botulinum

American Academy of Dermatology Responds to FDA Decision Regarding Botulinum Toxin Products

SCHAUMBURG, Ill., April 30 /PRNewswire-USNewswire/ -- The American Academy of Dermatology (Academy) today issued a statement in response to the U.S. Food and Drug Administration's (FDA) announcement that a box warning will be added to the labeling of botulinum toxin products and a medication guide...

Uses for Botulinum Toxin — A Miracle Poison — Continue to Grw

First, it was infamous as a deadly form of food poison. Then, fame came as a temporary remedy for wrinkles. Now, botulinum toxin is considered the 'miracle poison' and used for an increasing number of medical conditions. // The December issue of Mayo Clinic Health Letter covers how this drug ...

Highly-Concentrated Botulinum Preparation Can Result in Severe Illness

An examination of 4 cases of botulism following cosmetic injections to the face indicates that the adults received a highly concentrated, //unlicensed preparation that resulted in toxin levels up to 40 times the estimated human lethal dose, according to a report. Botulism is a rare paralytic i...

Appearance Of Facial Scars Improved By Botulinum Toxin

Researchers from Mayo Clinic have reported improved appearance of scars following injection with botulinum toxin (BOTOX?) early after// the occurrence of a wound. The injection prevents muscle movement from wrinkling the wound site by paralyzing the region thus creating a smooth surface for ...

Dysport proves safe, effective anti-wrinkle treatment, UT Southwestern plastic surgeons find

...ng for African-American patients; Less effective for people 65 and older; and As effective for those who had previously been injected with a form of botulinum neurotoxin type A (such as Botox). The Food and Drug Administration-approved study involved 816 participants with moderate to severe frown lines (...

Photos: Don't Let Them See You Sweat This Summer

...xpressed in "Units" or "U" are different among the botulinum toxin products; clinical doses expressed in units are not interchangeable from one botulinum toxin product to another. Be alert to and e... potential adverse events due to distant spread of botulinum toxin effects following local injections including...

DOR BioPharma Appoints Christopher P. Schnittker, CPA, as Vice President of Administration and Controller

.... DOR's biodefense products in development are recombinant subunit vaccines designed to protect against the lethal effects of exposure to ricin toxin, botulinum toxin and anthrax. DOR's ricin toxin vaccine, RiVax(TM), has been shown to be well tolerated and immunogenic in a Phase 1 clinical trial in normal vol...

New Survey Reveals High Expectations for Popular Aesthetic Injections

...respondents were interested in receiving aesthetic botulinum toxin injections within the next six months.(1) ...ar interest, many expressed reluctance to having a botulinum toxin injection. In fact, one-third of those who ...rvey respondents who would ever consider receiving botulinum toxin injections cited that a guarantee of natural...

Look Great this Summer, Phoenix! BOTOX and Juvederm Offered at Beauty Open House with Dr. Heidi Regenass, June 25th

...ays Dr. Regenass. With Dr. Regenass’ patients in Phoenix, BOTOX Cosmetic is very popular and produces results. The product is made of the botulinum toxin and is completely safe if administered properly, by an experienced and certified plastic surgeon. The product works by relaxing the muscles...

Dysport Added as a Procedure on AmericanHealthandBeauty.com: Let the Wrinkle Wars Begin

...cedure now, staying ahead of the curve. Dysport uses a purified form of botulinum toxin type A, which when used in the appropriate dosage, temporarily paraly... approved drug of its type to compete with BOTOX (TM), which also uses the botulinum toxin. Jeffrey Adelglass, M.D., F.A.C.S., a cosmetic physician and Medical...

botulinum in Medical Technology

DOR BioPharma Announces Publication Describing Results of Its Multivalent Botulinum Toxin Vaccine BT-VACC

MIAMI--(MARKET WIRE) -- July 02, 2007 -- DOR BioPharma, Inc. (OTCBB: DORB) ("DOR" or the "Company") announced today that the first results from testing of a multivalent form of its botulinum toxin vaccine, BT-VACC™, have been published in the journal Infection and Immunity (Ravichandran et a...

DOR BioPharma Announces Issuance of European Patent for Its Oral Multivalent Botulinum Toxin Vaccine BT-VACC

MIAMI, FL -- (MARKET WIRE) -- July 06, 2007 -- DOR BioPharma, Inc. (OTCBB: http://studio.financialcontent.com/Engine?Account=iwire&PageName=QUOTE&Ticker=DORB">DORB...

Estrogen Getting Cool Reception From Dermatologists for Mixed Results in Improving Appearance of Skin

...y use to address the common signs of aging -- including retinoids, alpha-hydroxy acids and other topical therapies, as well as chemical peels, lasers, botulinum toxin and skin fillers, to name a few. "The best advice I can offer my patients to improve their overall skin health is to wear sunscreen with ...

Merz Pharmaceuticals Announce Three Studies of NT-201 - (Botulinum neurotoxin type A Free From Complexing Proteins)

...stracts: Efficacy and safety of NT-201 (Xeomin(R); botulinum neurotoxin type A free from complexing proteins) i...a patients, Efficacy and safety of NT-201 (Xeomin; botulinum neurotoxin type A free from complexing proteins) i...tients, and Repeated injections of NT-201 (Xeomin; botulinum neurotoxin type A free from complexing proteins) i...

DOR BioPharma Receives EMEA Agreement on the Design of its Confirmatory Phase 3 Clinical Trial of orBec(R) in GI GVHD

.... DOR's biodefense products in development are recombinant subunit vaccines designed to protect against the lethal effects of exposure to ricin toxin, botulinum toxin and anthrax. DOR's ricin toxin vaccine, RiVax(TM), has been shown to be well tolerated and immunogenic in a Phase 1 clinical trial in normal vol...

Merz Pharmaceuticals Announces Results of Clinical Trials with NT-201(Botulinum neurotoxin type A free from complexing proteins) at Annual Movement Disorders Society Meeting

...udies reaffirm our beliefs that NT-201 (Xeomin(R); botulinum neurotoxin free from complexing proteins), can be ... have shown non-inferiority of NT-201 to one other botulinum toxin in the treatment of cervical dystonia," said...acy and overall tolerability of NT-201 (Xeomin(R); botulinum neurotoxin free from complexing proteins) authored...

Merz Pharmaceuticals Announces Results of Three Clinical Trials With NT-201 (Botulinum Neurotoxin Type A Free From Complexing Proteins) in Movement Disorder Patients

...irs, Merz Pharmaceuticals, USA. NT-201 is a botulinum neurotoxin type A free from complexing proteins ap...en found to heighten the immune system response to botulinum toxin. "Xeomin - the proposed brand name for ...t Sinai Medical Center in New York and a leading botulinum neurotoxin researcher. The NT-201 data will...

DOR BioPharma, Inc. Executes $400,000 Equity Investment Agreement With Numoda Corporation

.... DOR's biodefense products in development are recombinant subunit vaccines designed to protect against the lethal effects of exposure to ricin toxin, botulinum toxin and anthrax. DOR's ricin toxin vaccine, RiVax(TM), has been shown to be well tolerated and immunogenic in a Phase 1 clinical trial in normal vol...

Got Pain?

... medications -- both oral and injectable -- (examples include Vitamin C and botulinum injections) have aided a hand surgeon's ability to combat these problems an...of the Hand (ASSH) is successfully using another type of injection therapy, botulinum Toxins on patients with nerve pain. The results of this type of less invasi...

Sanofi Pasteur Starts a Phase II Study of a Vaccine Against Clostridium Difficile

...y 60% of infants but only about 3% of healthy adults. It belongs to the Clostridium family of bacteria, which also includes C. tetani (tetanus) and C. botulinum (botulism). The C. difficile bacteria produce two potent toxins: A and B. When the natural microbial flora of the gut is disturbed, usually as a resul...

botulinum in Medical Products

Clostridium botulinum Culture

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Dysport® Clostridium Botulinum Type A

Description: Dysport is a simple, effective, non-surgical treatment that works by relaxing facial muscles on the forehead, thereby reducing and smoothing away frown-lines and wrinkles. Dysport is supported by over a decade of clinical experience. Dysport was developed in the United Kingdom in the early 1990s ...
Company:New Zealand Medical and Scientific Ltd

BOTOX® Cosmetic Botulinum Toxin Type A

Description: BOTOX® Cosmetic is a simple, nonsurgical, physician-administered treatment that can temporarily smooth moderate to severe frown lines between the brows in people from 18 to 65 years of age. It is the only treatment of its type approved by the Food and Drug Administration (FDA). BOTOX® Cosm...
Company:Allergan, Inc.

Myobloc®(Botulinum Toxin Type B) Injectable Solution

Description:... Myobloc (Botulinum Toxin Type B) Injectable Solution, the only botulinum Toxin Type B treatment available, has been demonstrated in numerous published studies to be safe and effective in treating cervical dystonia. Deliver...
Company:Solstice Neurosciences, Inc.

botulinum in Medical Definition

Forehead lift

... Paul, Malcolm D: Subperiosteal transblepharoplasty forehead lift: Aesth Plas Surg:Vol 20, No 2; March, 1996: 129-134; ^ Dyer WK Jr., Yung RT: botulinum toxin-assisted brow lift. Facial Plast Surg 2000 Aug; 8(3): 343-54 ^ Romo T 3rd, Sclafani AP, Yung RT: Endoscopic foreheadplasty: a histological...

botulinum in Medical Dictionary

Toxin

...e tunnel, called an ion ... Physician reviewed botulinum toxin type A patient information - includes botulinum toxin type A description, dosage and directions.... treated by heat or chemicals so that its ... botulinum toxin . ......

Spasticity

...s muscles and joints of the extremities, and is ... How to treat spasticity . Video lecture and latest research publications updated daily. ... botulinum toxin for spasticity in children with cerebral palsy: a ... Spasticity is an abnormal increase in muscle tone. ... Spasticity may increa...

Spasmodic dysphonia

... ... Spasmodic dysphonia is a neurologic disorder that science does ... Spasmodic ... Living with spasmodic dysphonia and injections of botulinum toxin-A ... Spasmodic dysphonia is a voice disorder resulting from involuntary ... Spasmodic dysphonia is a voice disorder resulting from ...

Infant botulism

... is a rare but serious paralytic illness caused by botulinum toxin, which is produced by the bacterium Clostrid...t can acquire botulism by ingesting Clostridium botulinum spores, which ... Infant botulism results from germination of swallowed spores of botulinum toxin ... Four cases of type B infant botulis...

Hand tremor

...tremors occur when your hand or affected body part is at rest. ... Also, botulinum toxin injections have been used for essential hand tremors . ... ...tremors occur when your hand or affected body part is at rest. ... Also, botulinum toxin injections have been used for essential hand tremors . ... L...

Clostridium

...er birds. Testing and treatment. ... Clostridium botulinum - The organism that causes botulism is common in...n. Read about botulism causes ( Clostridium botulinum toxin), symptoms (muscle paralysis, dry mouth, con... absorption of toxin produced by Clostridium botulinum that colonize the ... Clostridium ...

Botulism

... is a rare but serious paralytic illness caused by botulinum toxin, which is produced by the bacterium Clostrid...e... Read about botulism causes (Clostridium botulinum toxin), symptoms (muscle paralysis, dry mouth, con.... ... Wound botulism occurs when Clostridium botulinum spores contaminate a wound and produce toxin. .....

botulinum in Biological News

Scientists determine drug target for the most potent botulinum neurotoxin

UPTON, NY Botulinum neurotoxin responsible for the deadly food poisoning disease botulism and for the beneficial effects of smoothing out facial wrinkles can also be used as a dreaded biological weapon. When ingested or inhaled, less than a billionth of an ounce can cause muscle paralysis and e...

Genome of Clostridium botulinum reveals the background to world's deadliest toxin

The genome of the organism that produces the world’s most lethal toxin is revealed today. This toxin is the one real weapon in the genome of Clostridium botulinum and less than 2 kg — the weight of two bags of sugar — is enough to kill every person on the planet. Very small amounts of the same tox...

Molecular structure reveals how botulinum toxin attaches to nerve cells

WHAT: Botulism is a life-threatening disease caused by exposure to botulinum neurotoxins, which are among the most potent toxins known. These neurotoxins are produced by Clostridium botulinum, a bacterium found in soil and food. In the body, the toxins bind to and enter neurons, interfering with ne...

Highly concentrated botulinum preparation for cosmetic injections can result in severe illness

An examination of 4 cases of botulism following cosmetic injections to the face indicates that the adults received a highly concentrated, unlicensed preparation that resulted in toxin levels up to 40 times the estimated human lethal dose, according to a report in the November 22/29 issue of JAMA. ...

Researchers develop new ultrasensitive assay to detect most poisonous substance known

...ave developed a new ultrasensitive assay to detect botulinum neurotoxin. The toxin is one of the most poisonous... ( http://www.plosone.org/doi/pone.0002041 ). botulinum neurotoxin is produced by the bacterium Clostridiu...ly results when a person eats food tainted with C. botulinum bacteria or if a wound is infected by the bacteriu...

Encoded metallic nanowires reveal bioweapons

...t runs, Tok and his colleagues selected harmless model substances to stand in for anthrax spores, smallpox virus, and protein toxins such as ricin and botulinum toxin. If a simultaneous test for all of these is desired, the anthrax antibody would be attached to stripe pattern 1, the smallpox antibodies to stri...

Scientists develop a way to make the deadliest toxin known even more toxic

...IRM), and head of the laboratory that conducted the study, said, "Since the botulinum neurotoxin is the most poisonous toxin known, finding a compound to activat...zing dosage, reducing resistance, and increasing its clinical efficacy." botulinum neurotoxins are the most lethal poisons known. They produce progressive par...

Scientists reveal how deadly toxin hijacks cells

... Scientists have pinpointed exactly how botulinum neurotoxin A - a potential agent of biological war... may block the entry of toxins into cells." The botulinum toxins, of which there are seven types, are made b...rotein receptors that allow the different types of botulinum toxins into cells. "One goal at the Chapman labora...

Botox could help target resistant tumors for treatment

...vain in Brussels, Belgium, found that by injecting botulinum neurotoxin type A into two types of mouse tumors, ...response of tumors to radio- and chemotherapy." botulinum toxin is a naturally occurring molecule, and histo... Gallez and his colleagues hypothesized that since botulinum toxin impeded neurotransmitter release in the symp...

Tetanus toxin found to have therapeutic properties

..., and to slow the progress of neurodegenerative disorders such as Parkinson's disease. Tetanus toxin is a neurotoxin belonging to the same family as botulinum neurotoxins, which cause botulism. These have been successfully used as a therapy to treat disorders caused by abnormal muscular contractions such as ...

botulinum in Biological Technology

New Online Learning Tool Fills the Knowledge Gap on Botulinum Toxin Type B for Cervical Dystonia

Solstice Neurosciences, Inc. Launches a Self-Guided Lesson as Prep for In-Person Workshops MALVERN, Pa., Dec. 13 /PRNewswire/ -- In recognition that physician comfort and knowledge with techniques around botulinum toxin injections lead to the best results for patients...

Mentor Licenses Botulinum From WARF and Plans Wisconsin Manufacturing Facility

MADISON, Wis. - The Wisconsin Alumni Research Foundation (WARF) has completed a licensing agreement with Mentor Corporation a California-based publicly traded company (NYSE: MNT), which gives Mentor the exclusive manufacturing and marketing rights to the proprietary botulinum toxin technology ...

Clostridium botulinum

Multiporator / Electroporator 2510 Transformation Protocol Protocol No. 4308 915.509 12/2001 ...

Clostridium botulinum

Multiporator / Electroporator 2510 Transformation Protocol Protocol No. 4308 915.509 12/2001 ...

DOR BioPharma Receives FDA Orphan Drug Designation for orBec(R) for the Treatment of Chronic Gastrointestinal GVHD

.... DOR's biodefense products in development are recombinant subunit vaccines designed to protect against the lethal effects of exposure to ricin toxin, botulinum toxin and anthrax. DOR's ricin toxin vaccine, RiVax(TM), has been shown to be well tolerated and immunogenic in a Phase 1 clinical trial in normal vol...

DOR BioPharma Announces Issuance of European Patent for its LPM(TM) Oral Drug Delivery Technology

.... DOR's biodefense products in development are recombinant subunit vaccines designed to protect against the lethal effects of exposure to ricin toxin, botulinum toxin and anthrax. DOR's ricin toxin vaccine, RiVax(TM), has been shown to be well tolerated and immunogenic in a Phase 1 clinical trial in normal vol...

DOR BioPharma Announces Publication of orBec(R) Clinical Pulmonary Data in Bone Marrow Transplantation

.... DOR's biodefense products in development are recombinant subunit vaccines designed to protect against the lethal effects of exposure to ricin toxin, botulinum toxin and anthrax. DOR's ricin toxin vaccine, RiVax(TM), has been shown to be well tolerated and immunogenic in a Phase 1 clinical trial in normal vol...

DOR BioPharma Reports 1st Quarter 2009 Financial Results and Reviews Recent Accomplishments

.... DOR's biodefense products in development are recombinant subunit vaccines designed to protect against the lethal effects of exposure to ricin toxin, botulinum toxin and anthrax. DOR's ricin toxin vaccine, RiVax(TM), has been shown to be well tolerated and immunogenic in a Phase 1 clinical trial in normal vol...

DOR BioPharma Reports Year-End 2008 Financial Results and Reviews Recent Accomplishments

.... DOR's biodefense products in development are recombinant subunit vaccines designed to protect against the lethal effects of exposure to ricin toxin, botulinum toxin and anthrax. DOR's ricin toxin vaccine, RiVax(TM), has been shown to be well tolerated and immunogenic in a Phase 1 clinical trial in normal vol...

DOR BioPharma Appoints Gregg Lapointe, CPA, MBA, to its Board of Directors

.... DOR's biodefense products in development are recombinant subunit vaccines designed to protect against the lethal effects of exposure to ricin toxin, botulinum toxin and anthrax. DOR's ricin toxin vaccine, RiVaxTM, has been shown to be well tolerated and immunogenic in a Phase 1 clinical trial in normal volun...

botulinum in Biological Products

Chicken Anti-Ras-related C3 botulinum toxin substrate 1 Polyclonal Antibody, Unconjugated from GenWay Biotech, Inc.

Description: Ras-related C3 botulinum toxin substrate 1...
Company:GenWay Biotech, Inc.

Rabbit Anti-RAC2 Polyclonal Antibody, Unconjugated from Proteintech Group, Inc.

Description:... ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)...
Company:Proteintech Group, Inc.

botulinum in Biological Dictionary

Masseter

...sseter is innervated by the masseteric nerve from the mandibular division ... Al-Muharraqi MA, Fedorowicz Z, Al Bareeq J, Al Bareeq R, Nasser M. botulinum toxin for masseter hypertrophy. Cochrane Database of Systematic Reviews 2009, Issue 1. ... Information about masseter in the free online Englis...

G2 phase

...A NEW, G2 - PHASE FORM OF CELL DEATH IN T-CELLS ... of programmed cell death that kills T-cells in the G2 phase of the cell cycle. ... C. botulinum C2 toxin delays the G2 /M phase transition in synchronized HeLa cells. ... not allow one to distinguish between cells in G2 phase and cell...