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Causal in Medical News

Research Finds Causal Link Between Ending Drinking, Depression

But giving mice on the wagon an antidepressant restored brain's ability to make new cells FRIDAY, July 18 (HealthDay News) -- Giving up your few drinks a day may lead to health issues, including depression, a new study says. "Our research in an animal model establishes a causal link...

CSHL scientists trace causal link between a tumor suppressor gene and liver cancer

Scientists at Cold Spring Harbor Laboratory (CSHL) have taken the search for cancer-causing genes an important step forward. In a newly published paper, they confirm that a gene called DLC1 is a tumor suppressor. They have demonstrated in living mice that its deletion, inactivation or loss precipi...

Sex Hormone Protein May Predict Type 2 Diabetes

... used genetic data to confirm that SHBG may play a causal role in the development of type 2 diabetes. "O...y less well-studied," Liu said. While the exact causal mechanism involved in SHBG levels and type 2 diabe...ng in medicine have never focused on the potential causal role of SHBG in the development of disease, Liu no...

Parental Stress Boosts Kids' Asthma Risk

... and we still don't really have a handle on what causes it so we can't control it very well. But this finding contributes to our understanding of that causal process." The report is published in this week's online edition of the Proceedings of the National Academy of Sciences . For the study, Shankar...

96-Week Safety and Efficacy Findings Presented for INTELENCE(TM) (etravirine) As Part of HIV Combination Therapy

... Fat Redistribution: Redistribution and/or accumulation of body fat have been observed in patients receiving antiretroviral (ARV) therapy. The causal relationship, mechanism, and long-term consequences of these events have not been established. Immune reconstitution syndrome has been reported...

New HIV Study Shows That Large Numbers of Women and People of Color Can Be Successfully Enrolled In U.S. HIV Clinical Studies

..., including some fatalities, have been reported. A causal relationship with PREZISTA/r therapy has not been ...lin or oral hypoglycemic agents may be required. A causal relationship between protease inhibitors and these...en observed in patients receiving ARV therapy. The causal relationship, mechanism, and long-term consequence...

Deaths, Injuries Increase With Higher Speed Limits

...hes," he added. Although many factors contribute to passenger injury during a vehicle crash, the kinetic energy transferred to the occupants is the causal agent of injury, Friedman said. "Speed kills. When travel speeds increase, the energy transferred to the occupants of a vehicle during a crash inc...

American Academy of Dermatology Issues Updated Position Statement on Vitamin D

...suggest an association between low levels of vitamin D and an increased risk of certain types of cancers and diseases, the Academy emphasizes that the causal relationship of vitamin D to these disease outcomes has yet to be demonstrated with clinical trials. "It is well documented in the medical l...

Fat-Cell Protein May Reduce Diabetes Risk

...hat he and his colleagues believe that adiponectin isn't just a marker for a decreased risk of type 2 diabetes, but that the protein actually exerts a causal effect on the development of the disease. He said that in animal studies, when adiponectin is injected, metabolic differences occur. And, according to...

Cell transplantation and cardiac repair

... higher cell retention correlated with better changes in observed ejection fraction from baseline to a six-month follow-up. "Our data point toward a causal relationship between the total number of cells that participate in infarct repair and the final enhancement of cardiac function," concluded Dr. Dohman...
Causal in Medical Technology

New Data from the US and Japan Support: No Established Causal Link Between Neuropsychiatric Symptoms and Treatment with Tamiflu US Databases Indicate Psychiatric Symptoms Lower in Influenza Patients Taking Tamiflu Versus Those Not Taking Tamiflu

BASEL, Switzerland, March 20, 2007 -- Clinical studies have shown (1) similar rates of neurologic and psychiatric events in pediatric influenza patients being treated with Tamiflu compared to those receiving no treatment for their influenza. Furthermore, recent data derived from US health insuranc...

Sanofi-aventis Stands Behind the Safety of Lantus(R)

...spective follow-up of four patient registries. The results of these data clearly show that no definitive conclusions can be drawn regarding a possible causal relationship between Lantus(R) (insulin glargine [rDNA] injection) use and the occurrence of malignancies, as the authors of the study point out. ...

Video: Partnership Unites UCB with Consumer Product Innovator OXO(R)

...ripheral neuropathy have been reported in patients treated with CIMZIA; the causal relationship to CIMZIA remains unclear. Exercise caution in considering the...ytopenia, thrombocytopenia) has been infrequently reported with CIMZIA. The causal relationship of these events to CIMZIA remains unclear. Advise all patients...

CVS Caremark Data Confirms Improved Outcomes for Women with Osteoporosis Who are Adherent to Therapy

...e results demonstrate a relationship between osteoporosis, osteoporotic pharmacotherapy, and fractures; however, as in most observational studies, the causal nature of this relationship cannot be strictly determined. "The National Osteoporosis Foundation emphasizes the importance of patient adherence a...

No Causality Found Between Black Cohosh and Liver Problems

... considered by the European Medicines Agency (EMEA) as having a 'possible' or 'probable' causality, concluded that there was in fact no evidence for a causal relationship between treatment with black cohosh and the observed liver problems," explained Dr. Naser, Head of Drug Safety at Schaper & Brummer G...

Ground-Breaking Combination of All-Oral Agents Demonstrates Potential as Hepatitis C Treatment Regimen

...isk factors for stroke, including patients less than 45 years of age. Because these are spontaneous reports, estimates of frequency cannot be made and causal relationship between interferon alfa-based therapies and these events is difficult to establish. The most common adverse events reported for PEG...

Roche and Pharmasset Initiate Phase IIb Clinical Trial of R7128, Most Advanced Nucleoside Polymerase Inhibitor in Development for Chronic Hepatitis C

...isk factors for stroke, including patients less than 45 years of age. Because these are spontaneous reports, estimates of frequency cannot be made and causal relationship between interferon alfa-based therapies and these events is difficult to establish. The most common adverse events reported for PEG...

Video: Zometa(R) Reduces Risk of Breast Cancer Recurrence in Premenopausal Women, Study in The New England Journal of Medicine Reports

...ible. No data are available as to whether discontinuation of bisphosphonate therapy reduces the risk of ONJ in patients requiring dental procedures. A causal relationship between bisphosphonate use and ONJ has not been established. Clinical judgment of the treating physician should guide the management plan...

CVS Caremark Study Finds Non-Adherent Heart Failure Patients Almost Twice as Likely to be Re-Hospitalized Within a Year

...s analysis demonstrate a significant link between medication adherence and health services utilization. However, as in most observational studies, the causal nature of this relationship cannot be strictly determined. About CVS Caremark CVS Caremark is the largest provider of prescriptions in the...

More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies

...ible. No data are available as to whether discontinuation of bisphosphonate therapy reduces the risk of ONJ in patients requiring dental procedures. A causal relationship between bisphosphonate use and ONJ has not been established. Clinical judgment of the treating physician should guide the management plan...
Causal in Medical Definition

Neuropsychiatry

... support for a merge between these specialties. causal pluralism Another broad reason for the divide i... that it is better conceptualised as two ends of a causal continuum (e.g. Kendler, 2005). The benefits of th...gh an understanding of the different levels in the causal process where one can intervene. Indeed, it may be...

Positive predictive value

... virus. In this situation the gold standard used in the evaluation study represents only the presence of a bacteria (that might be harmless) but not a causal bacterial sore throat illness. It can be proven that this problem will affect positive predictive value far more than negative predictive value. To ev...
Causal in Medical Dictionary

Toxocariasis

...pilepsy and seizure diagnosis, treatment, and information for Professionals ... Toxocariasis is caused by nematodes of the genus Toxocara. ... causal Agent, Life Cycle, and Geographic Distribution ... Toxocariasis is caused by larvae of Toxocara canis (dog roundworm) and less ... National Orga...

Schistosomiasis

...is is acquired by swimming, wading, or bathing in fresh water that ... causal Agent, Life Cycle, and Geographic Distribution ... causal Agents: Schistosomiasis is caused by digenetic blood trematodes. ... ...

Oligospermia

... diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis. Hidden causes of Oligospermia including causal conditions & diseases, associated medical conditions, and misdiagnosis of overlooked causes. oligospermia ( ¦äləgō′spərmēə ) ( medicine ) Sc...

Lice Infestation

...nd symptoms of body lice infestation ? The most common signs of body lice infestation are intense itching and a red rash located on ... causal Agent, Life Cycle, and Geographic Distribution ... Eggs: Nits are head lice eggs. ... Head lice infestation is very common and is distributed wo...

Infective endocarditis

...carditis . In Civetta JM, Taylor RW, Kirby RR. ... Infective endocarditis , a serious infection of the endocardium of the heart, ... Although causal agents of infective endocarditis could now be detected and ... Infective endocarditis , a serious infection of the endo ... millennium, ...

Hypogonadism

...diagnostic guides, medical books excerpts online about Hypogonadism . Diagnostic checklist, medical ... Hidden causes of Hypogonadism including causal conditions & diseases, associated medical conditions, and misdiagnosis of overlooked causes. ... and treating hypogonadism in. adult male .....

Hookworm

..., diagnosis, prevention, treatment, and human health risks of hookworms in dogs. ... ( Hookworm infestation in man is sometimes known as ' ... causal Agent, Life Cycle, and Geographic Distribution ... Hookworm is the second most common human helminthic infection (after ascariasis) ... Hookw...

Gingivostomatitis

...nosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis. Hidden causes of Gingivostomatitis including causal conditions & diseases, associated medical conditions, and misdiagnosis of overlooked causes. Gingivostomatitis Information from Drugs.com .....

Genetic Disorders

...ironmental factors. Most disorders are quite rare and affect one person in every... The following is a list of genetic disorders and if known, causal type of mutation and the chromosome involved. The list of human genes includes genes not listed here, which also affect predisposition toward ...
Causal in Biological News

Scientific evidence of health problems from past contamination of drinking water at Camp Lejeune is limited and unlikely to be resolved with further study

...ure to chemicals. The epidemiologic studies of TCE and PCE, primarily conducted in workplace settings, contained insufficient evidence to justify causal inference for any health effects. However, the committee found "limited or suggestive evidence of an association" between chronic exposure to TCE, PC...

Babies born to native high-altitude mothers have decreased risk of low birth weight

...0 weeks of pregnancy compared to the non-pregnant state, and the fetuses were larger at this stage. This suggests that the uterine artery is playing a causal role in the lower birth weight, as opposed to being a result of having a smaller baby and needing less oxygen or fewer nutrients, Dr. Julian said. A...

Study finds genetic links to age of first menstrual period and menopause

...he Women's Genome Health Study (WGHS) based at BWH. "At these newly identified loci, fine mapping or sequencing might lead to identification of the causal variants, and thus expand our knowledge of the underlying physiology and biological regulation of these traits," said lead author Chunyan He, who was ...

Single gene defect can cause stroke, other artery diseases

... M.D., Ph.D., professor and director of the Division of Medical Genetics at The University of Texas Medical School at Houston. The discovery of the causal relationship between the mutated gene ACTA2 and artery diseases has opened the door to a new way of thinking about the vascular system, Milewicz said....

Experts lay to rest long-held misconceptions about high fructose corn syrup at ILSI-USDA workshop

...ffects on satiety, overall energy balance, metabolic hormones or biochemical metabolites such as triglycerides and uric acid all suggesting no unique causal role for high fructose corn syrup in obesity. According to Suzanne P. Murphy, Ph.D., R.D., research professor at the Cancer Research Center of Hawa...

Researchers identify specific lung cancer susceptibility gene

...s scientific findings. "The authors undertook a daunting challenge of performing a family-based study of lung cancer in an effort to identify specific causal genes." Genes, which are located in fixed positions on the cell's chromosomes, carry the DNA code that determines inherited characteristics, inclu...

Alzheimer cell death in Zebrafish: Demise of neurons observed live for the first time

...million patients around the world. This trend is even rising, not least due to the longer life expectancy of people in western society. The search for causal therapies is sorely needed, since neuronal cell death in the brains of Alzheimer's patients can still not be defeated. Moreover, the death of neurons ...

Chinese slimming capsules

...s harmless. Dieter Mller assumes that the consumption of food supplements containing sibutramine is much greater than has been recorded. Moreover, the causal connection is not recognized in many cases and the poison information center is not consulted. The authors therefore urge that manufacturers should be...

Australia's most endangered snake might need burning

... co-author on the new paper published online in British Ecological Society's Journal of Applied Ecology . As part of a 17-year study investigating causal factors in the decline of the colourful broad-headed snake, Professor Shine and colleague Dr Jonathan Webb, also from the University of Sydney, with R...

Differences in neighborhood food environment may contribute to disparities in obesity

...ion of initiatives to promote access to supermarkets, farmers markets, and fruit and vegetable stands and to limit fast-food outlets, the study of the causal relationship between the food environment and diet or body size should be a priority for future research," says Andrew Rundle, DrPh, associate profess...
Causal in Biological Technology

Sanofi-aventis Announces Second Quarter 2009 Results

...le with diabetes were published online by Diabetologia . These analyses clearly show that no definitive conclusions can be drawn regarding a possible causal relationship between Lantus((R)) and an increase in the risk of cancer, as the authors of the study point out. Clinical studies, which represent the g...

Cimzia(R) (certolizumab pegol) Provides Long-Term Remission and Response Rates in Infliximab-Refractory Crohn's Patients

...ripheral neuropathy have been reported in patients treated with CIMZIA; the causal relationship to CIMZIA remains unclear. Exercise caution in considering the...ytopenia, thrombocytopenia) has been infrequently reported with CIMZIA. The causal relationship of these events to CIMZIA remains unclear. Advise all patients...

Avian Adenovirus Genotyping Diagnostic Service

... similar vein, determination of the relationship (or lack of) between source flock adenoviruses and those isolated in progeny flocks and the resultant causal relationship between any observed pathologies has been extremely problematic. To facilitate a clarification of these possible relationships, x-OvO...

Beyond associations: Colorectal cancer culprit found

...pports a direct role for SMAD7 in cancer progression, and very likely the causal basis for colorectal cancer risk associated with this chromosomal region. ...ed to approach the biological mechanism of cancer. By identifying the true causal variants and understanding the biological basis for cancer risk associated ...

Genstruct to Present Results of Collaboration with Top Pharmaceutical Company at American Association for Cancer Research's Annual Meeting

...te and ovarian cancer cell lines using Genstruct's causal Network(TM) modeling platform on RNA expression an...is an excellent example of the capabilities of our causal Network Modeling platform," said Dr. Macoritto. "By using causal modeling, our team of expert scientists was able t...

EPA Awards Lovelace Respiratory Research Institute $500,000 for Air Quality Research

... in America, cardiovascular disease." Project activities involved in this research will include identifying susceptible individuals, classifying causal components of the complex air pollution mixture, and developing a better understanding of the biological mechanisms involved in air pollution-induced ...

FDA Approves ULORIC(R) (febuxostat) for the Chronic Management of Hyperuricemia in Patients with Gout

...c events was observed in patients treated with ULORIC (0.74 per 100 patient-years) than allopurinol (0.60 per 100 patient-years) in clinical trials. A causal relationship with ULORIC has not been established. Monitor for signs and symptoms of myocardial infarction (MI) and stroke. Transaminase elevations ha...

Parion Sciences Receives NIH Biodefense Grant to Study Novel Methods for Mitigating Radiation-Induced Lung Injury

...committed to eradicating respiratory diseases through research aimed at understanding their causes and biological mechanisms, eliminating exposures to causal agents, and developing more effective treatments. For more information see www.lrri.org . ...

New Data Suggest CIMZIA(R) (Certolizumab Pegol) Active in Treating Moderate to Severe Crohn's Patients With Fistulizing Disease

...neuropathy have been reported in patients treated with CIMZIA (R) ; the causal relationship to CIMZIA (R) remains unclear. Exercise caution in consi... thrombocytopenia) has been infrequently reported with CIMZIA (R) . The causal relationship of these events to CIMZIA (R) remains unclear. Advise al...

Genstruct Added to The Biomarker Consortium's Rapidly Growing Roster of Industry Experts

...l research, guide clinical practice and, ultimately, support the development of safe and effective medicines and treatments. Genstruct's proprietary causal Network(TM) Modeling platform for systems biology enables scientists to break down cognitive barriers that impede critical path research. Genstruct's ...
Causal in Biological Definition

Epigenetics

...C.H. Waddington is sometimes credited with coining the term epigenetics in 1942, when he defined it as “the branch of biology which studies the causal interactions between genes and their products which bring the phenotype into being”. However the term goes back at least to 1896 (see Reference...

Gene regulatory network

...ch input, and each output is represented by a node in a directed graph in which there is an arrow from one node to another if and only if there is a causal link between the two nodes. Each node in the graph can be in one of two states: on or off. For a gene, "on" corresponds to the gene being express...

Natural selection

...n acts. It is important to note that the term "natural selection" is often used in the inaccurate yet fairly harmless metaphorical sense as having causal status. To be precise, natural selection is not truly a "mechanism" in itself, as opposed to something like gravity. Instead, natural selection is ...

Vaccine

...04 , 10 of the 13 authors of the original Wakefield study retracted the paper's interpretation, stating that the data were insufficient to establish a causal link between MMR vaccine and autism [6] . Also in 2004, the United States' Institute of Medicine reported that evidence "favors rejection" of any a...
Causal in Biological Dictionary

Resolution

...rd games. Such is the case particularly in the area of conflict resolution . ... The main difference is that resolution requires identifying the causal factors ... (3) alternative means of dispute resolution have been used in the private sector for many years ... of alternative dispute resolutio...

Quaternary structure

... Quaternary Structure is that level of form in which units of tertiary structure ... Identify the mutation in the structure and develop the causal explanation. ... contribute to tertiary structure . and sometimes to quaternary structure ... quaternary structure . Two classes of protei...

Hypothesis

... A hypothesis consists either of a suggested explanation for an observable phenomenon or of a reasoned proposal predicting a possible causal correlation among multiple phenomena. The term derives from the Greek, hypotithenai meaning "to put under" or "to suppose." The......

Genetic disease

...rch ... Genetic diseases are typically diagnosed and treated by geneticists. ... The following is a list of genetic disorders and if known, causal type of mutation and the chromosome involved. The list of human genes includes genes not listed here, which also affect predisposition toward ce...
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(Date:12/22/2014)... Conn. , Dec. 22, 2014  NXT-ID, Inc. (NASDAQ: ... biometric authentication company focused on the growing mobile commerce market, ... Apollo Robbins for the 2015 International CES debut ... Apollo Robbins will be at the NXT-ID booth January ...
(Date:12/19/2014)... , Dec. 18, 2014 Research and Markets ... "Micro Market Monitor: North America Perimeter Security Systems Market" ... The North American perimeter security market is ... to 2019. Although the U.S. market holds a larger share ...
(Date:12/17/2014)... , Dec. 15, 2014 The Defense Logistics Agency ... detect and prevent counterfeit microcircuits from entering into its ... an in-house microcircuit anti-counterfeit initiative dubbed DNA marking. The ... increasing their reliability throughout the supply chain. The new ...
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