Channel

Sodium channel blocker shows promise as a potential treatment for cystic fibrosis

ATS 2009, SAN DIEGOCystic fibrosis patients may benefit from a new therapy that increases airway hydration, preventing the buildup of mucous, which is a key factor in the disease, according to researchers at Parion Sciences in Durham, N.C. The research will be presented on Sunday, May 17, during...

TeleHealth Services and UNC-TV Partner to Bring Kids Channel to North Carolina Children's Hospitals

TeleHealth Services, the nation's leading provider of healthcare on-demand patient and staff education, healthcare televisions and communications solutions, has announced a joint initiative with UNC-TV, North Carolina's member-supported statewide television network, to bring UNC-KD, a new digita...

Stanford researcher's discovery of ion channel turns ear on its head

STANFORD, Calif. Scientists thought they had a good model to explain how the inner ear translates vibrations in the air into sounds heard by the brain. Now, based on new research from the Stanford University School of Medicine, it looks like parts of the model are wrong. Anthony Ricci, PhD, as...

SHAPE Raises Heart Attack Awareness on CBS Channel 11

Great Day Houston with Debra Duncan featured former Olympic skating champion, Peggy Fleming, and Dr. Morteza Naghavi of SHAPE as they advocate for heart health awareness and heart attack prevention. Houston, Texas (PRWEB) March 28, 2009 -- Every year over 650,000 people...

ChanTest to Highlight Expanded Ion Channel and GPCR Services and Cell Lines, Including FDA Critical Path Safety Profiling Tools at ToxExpo, Booth 3056

- Company to host seminar Tuesday, March 17, 2009, from 8:30 to 9:30 AM in Room 337 CLEVELAND, Ohio, March 10 /PRNewswire/ -- ChanTest, the leading expert in ion channels and GPCRs (G-protein coupled receptors) - key to drug discovery, development, and safety - will feature the latest in its...

Stratus Technologies Signs Allen Technologies as Newest Channel Partner for High Availability Avance Software

Will ensure at least 99.99 percent uptime for Interactive Patient Care system MAYNARD, Mass., Feb. 17 /PRNewswire/ -- Stratus Technologies, Inc. announced that Allen Technologies, Inc., the leading provider of interactive patient communication systems, has adopted the high availability capabi...

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Channel in Medical Technology

Study Shows Leconotide, an Investigative Calcium Channel Blocker, Has Potential as a Selective, Efficacious, Non-Opioid Pain Treatment

HONOLULU, Jan. 28 /PRNewswire/ -- Results of a pre-clinical study of leconotide, an investigative calcium channel blocker, shows it has the potential to be safe, selective, and efficacious as a new non-opioid treatment for pain relief. It also holds promise in multiple drug delivery options i...

PTC Announces Data Showing That PTC124 Causes Statistically Significant Improvements in Chloride Channel Function in Cystic Fibrosis Patients

- PTC124 Highlighted in Multiple Presentations at North American Cystic Fibrosis Conference - SOUTH PLAINFIELD, N.J. and ORLANDO, Fla., Oct. 24 /PRNewswire/ -- PTC Therapeutics, Inc. (PTC) today announced that results from a randomized Phase 2a European study demonstrated that treatment with...

Ranolazine Shortens QT Interval and Improves Cardiac Relaxation in Study of Patients With Genetic Sodium Channel Disorder

- Clinical evidence for unique Ranexa(R) mechanism of action - CHICAGO, March 31 /PRNewswire-FirstCall/ -- CV Therapeutics, Inc. (Nasdaq: CVTX ) announced today that ranolazine significantly (p<0.001) shortened the QT interval of patients with a hereditary form of long QT syndrome called...

Calcium Channel Blocker Adalat GITS Offer Additional Benefits

ACTION-trial shows medical and economic advantages of nifedipine GITS therapy LEVERKUSEN, Germany, March 28, 2007 – Two recently published articles in the Journal of Clinical Epidemiology provide further evidence that the use of the long-acting calcium channel blocker (CCB) nifedipine...

FDA Issues Complete Response Letter for INTUNIV(TM) (guanfacine) Extended Release for the Treatment of ADHD in Children and Adolescents

...l Sci. 1997;18:211-219. 6. Wang M, Arnsten AF, Brennan A, et al. ÿ±2A-adrenoceptors strengthen working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex. Cell. 2007;129:397-410. 7. Arnsten AF, Li BM. Neurobiology of executive functions: catecholamine influences on ...

Cognition Therapeutics Closes Series A Financing to Advance Drug Candidates for Alzheimer's Disease

... Cognition Therapeutics was founded on small molecule chemical libraries licensed from co-founder Dr. Gilbert Rishton at California State University channel Islands and proprietary screening strategies established by co-founder and Chief Science Officer Dr. Susan Catalano. After initial investment and rel...

Channel in Medical Products

Voltage-Gated Calcium Channel (VGCC) Antibody

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

EK-10 Single Channel ECG

Description: The Burdick EK-10 single-channel electrocardiograph features a simple one-button, soft touch membrane keypad. It provides the necessary information to make a quick and accurate diagnosis. The EK-10 is ergonomically designed with a built in handle for portability perfect visiting practi...
Company:Burdick, Inc.

Elite II Single Channel ECG

Description: The Elite II features a diagnostic interpretation option using the proven University of Glasgow (UG) algorithm. Unlike competitive products, which limit algorithm criteria to age, the UG algorithm bases its analysis on five clinically significant criteria: gender, age, race, medication ...
Company:Burdick, Inc.

Picofluor™ Handheld Dual Channel Fluorometer

Description: Picofluor™ Fluorometer is a lightweight, inexpensive, handheld fluorometer, configured for the fluorescent probes commonly used for nucleic acid and protein quantitation....
Company:Turner Biosystems

EGG 4 Channel Extension

Description: We offer small and large pre-gelled Surface Electrodes suitable for EGG or EMG recordings. Surface Electrodes, Skin Preparation and Conductive Cream complete the setup for a EGG study and are essential for a good EGG tracing....
Company:Medtronic Gastroenterology

Corning Lambda Single Channel Pipettor, 0.1-2.5 ul

Description: This CLS number is a new product number, created to easily match Cornings product number. If showing no availability yet, please order under the old Sigma-Aldrich number (Z71,407-0) or contact customer service for assistance. Mfr Desig: Corning 4959...
Company:Sigma-Aldrich

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Channel in Medical Dictionary

Vein

...o ... The Vein Centre has built a reputation for providing the highest standard of ... Vein Procedures ... Vein Pain. Road of Life. View our channel 4 Better Health ... Despite that, vein disease is often overlooked or under-diagnosed," says Marc ... UAB Vein Clinic. ... Treatments for V...

Urethra

... conveys urine from the floor of the ... These two sphincters control the flow of urine through the urethra . ... placed in the urethra —the channel leading to ... This is because sterile water is used to fill the urethra ... After the inside of the urethra and bladder is ... The uroge...

Phenytoin overdose

...ge, weight, and conditionName of product as well as the ingredients and strength if knownThe time it was ... In overdose , the extent of sodium channel blockade increases, and phenytoin is ... Phenytoin toxicity : Predictions of clinical course. Vet Hum Toxicol 1989; 31: ... Signs and symptom...

Patent foramen ovale

... 3.1.2 Patent foramen ovale . 3.2 Ostium primum atrial septal defect ... A patent foramen ovale (PFO) is a small channel that has little hemodynamic ... Patent foramen ovale — Comprehensive overview covers causes, complications of this heart condition. ... pe...

Papilla

...e location where the Medullary pyramids empty urine into the renal pelvis. Histologically it is marked by medullary collecting ducts converging to channel the fluid. Transitional epithelium begins to be seen. Papilla - Definition of Papilla at Dictionary.com a free online dictionary with ... p...

Hurricane

...f the Atlantic, Eastern Pacific, Western Pacific, South ... The Weather channel provides current hurricane and tropical storm updates with maps, videos, and informational graphics. The Weather channel and weather.com provide a national and local weather forecast for cities, a...

Channel in Biological News

Opening a channel for salt retention

A research team has developed the first small molecule that can reversibly activate a key protein involved in balancing sodium levels, paving the way for drugs that can treat low blood pressure and related conditions. The human epithelial sodium channel (ENaC) controls sodium flow across many ...

Cells direct membrane traffic by channel width

For a glycerol molecule, a measly angstrom's difference in diameter is a road-closed sign: You can't squeeze through unless you are a sleek, water-molecule-sized sports car, say scientists at the University of Illinois at Urbana-Champaign. The roadway is in aquaporins, a class of proteins that fo...

Rodent size linked to human population and climate change

...century, are quite substantial. He had done earlier studies on a century's worth of anatomic changes between two geographically isolated rodents -- channel Island deer mice from coastal California and white-footed mice northwest of Chicago -- and noted fast change among both. "I suspected they weren't ...

'Microfluidic palette' may paint clearer picture of biological processes

...pe, but it could be moreallow various mixtures to flow into the chamber. Beneath the chamber, each access port connects to the long tail of a Y-shaped channel etched into a second layer. These channels deliver test chemicals to the chamber. Fluid flow in and out of the short arms of each Y at constant pressu...

University has grand designs to build a house of straw

...nology and Willmott Dixon. Some of the building has already appeared in the media spotlight. Last year the team helped Kevin McCloud, presenter of channel 4's Grand Designs programme, to build an eco-friendly house in six days using ModCell panels for the Grand Designs Live exhibition. All the wall ...

US-Mexico border wall could threaten wildlife species

...ctivity both people crossing and the border patrols seeking them has to have an effect on wildlife. "Gaps in the fence could help, but that might channel more people to use those open areas for crossing, negating the benefit for wildlife and the purpose for constructing the wall in the first place," he ...

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Channel in Biological Technology

Health Robotics Expands and Diversifies Global Channel Strategies With Joint-Ventures & Direct Operations

BOZEN, Italy, July 13 /PRNewswire/ -- Health Robotics today announced that it has decided to complement its successful indirect channel strategies with direct investments in local infrastructure at a few territories where a couple of Health Robotics' distributors have been negatively affected ...

Cellectricon and BioFocus DPI Advance High Throughput ion Channel Drug Discovery

GOTHENBURG, Sweden, April 27 /PRNewswire/ -- Cellectricon, a leading provider of automated screening solutions for drug discovery, today announced its collaboration with BioFocus DPI, a contract research organization with leading expertise in ion channel screening. BioFocus DPI will utilize Ce...

Cellectricon Partners With The Automation Partnership - Bringing Next Generation Ion Channel Screening System to Market.

GOTHENBURG, Sweden, December 3 /PRNewswire/ -- Cellectricon, a leading provider of screening solutions for drug discovery, today announced the signing of a collaborative agreement with The Automation Partnership (TAP) in the UK, manufacturers of advanced automated systems for cell culture, sample ...

Discovery Channel to Feature Lake Erie Biofuels, LLC

"Shades of Green," a new television documentary on The Discovery Channel, will showcase the cutting edge technology and on-site laboratories at Lake Erie Biofuels, LLC. Erie, PA (Vocus) November 20, 2008 -- Lake Erie Biofuels, LLC , Pennsylvania's first large...

Cepheid Accelerates Direct Sales Channel in UK With Pending Acquisition of Medical Distributor Stretton Scientific

SUNNYVALE, Calif., Nov. 3 /PRNewswire-FirstCall/ -- Cepheid (Nasdaq: CPHD) today announced that it has entered into a definitive agreement to acquire Stretton Scientific Limited, a privately held distributor of scientific diagnostic, measuring and monitoring equipment based in Stretton, Englan...

ChanTest to Highlight the World's Largest Catalog of Ion Channel-Expressing Cell Lines and Discovery Services at Ion Channel Targets, Booth 5

Company CEO is featured speaker: 'Ion Channel Panels for Safety Assessment and Drug Discovery' on Tuesday, September 9th at 2:30 CLEVELAND, Sept. 8 /PRNewswire/ -- ChanTest, the preeminent provider of validated ion channel-expressing cell lines and services for drug-discovery and develo...

Channel in Biological Products

8 Channel Syringe Dispenser, 20 cc Capacity from Biosearch Technologies

Description: Request Info...
Company:Biosearch Technologies

Rabbit Anti-Rat Potassium Channel EAG-1 Antibody, Unconjugated from CHEMICON

Description: Anti-Potassium Channel EAG-1 Immunogen: Synthetic peptide from the C-terminus of rat Kv10.1 (Accession Q63472). The immunogen sequence is identical in mouse and 14/16 residues identical in human. Available Date: 38384...
Company:CHEMICON

Mouse Anti-CNG Channel Monoclonal Antibody, Unconjugated, Clone CNC 9C1 from ABR-Affinity BioReagents

Description: Immunogen: MBP-fusion protein of the C-terminal region of the a2 subunit (amino acids K581-D670) Storage: -20 C, Avoid Freeze/Thaw Cycles...
Company:ABR-Affinity BioReagents

Dacron mesh button tether single channel infusion of rats, sterile from Instech Solomon

Description: These disposable button tethers are designed for rat infusion studies lasting more than 2 weeks. After one to two weeks the subcutaneous tissue will grow into the Dacron mesh, making the sutures irrelevant....
Company:Instech Solomon

Mouse Anti-Mouse BKBeta2 potassium channel Monoclonal Antibody, Unconjugated, Clone N53/32 from UC Davis/NINDS/NIMH NeuroMab Facility

Description: BKBeta2 potassium channel Antigen: Fusion protein amino acids 1-41 (N-terminus) and 218-235 (C-terminus) of mouse BKBeta2 Accession Number: Q9CZM9...
Company:UC Davis/NINDS/NIMH NeuroMab Facility

Mouse Anti-Calcium Channel alpha 2 delta-2 Monoclonal Antibody, Unconjugated, Clone 42 from BD Biosciences Pharmingen

Description: Calcium Channel alpha 2 delta-2 Purified Anti-Mouse, Anti-Rat, Anti-Human clone 42, Isotype Mouse IgG 1 , 150 µg Consult technical datasheet for details....
Company:BD Biosciences Pharmingen

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Channel in Biological Definition

Ion channel

Ion channels are present in the membranes that surround all biological cells . By conducting and controlling the flow of ions , these pore -forming proteins help establish the small negative voltage that all cells possess at rest (see cell potential ). Contents showTocToggle...

Active transport

...ane. An example is the glucose symporter, which cotransports two sodiums for every molecule of glucose it imports into the cell. See also Ion channel ...

Bacterial conjugation

... seem to be the structures through which the actual exchange of DNA takes place; rather, some proteins coded in the tra or trb loci seem to open a channel between the bacteria. The transfer of DNA always runs from the F-positive towards the F-negative bacterium. If the F-plasmid is free, a nick is...

Biophysics

...ain slicing) as well as theoretically (computer models), membrane permitivity, gene therapy, understanding tumors. Pharmacology and physiology - channel biology, biomolecular interactions, cellular membranes, polyketides. Physics - biomolecular free energy, biomolecular structures and dynamics, pro...

Electrophysiology

...o measure the current flowing through a single ion channel and study its behavior. There are different modali... Advantages: Single channels can be recorded and channel properties are not changed. Disadvantages: Poo...tions can be changed. Disadvantages: Risk that channel properties are changed. Perforated patch. ...

Cell membrane

...obic (non polar) and small polar molecules, or facilitated diffusion of polar and ionic molecules, which relies on a transport protein to provide a channel or bind to specific molecules. This spontaneous process decreases free energy, and increases entropy in a system. Unlike active transport, this proces...

Channel in Biological Dictionary

Ion channel

Ion channels are pore-forming proteins that help establish and control the small voltage gradient across the plasma membrane of all living cells by allowing the flow of ions down their electrochemical gradient. They are... Ligand-gated ion channels (LGICs), also referred to as ionotrop...

Sequence homology

..... EBI Tools: Homology and Similarity: blast, fasta, MPsrch, scanps ... Nucleotide sequence similarity searching against the Ligand Gated Ion channel ... sitive and fast sequence homology search algorithms outside of the relational ... present new challenges for sequence homology searchin...

Sarcoplasmic reticulum

...of sarcoplasmic reticulum Ca2+ depletion during spontaneous Ca2 ... posted to sr sarcoplasmic ryanodine reticulum release receptor protein channel ... Zoology information, history, articles and research from Academic Journals, Newspapers, and magazines at HighBeam.com. Free Trial, Credit Card ...

Pericardium

...dium can removed using a needle. ... Pericardium . • Small Intestine. • Spleen. • Stomach. • Triple Burner ... Meeting Point on the Pericardium channel with the Gall Bladder, Liver and Triple ... Information about pericardium in the free online English ... pericardium - a serous membrane with t...

Passive transport

...and English movies, comic strips, activity pages and ... Passive Transport ... Passive ... Diffusion is a means of passive transport . ... channel diffusion is another type of passive transport . ... BACK to main. to passive versus active transport page ... Passive Transport (Fa...

Nick

...elodeon is an American cable television network owned by Viacom International, founded in 1977 as Pinwheel. The Pinwheel name was used until 1981. The channel is found in many different countries, including Nick UK and... Nick at Nite is the evening programming block broadcast over Nickelodeon Sunday ...