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Cadherin in Medical News

A potential molecular target for biotherapy esophageal squamous cell carcinomas

... The cadherin superfamily has a correlate relationship with the invasion and metastasis of carcinoma. It has been suggested that, unlike E-cadherin, N-cadherin may ...
Cadherin in Medical Technology

Autism Genes Discovered; Help Shape Connections Among Brain Cells

...articular region of chromosome 5. That region is located between two genes, cadherin 9 (CDH9 ) and cadherin 10 ( CDH10 ), which carry codes to produce neuronal cell-adhesion molecules...

NIDA Study Identifies Genes That Might Help Some People Abstain from Smoking

...Genes that harbor variants that contribute to both success in quitting smoking and in vulnerability to become dependent on multiple substances include cadherin 13 (a molecule involved in cell adhesion, which governs how cells recognize and connect to their neighbors) and a cyclic G-dependent protein kinase ge...
Cadherin in Biological News

Mayo: Variants in gene on X chromosome associated with increased susceptibility to Alzheimer's

...e association and the degree of risk it confers on developing Alzheimer's disease." PCDH11X encodes a protocadherin that is included in a family of cadherin molecules that promote cell-cell adhesion and signaling in the central nervous system. Some evidence suggests that protocadherins are processed by pre...

Mayo researchers identify dangerous 'two-faced' protein crucial to breast cancer spread and growth

...are membrane proteins that help cells stick to each other to form a tissue. On the outside of a cell's membrane, they act like Velcro, fusing to other cadherin proteins on adjacent cells. On the inside, they latch on to a chainwork of catenins, which are proteins that regulate a cell's shape and function. The...

Genome of marine organism tells of humans' unicellular ancestors

...nt of multicellularity, but they have 23 genes for cadherin proteins, about the same as the fruit fly or the m... animals (including humans) employed these ancient cadherin proteins to bind and eat bacteria, while more comp...they have no immune system; collagen, integrin and cadherin domains, though they have no skeleton or matrix bi...

NIDA study identifies genes that might help some people abstain from smoking

...Genes that harbor variants that contribute to both success in quitting smoking and in vulnerability to become dependent on multiple substances include cadherin 13 (a molecule involved in cell adhesion, which governs how cells recognize and connect to their neighbors) and a cyclic G-dependent protein kinase ge...

Two-faced protein can stop metastasis or promote it, researchers say

...looks at how p120 catenin interacts with different cadherin cell adhesion proteins in cancer cells. cadherin proteins go through a cell membrane, and on the outside, they act like Velcro, sticking to other cadherin proteins on adjacent cells. On the inside of the ...
Cadherin in Biological Technology

The closest look ever at native human tissue

...l-Amoudi, who carried out the work in Frangakis lab. The trick is that each cadherin binds twice: once to a molecule from the juxtaposed cell, and once to its n...establishes very tight contacts between cells. The new insights into the cadherin system broadens the understanding of structural aspects of cell adhesion an...

New designer toxins kill Bt-resistant insect pests

... based on understanding a receptor molecule called cadherin on the insects' gut membranes. Normal cadherin binds with the Bt toxin in a lock-and-key fashion....ic changes, mutations, that change the lock. Their cadherin no longer takes the key." The UNAM team did an...
Cadherin in Biological Definition

Transmembrane protein

...ic sequences . Examples Some cell adhesion proteins Some receptor proteins Glycophorin Insulin receptor GLUTI Integrin cadherin See also : membrane topology , transmembrane helix , membrane protein ...
Cadherin in Biological Dictionary

Intercalated disc

... intercalated disc of adult cardiac muscle consists of three main junctional ... This suggests that the intercalated disc was saturated with cadherin protein in ... Stacked images of intercalated discs were traced with IPLab ... Immunoblotting of intercalated disc -associated proteins ...
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(Date:10/14/2014)... A new study published in Cancer Research ... liver and colon cancers—can promote the development of skin ... proliferation and survival of sun-damaged skin cells. , Previously ... seven proteins called sirtuins that help regulate genomic stability ... aging. SIRT6 helps repair DNA damage, which can lead ...
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