Leaders from the Field of Pain Therapeutics to Discuss Latest Discoveries and Breakthroughs at Arrowhead's 3rd Annual Pain Therapeutics Summit
...elopments in recent years in the field, including new research in sodium channel blockers (TRPV1 and TRPA1), late-stage clinical advances with Merck's cgrp
antagonist program, new research in biologic therapies, the genetics of pain, abuse-resistant opioids, analysis of FDA's REMS program and a plethora o...
New Migraine Drug Shows Promise
...onists. It's believed that brain concentrations of cgrp
are elevated during a migraine. cgrp
antagonists don't seem to have blood vessel narrow...zolmitriptan.
"One potential benefit of the new cgrp
receptor antagonist class of acute migraine treatm...
Getting Ready Corporation and Winston Laboratories, Inc. Announce Merger Agreement
...neuropeptides, substance P (SP)
and calcitonin-gene related peptide (CGRP). Pain transmission is then
diminished by the subsequent depletion of SP and cgrp
from the neuron,
coupled with suppression of the synthesis and transport of neuropeptides
along the neuron. This press release contains "forward-look...
Excessive RAMP1 Protein may Cause Migraines
... a neuropeptide.
The neuropeptide is called cgrp
(calcitonin gene-related peptide) and studies have...s a key role in migraine headaches. In particular, cgrp
levels are elevated in the blood during migraine, and drugs that either reduce the levels of cgrp
or block its action significantly reduce the pain ...