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Calcitonin in Medical News

While Some New Agents Will Achieve Strong Sales, the Migraine Drug Market Will Decline $1.3 Billion by 2018 as Generic Erosion Takes Toll on Top-Selling Brands

...he overall migraine market during the next decade and will exert increasing pressure on new products. However, the emergence of Merck's first-in-class calcitonin gene-related peptide receptor antagonist telcagepant as an alternative to triptan therapy will help counteract market losses -- according to the repor...

Par Pharmaceutical Begins Shipment of Generic Miacalcin(R)

...onin-salmon nasal spray should be reserved for patients who refuse or cannot tolerate estrogens or in whom estrogens are contraindicated. Because calcitonin is a polypeptide, the possibility of a systemic allergic reaction exists. Please read full prescribing information available at www.parpharm.co...

New Migraine Drug Shows Promise

...ease, high blood pressure and certain migraine subtypes, according to a news release about the study. Telcagepant is from a different class, called calcitonin gene-related peptide (CGRP) antagonists. It's believed that brain concentrations of CGRP are elevated during a migraine. CGRP antagonists don't seem t...

Many Osteoporosis Medications Prevent Fractures, But None Is Proven Best

...ronate (Didronel), ibandronate (Boniva), pamidronate (Aredia), risedronate (Actonel) and zoledronic acid (Zometa). The report also looked at estrogen, calcitonin (a man-made hormone), calcium, vitamin D, testosterone, parathyroid hormone and selective estrogen receptor modulators (SERMs). Not enough scienti...
Calcitonin in Medical Technology

Emisphere Announces Recruitment of Novartis Phase III Study for Oral Osteoporosis Treatment

...Study to Explore the Effects of Eligen(R) Delivery Technology and Salmon calcitonin on Vertebral Fractures in Postmenopausal Women CEDAR KNOLLS, N.J., Aug. 5... a multi-center Phase III study exploring the safety and efficacy of Salmon calcitonin and Emisphere's proprietary Eligen(R) Technology in the treatment of verteb...

Exelixis Reports Encouraging Phase 1 Data for XL184 at ASCO

... of 17) experiencing partial responses. With a single exception, all of the evaluated MTC patients had reductions in the MTC-associated plasma markers calcitonin and carcinoembryonic antigen. Most of the MTC patients in the trial had previously failed other treatments, including tyrosine kinase inhibitors with ...

Genta Clinical Programs Featured at American Society of Hematology Meeting

...tients with cancer-related hypercalcemia who were resistant to hydration, randomized double-blind trials have been conducted with Ganite compared with calcitonin and with two bisphosphonates (etidronate [Didronel(R); Proctor and Gamble] and pamidronate [Aredia(R); Novartis, Inc.]). G4544 was developed to enab...

Genta Completes Initial Clinical Dosing of G4544, a New Oral Drug for Bone Diseases

...tients with cancer-related hypercalcemia who were resistant to hydration, randomized double-blind trials have been conducted with Ganite compared with calcitonin and with two bisphosphonates (etidronate [Didronel(R); Proctor and Gamble] and pamidronate [Aredia(R); Novartis, Inc.]). G4544 was developed to enabl...

Emisphere Technologies, Inc. Announces 2007 Third Quarter Financial Results

...lts progression of the illness rather than treating symptoms -- Both products use Emisphere's eligen(R) delivery technology to provide salmon calcitonin for the first time as a convenient oral medication Emisphere has three products in Phase II: -- Development of recombinant human growth hormone ("...

Genta Initiates First Clinical Trial with New Oral Drug (G4544) to Treat Bone Disease

...tients with cancer-related hypercalcemia who were resistant to hydration, randomized double-blind trials have been conducted with Ganite compared with calcitonin and with two bisphosphonates (etidronate [Didronel(R); Proctor and Gamble] and pamidronate [Aredia(R); Novartis, Inc.]). About G4544 G4544 was devel...

Emisphere Technologies, Inc. Announces 2007 Second Quarter Financial Results

...lts progression of the illness rather than treating symptoms -- Both products use Emisphere's eligen(R) delivery technology to provide salmon calcitonin for the first time as a convenient oral medication Emisphere has three products in Phase II: -- Development of recombinant human growth hormone ("r...

Merck's Investigational Migraine Treatment MK-0974 Significantly Improved Migraine Pain on Several Efficacy Measures in a Phase II Study

... from a Phase II study presented for the first time at the American Headache Society (AHS) annual meeting showed that MK-0974, an investigational oral calcitonin gene-related peptide (CGRP) receptor antagonist, significantly improved migraine pain relief two hours after dosing compared to placebo, and the relie...
Calcitonin in Medical Products

Nichols Advantage® Calcitonin Assay

Description: Fully automated Chemiluminescence assay for the measurement of calcitonin hormone in serum....
Company:Nichols Institute Diagnostics

Calcitonin IRMA Test

Description:... calcitonin is synthesized in the parafollicular C-cells of th...ackaged in secretory granules. The major action of calcitonin is to lower plasma calcium concentrations, by inhi...nistration of calcitonin. Exogenously administered calcitonin has also been shown to reduce pain associated with...
Company:Diagnostic Systems Laboratories, Inc.

Calcitonin ELISA

Description:... The calcitonin ELISA is intended for the quantitative determination of calcitonin in human serum....
Company:MD Biosciences

Calcitonin Assay Immunoradiometric (IRMA) Assay

Description:... The Scantibodies calcitonin Immunoassay is a two-site immunoradiometric assay ... Two different goat polyclonal antibodies to human calcitonin have been purified by affinity chromatography to be specific for well-defined regions on the calcitonin molecule. For the quantitative determination of...
Company:Scantibodies Laboratory, Inc.

Calcitonin, Ultra-Sensitive RIA Test

Description:... calcitonin is synthesized in the parafollicular C-cells of th...ackaged in secretory granules. The major action of calcitonin is to lower plasma calcium concentrations, by inhi...nistration of calcitonin. Exogenously administered calcitonin has also been shown to reduce pain associated with...
Company:Diagnostic Systems Laboratories, Inc.

Calcitonin RIA Test

Description:... calcitonin is synthesized in the parafollicular C-cells of th...ackaged in secretory granules. The major action of calcitonin is to lower plasma calcium concentrations, by inhi...nistration of calcitonin. Exogenously administered calcitonin has also been shown to reduce pain associated with...
Company:Diagnostic Systems Laboratories, Inc.

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Calcitonin in Medical Definition

Proteopathy

...s β2-microglobulin Inclusion body myopathy/myositis Amyloid β peptide (Aβ) Cataracts Crystallins Medullary thyroid carcinoma calcitonin Cardiac atrial amyloidosis Atrial natriuretic factor Pituitary prolactinoma Prolactin Hereditary lattice corneal dystrophy Ker...
Calcitonin in Medical Dictionary

Calcitonin

Calcitonin is a 32-amino acid linear polypeptide hormone that is produced in humans primarily by the parafollicular cells of the thyroid, and in many other animals in the ultimobranchial body. It acts to reduce blood calcium... calcitonin n. A peptide hormone, produced by the thyroid ...

PTH

... the parathyroid glands as a polypeptide containing 84 amino acids. It acts to increase the concentration of calcium (Ca2+) in the blood, whereas calcitonin of the... Port Huron (Amtrak station), Michigan, United States; Amtrak station code PTH ... Retrieved from "http://en.wikipedia.org /wik...
Calcitonin in Biological Technology

Emisphere Announces Recruitment Phase III Study for Oral Osteoarthritis Treatment

...II Study to Explore the Effects of Oral Calcitonin, a combination of Salmon calcitonin and Eligen Delivery Technology on Knee Osteoarthritis Treatment CEDAR KNO...II study exploring the safety and efficacy of an oral formulation of salmon calcitonin using Emisphere's proprietary Eligen Technology to treat patients with oste...

U.S. Clinicians Indicate a Strong Need for New Tools to Combat Sepsis

.../www.biomerieux.com or http://www.biomerieux-industry.com (1) Muller B, Becker KL, Schachinger H, Rickenbacher, PR, Huber PR, Zimmerli W, Ritz R. calcitonin precursers are reliable markers of sepsis in a medical intensive care unit. Crit Care Med 2000;28:977-983. ...

Michael V. Novinski, Emisphere President/CEO Featured in the Wall Street Transcript

...development]." Through this program, "by the middle of this year, more than 5,000 patients will be taking Emisphere's eligen(R) technology with Salmon calcitonin for the treatment of osteoarthritis and osteoporosis," explained Mr. Novinski. "That's very exciting." The entire Wall Street Transcript interview c...

Emisphere Technologies, Inc. Announces 2008 First Quarter Financial Results

...Emisphere has two Phase III product candidates based on the compound salmon calcitonin in collaboration with Novartis Pharma AG and its development partner, Nordi... candidates use Emisphere's eligen(R) delivery technology to provide salmon calcitonin as a convenient oral medication. There will be over 5000 patients enrolled ...

Emisphere Technologies, Inc. Announces 2007 Fourth Quarter and Year End Financial Results

...Emisphere has two Phase III product candidates based on the compound Salmon calcitonin in collaboration with Novartis Pharma AG and its development partner, Nordi... candidates use Emisphere's eligen(R) delivery technology to provide Salmon calcitonin as a convenient oral medication. Emisphere has two product candidates in ...

Unigene Restates Policy on Analyst Reports

...ene is targeting its initial efforts on developing calcitonin and PTH-based therapies. Fortical(r), Unigene's nasal calcitonin product for the treatment of postmenopausal osteop...gy to GlaxoSmithKline and worldwide rights for its calcitonin manufacturing technology to Novartis. Unigene's pa...

Stonegate Report About Unigene Laboratories Inc.

...erapeutic peptides. Its initial focus is on salmon calcitonin (sCT) and other peptides for the treatment of chro...ine (NYSE: GSK ) and the worldwide rights for its calcitonin manufacturing technology to Novartis Pharma AG (NY...s also initiated a Phase III trial evaluating oral calcitonin against osteoporosis, which utilizes UGNE's manufa...

The development of a calcitonin-gene related peptide (CGRP) receptor-binding assay using the LEADseeker Multimodality Imaging System

...in (WGA) PS RPNQ0260 LEADseeker SPA Imaging Beads (2-[125I]iodohistidyl10) calcitonin gene- IM184 related peptide (CGRP)

Other material r...

Calcitonin in Biological Definition

Hormone

...nd angiotensin antidiuretic hormone (ADH, also vasopressin, arginine vasopressin, AVP) atrial-natriuretic peptide (ANP, also atriopeptin) calcitonin cholecystokinin (CCK) corticotropin-releasing hormone (CRH) erythropoietin ( EPO ) follicle stimulating hormone (FSH) gastrin ...
Calcitonin in Biological Dictionary

Polypeptide

... 4.3 Pancreatic polypeptide -related peptides. 4.4 Opioid peptides. 4.5 calcitonin peptides ... A polypeptide is a single linear chain of amino acids. ... Amylin, or Islet Amyloid Polypeptide (IAPP), is a 37-residue pepti...
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