Bivalirudin

The future of interventional cardiology presented at TCT 2008

...ARNO: A Prospective Randomized Trial Comparison of bivalirudin and Unfractionated Heparin Plus Protamine in Patie...PLES: A Prospective Randomized Trial Comparison of bivalirudin and Unfractionated Heparin Plus Tirofiban in Patie...IRI: A Prospective Randomized Trial of an Extended bivalirudin Infusion in Patients Undergoing Percutaneous Coron...

TCT update: press conference schedule announced for TCT

...ARNO: A Prospective Randomized Trial Comparison of bivalirudin and Unfractionated Heparin Plus Protamine in Patie...PLES: A Prospective Randomized Trial Comparison of bivalirudin and Unfractionated Heparin Plus Tirofiban in Patie...IRI: A Prospective Randomized Trial of an Extended bivalirudin Infusion in Patients Undergoing Percutaneous Coron...

Angioplasty No Better Than Drug Treatment in Long Run

...ial testing a new clot-preventing drug, bivalirudin, against heparin, the standard treatment, in PCI. The study of 4,570 persons having PCI found that bivalirudin did not provide a net clinical benefit, said a group headed by physicians in Germany. More information Angioplasty is explained by the U.S. N...

NewYork-Presbyterian/Columbia physician-scientists present at ACC's 57th Annual Scientific Session

...pened artery. Safety and Effectiveness of bivalirudin in Patients With Acute Myocardial Infarction Under... Renal Function on the Safety and Effectiveness of bivalirudin in Patients With Acute Myocardial Infarction Under...of Advanced Age on the Safety and Effectiveness of bivalirudin in Patients With Acute Myocardial Infarction Under...

Different anticoagulant regimens yield equal results

...s), the thrombin (blood-clotting enzyme) inhibitor bivalirudin by itself (4,612 patients), or bivalirudin plus GB IIb/IIIa inhibitors (4,604 patients). A...an early invasive management strategy who received bivalirudin alone experienced similar rates of ischemic compli...

Newer Anticlotting Drug Safe, Effective for Heart Surgeries

... bivalirudin lowers bleeding risk for patients undergoing bypas...ns and similar procedures each year, Lincoff said. bivalirudin not only reduces the incidence of excess bleeding ...lved in clotting. The new agent used in the trial, bivalirudin (brand named Angiomax), acts directly on molecules...

HORIZONS AMI trial data will help set guidelines

...tion (CRF), show that the use of the anticoagulant bivalirudin following angioplasty in heart attack patients red...NS AMI trial, we sought to determine whether using bivalirudin instead of heparin and glycoprotein IIb/IIIa inhib... heparin plus a glycoprotein IIb/IIIa inhibitor or bivalirudin alone. The patients are to be followed for five ye...

Horizons AMI trial data to be presented at TCT 2007

..., Dr. Stone said. However, using the anticoagulant bivalirudin with angioplasty in patients with stable coronary ...I trial, we have sought to determine whether using bivalirudin in patients with a heart attack, who undergo angio...e same benefit. This study should determine if bivalirudin use is as efficacious as the standard anticoagula...

Cardiac Emergency Therapy Finds Single Medication Effective Vs. Combination Drugs

...rchers showed that an// anti-clotting agent called bivalirudin (brand name Angiomax?), when used by itself to tre...f major bleeding in patients who were treated with bivalirudin than there were with patients treated with heparin...or fewer blood transfusions. Patients who received bivalirudin alone had similar rates of ischemic complications,...

Bivalirudin, a new anti-clotting drug may be a safer option for treatment of acute coronary conditions

... A novel anti-clotting drug named bivalirudin is turning out to be a better option than combinat...reatment including heparin, or a package including bivalirudin or just bivalirudin.It was found that Bivalrudin r...nter in Ocala, commented, "This report states that bivalirudin can be used for patents with acute coronary syndro...

Bivalirudin in Medical Technology

ISAR-REACT 3 Pits Bivalirudin vs. Unfractionated Heparin in PCI

Will direct thrombin inhibitor excel with high-dose clopidogrel on board? CHICAGO, March 29 /PRNewswire/ -- A large randomized trial will shed light on the ideal combination of medications for preventing unwanted blood clotting during and shortly after percutaneous coronary intervention (PCI). ...

Addition of INTEGRILIN(R) (Eptifibatide) to Bivalirudin Plus Standard of Care Inhibits Platelet Aggregation in Patients Undergoing Elective Coronary Stenting

ORLANDO, Fla., Nov. 5 /PRNewswire-FirstCall/ -- Schering-Plough Corporation (NYSE: SGP ) and The Sinai Center for Thrombosis Research at Sinai Hospital of Baltimore today announced results of the recently completed CLEAR PLATELETS 2 (Clopidogrel Loading with Eptifibatide to Arrest the Reactiv...

Schering-Plough Announces Results of the Early ACS Trial

...protocol mandated either weight-based unfractionated heparin or weight- and renal-adjusted enoxaparin by investigator choice. After a study amendment, bivalirudin and fondaparinux were allowed as concomitant baseline antithrombotic therapies. If early clopidogrel was used, the recommended loading dose was 300 mg...

CHMP Recommends Expanded Use of Angiox(R) (Bivalirudin) in Europe for Patients With Acute Coronary Syndromes

...pe, is establishing supply chain capabilities for the territory, and has set up a central office in Zurich, Switzerland. The Medicines Company markets bivalirudin as Angiomax(R) in the United States. The European Society of Cardiology (ESC) in June 2007 published guidelines for the treatment of ACS that recomme...

Bivalirudin in Biological News

Findings released from 1 of the largest percutaneous coronary intervention trials ever

...ho were administered the direct thrombin inhibitor bivalirudin during primary angioplasty had a reduced rate of a...inhibitors (GPI). In the landmark global trial, bivalirudin was compared to heparin plus GPI in more than 3,60...gioplasty were randomly assigned to receive either bivalirudin with provisional use of GPI or heparin plus GPI. T...