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Biomarker in Medical News

SNM's Clinical Trials Network expands European membership of PET biomarker manufacturers

Reston, Va.SNM's Clinical Trials Network today announced that several leading commercial providers of PET radiopharmaceuticals in Europe have registered their manufacturing sites with the network. SNM's Clinical Trials Network is an initiative designed to address the need for streamlined drug disc...

New Diagnostic Biomarker Test Shows Promise in Monitoring Ovarian Cancer

CHICAGO, July 22 /PRNewswire-FirstCall/ -- Ovarian malignancies are a leading cause of cancer death in women because they are usually detected in the late stages when the disease is incurable. Encouraging new research presented by Abbott today at the American Association for Clinical Ch...

JNCI news brief: Improving the biomarker pipeline for early cancer detection

Several statistical and biological issues need to be addressed in order to improve biomarker identification for early detection of cancer, according to a commentary published online July 2 in the Journal of the National Cancer Institute . The biomarker pipeline to develop and evaluate cancer s...

Study identifies biomarker that safely monitors tumor response to new brain cancer treatment

LOS ANGELES (STRICTLY EMBARGOED UNTIL 12:01 A.M. EDT on JULY 1, 2009) A specific biomarker, a protein released by dying tumor cells, has been identified as an effective tool in an animal model to gauge the response to a novel gene therapy treatment for glioblastoma mulitforme. The finding, repor...

New Prostate Cancer Biomarker Discovered

Finding also might apply in other types of cancer, researcher says THURSDAY, June 18 (HealthDay News) -- A new marker for advanced prostate cancer and metastasis, or spread, of the disease has been identified by U.S. researchers. Their analysis of prostate tissue from men with local...

Promising biomarker and candidate tumor suppressor gene identified for colorectal cancer

Researchers have identified a new candidate tumor suppressor gene in colorectal cancer and examined its use as a potential biomarker in stool samples, according to a new study published online June 17 in the Journal of the National Cancer Institute . In the study, Manon van Engeland, Ph.D., of...

VBI researchers develop new method for breast cancer biomarker discovery

Blacksburg, Va. -- Three researchers from the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed and evaluated a new one-step bioanalytical approach that allows them to profile in detail complex cellular extracts of proteins. The method has allowed the scientists to look at ho...

Michael J. Fox Foundation Announces $2 Million Funding Commitment to Drive Development of Parkinson's Disease Biomarker Pipeline

Initiative is one element of broader strategy to speed biomarkers progress NEW YORK, May 7 /PRNewswire-USNewswire/ -- The Michael J. Fox Foundation for Parkinson's Research announced a funding commitment of $2 million for Biomarkers 2009 . This fourth round of biomarker funding by MJFF ai...

New biomarker may predict leukemia aggressiveness

Scientists at the University of California, San Diego and the Moores UCSD Cancer Center have evidence of a potential new biomarker to predict the aggressiveness of an often difficult-to-treat form of leukemia. They found that high levels of a particular enzyme in the blood are an indicator that ch...

Wayne State University Scientists ID New Biomarker for Prostate Cancer

DETROIT, March 26 /PRNewswire-USNewswire/ -- Researchers at Wayne State University have identified a new marker for prostate cancer progression that may one day lead to new treatments. Prostate cancer, one of the most prevalent non-skin cancers in America, affects one in six men. In 20...

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Biomarker in Medical Technology

Clinical Genomics Continues Progress in Developing Biomarker Portfolio for Colorectal Cancer Testing

SYDNEY, April 29 /PRNewswire/ -- Clinical Genomics Pty Ltd, an Australian biotechnology company, announced today that Quest Diagnostics Incorporated, the world's leading provider of diagnostic testing, information and services, has agreed to provide milestone payments over the next two years t...

Adlyfe Strikes Translational Medicine Partnership With Wyeth Pharmaceuticals for Alzheimer's Biomarker Assay

ROCKVILLE, Md., Feb. 25 /PRNewswire-USNewswire/ -- Adlyfe, a private company developing novel biomarkers and diagnostic tests for amyloid diseases, announced today that it has signed an agreement with Wyeth Pharmaceuticals, a division of Wyeth, to develop biomarker assays designed to measure level...

Transgenomic and Power3 Medical Complete Agreement for Exclusive License of Neurodegenerative Biomarker Test

Targets Diagnosis and Early Detection of Alzheimer's and Parkinson's Diseases OMAHA, Neb. and HOUSTON, Feb. 2 /PRNewswire-FirstCall/ -- Transgenomic, Inc. (OTC Bulletin Board: TBIO) and Power3 Medical Products, Inc. (OTC Bulletin Board: PWRM) today announced they have finalized a transaction,...

Pivotal Data Published For First Biomarker Combination Test to Determine Risk of Ovarian Cancer in Women Who Present With Pelvic Mass

Article in Gynecologic Oncology Supports Use of Fujirebio Diagnostics' HE4 Test with CA125 for Risk Stratification of Women with Suspected Ovarian Cancer MALVERN, Pa., Jan. 26 /PRNewswire/ -- A pivotal clinical trial published in the January 2009 issue of the journal Gynecologic Oncology ...

WaferGen and University of Texas Southwestern Medical Center Establish Biomarker Research Collaboration for SmartChip(TM) Real-Time PCR System

UT Southwestern to Identify and Validate Novel Gene Expression Biomarkers Involved in Wound Healing with Innovative Gene Expression Platform FREMONT, Calif., Jan. 8 /PRNewswire-FirstCall/ -- WaferGen Biosystems, Inc. (OTC Bulletin Board: WGBS), a leading developer of state-of-the-art gene exp...

Nemours Center for Childhood Cancer Research Team at the Alfred I. duPont Hospital for Children Identifies the Function of a Biomarker Present in Prostate Cancer Cells: New Insight into Therapeutic Benefit for Patients with Advanced Prostate Cancer

WILMINGTON, Del., July 17 /PRNewswire/ -- The research team at the Nemours Center for Childhood Cancer Research (NCCCR), a newly established division of Nemours Biomedical Research at the Alfred I. duPont Hospital for Children has discovered that the biomarker called prostate specific membrane...

Pressure BioSciences, Inc. Announces $850,000 NIH SBIR Phase II Award for the Development of a New PCT-dependent System for Improved Biomarker Discovery, Diagnostics, and Drug Discovery

SOUTH EASTON, Mass., June 24 /PRNewswire-FirstCall/ -- Pressure BioSciences, Inc. (Nasdaq: PBIO ) ("PBI" and "the Company") today announced that it has been awarded a Phase II Small Business Innovation Research (SBIR) Grant (2R44GM079059-02) from the National Institutes of Health (NIH). The G...

EnVivo Pharmaceuticals Announces Initiation of Clinical Safety and Biomarker Study of Alpha-7 Nicotinic Agonist, EVP-6124, in Patients with Schizophrenia

BOSTON, April 2, 2008 /PRNewswire/ -- EnVivo Pharmaceuticals announced today that it has initiated a clinical safety and biomarker study of its alpha-7 nicotinic agonist (EVP-6124) in Schizophrenia patients chronically treated with atypical antipsychotic medications. The objectives of this stu...

BiPar Begins Phase 2 Study of Lead PARP Inhibitor in Triple-Negative Breast Cancer Based on Overexpression Biomarker Data

BRUSSELS, Belgium and BRISBANE, Calif., Nov. 15 /PRNewswire/ -- BiPar Sciences, Inc., a privately held biopharmaceutical company developing novel cancer therapies, today announced it has initiated a Phase 2 study of its lead PARP inhibitor, BSI-201, in patients with triple-negative breast canc...

BiPar Genomic Biomarker Data Demonstrate Overexpression of PARP-1 Gene in Multiple Cancer Types

SAN FRANCISCO, Oct. 25 /PRNewswire/ -- BiPar Sciences, Inc., a privately held biopharmaceutical company developing novel cancer therapies, today announced molecular biomarker data demonstrating the overexpression of the PARP (poly-ADP-ribose polymerase) protein in multiple cancers, including o...
Biomarker in Medical Definition

Personalized medicine

...epending on many factors, including environmental circumstances. The outcome is the development of biomarkers which are stable and predictive. Today's biomarker is tomorrow's theranostic. The infrastructure necessary includes molecular information -biological specimens derived from tissue, cells, or blood pr...
Biomarker in Medical Dictionary

Progressive Supranuclear Palsy

... section of our Links ... Progressive supranuclear palsy (PSP) is a degenerative neurological disorder of ... Tau forms in CSF as a reliable biomarker for progressive supranuclear palsy . ... Progressive supranuclear palsy (PSP) is a rapidly progressing degenerative ... Progressive ...
Biomarker in Biological News

New biomarker method could increase the number of diagnostic tests for cancer

A team of researchers, including several from UCSF, has demonstrated that a new method for detecting and quantifying protein biomarkers in body fluids may ultimately make it possible to screen multiple biomarkers in hundreds of patient samples, thus ensuring that only the strongest biomarker candi...

CHIs 5th Biomarker World Congress: Signature Event with Cutting-Edge Agenda

Needham, MA, March 26, 2009 / b3c newswire / - Cambridge Healthtech Institute’s Fifth Annual Biomarker World Congress will be held May 27-29, 2009 at the Loews Philadelphia Hotel, Philadelphia, Pennsylvania. The advance registration deadline for this event is April 10, 2009. The signature e...

Vitamin C lowers levels of inflammation biomarker considered predictor of heart disease

Berkeley -- A new study led by researchers at the University of California, Berkeley, adds to the evidence that vitamin C supplements can lower concentrations of C-reactive protein (CRP), a central biomarker of inflammation that has been shown to be a powerful predictor of heart disease and diabet...

Singulex Teams With Wyeth Pharmaceuticals to Translate Pre-Clinical Biomarker Research Into Clinical Study Design

HAYWARD, Calif., Nov. 27 /PRNewswire/ -- Singulex Inc. today announced that it is collaborating with researchers at Wyeth Research to develop immunoassays on the company's Erenna(TM) system. Singulex has installed the Erenna system at Wyeth as part of its Erenna Technology Access Program (ETAP...

Researchers seeking to identify Alzheimer's risk focus on specific blood biomarker

NEW YORK A simple blood test to detect whether a person might develop Alzheimer's disease is within sight and could eventually help scientists in their quest toward reversing the disease's onset in those likely to develop the debilitating neurological condition. Building on a study that starte...

Newly identified biomarker detects and regulates spread of brain tumors

Researchers at Emory University's Winship Cancer Institute have identified a novel biomarker for brain tumors and have uncovered a potential role the marker may play when the tumor spreads or comes back after treatment. The study, Ã’Attractin is elevated in the cerebrospinal fluid of patients with ...

First biomarker for human sleepiness identified in fruit flies

Scientists have identified the first biochemical marker linked to sleep loss, an enzyme in saliva known as amylase, which increases in activity when sleep deprivation is prolonged. Researchers hope to make amylase the first of a panel of biomarkers that will aid diagnosis and treatment of sleep d...

Scientists open doors to diagnosis of emphysema

...performed in mice, the researchers hope that in future it will be possible to adapt the test for use in patients. "It would allow us to use MMP12 as a biomarker to monitor disease evolution and the risk of emphysema formation. It could also serve to examine the response to therapeutic interventions in patients...

$2 million grant aids study of lung cancer in people who never smoked

...h Center in Seattle, University of Southern California and at the British Columbia Cancer Agency in Vancouver will undertake a coordinated approach to biomarker discovery, using their expertise to study the same sets of specimens by different methods. Researchers hope to open the project to additional research...

Pitt team first to profile genes in acutely ill idiopathic pulmonary fibrosis patients

...he blood of patients experiencing an exacerbation. If the findings are verified with more research, which is underway, the proteins could be the first biomarker blood tests that doctors could track to identify patients at risk for sudden deterioration of lung function. "This work opens an important window ...

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Biomarker in Biological Technology

Investigational Urine NGAL Biomarker Shows Promise to Monitor Cyclosporine Toxicity in Cardiac Transplant Patients

CHICAGO, July 22 /PRNewswire-FirstCall/ -- Research presented at the American Association for Clinical Chemistry (AACC) annual meeting today indicates that monitoring cardiac transplant patients with the Urine NGAL assay on Abbott's ARCHITECT immunoassay analyzer may help clinicians to m...

Genedata Launches Expressionist with Expanded Mass Spectrometry Biomarker Discovery Capabilities

Genedata Expressionist 5.2 with enhanced capabilities for Mass Spectrometry-based biomarker discovery will be demonstrated at the 57th ASMS Conference on Mass Spectrometry, May 31 - June 4, 2009, Booth# 133 at the Pennsylvania Convention Center. Philadelphia, PA (PRWEB)...

Caprion Proteomics Inc. and Applied Bioystems Work Together to Accelerate Protein Biomarker Verification and Validation

Combination of industry-leading services with unique QTRAP(R) technology MONTREAL, May 28 /PRNewswire/ -- Caprion Proteomics Inc. today announced that it is working with Applied Biosystems, a division of Life Technologies Corporation (Nasdaq: LIFE ), to accelerate the verification and valid...

BD and Fujirebio Diagnostics Sign Worldwide Agreement to Develop Biomarker Assays to Improve Cancer Detection and Management

Alliance Aims to First Develop Powerful Tools for Detecting Ovarian Cancer Earlier FRANKLIN LAKES, N.J. and MALVERN, Pa., May 4 /PRNewswire-FirstCall/ -- BD (Becton, Dickinson and Company) (NYSE: BDX ) and Fujirebio Diagnostics, Inc., announced today the signing of a worldwide development ...

Clarient Granted Exclusive License to Commercialize Breast Cancer Biomarker by Indiana University Research and Technology Corporation

FOXA1 biomarker predicts likelihood of recurrence and long-term disease-free survival of breast cancer patients; Further strengthens Company's breast cancer menu ALISO VIEJO, Calif., April 23 /PRNewswire-FirstCall/ -- Clarient, Inc. , (Nasdaq: CLRT ), a premier anatomic pathology and mol...

HUYA Bioscience Announces Strategic Alliance With Abbott on Drug and Biomarker Development Candidates From China

Collaboration will leverage HUYA's growing Chinese bioscience network SAN DIEGO, April 21 /PRNewswire/ -- HUYA Bioscience International, a leader in US/China pharmaceutical co-development, today announced an agreement with Abbott to identify and pursue proprietary preclinical and clinical d...

Vermillion Announces Notice of Issuance of U.S. Patent Covering Hepcidin as a Biomarker for Ovarian Cancer

- Discovery Could Lead to the Development of a Next-Generation Assay to Improve Diagnosis and Treatment of Ovarian Cancer - FREMONT, Calif., Feb. 12 /PRNewswire-FirstCall/ -- Vermillion, Inc. (OTC Bulletin Board: VRML), a molecular diagnostics company, today announced that the U.S. Patent Off...

Rules-Based Medicine, Inc. Launches Human Kidney Damage Biomarker Panel

Complements the RBM Rat Kidney Panel developed in conjunction with the Critical Path Initiative AUSTIN, Texas, Jan. 15 /PRNewswire/ -- Rules-Based Medicine, Inc. (RBM), the world's leading multiplexed biomarker testing laboratory, today announced the launch of its Human Kidney Multi-Analyte P...

Oncology Biomarker KRAS to be Discussed at FDA Panel Meeting

KRAS Biomarker PresentsPotential toPersonalize Colorectal Cancer Treatment Determining Who Can Benefit from Vectibix(R) THOUSAND OAKS, Calif., Dec. 16 /PRNewswire-FirstCall/ --Amgen (Nasdaq: AMGN ) today announced they will discuss the clinical utility of the KRAS gene as a predictiv...

Genstruct Added to The Biomarker Consortium's Rapidly Growing Roster of Industry Experts

CAMBRIDGE, Mass., Nov. 4 /PRNewswire/ -- Genstruct Inc., a systems biology company focused on identifying molecular mechanisms, networks and biomarkers to better develop novel therapeutics and molecular diagnostics, today announced that it has become a member of The Biomarker Consortium, a pub...
Biomarker in Biological Products

Serum Biomarker Chip from Whatman, Inc

Description: The first high-density serum biomarker chip to profile the relative abundance of cancer serum proteins. An antibody chip containing 120 human cancer serum biomarker-specific antibodies. A research tool that enables biomarker discovery scientists to study panels of biomarkers related to early detect...
Company:Whatman, Inc

ProteinChip System, Series 4000 from Ciphergen

Description:...d by todays clinical researchers and biologists in biomarker research. The Series 4000 delivers improved performance, offering the fastest route for converting biomarker discoveries to biomarker assays all on the same platform. The Series 4000 i...
Company:Ciphergen

MIDAS TRAQ System with 4000 Q TRAP LC/MS/MS System from Applied Biosystems

Description:...e ability to go directly from genomic or proteomic biomarker prediction, profiling, and discovery experiments to assays for biomarker verification and validation. The workflow for biomarker verification overcomes the need for separate metho...
Company:Applied Biosystems

CiphergenExpress Software from Ciphergen

Description:... Successful biomarker discovery projects require screening through a huge volume of samples to di...o help better manage the complex sample tracking and data flood inherent to biomarker discovery. The CiphergenExpress Software package provides a robust, client-...
Company:Ciphergen

GeneSpring Workgroup from Agilent Technologies

Description:...kgroup can reduce the cost of bringing drugs to market by providing better predictive toxicology assessments and more thorough analysis techniques for biomarker discovery....
Company:Agilent Technologies

LTQ XL Linear Ion Trap from Thermo Scientific

Description:...tion Platform for high resolution, accurate mass hybrids Whether you analytical challenge is metabolic profiling, mining for metabolites or biomarker discovery, the LTQ XLs exceptional suite of innovative techniques and software makes it the instrument of choice. More fragments more spectral treesm...
Company:Thermo Scientific

Rainbow trout Vitellogenin EIA Kit from Cayman Chemical

Description:... Detection of the yolk protein Vtg in plasma from juvenile or male fish is a simple and sensitive biomarker for endocrine disrupting chemicals (EDCs) with estrogenic effects in fish. Quantification of Vtg has become an accepted screening test for the estroge...
Company:Cayman Chemical

Rainbow trout Vitellogenin EIA Kit from Cayman Chemical

Description:... Detection of the yolk protein Vtg in plasma from juvenile or male fish is a simple and sensitive biomarker for endocrine disrupting chemicals (EDCs) with estrogenic effects in fish. Quantification of Vtg has become an accepted screening test for the estroge...
Company:Cayman Chemical

LCMS-IT-TOF Formula Predictor System from Shimadzu

Description:... The first LCMS system to fully utilize the information-rich content of MSn data in formulae prediction, Shimadzus LCMS-IT-TOF addresses the needs of biomarker discovery, trace amount impurity identification, and natural products research....
Company:Shimadzu

Pathway Studio Enterprise from Ariadne Genomics

Description:...fy relationships among genes, cell processes, diseases and treatments Discover cellular responses to drug target candidates Facilitate biomarker discovery Predict side effects in toxicology studies Interpret gene expression and proteomics data Track research data across ...
Company:Ariadne Genomics
Biomarker in Biological Dictionary

Protein array

... The array is a piece of glass on which different molecules of protein or ... on the array 's surface the conjugated ... biomarker Discovery using Protein Arrays ... Cell-free protein array technology produces protein microarrays by performing in vitro synthesis of ...

Locus

.... In the fields of genetics and evolutionary computation, a locus (plural loci) is a fixed position on a chromosome such as the position of a biomarker that may be occupied by one or more genes. A variant of the DNA sequence at a given locus is called an allele. The... locus n. , pl. -ci ( )....

Loci

... In the fields of genetics and evolutionary computation, a locus (plural loci ) is a fixed position on a chromosome such as the position of a biomarker that may be occupied by one or more genes. A variant of the DNA sequence at a given locus is called an allele. The... The 'method of loci ...

Gene expression

...throughput gene expression data and hybridization arrays, chips, microarrays. TissueScan qPCR Arrays, Disease Panels for gene expression , biomarker validation and SNP analsysis across many stages of Disease progression from high quality, ... Gene Expression . NEW! SGC Expression Clones. cD...

Abiotic stress

...s Identified ... ... novel role of helicases and G-proteins in abiotic stress tolerance in plant) ... Abiotic Stress Tolerance agrogenomics biomarker discovery Biomarkers cancer ... Abiotic stress generates signals. Full Text - Oct 18, 2007 ... North Texas e-News,He calls it abiotic stre...
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