his colleagues spent the next years finding PTN's receptor, which is ALK. They have since characterized
the relationship between PTN and ALK, reporting in this study that many brain cancers overexpress PTN and ALK very similar to the developing brain. "W...
Characterized in Biological Technology
Receptor Binding Assays using Fluorescence Polarization Detection: the [FP]2TM Characterized Tracers
A. Gagne, E. Robitaille, M. Harvey, J.-A. St. Pierre, D. Wenham and P. Banks
High throughput screening is an indispensable tool for modern drug discovery 1-3 . The process is typically highly automated and can provide screening rates over 100,000 sample...
Synthetech Reports First Quarter Fiscal 2010 Results
... in large-scale customer projects and the timing of shipments arising from these projects. Synthetech operates in a challenging business environment, characterized
by the unpredictable dynamics and life cycle of pharmaceutical projects, which can lead to rapid fluctuations in the mix of projects and revenues. As...
Transposagen Creates a Rat Model of the Human Immune System
... the Medical College of Wisconsin have created and characterized
the world's first rat model of severe combined imm...nology companies. "Transposagen is pleased to have characterized
the world's first rat model of SCID. We now have i...development research. Transposagen's SCID rats are characterized
by a deficiency of T-cells, B-cells and NK-cells, ...
DOR BioPharma Receives FDA Orphan Drug Designation for orBec(R) for the Treatment of Chronic Gastrointestinal GVHD
...ouble-blind, placebo-controlled trial in the prevention of acute GVHD. Oral BDP may also have application in treating other gastrointestinal disorders characterized
by severe inflammation. Additionally, DOR has a Lipid Polymer Micelle (LPM(TM)) drug delivery technology for the oral delivery of leuprolide for the t...
Five Questions About Protopic (tacrolimus) Ointment
CHICAGO, Aug. 3 /PRNewswire/ -- Known medically as atopic dermatitis (AD), eczema is characterized
by dry, itchy skin and rashes.(1) Scratching the affected area of skin may result in redness, swelling, scaling, cracking, weeping of clear fluid, an...
SmartGene's Services for Faster, More Precise Identification of Bacteria and Fungi to be Used by The Johns Hopkins Hospital
... dendrograms and reports. DNA sequences are interrogated using SmartGene's broad, constantly updated reference databases, which take account of newly characterized
and emerging pathogens. SmartGene's technology allows its customers to manage and more fully utilize their genetic sequence data over time, completely...
Characterized in Biological Products
QXL 520 C2 maleimide from AnaSpec
Description:.... References: Evans NA, et al. (2001). Visualizing differences in ligand-induced beta-arrestin-GFP interactions and trafficking between three recently characterized
G protein-coupled receptors. J Neurochem 77, 476-85; Nasarabadi S, et al. (1999). Simultaneous detection of TaqMan probes containing FAM and TAMRA rep...
Rabbit Anti-Kv4.2 Polyclonal Antibody, Unconjugated from GeneTex
Description:...potential. Potassium channels are encoded by numerous genes whose products can be classified into distinct subfamilies of which the most distinctively characterized
is that of the Kv1 shaker class....
Rabbit Anti-JNK1, phospho (Thr183 / Tyr185) Polyclonal Antibody, Unconjugated from GeneTex
Description:... from survival, cell proliferation, and apoptosis. The MAPKs family is also characterized
by their requirement for dual phosphorylation at a conserved threonine and ...activation. The closely related ERK1 (44 kDa) and ERK2 (42 kDa) kinases are characterized
by their requirement for dual phosphorylation at a conserved T-E-Y motif. W...
Rabbit Anti-NPY Y2 Receptor Polyclonal Antibody, Unconjugated from GeneTex
Description:... Rabbit polyclonal NPY Y2 Receptor antiserum This NPY Y2 antibody has been extensively characterized
at the spinal level and is currently being characerized in brain. The antibody has been tested in both rat and mouse and appears to work better on mos...
Expand High Fidelity PLUS PCR System; Thermostable DNA polymerase mixture from Roche Applied Science
Description:...he first product of a family of next-generation PCR Blends. This new blend combines Taq DNA Polymerase with a novel proofreading protein isolated and characterized
by Roche Applied Science. This protein mediates proofreading activity, but has no polymerase activity itself. The synergy between the mechanism of the...
Company:Roche Applied Science
AmpliTaq DNA Polymerase, 1,000 units with Buffer I from Applied Biosystems
Description:... AmpliTaq DNA Polymerase is the most thoroughly characterized
enzyme available for the PCR process, a testimony to its overall utility an...us aquaticus Taq DNA polymerase gene in E. coli.1 It is the most thoroughly characterized
enzyme available for the polymerase chain reaction (PCR) process and its re...
Characterized in Biological Definition
... Anabolism is the aspect of metabolism that is characterized
by growth. One way of categorizing metabolic processes, whether at the cellular , organ or organism level is as anabolic or catabolic .
... AI research began early in the history of digital computers, and was often characterized
in those years by a "top-down" approach based on complicated networks of ru...his phenomenon, but it could be something as simple as..."
The field is characterized
by the extensive use of computer programs and computer simulations whic...
... it does not usually describe biological systems in terms of objects which obey immutable physical laws described by mathematics , it is nevertheless characterized
by several major principles and concepts which include: universality, evolution, diversity, continuity, homeostasis and interactions.
...ause tetanus , typhoid fever , pneumonia , syphilis , cholera , foodborne illness and tuberculosis . Sepsis , a systemic infectious syndrome characterized
by shock and massive vasodilation, or localized infection, can be caused by bacteria such as streptococcus , staphylococcus , or many gram-negative ...
...eer, first used the word biotechnology
1975 Method for producing monoclonal antibody developed by Kohler and Milstein
1980 Modern biotech is characterized
by recombinant DNA technology . The prokaryote model, E. coli , is used to produce insulin and other medicine, in human form. (About 5% of diab...
...the genetic code
Max Perutz & John Kendrew , pioneers of protein crystallography
Other notable biophysicists
Howard Berg , characterized
properties of bacterial chemotaxis
Friedrich Dessauer , research on radiation, especially X-rays
Characterized in Biological Dictionary
...ein-coding), zona pellucida glycoprotein 2 (sperm receptor) ... Recommended Name: Zona pellucida sperm-binding protein 2 ... Type D was characterized
by a relatively smooth exterior of the zona pellucida ." Below are photomicrographs of these types of zona pellucida . ... The binding of spe...
...aries Venules Veins Vena cava Heart. Pulmonary circulation ... High endothelial venules (HEV) are specialized post-capillary venous swellings characterized
by simple cuboidal cells as opposed to simple Squamous cells found in regular venules . HEVs enable lymphocytes circulating in the blood to dir...
...... interaction detection between two unlinked loci have advantages, as follows. ... First, since interaction between two unlinked loci can be characterized
by LD ... The need to use the unlinked anonymous technique for surveillance of HIV was ... Unlinked anonymous surveys in the United Kingdom sta...
...this unicellular organism, "development" is controlled at both the ... Prokaryote, relatively simple unicellular organism, such as a bacterium, characterized
by the absence of a nucleus and other specialized cell... Scientists discover microRNAs in the unicellular green alga, Chlamydomonas reinhardti...
Transcription start site
...start site analysis of human genes in ... DBTSS: database of transcription start sites , progress report 2008. Nucleic Acids Res. ... ... characterized
the static structures of transcription start site usage within ... and demonstrate that start site selection within many mouse core prom...
...lood disorders with symptoms ... Beta thalassemias . Who is at risk for thalassemias ? ... Thalassemia describes a group of inherited disorders characterized
by reduced or ... Beta thalassemia causes variable anemia that can range from moderate to severe, ... ...