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Cardiomyopathy in Medical News

The structural basis of familial hypertrophic cardiomyopathy is revealed

Familial Hypertrophic Cardiomyopathy (FHC), the leading cause of sudden death in athletes and young people, is a genetic disorder of the heart that is characterized by an increased thickness in tissue of the left ventricle. FHC is thought to be caused by a mutation in the myosin heavy chain, one ...

Men With Angina Do Worse Than Women

...rpreted cautiously, said Dr. Gregg C. Fonarow, a professor of medicine at the University of California, Los Angeles, and director of the Ahmanson-UCLA cardiomyopathy Center. One reason is that a diagnosis of angina does not pinpoint the cause of the chest pain, he said. "Angina is a lot of challenges," Fonarow s...

Texas Health Dallas Receives Double Honor From American Heart Association

...ontinually working to make health care better for our patients." Dr. Gregg Fonarow, chairman of the program and director of the Ahmanson-UCLA cardiomyopathy Center, said as many as 80,000 lives could be saved annually if just the coronary artery disease module, for which Texas Health Dallas was recognized ...

Centocor Ortho Biotech Statement on the FDA ODAC Opinion Regarding DOXIL(R) for Treatment of Advanced Breast Cancer

... mothers Additional Safety Information Cardiac function should be carefully monitored Congestive heart failure or cardiomyopathy may occur after discontinuation of anthracycline therapy For patients with a history of cardiovascular disease, or if the results of cardia...

Gene Mutation Is Linked to Heart Muscle Disease

... Findings shed light on understanding of dilated cardiomyopathy WEDNESDAY, July 15 (HealthDay News) --...t failure in some children and adults with dilated cardiomyopathy have been identified by researchers. Dilated cardiomyopathy -- the most common cause of heart failure in young...

Twitter Boosts CNN Reporter's Fight to Save Her Brother's Life

...se when her brother's condition became life-threatening. Her brother, Eric De La Cruz, 27, is dying in Nevada. He is suffering from severe dilated cardiomyopathy and needs a heart transplant immediately. His heart, weakened and enlarged, is now incapable of pumping blood efficiently. The decreased organ functio...

Reduce Suffering, Urge Heart Failure Patients and Caregivers

...ture of medical care, said Dr. Gregg Fonarow, director of the Ahmanson-UCLA cardiomyopathy Center and associate chief of the UCLA Division of Cardiology at the Univer...ealth Sciences Center, Denver; Gregg Fonarow, M.D., director, Ahmanson-UCLA cardiomyopathy Center, and associate chief, division of cardiology, University of Californ...

What Causes Mystery Heart Condition?

... Stress cardiomyopathy linked to common drugs, study finds TH... News) -- The unusual heart syndrome called stress cardiomyopathy can be triggered by some commonly used heart medic... pump blood. The report that they can cause stress cardiomyopathy might provide at least a partial solution to the r...

Registry Created for Broken Heart Syndrome

...nlike heart attacks, broken heart syndrome -- officially known as Takotsubo cardiomyopathy -- occurs most often in spring and summer months. Symptoms typically mimic ...id. More information The American Heart Association has more about cardiomyopathy . -- Robert Preidt ...

Danon Disease Can Be Quickly Fatal, Study Finds

...is in the March 25 issue of the Journal of the American Medical Association . More information The American Heart Association has more about cardiomyopathy . -- Robert Preidt SOURCE: JAMA/Archives journals, news release, March 24, 2009 ...
Cardiomyopathy in Medical Technology

Cardiac Disease in Women Remains Untreated for Decades

...K, Jan. 26 /PRNewswire-USNewswire/ -- Hypertrophic cardiomyopathy (HCM) is a genetic heart disease that creates a th...s the number one killer in women, the Hypertrophic cardiomyopathy Association ( www.4HCM.org ) warns women remain un... HCMA. For more information about the Hypertrophic cardiomyopathy Association log on to www.4HCM.org . To schedule ...

Study Finds DOXIL(R) Combination Therapy Delays Disease Progression for Patients With Metastatic Breast Cancer

... * Nursing mothers Additional Safety Information * Cardiac function should be carefully monitored - Congestive heart failure or cardiomyopathy may occur after discontinuation of anthracycline therapy - For patients with a history of cardiovascular disease, or if the ...

American Heart Association Journal Report: Miniaturized Heart Pumps May Be Effective for Children Awaiting Transplant

...iventricular assist devices, known as BiVADs, in seven girls and two boys ranging in age from 12 days to 17 years. All had severe heart failure due to cardiomyopathy or complex congenital heart defects and weighed less than 40 kilograms (88 pounds). One child died from kidney failure before receiving a heart transp...

Two DOXIL(R) Studies to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

...XIL -- Nursing mothers Additional Safety Information -- Cardiac function should be carefully monitored -- Congestive heart failure or cardiomyopathy may occur after discontinuation of anthracycline therapy -- For patients with a history of cardiovascular disease, or if the ...

Alseres Pharmaceuticals Enters Agreement to Amend Cethrin(R) License to Lower Milestone Payments and Royalty Rates

...orldwide collaboration and partnership opportunities not only in spinal cord injury but also possibly in other indications like bone repair, oncology, cardiomyopathy and eye disease." Interim six-month results of 37 subjects in a Phase I/IIa clinical trial indicated that Cethrin was safe and well tolerated. The o...

Twelve DOXIL(R) Clinical Studies to be Presented at American Society of Hematology Annual Meeting

...nts of DOXIL -- Nursing mothers Additional Safety Information -- Cardiac function should be carefully monitored -- Congestive heart failure or cardiomyopathy may occur after discontinuation of anthracycline therapy -- For patients with a history of cardiovascular disease, or if the results...

Innovive Pharmaceuticals Announces Preclinical Data from INNO-206 Oncology Program

...w-dose and high-dose groups respectively had low cardiomyopathy scores of one and three on average, in contrast to the doxorubicin group having a high cardiomyopathy score of seven These data suggest that the proposed Phase II dose of 200 mg/m2 should demonstrate mild to no cardiotoxicity in patients. Innovive in...

Pharmion's Amrubicin Shows Encouraging Results Compared to Standard of Care in Second Line Treatment of Small Cell Lung Cancer

...en the two arms. Cardiac adverse events were limited to tachycardia (< grade 3) for one Amrubicin and two topotecan patients. No anthracycline-induced cardiomyopathy has been observed to date. "These results are extremely encouraging and entirely consistent with the data reported from Japanese studies," said Mark...
Cardiomyopathy in Medical Definition

Pathology

...ve stenosis Myocardium Myocarditis - cardiomyopathy ( Dilated cardiomyopathy , Hypertrophic cardiomyopathy , Restrictive...
Cardiomyopathy in Medical Dictionary

Cardiomyopathy

Cardiomyopathy , which literally means "heart muscle disease," is the deterioration of the function of the myocardium for any reason. People with cardiomyopathy are often at risk of arrhythmia or sudden cardiac death or both. Cardiomyopathy — Comprehensive overview covers...

Ischemic cardiomyopathy

Cardiomyopathy , which literally means "heart muscle disease," is the deterioration of the function of the myocardium for any reason. People with cardiomyopathy are often at risk of arrhythmia or sudden cardiac death or both. Ischemic cardiomyopathy is a term that docto...

Dilated cardiomyopathy

Dilated cardiomyopathy or DCM, also known as congestive cardiomyopathy , is a condition in which the heart becomes weakened and enlarged, and cannot pump blood efficiently. The decreased heart function can affect the lungs, liver, and other body systems. Dilated cardiomyopathy — ...

Alcoholic cardiomyopathy

Alcoholic cardiomyopathy is a disease in which the chronic long-term abuse of alcohol leads to heart failure. Alcoholic cardiomyopathy is a type of dilated cardiomyopathy . Due to the direct toxic effects of alcohol on heart muscle, the heart is unable to pump blood... A...

Viral

...d at ... There may be multiple causes including viral infections. ... cardiomyopathy can be classified as primary or secondary. Primary cardiomyopathy can't be ... Information on sore throat, causes, home remedies, preven...

Thromboembolism

...clot in the legs; Thromboembolism . Causes ... Prevention of venous thromboembolism in the geriatric patient.Cardiol Clin. ... Hypertrophic cardiomyopathy is the most common feline heart disease seen in clinical practice. ... number of cats with HCM develop aortic thromboembolism . ... Original...

Infectious endocarditis

...tions 1-10 of 50 total ... Infectious endocarditis . Lipids. Myocardial cardiomyopathy disease. Obesity. Pericardial disease ... Infectious endocarditis...ions 21-30 of 49 total ... Infectious endocarditis . Lipids. Myocardial cardiomyopathy disease. Obesity. Pericardial disease ... Infectious endocarditis...

Heart transplant

...Transplant (Mayo Foundation for ... Heart Transplant (Children's Hospital Boston) ... Heart Transplant Program. Cardiac Psychiatry Program. cardiomyopathy ... A heart transplant is an operation performed to replace a diseased heart with a ... HEART TRANSPLANTATION OVERVIEW Cardiac transpla...
Cardiomyopathy in Biological News

Why 'lazy Susan' has a weak heart

...ch of cardiac insufficiency. For many years, the researchers in Heidelberg have been studying the zebrafish. The genetic variant that suffers from cardiomyopathy is called "Lazy Susan" and got its nickname because of its slow blood flow. Dr. Benjamin Meder and Christina Laufer from Dr. Wolfgang Rottbauer's rese...

New potential therapeutic target discovered for genetic disorder -- Barth syndrome

...ts exhibit defects in cardiolipin metabolism which help fight infections. The various symptoms of BTHS, in addition to cardiolipin deficiency, include cardiomyopathy (weakness in heart muscle), neutropenia (a reduction in neutrophils or white blood cells that fight bacterial infections), muscle weakness & fatigue (...

Studies point to novel target for treating arrhythmias

...ations in troponin genes had been linked to inherited forms of hypertrophic cardiomyopathy (HCM), which carries a high risk of sudden cardiac death. HCM is perhaps mo...tible to arrhythmias and a new therapeutic target for familial hypertrophic cardiomyopathy and other arrhythmia syndromes." The first author of the current report, F...

Research uncovers new steps on pathway to enlarged heart

...xplore the role of the AKAP-Lbc/PKD/HDAC5 signaling pathway in whole animal models to establish whether AKAP-Lbc is a valid biomarker for hypertrophic cardiomyopathy and to determine which genes are initiated upon up-regulation of the anchoring protein," offers Dr. Scott. ...

A search for protection against chemotherapy cardiotoxicity

... population of long-term pediatric cancer survivors mean that, more than ever, cardiotoxicity will continue to remain an important issue for oncology. cardiomyopathy induced by chronic chemotherapy may result, at least in part, from acute cardiotoxic effects accompanying each drug exposure. said Professor Mireille ...

Study offers clues to 'Broken Heart Syndrome'

... interventional cardiologist finds no blockage in the coronary arteries. To date, the registry has enrolled 40 patients diagnosed with Takotsubo cardiomyopathy at two major hospitals in Rhode Island over a period of nearly 2½ years. Ninety-five percent were women, and 60 percent experienced some type of stres...

Heart failure: Intervention possibilities from imaging programmed cell loss

...art muscle," he added. "This research is significant since cell loss is potentially reversible and earlier intervention could delay the development of cardiomyopathy or heart muscle disease," noted Hofstra. He indicated that additional research is needed since the study was performed on a small group of heart patie...

Are one-third of costly implanted heart devices unnecessary? New study suggests yes

.... Last spring, they published results from the same group of ischemic cardiomyopathy patients, showing that the MTWA test was able to predict the risk of death ...ew study results. This research has focused on patients with ischemic cardiomyopathy ?the most common form of heart-muscle damage that weakens the heart's pumpi...

Protein overexpression at heart of heart failure

... Chronic heart failure resulting from dilated cardiomyopathy is rapidly emerging as a disease of epidemic proportions.1 Molecular mechanisms are being studied and advances have been made in a minority of cases, ...

Study finds 60 new genes controlled by DNA snippet

...cle cells' ability to contract. That in turn reduces the pumping strength of heart muscle and leads to heart failure, according to recent studies. Can cardiomyopathy be reversed by manipulating CArG-SRF? CArG sequences also appear near genes that direct the building of nerve cells and blood vessels, suggesting they...
Cardiomyopathy in Biological Technology

Novel gene found for dilated cardiomyopathy

Researchers in the Heart Institute at Cincinnati Children's Hospital Medical Center have discovered a novel gene responsible for heart muscle disease and chronic heart failure in some children and adults with dilated cardiomyopathy (DCM). Mutations in the ANKRD1 gene may cause DCM, which is the...

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

... Additional Safety Information Cardiac function should be carefully monitored Congestive heart failure or cardiomyopathy may occur after discontinuation of anthracycline therapy For patients with a history of cardiovascular disease, or if the results of card...

RSCI Announces World-Leading Stem Cell Science Advisory Board

...rization. This procedure produces significantly less "spillage," maximizing cell utilization at the target region. In May he saved a young cardiomyopathy patient with serious complications by developing a new multi-faceted comprehensive stem cell treatment procedure. Dr. Grekos treats pulmonary hyperte...

Amgen Exercises Option for Exclusive License to Cytokinetics' Cardiac Contractility Program That Includes CK-1827452

... Phase 2a clinical trial was designed to evaluate an intravenous formulation together with an oral formulation of CK-1827452 in patients with ischemic cardiomyopathy and angina. Cytokinetics also plans to present data from this trial at the 2009 Heart Failure Congress of the European Society of Cardiology. Top-line...

Cordex Pharma Forms Heart Failure Medical Advisory Board

... at Boston University School of Medicine . He is also the Chief of Cardiovascular Medicine, Director of the Myocardial Biology Unit, Director of the cardiomyopathy Program and Co-Director of the Cardiovascular Center at Boston Medical Center. Howard J. Eisen, M.D., F.A.C.C., F.A.C.P., F.A.H.A., is the Thomas...

Repair Stem Cell Institute Announces Science Advisory Board

... Dominican Republic, is a RSC innovator. In April 2008 he saved a young meningitis patient's arms and legs from amputation and in May he saved a young cardiomyopathy patient with serious complications by developing a new multi-faceted comprehensive repair stem cell treatment procedure. He has collaborated with the ...

Hsiao Dee Lieu, M.D., F.A.C.C. Named VP of Clinical Research of Nile Therapeutics

...ascular Disease at the University of California at San Francisco (UCSF) conducting molecular cardiology research in gene manipulation and induction of cardiomyopathy and atherosclerosis regression. Dr. Lieu currently serves as Assistant Clinical Professor of Medicine, Cardiology Division at UCSF. Dr. Lieu complet...
Cardiomyopathy in Biological Dictionary

Left ventricle

...agnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis. Learn about enlarged left ventricle (from cardiomyopathy or valvular heart disease) and treatment options from MedicineNet's expert doctors and healthcare professionals. Hypoplastic Left Heart Syndrom...

Intercalated disc

...necessary energy for contraction. To facilitate energy and calcium conductance in cardiac muscle... Key Words: intercalated discs • kindlin-2 • cardiomyopathy • integrin ... Thus, the intercalated discs ensure proper function of the heart with efficient ... ... Mechanical and Electrical Junctions at...
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