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Topical treatment shown to inhibit HIV and herpes simplex virus infection

Mount Sinai School of Medicine researchers demonstrated that a gel applied in the vagina provides protection from both the human immunodeficiency virus (HIV) and the herpes simplex Virus. The study, presented at the 12th Conference on Retroviruses and Opportunistic Infections, is the first to show that a gel can retain anti-viral activity within the human vagina. The study, which was fund...

Novel antiviral technology inhibits RSV infection in mice

A novel antiviral treatment combiningnanoparticle and gene silencing technologies thwarts attacks ofrespiratory syncytial virus (RSV) -- a virus associated with severebronchitis and asthma, an animal study by University of South Floridaresearchers found. The study was reported in the January 2005 issue ofthe journal Nature Medicine.RSV infects lung cells and can be life-threatening in very...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

A widely-used class of drugs that keep the HIV-virus infection from progressing to AIDS may cause serious and potentially lethal heart rhythm disturbances in some patients. The finding of a Mayo Clinic-led investigation appears in the current edition of The Lancet. In collaboration with colleagues from the HIV Program of Hennepin County Medical Center, Minneapolis; the University of Minn...

Breast Cancer May Be 'Uniquely Sensitive' To Inhibitors Of PI3K Pathway

"Because up to 75 percent of breast cancerpatients have an abnormality in a specific cell signaling pathway,drugs that target different molecules along that pathway may beespecially effective for treating the disease, says a researcher fromThe University of Texas M. D. Anderson Cancer Center." A clearer picture is now emergingabout the importance of the phosphatidylinositol 3 kinase...

Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma

A novel delivery system that transports gene silencing nanoparticles into tumor cells has been shown to inhibit Ewing's sarcoma in an animal model of the disease. In this classic "Trojan horse" approach, a protein called transferrin that normally delivers iron into cells is modified to also smuggle into tumor cells siRNA (short interfering RNA) encased in nano-sized sugar polymers. The si...

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bit at Biology Products

Rabbit Anti-Aph-1aL, S Loop (92-115) Polyclonal Antibody, Unconjugated from Covance Research Products, Inc

Description:Polyclonal Antibody against Aph-1a (Aph-1aL,S Loop 92-115), O2F1 The gamma secretase is a multiprotein complex consisting of presenilin, nicastrin, Aph-1 and Pen-2; all four proteins are necessary for full proteolytic activity. The gamma secretase complex catalyzes cleavage of a number of integral membrane proteins including Amyloid precursor protein, Notch, Erb4 an...
Company:Covance Research Products, Inc

Rabbit Anti-Human Vitamin K-dependent Protein S (PROS1) Polyclonal Antibody, Unconjugated from Lifespan Biosciences

Description:Anti-PROS1 Polyclonal Antibody not assigne...
Company:Lifespan Biosciences

Mouse Anti-C1-inhibitor (C1-INH) Monoclonal Antibody, Unconjugated, Clone 8F3 from AntibodyShop A/S

Description:C1-inhibitor (C1-INH)...
Company:AntibodyShop A/S

Rabbit Anti-Human Sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 7 (SIRT7) Polyclonal Antibody, Unconjugated from Lifespan Biosciences

Description:Sirtuin 7 (SIRT7) Rabbit anti-Human Polyclonal Antibody Long term: -20C; Short term: +4C...
Company:Lifespan Biosciences

Rabbit Anti-Esa1 Polyclonal Antibody, Unconjugated from Abcam

Description:Rabbit polyclonal to Esa1 ( for all tested applications)....
Company:Abcam

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bit at Biology Technology

Decontamination and inhibition of ribonucleases

It is common knowledge in most laboratories that RNA is more susceptible to degradation than DNA. Unlike Deoxyribonucleases (DNases), which require metal ions for activity (and can therefore easily be inactivated with chelating agents such as EDTA), ribonucleases (RNases) have virtually no cofactor requirements and adv...

Measurement of proteasome inhibition in live cells in Molecular Devices microplate fluorometers

Proteins inside eukaryotic cells exist in a dynamic state, in a highly-regulated balance between synthesis and degradation. Whereas prot...

A Microtiter-based Assay for the Determination of ID50s of b-lactamase Inhibitors Employing Reporter Substrates Detected at UV or Visible Wavelengths (MaxLine Application Note #20)

β -lactamases are either plasmid or chromosomally encoded bacterial enzymes which hydrolyze β -lactam antibiotics. The majority of β -lactamases produced by clinical isolates are serine active site enzymes. One successful approach to combating the serine active site β -lactamases is the use of β -lactamase inhibit...

Protector RNase Inhibitor

from rat lung, recombinant Catalog Number Pack Size 3335399 2000 units 3335402 10000 units (5 vials of 2000 U...

Protector RNase Inhibitor Enhance the Protection of RNA against Degradation

Is a new type of RNase inhibitor and inhibits a wide known spectrum ofRNases. Does not interfere with the performance of enzymes in an assay - evenwhen high amounts (e.g., up to 16-fold the standard concentr...

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bit at Biology Definition

Selective serotonin reuptake inhibitor

(5-hydroxytryptamine or 5-HT), in the <a href="/ ?q=/ Biology-De...

Habitat

has a number of unrelated meanings: . . </ l...

Competitive inhibitor

: competitive and noncompetitive inhibition. , the molecule acts on the same active site as the normal enzyme <a href...

Barbiturate

. Some also are used as <a h...

bit at Biology Dictionary

Habituation

A simple kind of learning involving a loss...

Habitat

(from the Latin for "it inhabits") is the place where a particular <a hre...

Feedback inhibition

, 2nd Edition. Ne...

Competitive inhibition

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Barbiturate

A group of drugs derived from barbit s may be habit forming.<...

bit at Medicine News

Sweet Candies replace bitter Pills for Anaemia

Anaemia due to iron deficiency is one of the major cause of morbidity in most of the underdeveloped countries. Children with iron deficiency anemia may be reluctant to take extra vitamins or iron pills, as they are inadvertently inedible. But now Iron-fortified candies were effective for improving the iron status of young children and might be an affordable way to combat iron deficiency...

Doctor samples come under the ambit of advertisement

The supreme court of India has declared that distribution of physician's sample by pharmaceutical companies to the medical profession is in nature of advertisement expenditure falling within restrictive provisions of sub section (3A) of section 37 of Income Tax Act. The nature of the advertisement or publicity depends upon the nature and quality of the article in question. The p...

Food Habits Could Change Your Genes

Eating specific food could change your genes, say researchers after success in a rodent study.Researchers Moshe Szyf, Michael Meaney and colleagues at McGill University in Montreal have found that nutrients // and supplements changed genetics by switching on or off certain genes in rodents, reports science portal EurekAlert. The new research was conducted in the lines of a two-year-o...

Kids More Prone To Mosquito Bites

Children are more vulnerable to bites of mosquitoes that carry the malaria parasites, according to a study. Each year, malaria kills about two million people around the world, most of them children under five. //The disease kills more than one million children - 2,800 per day - each year in Africa alone, according to World Health Organisation (WHO). Researchers led by David Smith,...

Pharmacies in for a dose of bitter medicine

In a long-delayed move, the Foods and Drugs Department is beginning to bare its fangs at chemists and druggists operating without qualified pharmacists, an offence under the Indian Drugs and Cosmetics Act, 1940. According to official sources, not only does this common practice jeopardise the health of the masses -- it allows untrained people to deal with high-risk drugs -- it also end...

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bit at Medicine Products

Orbital Plates

Description:Small right. Teflon orbital plates....
Company:Bausch & Lomb Storz

Sidebiting Antrum Punch Forceps

Description:Right side cutting....
Company:Bausch & Lomb Storz

Ocu-pore Porous Orbital Implants

Description:Ocu-pore Porous Orbital Implants are comprised only of synthetic, medical grade, hydroxyapatite and have a controlled microstructure designed to support soft tissue ingrowth. Ocu-pore is available in a range of convenient sizes. The material is manufactured using a proprietary synthetic process which allows us to produce a highly porous, fully interconnected, biocompatible ceramic matrix similar...
Company:Ceramisys

1.5mm Orbital Floor Plates

Description:The Lorenz Orbital Floor Plates feature a unique design for easy contouring and anatomical fit. Plates are a CP titanium and .3mm thick for ease of use and malleability. 0.3mm profile for optimal malleability. Universal (left/right) anatomical shape for ease of use. Optical nerve cut out and smooth construction for optimal safety. Four sizes for optimal anatomical fit as shown....
Company:Lorenz Surgical (A Biomet Company)

MEDPOR Orbital Rim Implant (IMORI)

Description:The new Inferior Medial Orbital Rim Implant (IMORI) provides surgeons with an excellent alternative for patients with a deficient or recessed "tear trough" area often characterized as a look of fatigue or circles under the eyes....
Company:Porex Surgical Products Group

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bit at Medicine Technology

Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer

NEW YORK, July 12, 2007 /PRNewswire-FirstCall/ -- ImCloneSystems Incorporated and Bristol-Myers Squibb Company todayannounced results from an open-label Phase III study of ERBITUX(R)(Cetuximab) plus a taxane and carboplatin in the first-linetreatment for metastatic non-small cell lung cancer (NSCLC). Thestudy did not meet its primary endpoint of progression-freesurvival (PFS) as assessed...

Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis

SAN FRANCISCO, July 10, 2007 /PRNewswire/ -- PortolaPharmaceuticals, Inc. announced positive Phase II data on its leadcompound, PRT054021, an oral Factor Xa inhibitor, today at the XXICongress of the International Society on Thrombosis and Haemostasis(ISTH) in Geneva, Switzerland. The EXPERT trial showed thatPRT054021 was safe, effective, and well tolerated for theprevention of venous th...

Peer Reviewed Journal Article Indicates Repros' Proellex Exhibits Potential for New Approach to the Treatment and Prevention of Breast Cancer

THE WOODLANDS, Texas--(BUSINESS WIRE)--Jul 5, 2007 - ReprosTherapeutics Inc. (NasdaqGM:RPRX) today announced that an articlehas been published in the July 1, 2007 issue of Oncology Reportsindicating a potential for a new approach to the treatment ofbreast cancer using Proellex. The article reviews the findings froma study conducted in an accepted in vivo rat model of breastcancer. The study...

Major New Review Supports the Broader Potential of CeNeS COMT Inhibitor Discovery Programme

CAMBRIDGE, U.K. 2nd July 2007 - CeNeS Pharmaceuticals (AIM:CEN)("CeNeS" or "the Company") the Cambridge-based biopharmaceuticalcompany today announced that a paper published this week in CNSDrugs(1) further supports the hypothesis that acatechol-O-methyltransferase (COMT) inhibitor that acts in thebrain would be a useful agent to address profound cognitivedeficits in schizophrenia and bi...

Arisaph Pharmaceuticals Announces Results of its Potent Smart DPP-4 Inhibitor, ARI-2243, at the ADA

- ARI-2243 is an highly potent DPP-4 inhibitor, possessing Ki of 27pM BOSTON, June 25, 2007 /PRNewswire/ -- Arisaph Pharmaceuticals,Inc., a privately held drug discovery biopharmaceutical company,announced today the results of its potent, smart DPP-4 inhibitor,ARI-2243, presented at the 67th session of the American DiabetesAssociation meeting in Chicago, Illinois. The results showed that...

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bit at Medicine Definition

Depolarization-induced suppression of inhibition

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bit at Medicine Dictionary

Tick bites

or Rocky Mountain spotted <a href="/ ?q=/ Medicine-Dictionary...

Thrombophlebitis

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Stork bite

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Snakebite

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Snake bite

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