Serum carcinoembryonic antigen level can reflect adrenal adenoma
The female patient, reported on the December 7 issue 45 of World J Gastroenterology, presented a rare case, with symptoms consistent with hyperadrenocorticism and hypercatecholaminism, and also had a Cushingoid appearance. The serum cortisol, dopamine and noradrenalin levels were elevated. Compute...
Many colorectal cancer survivors do not receive recommended follow-up care
...sis. The study investigators considered the screening guidelines to be fulfilled if a patient received two or more office visits per year, two or more carcinoembryonic
antigen (CEA) tests per year, and at least one colonoscopy within three years.
Overall, six in ten (60.2 percent) of patients received testing belo...
Targeted Anticancer Drugs - In Vitro Assessment and Non-Invasive Imaging of Patient and Tumor Status Will Determine Clinical and Commercial Success
... ATP synthase [alpha] subunit;
axl; Bap31; Bcl-xL; Bcl-2; bcr-abl/abl (including mutated forms); B-FN
(ED-B fibronectin); carboxyanhydrase IX (CA IX); carcinoembryonic
(CEA); cathepsin K (CTSK); C-C chemokine receptor 4 (CCr4); CD105
(endoglin); CD13; CD19; CD20; CD22; CD25; CD3; CD30; CD33; CD38; CD4; CD40;
Immunotherapy: enlisting the immune system to fight cancer
...archers gave patients an intravenous dose of MFECP1, a recombinant fusion protein consisting of a fragment of an antibody raised against the substance carcinoembryonic
antigen (CEA), which is produced by the cancer, and carboxypeptidase
G2 (CPG2), an enzyme that activates a prodrug. Then, researchers gave patient...
Histochemistry is the golden standard in the diagnosis of carcinosarcomas
...n standard in the diagnosis of carcinosarcomas: epithelial component expressed positivity for cytokeratin 18, epithelial membranous antigen (EMA), and carcinoembryonic
antigen (CEA). Chromogranin A positive epithelial cells could also be observed. The mesenchymal component had intensive staining for vimentin, althou...
Carcinoembryonic in Medical Technology
Carcinoembryonic in Biological News
Plasma DNA level is a reliable marker of recurrent esophageal cancer, study finds
... for better selection of patients for adjuvant therapy, prediction of response to therapy and early intervention when the disease does recur. Although carcinoembryonic
antigen (CEA) and plasma DNA are known to be elevated in patients with esophageal cancer and are higher in patients with metastatic disease, the sensi...
Nanowires can detect molecular signs of cancer, scientists find
...res conducting a small current with antibody receptors for certain cancer markers -- such as prostate specific antigen (PSA), PSA-a1-antichymotrypsin, carcinoembryonic
antigen and mucin-1. When these telltale proteins come into contact with a receptor, it sparks a momentary change in conductance that gives a clear in...
Carcinoembryonic in Biological Technology
Pre-Clinical Data on CEA-specific BiTE Antibody Published in Journal of Immunotherapy Demonstrate Potent Control of Tumor Growth
...d the publication of data in the peer-reviewed Journal of Immunotherapy (1) demonstrating the potent anti-tumor activity of a BiTE antibody binding to carcinoembryonic
antigen (CEA) and to CD3 on T cells. Micromet and MedImmune are jointly developing MT111/MEDI-565, a CEA-specific BiTE, which is in pre-clinical devel...
Micromet to Present Six Posters on Progress of BiTE Antibodies at the Annual Meeting of American Association for Cancer Research
...n 'Immunology 5' on April 21, 2009, 8:00 AM in Hall B-F, poster section 12.
Oberst, M. et al. (2009). In vitro pharmacological comparison of a carcinoembryonic
antigen (CEA; CEACAM5; CD66e)/CD3 bispecific cynomolgus-reactive BiTE antibody (CyS111) biosimilar with the clinical candidate MEDI-565 (MT111). AACR ...
AMDL, Inc. Enters Into Collaboration Agreement to Advance Development of Its AMDL DR-70 (FDP) Cancer Test
...ue to undetected metastases.** Frequent surveillance of diagnosed patients is recommended, but current procedures have shortcomings. This includes the carcinoembryonic
Antigen blood test currently used for surveillance of CRC, which suffers from poor sensitivity and specificity (i.e. the ability to determine if someo...
Purification of Murine IgG1 Using UNOsphere S and CHT
Ceramic Hydroxyapatite Chromatography, Rev A
Ford CH et al., Affinity purification of novel bispecific antibodies recognising
antigen and doxorubicin, J Chromatogr B Biomed Sci and
Appl 754, 427435 (2001)
Godfrey MAJ et al., Assessment of th...