Genes Play Part in Prostate Cancer Among Races

... with a more than a 50 percent increased risk of prostate cancer. This effect was not seen in Hispanic men. Among Hispanic white men, a combination of cdx2 and V89L was associated with a more than threefold increased risk of prostate cancer. This link was not seen in white men. The findings, published ...

CDX2 in Biological News

Genes may play role in risk assessment for prostate cancer among Hispanics and caucasians

...kI was associated with a more than 50 percent increased risk of prostate cancer. This effect was not seen in Hispanic men. Among Hispanic white men, cdx2 and V89L in combination were linked with a more than three-fold increase in prostate cancer. However, this interaction was not seen in Caucasian men. ...

Study uncovers clues to cystic fibrosis gene dysfunction and gastrointestinal disease

...ones, they conducted further tests which linked this process to active intestinal CFTR expression and occupation by regulatory factors known as HNF1a, cdx2 and Tcf4. The combined activity of these factors appears to modify the architecture of chromatin, the form in which DNA is packaged in the cell, leadi...

Researchers offer proof-of-concept for Altered Nuclear Transfer

...eate a blastocyst that cannot implant in a uterus, the researchers disabled cdx2 in mouse cells. They accomplished this with a technique called RNA inte... However, once the stem cells had been extracted from the blastocysts, cdx2 was still disabled in each of these new cells, something that needed to be ...

CDX2 in Biological Products

Mouse Anti-CDX-2 Monoclonal Antibody, Unconjugated, Clone CDX2-88 from BioGenex

Description:...enotype of differentiated villus enterocytes as well as in the maintenance of the phenotype. Clone CDX2-88 reacts with a conserved epitope of the 40kD cdx2 protein localized in the nucleus. It exclusively marks nuclei of colonic epithelial cells and colorectal cancers on formalin-fixed, paraffin-embedded ...
Company:BioGenex