New drug candidate prolongs the lives of pancreatic cancer patients

Every year, 42,000 Americans are diagnosed with pancreatic cancer. Few live very long, and less than 5% are still alive five years after diagnosis. There's new hope, though, from the lab of Prof. Yoel Kloog, dean of Tel Aviv University's Faculty of Life Sciences. His drug compound Salirasib has...

Amira Pharmaceuticals Announces Initial Positive Phase 1 Clinical Data for AM211, a Novel Product Candidate for the Treatment of Respiratory Diseases

Results Demonstrate Positive Proof of Mechanism SAN DIEGO, June 30 /PRNewswire/ -- Amira Pharmaceuticals, Inc. announced today initial positive data from a Phase 1 clinical study of AM211, the company's oral selective antagonist of the DP2 (also known as CRTH2) receptor. The interim resu...

Promising biomarker and candidate tumor suppressor gene identified for colorectal cancer

Researchers have identified a new candidate tumor suppressor gene in colorectal cancer and examined its use as a potential biomarker in stool samples, according to a new study published online June 17 in the Journal of the National Cancer Institute . In the study, Manon van Engeland, Ph.D., of...

MAP Pharmaceuticals Phase 3 Trial of LEVADEX(TM) Migraine Product Candidate Meets All Four Primary Endpoints

- Both Rapid and Sustained Pain Relief for up to 48 Hours - - Conference Call to be Held Today at 8:30 a.m. ET - MOUNTAIN VIEW, Calif., May 26 /PRNewswire-FirstCall/ -- MAP Pharmaceuticals, Inc. (Nasdaq: MAPP ) announced today that the efficacy portion of its first Phase 3 clinical t...

CDC Has Candidate Viruses for Swine Flu Vaccine

If viable, these ingredients could be sent to manufacturers by month's end FRIDAY, May 22 (HealthDay News) -- A viable H1N1 swine flu vaccine got a bit nearer Friday, with government health officials saying they had two promising candidate viruses for use in such a shot. "Today CDC...

Aethlon Medical Confirms Hemopurifier(R) Is a Treatment Candidate Against Swine Flu Virus

SAN DIEGO, April 30 /PRNewswire-FirstCall/ -- Aethlon Medical, Inc. (OTC Bulletin Board: AEMD) confirmed today that the Aethlon Hemopurifier(R) is a candidate to treat the H1N1 Swine flu virus. The Hemopurifier(R) is a first-in-class medical technology that assists the immune response in combatin...

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Candidate in Medical Technology

Lexicon's Drug Candidate LX1032 for Carcinoid Syndrome Receives Orphan Drug Designation From EMEA

THE WOODLANDS, Texas, July 21 /PRNewswire-FirstCall/ -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX ), a biopharmaceutical company focused on discovering and developing breakthrough treatments for human disease, announced today that it has received orphan d...

Cardax Pharmaceuticals Nominates Clinical Candidate Heptax for Liver Disease; Heptax Ameliorates Inflammation and Oxidative Stress Related to Liver Disease and Metabolic Syndrome

AIEA, Hawaii, July 20 /PRNewswire/ -- The Centers for Disease Control and Prevention reported this week that the prevalence of obesity among Americans is now over 26%. Obesity exacerbates a constellation of diseases including diabetes, liver disease, and heart disease, often in...

Vantia Therapeutics' Lead Candidate VA106483 Demonstrates Positive Anti-diuretic Effect in Phase IIa Trial in Nocturia

SOUTHAMPTON, England, June 29 /PRNewswire/ -- Vantia Therapeutics, an emerging pharmaceutical company developing novel, small molecule drugs targeting large, underserved medical markets, announces positive results from a Phase IIa clinical trial of its lead development compound VA106483 for no...

CeNeRx BioPharma Obtains Rights to Novel Drug Candidate for Prevention and Treatment of Neurodegeneration Disorders

--Orally Active Enhancer of Human Nerve Growth Factor Has Demonstrated Promising Activity Preclinically-- --Broad Potential Applications Include Neuropathies, Alzheimer's and Huntington's Disease and Others-- RESEARCH TRIANGLE PARK, N.C., June 16 /PRNewswire/ -- CeNeRx BioPharma, Inc., a...

Lilly Advances Second Alzheimer's Disease Treatment Candidate Into Late-Stage Testing by Launching Two Global Trials

Both Phase III pivotal trials begin enrollment in May 2009; Reinforces Lilly's commitment to Alzheimer's disease and biotech product research INDIANAPOLIS, May 21 /PRNewswire-FirstCall/ -- Eli Lilly and Company (NYSE: LLY ) today announced it will begin enrolling patients this month in two...

Potentia Pharmaceuticals' POT-4 Drug Candidate for Age-Related Macular Degeneration Successfully Completes Phase I Clinical Trial - Prepares for Phase II

POT-4 well tolerated by all subjects and sustained levels of drug reported after one treatment LOUISVILLE, Ky., May 4 /PRNewswire/ -- Potentia Pharmaceuticals, a privately held biotechnology company developing medicines for the treatment of age-related macular degeneration (AMD), announced to...

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Candidate in Medical Products

ABI Testing Kit

Description:...shows the step-by-step procedure of performing an ABI test, provides information on the materials that are needed, and indicates who is an appropriate candidate for the test. Also included in the packet is a quick-reference booklet of the CD presentation, a patient information brochure, and a report form and v...
Company:Nicolet Vascular

Candidate in Medical Definition

Depolarization-induced suppression of inhibition

... observed (Herkenham et al. 1990). The CB1 receptor also appears to be expressed mainly on GABA-ergic pre-synaptic terminals, making it an excellent candidate for mediating DSI (Matyas et al. 2006, Katona et al. 1999). In 2005, other groups began to demonstrate the involvement of the CB1 receptor in DSI ...

Candidate in Medical Dictionary

Spinal fusion

...dure is done from the front and the back ... Minimally invasive lumbar spinal fusion is an operation that is less invasive to ... Am I a candidate for minimally lumbar invasive spinal fusion ? ... Spinal fusion is usually done along with other surgical procedures of the spine. ... ...

Primary

... primary adj. First or highest in rank, quality, or importance; principal. ... primary , in the United States, a preliminary election in which the candidate of ... Brief and Straightforward Guide: What is a Primary Election? ... An open primary election means anyone can vote, despite his or her pol...

Lung transplant

...lung transplant program in the country depends on the generosity of ... To have a lung transplant (Tx), one must be evaluated as a suitable candidate ... I had a double- lung transplant in April '95. I was on the waiting list for ... More about Lung Transplantation : Purpose Precautions Pr...

Lobectomy

...obectomy . Lung Cancer Treatment. Non-Small Cell Lung Cancer ... Discover how a lobectomy is performed in order to treat lung cancer. ... Who is candidate for lobectomy : ... Patients who undergo a lobectomy face the risk of ... Description and illustrations of different operations for thyroid nod...

IUD

...wer than 1 out of 100 women per year will get pregnant using an IUD . ... NYabortion.com - call us 877-i-matter - birth control ... Am I a good candidate for the copper IUD ? Are there any reasons why I shouldn't use the copper IUD ? ... Find out if the intrauterine device ( IUD ) is the right ...

Granulocyte

... Original Article from The New England Journal of Medicine -- Granulocyte -Macrophage Progenitors as candidate Leukemic Stem Cells in Blast-Crisis CML Original Article from The New England Journal of Medicine -- Mutations in the Gene for the Granulocyte C...

Candidate in Biological News

Pitt researchers find promising candidate protein for cancer prevention vaccines

PITTSBURGH, Aug. 4 Researchers at the University of Pittsburgh School of Medicine have learned that some healthy people naturally developed an immune response against a protein that is made in excess levels in many cancers, including breast, lung, and head and neck cancers. The finding suggests t...

Scientists identify a candidate gene for osteoporosis

Today, researchers report the identification of a gene that may play a role in susceptibility to osteoporosis—the crippling disease that leads to bone fractures, especially of the hip and spine. The study, conducted by scientists at the Musculoskeletal Diseases Center of the Jerry L Pettis Memorial...

U of S researchers develop new vaccine candidate against hepatitis C

Researchers at the University of Saskatchewan's Vaccine and Infectious Disease Organization (VIDO) have developed a vaccine candidate for hepatitis C, leading to hope in the fight against a disease for which no vaccines are yet available. VIDO is the first in Canada to show that this vaccination ...

New HIV drug candidate developed in Sweden

Which is more likely to happen - you being in a car wreck or being bitten by a shark? Those who answered that cars are greater killers win a free trip to the beach. It's really no contest, says a Texas A&M University professor. Your chances of being in a wreck are far greater than being a sh...

Study reveals candidate targets for anti-retroviral therapeutics

The increased frequency of drug resistance in isolates of the AIDS virus, HIV, makes identification of new antiviral targets an urgent necessity. Host genes required to support the replication of HIV are a potential source of such novel targets, but relatively few appropriate target genes have been...

The hepatitis healing power of blueberry leaves

... progression. So they screened nearly 300 different agricultural products for potential compounds that suppress HCV replication and uncovered a strong candidate in the leaves of rabbit-eye blueberry (native to the southeastern US). They purified the compound and identified it as proanthocyandin (a polypheno...

Candidate in Biological Technology

Omnio Healer Selects Eden Biodesign for cGMP Production of its Candidate Wound Healing and Anti-Infection Treatments

UMEA, Sweden, August 6 /PRNewswire/ -- Omnio Healer AB, a pioneer company developing novel therapies for wound healing and anti-infection, today announced that it has entered into a partnership agreement with Eden Biodesign. Under the agreement Eden Biodesign will provide process development a...

Medicago's H1N1 pandemic vaccine candidate shows positive response in 100% of vaccinated animals after a single dose

QUEBEC CITY, July 30 /PRNewswire-FirstCall/ - Medicago Inc. (TSX-V: MDG) a biotechnology company focused on developing highly effective and affordable vaccines based on proprietary manufacturing technologies and Virus-Like Particles (VLPs), today announced that it has achieved additional positive ...

Novavax Announces Selection of a Respiratory Syncytial Virus Vaccine Candidate for Advanced Preclinical Studies

ROCKVILLE, Md., July 22 /PRNewswire-FirstCall/ -- Novavax, Inc. (Nasdaq: NVAX ) announced today final selection of a Respiratory Syncytial Virus (RSV) vaccine candidate that will be advanced into additional preclinical studies to support an Investigational New Drug (IND) applicati...

Palkion Selects Novel Oral Development Candidate for the Treatment of Anemia

SAN DIEGO, June 29 /PRNewswire/ -- Palkion, Inc. announced today that it has initiated preclinical development studies for its orally available anemia therapeutic candidate that modulates the Hypoxia-Inducible Factor Prolyl Hydroxylase (HIF-PH) enzyme system. In February 2008, Palkion was founded ...

Novavax and the NIH Agree to Evaluate a Virus-like Particle (VLP) Vaccine Candidate Against the Novel Influenza A (H1N1) Virus

Company completes initial steps towards producing Influenza A (H1N1) VLP vaccine for animal and human testing ROCKVILLE, Md., June 4 /PRNewswire-FirstCall/ -- Novavax, Inc. (Nasdaq: NVAX ) and the Division of Microbiology and Infectious Diseases (DMID) of the National Institute of Allergy a...

Trubion Announces Acceptance of Three Presentations on Its TRU-016 Product Candidate at the 2009 ASCO Annual Meeting

Phase 1: Encouraging Results Observed in CLL Patients Treated With Low Doses of TRU-016 Preclinical Efficacy: TRU-016 is Additive or Synergistic in Combination with Established Therapeutics Preclinical Mechanism Apoptosis in CLL Cells Occurs Via Distinct Mechanism Compared With Other Th...

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Candidate in Biological Products

Rabbit Anti-Human ALS2CR2 Polyclonal Antibody, Unconjugated from Proteintech Group, Inc.

Description:... amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2...
Company:Proteintech Group, Inc.

Mouse Anti-Human ALS2CR8 Polyclonal Antibody, Unconjugated from Novus Biologicals

Description:... Mouse polyclonal antibody to ALS2CR8 - amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8...
Company:Novus Biologicals

Rabbit Anti-BMP2 Polyclonal Antibody, Unconjugated from GeneTex

Description:...polyclonal to BMP2 BMP2 belongs to the transforming growth factor beta (TGFB) superfamily. Bone morphogenic protein induces bone formation. BMP2 is a candidate gene for the autosomal dominant disease of fibrodysplasia (myositis) ossificans progressiva. Immunogen: Synthetic peptide: PSDEVLSEFELRLLSM conjuga...
Company:GeneTex

Anti-Cyclin D2 (G1-phase Cyclin) Ab-2 Monoclonal Antibody, Unconjugated from Lab Vision

Description:... Cyclin D2 is a G1 cyclin required for G1-phase progression and is a strong candidate for a proto-oncogene. cyclin D2 can phosphorylate pRB when associated with cdk4 and/or cdk6. Species Reactivity: Human, Mouse, and Rat. Others-not ...
Company:Lab Vision

MIDAS TRAQ System with 4000 Q TRAP LC/MS/MS System from Applied Biosystems

Description:...peptide standards, for each potential biomarker. Quantitatively Validate candidate Biomarkers without Western Blots or Immunoassays After candidate verification, the resulting assays can be used to quantitatively validate t...
Company:Applied Biosystems

Hummingbird for Compound Library Management from Genomic Solutions

Description:... The new Hummingbird has the ability to quickly and accurately copy or reformat a compound storage plate makes it a perfect candidate for inclusion in these high speed stores. Hummingbird utilizes a simple OCX interface supplied with all the Cartesian products to allow integration in...
Company:Genomic Solutions

Candidate in Biological Definition

Fitness landscape

...ues is then called a fitness landscape. In evolutionary optimization problems, fitness landscapes are evaluations of a fitness function for all candidate solutions (see below). The idea to study evolution by visualizing the distribution of fitness values as a kind of landscape was first introduced by...

Candidate in Biological Dictionary

Untranslated region

...effect of the 5' untranslated region ... ... based predictions of secondary structure of the 3' untranslated region (UTR) ... 4 vaccine candidate with a 30 nucleotide deletion in its 3'- untranslated region . ... ... the 5'- untranslated region (-575) of the p27 gene and (b) the a...

Run-off

... Professional Computer Consultants ... Zimbabwe's president Robert Mugabe was sworn in for his sixth term on June 29, 2008. Robert Mugabe, the only candidate still in the race, won a run - off election for ... that can be used by marinas to reduce pollutants associated with storm water run - off . ......

Quantitative trait loci

...influenced by multiple genes. ... Mapping of quantitative trait loci . candidate gene. Genetic association. Introgression ... What Is A Quantitative T..., the free encyclopedia ... Heritability · Quantitative trait locus · candidate gene · Effective population size ... The nature and identification o...

Positional cloning

...jor reason that positional cloning is moving from the "perditional to ... the same time, standard positional cloning efforts usually result in candidate ... There are two stages in the process of positional cloning . ... mapping and positional cloning have filled entire ... 10.3.1 Prerequis...

Peripheral protein

...e ... Names and origin · Protein attributes · General annotation (Comments) ... "The gene for the peripheral myelin protein PMP-22 is a candidate for Charcot ... ... clone:F830008I05 product: peripheral myelin protein , full insert sequence, GAS ... length enriched library, clone: 26100...

Neural tube

...ore a woman ... This is the neural tube , the precursor of the brain and spinal cord. ... Genome-Wide Screen for Neural Tube Defects Reveals candidate Genes on ... Article: Folic acid supplementation for the prevention of neural tube defects: ... ...