Analysis of alcoholics' brains suggests treatment target
...catenin was increased in alcoholics, so they studied it in more detail. In the current study, they evaluated levels of 17 proteins associated with the catenin signaling pathway. This is a powerful tool for examining the abundance of large numbers of proteins simultaneously, said Gu, an assistant professor...Anticancer Properties of Vitamin D Revealed
... Byers and the research team suspected that beta catenin may interact with vitamin D in some fashion because of another known fact — activation of beta catenin causes most colon cancers. To help them under... receptor which only led to rickets. “We know beta catenin is also involved in regulation of hair growth and ...Anticancer Properties of Vitamin D Could Be Separated From Other Functions
...cancer property contained in a protein known as beta catenin. “We know beta catenin is also involved in regulation of hair growth and we wondered if these part...mutation which caused rickets but not alopecia but which still allowed beta catenin to bind to the vitamin D receptor.” If indeed a drug highlighting the anti-...Mayo researchers identify dangerous 'two-faced' protein crucial to breast cancer spread and growth
...v.17 issue of the Journal of Cell Biology . If this protein known as p120 catenin is that powerful, it may be possible to turn the tables on cancer by desig... "When E-cadherin production is lost during the progression of cancer, p120 catenin induces invasion and metastasis," Dr. Anastasiadis says. In this study, ...Two-faced protein can stop metastasis or promote it, researchers say
...cable to most types of tumors." Their laboratory study looks at how p120 catenin interacts with different cadherin cell adhesion proteins in cancer cells. C...mally helps suppress invasion." But researchers have noted that the p120 catenin protein seems mysteriously two-faced: while it normally strengthens cell-ce...