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Biomarkers at Biology News

Biomarkers isolated from saliva successfully predict oral and breast cancer

Screening for breast cancer and the early detection of other tumors one day may be as simple as spitting into a collection tube or cup, according to recent studies by UCLA researchers. In one early study based on a risk model, presented here at the 96th Annual Meeting of the American Association for Cancer Research, the UCLA scientists reported that genetic "biomarkers" isolated in saliva...

Measurement Challenges In Detecting Cancer Biomarkers

Effective control of sexually transmitted diseases (STDs) requires treatment of the sexual partners of infected patients. A new study shows that providing infected men with antibiotics to give their partners is more effective than traditional means of contacting and treating the partners, according to an article in the Sept. 1 issue of Clinical Infectious Diseases, now available online. Men with...

Biomarkers may hone anti-aging therapies

Lotions and potions that promise to remove wrinkles and other effects of aging crowd cosmetics aisle shelves, but do these treatments really work? Vanderbilt University Medical Center investigators have identified new molecular indicators -- or "biomarkers" -- of aging in the skin that could be used to evaluate anti-aging therapies. Their findings are reported in the February issue of the...

Scientists create dual-modality microbeads to improve identification of disease biomarkers

Analyzing human blood for a very low virus concentration or a sample of water for a bioterrorism agent has always been a time-consuming and difficult process. Researchers at the Georgia Institute of Technology and Emory University have developed an easier and faster method to detect these types of target molecules in liquid samples using highly porous, micron-sized, silica beads. The res...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

Genetic and epigenetic variations ensure that no two people are exactly alike, and the same holds true for any two cancers. Now, researchers have the tools and the knowledge to help predict how individuals will respond to cancer therapies, enabling them to create more effective therapies for individual cancers ?personalized medicine. At the 2007 Annual Meeting of the American Association for Can...

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MicroRNA Profiling by Array Analysis Reveals Critical BioMarkers

Jaclyn Shingara, Kerri Keiger, Ila Wolf, Jeffrey Shelton, Emmanuel Labourier, and David Brown R&D Division, Ambion, Inc. MicroRNAs (miRNAs) are small, siRNA-like molecules, encoded in the genomes of plants and animals,...

Multiplexed Quantitative Peptide Assays for Protein Biomarkers of Cardiovascular Disease in Human Plasma

As the study of protein biomarkers increases in importance, extensive lists of candidate markers are being developed based on protein pathway information and discovery-based proteomics experiments. Even larger numbers of candidate genomic markers exist from DNA transcriptional profiling based on microarray-based gene expressio...
Biomarkers at Medicine News

Biomarkers May Indicate Alzheimer's Disease

The early signs of Alzheimer's disease can be identified by using the compounds, or biomarkers in the cerebrospinal fluid, according to scientific research conducted by Sweden’s Lund University.// Loss of memory and confusion can also be interpreted as early signs of the onset of the disease, and it is not always easy to differentiate the symptoms of Alzheimer's, and that of growing old....

Biomarkers Could Prove Significant In Understanding Aging Process

Researchers at the Vanderbilt University Medical Center have zoned in on new molecular indicators, called "biomarkers", // for aging of the skin that could be an interesting pointer when evaluating anti-aging therapies. The findings of this particular study are reported in the latest issue of the Journal of Investigative Dermatology. “There's a lot of interest in the pharmaceutical and...

Researchers Find Mix of Biomarkers Predicting Mortality

Previous research has uncovered a range of biological markers that can predict disability, morbidity and mortality in older adults. In this study, the researchers// analyzed 13 biomarkers representing neuroendocrine and vascular functions and immune and metabolic activity over 12 years in 1,189 high-functioning men and women aged 70-79 enrolled in the MacArthur Study of Successful Aging. The goal...

Biomarkers Predicting Mortality Found Using Statistical Technique

A recent study was conducted to identify biomarker combinations associated with mortality among people.Previous research //has uncovered a range of biological markers that can predict disability, morbidity and mortality in older adults. In this study, the researchers analyzed 13 biomarkers representing neuroendocrine and vascular functions and immune and metabolic activity over 12 yea...

Biomarkers Found Harmful For Human Lupus

A team of Wake Forest University School of Medicine has found biomarkers for lupus that may play a role in causing the disease. //The biomarkers are micro-ribonucleic acids (micro-RNAs), said Nilamadhab Mishra, M.D. Mr. Mishra and his colleagues reported at the American College of Rheumatology meeting in Washington that they had found profound differences in the expression of micro-RNAs...

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Pharmacyclics Identifies Functional Biomarkers for its Novel HDAC Inhibitor and Demonstrates Preclinical Anti-Tumor Activity with Bruton's Tyrosine Kinase Inhibitors

SUNNYVALE, Calif. and LOS ANGELES, April 18, 2007/PRNewswire-FirstCall/ -- Pharmacyclics, Inc. today announced datafrom two preclinical studies, one identifying a functionalbiomarker for its novel histone deacetylase (HDAC) inhibitor andanother demonstrating preclinical anti-tumor activity with itsBruton's tyrosine kinase (BTK) inhibitor compounds. The data werepresented at the American...

Millennium Discovers Biomarkers Potentially Predictive of Response to Velcade (Bortezomib) for Injection

- Findings Published in Blood Highlight Millennium Leadership inPersonalized Medicine and Could Strengthen the Role of VELCADE asFoundation of Therapy in Broad Range of Multiple Myeloma Patients - CAMBRIDGE, Mass., April 17, 2007 /PRNewswire-FirstCall/ --Findings published in the April 15th issue of Blood show that ateam of researchers led by Millennium Pharmaceuticals, Inc. hasdiscovered...
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(Date:10/7/2008)...alth-related Questions for Tonight,s,Presidential ...- WebMD, the leading source of,health information,...ial,candidates, proposed health care policies, loc...t the candidates, stance on health insurance, medi... public health issues., The in-depth coverage is ...
(Date:10/7/2008)...PRNewswire-USNewswire/ -- The Ohio Nurses,Associat...ced today its,final round of endorsed candidates f...o Senate:, SD 26 Karen Gillmor (R) Tiffin, Ohio ...(R) Grove City;, HD 28 Connie Pillich (D) Cincinn...These ONA-endorsed candidates for the Ohio General...
(Date:10/7/2008)...wswire-USNewswire/ -- Kristi Yamaguchi, Olympic,Go... the Stars, has been,named chairperson for the 200...gn in an effort to help raise funds in support of ...e and promote lung health., The American Lung Ass...o conquer Tuberculosis. Today, the Lung Associatio...
(Date:10/7/2008)...ar to more expensive whole-leg color ultrasound, ...lthDay News) -- An older, simpler test to look for...osis, or DVT -- is as effective as a newer, more e...searchers found that 2-point ultrasonography of th...trasound -- was as good at detecting DVT as the ne...
Breaking Medicine News(10 mins):Health News:WebMD Highlights Presidential Candidates' Views on Health Care 2Health News:ONA-PCE Announces Final Round of Endorsed Candidates for Ohio General Assembly 2Health News:ONA-PCE Announces Final Round of Endorsed Candidates for Ohio General Assembly 3Health News:Kristi Yamaguchi Chairs American Lung Association Christmas Seals Campaign 2Health News:Simpler Test May Be Best for Diagnosing Blood Clots in Leg 2Health News:Simpler Test May Be Best for Diagnosing Blood Clots in Leg 3
(Date:10/6/2008)...ch study funded by JDRF suggests that a common int...developing type 1 diabetes. The findings provide a... type 1 diabetes develops in people, and may lead ...week in Nature Magazine, lends further support t...propriate amount and composition of bacteria may b...
(Date:10/6/2008)... awarded the 2008 SNM Wagner-Torizuka Fellowship a...ough 2010 as part of the two-year program., These...al College, undertaking a fellowship at Johns Hopk... Hospital, studying at the University of Washingto...g at Cedars Sinai Medical Center, Los Angeles; and...
(Date:10/6/2008)...ent kinds of cells have in common with a mixture o...mixtures to separate into two distinct regions. ,...l computer model of the cell sorting process produ...s at Vanderbilt University, and his colleagues at ...ibed in the Oct. 3 issue of the journal Physical ...
(Date:10/6/2008)...ty are using nanotechnology to search for new canc...up to 10,000 times faster than current methods. ,...f chemicals simultaneously using tiny plastic bead...uman hair. Each bead carries a separate chemical,...properties needed to treat cancer cells. One batc...
Breaking Biology News(10 mins):JDRF funded study links 'hygiene hypothesis' to diabetes prevention 22008 SNM Wagner-Torizuka Fellowships announced 22008 SNM Wagner-Torizuka Fellowships announced 3Surface tension drives segregation within cell mixtures 2Nanoscopic screening process to speed drug discovery 2MonoSol Rx Completes Thin Film Ondansetron Pilot Bioequivalence Study 1402 1MonoSol Rx Completes Thin Film Ondansetron Pilot Bioequivalence Study 1402 2MonoSol Rx Completes Thin Film Ondansetron Pilot Bioequivalence Study 1402 3Purging the plantain pests in Africa 2284 1Purging the plantain pests in Africa 2284 2Guidelines for evaluation of psychological side effects of brain injury 12405 1Guidelines for evaluation of psychological side effects of brain injury 12405 2Guidelines for evaluation of psychological side effects of brain injury 12405 3Comparison of venlafaxine and SSRIs in the treatment of depression 12403 1Comparison of venlafaxine and SSRIs in the treatment of depression 12403 2
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