What is the suppressing effect of the PPAR-gamma ligands on stomach cancer cells?
...ression one by one via a PPAR- gamma -independent pathway. Moreover, an inductive chemical compound associated with CDDO causes PPAR- gamma -dependent caveolin expression and a PPAR- gamma -independent induction of the apoptosis reaction. This report shows that ciglitazone and troglitazone suppress the pr...Jefferson scientists identify gene mutation potentially involved in breast cancer initiation
... may carry Caveolin-1 mutations, Dr. Lisanti says. caveolin proteins, which play important roles in cell commu... those that were estrogen-receptor negative showed caveolin mutations. "One-third of estrogen receptor-positive patients actually had caveolin mutations, making it one of the most common mutati...Caveolin - Wikipedia, the free encyclopedia
Caveolins are a family of proteins that are involved in receptor-independent endocytosis. The caveolin gene family has three members in vertebrates: CAV1, CAV2, and CAV3, coding for the proteins caveolin-1, caveolin-2 and caveolin-3, respectively. All three members are...Caveolin 3 - Wikipedia, the free encyclopedia
Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities" ... Caveolin-3 directly interacts with the C-terminal tail of beta ...Pfam: Family: Caveolin (PF01146)
Pfam is a large collection of protein families, represented by multiple sequence alignments and hidden Markov models (HMMs) ... Caveolin ...