2008 AAAS Newcomb Cleveland Prize recognizes science paper on limb regeneration in newts

...rom which the new limb grows. The formation of the blastema requires signaling molecules from nearby nerves, t...in nAG helps to stimulate the proliferation of the blastema cells. The protein is secreted by both nervous-sys...d, which helps explain why nerves are required for blastema formation. Even when the nerve was severed beneath...

Regrowth of Zebrafish's Tail Fin may Offer Clues for Treating Human Injuries

...on and subsequent proliferation of the progenitor cells of the blastema.” A blastema is a little nub of cells that directs regeneration, much like the conductor...se, a tail fin. “It is most likely the inability of humans to form a blastema in the first place that renders us unable to re-grow arms and legs,” said C...

Blastema in Biological News

NIH EUREKA award funds research at WPI aimed at turning adult skin cells into stem-like cells

...he university. The goal of the first phase of the DARPA project was to induce the formation of blastema-like cells at an injury site in a mammal. A blastema is a ball of undifferentiated cells that in amphibians forms from cells that remain at the site of an amputation. It is capable of regrowing the missi...

Key to zebrafish heart regeneration uncovered

...n of the heart tissue is removed from zebrafish, a blastema forms at the site of injury. However, the progenit...ximately two weeks. The precursor cells within the blastema begin to differentiate into cardiac muscle cells a...chers found that biochemical signaling between the blastema and the epicardium is controlled in part by protei...

Newts which regrow their hearts

...emities is different. Unlike in the process with the heart, newts develop a blastema in this case. blastema cells have certain characteristics in common with stem cells, such as the d...

How does a zebrafish grow a new tail?

...on and subsequent proliferation of the progenitor cells of the blastema." A blastema is a little nub of cells that directs regeneration, much like the conductor...case, a tail fin. "It is most likely the inability of humans to form a blastema in the first place that renders us unable to re-grow arms and legs," said C...

New understanding of regeneration gained by Forsyth scientists

...astemas, undifferentiated cells from which an organ or body part develops, consistent with a role in long-range signaling relevant to specification of blastema positional identity. Dr. Levin and Taisaku Nogi closed down the gap junctions to determine the impact on regeneration. As a result, the planaria o...

Blastema in Biological Dictionary

Blastema

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