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Bupropion in Medical News

-Contrave(R) Obesity Research Phase 3 Program Meets Co-Primary and Key Secondary Endpoints; Exceeds FDA Efficacy Benchmark for Obesity Treatments-

...ways in the brain that impact one's ability to initiate and sustain weight loss." (1) Contrave32 is a proprietary fixed-dose combination of bupropion SR 360mg/naltrexone SR 32mg. References to Contrave16 and Contrave48 relate to combinations containing naltrexone SR 16mg or naltrexone SR 48mg, resp...

Preliminary report on antidepressants published

...nefit of three agents, reboxetine, mirtazapine and bupropion XL in adult patients with depression, according to... of benefit The search identified 6 trials on bupropion XL (up to 300 mg/d) and the Institute was given ac...rm. The only antidepressant that was compared with bupropion XL in trials was venlafaxine XR....

Doctors Urged to Get Aggressive to Help Smokers

...ve pulmonary disease (COPD). They were randomly assigned to use a nicotine patch for 10 weeks or a combination of a patch, a nicotine oral inhaler and bupropion for as long as required. After six months, about 35 percent of those in the combination therapy group had quit smoking, compared with 19 percent of th...

Aplenzin(TM), the Only Single Tablet Once-Daily Treatment for Depression at All Doses, Now Available in the United States

...drobromide) extended-release tablets, an effective bupropion therapy for the treatment of major depressive diso...r. Aplenzin differs from other generic and branded bupropion antidepressants because it provides a unique HBr s...nly requires one tablet, once a day at the highest bupropion dose. This provides a simple, convenient option f...

GlaxoSmithKline Consumer Healthcare to Reach 85 Percent of the World's Smokers with Quit Aids

...e Library, Issue 1, 2004. Chichester, UK: John Wiley & Sons, LTD. (5) NICE. 2002. Guidance on the use of nicotine replacement therapy (NRT) and bupropion for smoking cessation. Technology Appraisal Guidance - No.39. (6) Centers for Disease Control and Prevention. Use of FDA-approved pharmacologic tre...

Zoloft, Lexapro the Best of Newer Antidepressants

... reviewed 117 studies that included more than 25,000 patients with major depression to come to this conclusion. The drugs tested in the trials were bupropion (Wellbutrin/Zyban), citalopram (Celexa), duloxetine (Cymbalta), escitalopram, fluoxetine (Prozac), fluvoxamine (Luvox), milnacipran (Savella), mirtaza...

Walmart Offers $9 Smoking Cessation Starter Pack

...owest price on the market.* The $9 starter pack of bupropion ER 150mg, the generic equivalent of Zyban, is now ...r $9 at Walmart may help reverse this trend as the bupropion ER starter pack - initiated at the request of both... double quitting success rates. In addition to the bupropion ER starter pack, Walmart also currently offers the...

Quitting Smoking Tougher on Women

...al options such as a nicotine patch, gum lozenge or inhaler can reduce nicotine cravings and double your chances of quitting. Antidepressants, such as bupropion (Wellbutrin, Zyban) or varenicline (Chantix), can also help decrease nicotine withdrawal symptoms, the news release said. Seek counsel: A tobacco ...

December 2008 Mayo Clinic Women's HealthSource Highlights Happiness, Dementia and Smoking

...ances of quitting. Options include a nicotine patch, gum lozenge, inhaler or nasal spray, which can reduce nicotine cravings. Antidepressants, such as bupropion (Wellbutrin, Zyban), or varenicline (Chantix), a medication that acts on the brain's nicotine receptors, can decrease nicotine withdrawal symptoms. ...

Actavis Receives Approval of Generic Wellbutrin XL(R) 150mg in the U.S.

...as received approval from the U.S. Food & Drug Administration to market bupropion Hydrochloride extended-release tablets (XL) 150mg. Distribution of the product has commenced. bupropion Hydrochloride extended-release tablets (XL), available in 150 & 300mg s...
Bupropion in Medical Technology

Orexigen(R) Therapeutics Presents Data on Its Proprietary Formulation of Naltrexone Sustained Release (SR) Used in Contrave(R)

...nteers randomized to either naltrexone SR 37.5mg / bupropion SR 270mg or naltrexone IR 36mg / bupropion SR 270mg. Patients were treated for up to 14 days. Naltrexone SR / bupropion SR patients spontaneously reported fewer GI advers...

Orexigen(R) Initiates Second Phase IIb Empatic(TM) Trial on Schedule

...he body's burning of calories and sustaining weight loss. The Company's other late-stage obesity product candidate, Contrave(R), is a combination of bupropion SR and naltrexone in a proprietary SR formulation that also appears to result in improved tolerability compared to the legacy naltrexone IR formulatio...

Study Sheds Light on Medication Treatment Options for Bipolar Disorder

...people are excluded from participating if they have co-existing disorders. Before participants were randomized to one of two antidepressants — bupropion (Wellbutrin) or paroxetine (Paxil) — or to a placebo, doctors trained in the treatment of bipolar disorder adjusted participants mood stabilizer...

Orexigen Therapeutics to Present Data on Contrave Impact on Visceral Fat and Insulin Resistance at American Diabetes Association 67th Scientific Sessions in Chicago June 23

... Insulin-Resistance." Contrave is a proprietary fixed dose combination of bupropion SR (sustained release) and Orexigen's novel formulation of naltrexone SR in... demonstrated statistically significant weight loss at 24 weeks compared to bupropion SR alone, naltrexone IR (immediate release) alone, and placebo. Contrave is...
Bupropion in Biological News

New genetic research into nicotine addiction shows promise for personalized treatment

...nown to metabolize both the smoking cessation drug bupropion and nicotine is highly genetically variable in all...icipants were then provided with either placebo or bupropion treatment for ten weeks and followed up for 6 mont...with a specific variant of the gene benefited from bupropion treatment and maintained abstinence longer while d...

In SAD patients, autumn antidepressants can prevent winter depression

...ough pre-emptive treatment with the antidepressant bupropion extended release tablets. One group of patients w.... The relapse rate was 16% for patients taking bupropion extended release compared with 28% for those takin... well tolerated. When the patients stopped taking bupropion extended release in the spring, there was no incre...
Bupropion in Biological Technology

Orexigen(R) Therapeutics Presents Additional NB-302 Contrave(R) Data at American Diabetes Association (ADA) 69th Scientific Sessions

...ontrolled trial, conducted in 793 patients at nine U.S. centers. The trial evaluated the additional weight loss of Contrave (32mg naltrexone SR/360mg bupropion SR) when added to an intensive behavior modification program consisting of counseling, diet and exercise. The co-primary endpoints were percent chang...

Orexigen(R) Therapeutics Announces Upcoming Data Presentations at American Diabetes Association and Endocrine Society Annual Scientific Meetings

...edicine, Philadelphia, PA Title: "Naltrexone + bupropion Combination Causes Significant Weight Loss: A ...dicine, Philadelphia, Pa. Title: "Naltrexone + bupropion Combination Causes Weight Loss and Improves Qu...icine, St. Louis, Mo. Title: "Naltrexone + bupropion Combination Causes Significant Weight Loss Wit...

Orexigen(R) Therapeutics Announces First of Four Phase 3 Trials of Contrave(R) Meets Co-Primary and Key Secondary Endpoints

...56-week, double-blind, placebo-controlled trial conducted at nine U.S. centers evaluated the efficacy and safety of Contrave (32mg naltrexone SR/360mg bupropion SR) compared to placebo in 793 obese patients who participated in an intense behavioral program consisting of counseling, diet and exercise. Patients...

Orexigen(R) Therapeutics Issued a Key Fourth U.S. Patent on Contrave(R)

...ley composition patent (U.S. Patent No. 7,375,111) which was issued by the USPTO in May 2008 and broadly covers sustained release (SR) compositions of bupropion and naltrexone combined in a single dosage form. The Weber/Cowley methods patent will provide protection for Contrave through mid 2024. "The is...

Orexigen(R) Therapeutics Announces Third Quarter 2008 Financial Results

... patent will broadly cover methods of treating obesity with combinations of bupropion and naltrexone, the two active agents in Contrave, through mid 2024. It is ... which was issued by the USPTO in May 2008, which covers SR compositions of bupropion and naltrexone combined in a single dosage form through March 2025. Upon is...

Orexigen Therapeutics Announces Multiple Data Presentations at The Obesity Society Annual Scientific Meeting

... a Dose Optimization Study with Zonisamide SR and bupropion SR" Time: 11:00-11:15 a.m. MT Poster Presentati... a Dose Optimization Study with Zonisamide SR and bupropion SR" Time: 12:45-2:45 p.m. MT Poster Presentatio... a Dose Optimization Study with Zonisamide SR and bupropion SR" Time: 12:45-2:45 p.m. MT Upcoming Corporate...

Actavis Receives Approval of Generic Wellbutrin SR(R) and Zyban(R) Tablets in the U.S.

...from the U.S. Food & Drug Administration to market bupropion Hydrochloride extended-release tablets (SR). Distr...ution of the products will commence immediately. bupropion Hydrochloride extended-release tablets (SR), avail...ding December 2007 according to IMS Health data. bupropion Hydrochloride extended-release tablets (SR), avail...

Watson Pharmaceuticals Reports Fourth Quarter and Full Year 2007 Results; Provides 2008 Outlook

....7 million, primarily related to the loss of revenue from oxycodone HCl controlled-release tablets. This was offset by new product launches in 2007 of bupropion hydrochloride extended-release 300mg, fentanyl transdermal patch, and Tilia(TM) Fe. Generic other revenue increased $21.5 million to $30.2 million, ...
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(Date:9/30/2014)... Journal of Medicine reports positive results of a ... the subset of lung cancer marked by rearrangement of ... patients with advanced non-small cell lung cancer testing positive ... percent, with 3 complete responses and 33 partial responses. ... the disease to resume its growth after being slowed ...
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