Carcinogen

Tanning Beds Get Highest Carcinogen Rating

Melanoma risk rises 75 percent when device use begins before age 30, international panel says TUESDAY, July 28 (HealthDay News) -- The International Agency for Research on Cancer on Tuesday moved tanning beds to its highest cancer risk category -- "carcinogenic to humans," according to...

Gene 'knockout' floors tobacco carcinogen

In large-scale field trials, scientists from North Carolina State University have shown that silencing a specific gene in burley tobacco plants significantly reduces harmful carcinogens in cured tobacco leaves. The finding could lead to tobacco products especially smokeless products with redu...

Soaking Potatoes Before Frying Cuts Suspected Carcinogen

Findings show even a simple washing reduces acrylamide levels by up to 23% THURSDAY, March 6 (HealthDay News) -- Soaking potatoes in water before frying cuts down on the formation of the suspected carcinogen acrylamide, says a a new, British study. Acrylamide is created when starch-...

Non Smoking Workers Absorb the Carcinogen Immediately

Scientists have found that nonsmoking restaurant and bar employees absorb a potent carcinogennot considered safe at any levelwhile working in places where they had to breathe tobacco smoke from customers and co-workers. The carcinogen, NNK, is found in the body only as a result of using tobacco or...

Agent Orange Linked to Parkinson's, Heart Disease

...y; Agent Orange was the herbicide used most often to accomplish this goal. The International Agency for Research on Cancer reclassified TCDD a group 1 carcinogen in 1997, a classification that also includes arsenic, asbestos and gamma radiation, according to background information in the study. The IOM's rep...

Researchers find possible environmental causes for Alzheimer's, diabetes

...which then alters gene expression and causes DNA damage. The researchers note that the role of nitrosamines has been well-studied, and their role as a carcinogen has been fully documented. The investigators propose that the cellular alterations that occur as a result of nitrosamine exposure are fundamentally si...

Wildlife faces cancer threat

...l cancer, which is their second leading cause of death. One type of pollutant in these waterspolycyclic aromatic hydrocarbons (or PAHs)is a well-known carcinogen in humans, and PAHs are suspected carcinogens for beluga whales as well. Fish in other industrialized waterways, including brown bullhead catfish and ...

New Study Indicates Changes in Cigarette Design Have Increased Lung Cancer Risk and Tobacco Regulation Can Greatly Reduce Lung Cancer

... countries. One major known difference in cigarettes between the two countries is the lower levels of tobacco specific nitrosamines (a lung specific carcinogen for adenocarcinoma) in Australian cigarettes. The increased risk of adenocarcinoma in the U.S. may be explained by the higher levels of tobacco spec...

Agent Orange Exposure Tied to Prostate Cancer Return

...at exposure to Agent Orange, which was used during the Vietnam War, increases the risk for a number of health problems. Agent Orange contained a known carcinogen called dioxin, which is also found in herbicides and pesticides used by U.S. farmers, according to background information in the news release about th...

Charring Meat May Boost Risk of Pancreatic Cancer

...st 60 percent more likely to get pancreatic cancer compared to those who ate steak less well done or did not eat steak. Researchers then estimated carcinogen intake based on overall meat consumption and doneness preferences. Those with highest intake had 70 percent higher risk than those with the lowest int...

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Carcinogen in Medical Technology

Ground-Breaking Combination of All-Oral Agents Demonstrates Potential as Hepatitis C Treatment Regimen

...ociated with ribavirin therapy may result in a worsening of cardiac disease. Ribavirin is genotoxic and mutagenic and should be considered a potential carcinogen (see CONTRAINDICATIONS, WARNINGS, PRECAUTIONS and ADVERSE REACTIONS in complete product information). PEGASYS is contraindicated in patients wit...

Roche and Pharmasset Initiate Phase IIb Clinical Trial of R7128, Most Advanced Nucleoside Polymerase Inhibitor in Development for Chronic Hepatitis C

...ociated with ribavirin therapy may result in a worsening of cardiac disease. Ribavirin is genotoxic and mutagenic and should be considered a potential carcinogen (see CONTRAINDICATIONS, WARNINGS, PRECAUTIONS and ADVERSE REACTIONS in complete product information). PEGASYS is contraindicated in patients wi...

Preventing Prostate Cancer and BPH: Prostate-Health Expert Available (National Men's Health Week Is June 9-15)

...bacco as a source of cadmium, a heavy metal that has been linked to prostate cancer in several occupational-health studies. This known human carcinogen inhibits DNA repair, which allows cancer cells to mutate and multiply. -- African-American men are known to have a higher risk of prostat...

Initial Results of Phase II Study with HCV Protease Inhibitor Boceprevir in Treatment-Naive Hepatitis C Patients Show a High Rate of Early Virologic Response

...ssociated with REBETOL therapy may result in a worsening of cardiac disease. Ribavirin is genotoxic and mutagenic and should be considered a potential carcinogen Contraindications PEGINTRON is contraindicated in patients with hypersensitivity to PEGINTRON or any other component of the product, autoimmune hepa...

European Union's CHMP Issues Positive Opinion on PEGINTRON(TM) Combination Therapy for Retreating Hepatitis C Patients Who Failed Previous Therapy

...ssociated with REBETOL therapy may result in a worsening of cardiac disease. Ribavirin is genotoxic and mutagenic and should be considered a potential carcinogen Contraindications PEGINTRON is contraindicated in patients with hypersensitivity to PEGINTRON or any other component of the product, autoimmune hepa...

Immunosuppressant Drug Prevents Tobacco Induced Lung Cancer in Mice

...istered rapamycin one week after exposure to a very common tobacco-specific carcinogen showed a 90 percent decrease in the number of tumors, a 74 percent decrease... new tumor formation and on established tumors. Mice were exposed to NNK (a carcinogen only found in tobacco) through injection into the peritoneum (the area that...

Carcinogen in Medical Definition

Pathology

...py - Immunotherapy - Experimental cancer treatment Misc. Tumor suppressor genes / oncogenes - Staging / grading - Carcinogenesis - carcinogen - Research - Paraneoplastic phenomenon - ICD-O - List of oncology-related terms v • d • e Pathology : hema...

Ocular oncology

...py - Immunotherapy - Experimental cancer treatment Misc. Tumor suppressor genes / oncogenes - Staging / grading - Carcinogenesis - carcinogen - Research - Paraneoplastic phenomenon - ICD-O - List of oncology-related terms ...

Carcinogen in Medical Dictionary

Carcinogen

The term carcinogen refers to any substance, radionuclide or radiation that is an agent directly involved in the promotion of cancer or in the increase of its propagation. This may be due to the ability to damage the genome or to the disruption of cellular metabolic... Carcinogens are subst...

Diethylstilbestrol

...made) drug that ... Diethylstilbestrol diphosphate helps to treat and relieve the symptoms of ... Diethylstilbestrol is known to be a human carcinogen based on sufficient ... utero (" diethylstilbestrol daughters"), which found that ... Women's health information covers breast, cancer, heart, pr...

Aflatoxin

... other hand, aflatoxin may be present, even though no outward indications ... ... facts about aflatoxins . ... Aflatoxin B1 is a very potent carcinogen in many species, ... well-developed countries, aflatoxin contamination rarely occurs ... AFLATOXIN M1. First ... a marker of intake of aflat...

Carcinogen in Biological News

Improved method developed to test carcinogen risk

CORVALLIS, Ore. Researchers at Oregon State University recently completed the largest animal study ever done in the field of toxicology, and the findings challenge some basic concepts about how to determine what level of a cancer-causing compound can be considered safe. The study found that ac...

McGill researchers shed light on formation of carcinogen in food

Furan, a potentially dangerous chemical has been found by Health Canada and the U.S. Food and Drug Administration (FDA) in processed foods, especially canned or bottled foods. A new study by McGill researchers Dr. Varoujan Yaylayan and graduate student Carolina Perez Locas explains the presence of ...

Glutamine supplements show promise in treating stomach ulcers

...s finding in the clinical setting. " H. pylori bacteria infect more than half of the world's population and were recently identified as a Group 1 carcinogen by the World Health Organization," she adds. "Approximately 5.5 percent of the entire global cancer burden is attributed to H. pylori infection and,...

Gutsy germs succumb to baby broccoli

...Fahey says, which confirms previous findings for a role of Nrf2 in protection against H. pylori -induced inflammation and gastritis. Classified a carcinogen by the World Health Organization, H. pylori is a gastrointestinal tract germ that manages to thrive in the lining of the stomach despite the strengt...

More than skin deep: There's no such thing as a 'safe' suntan, researchers warn

..., including causing DNA damage, photoaging (damage to the skin from chronic exposure to sunlight) and skin cancer. UV radiation is the most ubiquitous carcinogen (cancer-causing agent) for humans, in whom skin is the organ most commonly affected by cancer. Although more research is required, published data s...

New and revised limits ensure safety in the workplace

...nt of many biomolecules in the body is very useful for natural substances such as rubber and for many aromatic compounds in industry, is known to be a carcinogen and is able to modify germ cells. Following a comparison with the so-called endogenous concentration however, i.e. that formed as part of the body's m...

Early treatment of stomach infection may prevent cancer

...lori. Although H. pylori infection is now recognized as the major cause of both peptic ulcers and gastric cancer, and has been classified as a group I carcinogen by the World Health Organization, physicians are not sure whom to screen and treat with costly antibiotics, aside from first degree relatives of gastr...

Impacts of fossil fuels on fish and people

...l of 1989. Certain PAHs were recognized as carcinogenic more than a century ago, but a class of PAHs with a different structure was ruled out as a carcinogen and was largely ignored. What Incardona learned was that this class of PAHs, also found in oil, is toxic to the developing hearts of fish. This sa...

Fighting pollution the poplar way: Trees to clean up Indiana site

...t of the surface, making it accessible to poplar roots, he said. TCE, the most common groundwater pollutant on Superfund sites, is a probable human carcinogen and causes various health problems when present in sufficiently high levels in water or air. Meilan said planting transgenic trees in the field rem...

Scientists develop a fast system to detect metal concentrations in iron and steel industry workers

... Gil Fernndez also discussed the poisonous character of everyday items such as batteries. For example, the cadmium in these batteries is a potential carcinogen which can produce lung and testicle cancers among others hence the importance of an adequate waste treatment system. Furthermore, Gil Fernndez covere...

Carcinogen in Biological Technology

Calling for a Cure

...bestos in children's toys demonstrates the shocking reality that the deadly carcinogen is virtually everywhere in our environment. For decades, asbestos was use...ds; and even in common consumer products like hair dryers. As a result, the carcinogen has permeated our homes, offices and schools. The EPA estimates that one as...

Analysis Of Chloramphenicol by Negative Ion Electrospray LC/MS/MS

... Z. Yang, Varian, Inc. Introduction Chloramphenicol (CAP) is a potent, broad-spectrum antibiotic and potential carcinogen used in humans only at therapeutic doses for treatment of serious infections. Its use in meatproducing animals, food producing insects, aquaculture, a...

Tissue Specificity for Mutation Parallels Tissue Specificity for Cancer

...designed studies to assess mutations in a range of tissues after carcinogen treatment have addressed whether mutations are induced selective...tris(2,3-dibromopropyl)phosphate (TDBP) is an established kidney-specific carcinogen in male and female rats and male mice; in female mice, it targets the liv...

Carcinogen in Biological Products

Cell Transformation Colorimetric Assay Kit from CHEMICON

Description:... which is considered the most stringent assay for detecting malignant transformation of cells. For this assay, cells (pre-treated with carcinogens or carcinogen inhibitors) are cultured with appropriate controls in soft agar medium for 21-28 days. Following this incubation period, formed colonies can either b...
Company:CHEMICON

Carcinogen in Biological Definition

Cancer

...ntion Prevention is defined as the reduction of cancer mortality via reduction in the incidence of cancer. This can be accomplished by avoiding a carcinogen or altering its metabolism ; pursuing lifestyle or dietary practices that modify cancer-causing factors or genetic predispositions ; and/or medical ...

Carcinogen in Biological Dictionary

Intestine

.... anus F. appendix G ... structure of the intestine varies greatly in ... Small Intestine Cancer Key Terms: Adenocarcinoma , Angiosarcoma , carcinogen , Carcinoid , Leiomyosarcoma , Liposarcoma , Lymphoma , Malignant , In anatomy, the intestine is that tubular portion of the Gastrointestinal tra...

Ames test

...Ames test is a biological assay to assess the mutagenic potential of chemical compounds. A positive test indicates that the chemical might act as a carcinogen . As cancer is often linked to DNA damage, the test also serves as a quick assay to estimate the carcinogenic potential of a compound since it i...