Syracuse University researchers build a new surface material that resists biofilm growth

This is the tale of two biological substancescells from mammals and bacteria. It's a story about the havoc these microscopic entities can wreak on all manner of surfaces, from mighty ships to teeth and medical devices, and how two Syracuse University researchers are discovering new ways prevent th...

Muskogee Community Hospital Adopts Steril-Aire UVC Lights for Infection Control, Green Benefits

...asy to access and service. Even with the ease of service, UVC offers an important advantage: It continuously cleans the coil and drain pan surfaces of biofilm buildup, reducing or eliminating the need for costly manual cleaning and keeping the units in 'as-new' condition so they run more efficiently," Martin...

Study aims to induce recovery from ankylosing spondylitis

...rane Collaboration in evidence-based medicine. The treatment protocol is based on a molecular understanding of the interaction of intracellular and biofilm bacteria with the operation and control of the body's nuclear receptors. Dysregulation of these receptors has been shown to promote the systemic infl...

Materials and Processes for Medical Devices Event Brings Clinicians, Engineers, Designers Together

...s, the relative roles of osteolysis and hypersensitivity by particulate debris to loosening of metal-on-metal hips, and a possible ossible approach to biofilm inhibition. Corrosion, Fatigue and Durability of Medical Devices will address current corrosion and durability issues facing implant designers and...

Thus the bile does not overflow

...ng the bacteria were gathered by statistical means. "We could show that the colonization of the stents followed principles ressembling those known for biofilm development of dental plaques" Pieper said. In the future, the scientists will analyze the influence of different environmental factors such as a...

New UVC Kit Destroys Microorganisms Including flu Viruses, Bacteria and Mold

...nants to greatly reduce the spread of infectious diseases and eliminate the major source of allergy and asthma discomfort. It also eliminates surface biofilm to keep coils and drain pans in a constantly clean state, saving money by reducing HVAC energy use and eliminating costly chemical cleanings. The...

Transave Completes Enrollment in Arikace(TM) Phase II Bronchiectasis Study

...es biocompatible lipids endogenous to the lung that are formulated into small (0.3 micron), neutrally-charged liposomes that enable penetration of the biofilm and are highly efficient, with a very low lipid-to-drug ratio (0.65). Arikace can be delivered through nebulization, which enables the small aer...

Anti-microbial catheter to cut infection risk for dialysis patients

...ries and spina bifida. This will involve some adaptation to cover specific pathogens such as, in the case of foley catheters, Proteus which produces a biofilm on the catheter and converts urea in urine into ammonia, causing minerals and phosphates to form a painful crystallised crust at the neck of the cathe...

IADR and GlaxoSmithKline Consumer Healthcare announce winners of 2009 Innovation in Oral Care Awards

...c Reynolds, B.Sc., Ph.D., The University of Melbourne School of Dental Science, Australia, for "Development of Oxantel to Prevent Periodontopathogenic biofilm Formation." Oxantel is already approved for use in humans at relatively high concentrations as a treatment for intestinal parasites. Reynolds and his ...

University of Texas engineers receive $3.2 million in National Science Foundation CAREER awards

...he inadvertent adverse effects that engineered nanomaterials may have on microorganisms, with a special focus on bacteria in engineered water systems, biofilm bacteria and beneficial bacteria versus pathogens. "Results from this research will provide a fundamental understanding of the unintentional role t...

Biofilm in Medical Technology

Transave Receives $2.2 Million Cystic Fibrosis Foundation Award for Development of ARIKACE(TM)

...eatment uses biocompatible lipids endogenous to the lung that are formulated into small (0.3 micron), neutral liposomes that enable penetration of the biofilm and are highly efficient, with a very low lipid-to-drug ratio (0.65). ARIKACE can be delivered through nebulization, which enables the small aerosol...

NanoVibronix Receives Wound Healing Indications in Europe for its PainShield(TM) Device

...so developed a unique line of catheter-based disposable ultrasound devices designed to treat catheter associated injury including pain, discomfort and biofilm formation. The first two products in this family are the UroShield(TM) for indwelling urinary catheters and the NG-Shield(TM) for indwelling Nasogastr...

Mpex Pharmaceuticals Presents New Data on MP-376 in Cystic Fibrosis

... Cmax:MIC ratios in pulmonary tissues to avoid resistance development in bacteria. -- Activity in biofilms: studies in an established in vitro biofilm system showed that levofloxacin potency was least affected compared to tobramycin or aztreonam. -- Activity in anaerobic environments: an...

Transave Announces Positive Phase II Results for Once-Daily Arikace(TM) in the Treatment of Cystic Fibrosis Patients Who Have Pseudomonas Lung Infections

...sustained release and penetration of the mucus and biofilm in the lungs, and we believe it will provide benef...ave's next-generation liposomal technology." The biofilm is a gel-like matrix in the lungs formed by coloni...eliver a drug once a day that may penetrate the CF biofilm and achieve a sustained improvement in lung functi...

Oritavancin Demonstrates Potent and Rapid In Vitro Activity Against MRSA, VRE and Other Strains of Resistant Bacteria

...ntrations of Oritavancin Kill Stationary-Phase and biofilm Staphylococcus aureus In Vitro," researchers detai...tested against in vitro models of slow-growing and biofilm S. aureus. Slow-growing bacteria and biofilms are ... S. aureus biofilms, oritavancin exhibited minimal biofilm eradication concentrations (MBEC) values between 0...

U. of Md. Researchers to Develop Devices to Revolutionize Drug Research

...each providing unique information about the sample." For example, the device will be able to take electrical, mechanical and optical measurements of biofilm (a coating created by bacteria that is the first sign of an infection). These results, collected in parallel, can then be correlated much faster than ...

Biofilm in Medical Products

SDS 200: 200 L Reservoir

Description:... Optional ASM Automatic Sanitization Module prevents bacterial growth and biofilm build-up inside the reservoir during storage Distribution pump is cont...ion Module prevents bacterial proliferation and the build-up of a bacterial biofilm on the inner surface of S.D.S. reservoirs. The ASM module contains a 25...
Company:Millipore

SDS 350: 350 L Reservoir

Description:... Optional ASM Automatic Sanitization Module prevents bacterial growth and biofilm build-up inside the reservoir during storage Distribution pump is cont...ion Module prevents bacterial proliferation and the build-up of a bacterial biofilm on the inner surface of S.D.S. reservoirs. The ASM module contains a 25...
Company:Millipore

200 L Storage & Distribution System without pump

Description:... Optional ASM Automatic Sanitization Module prevents bacterial growth and biofilm build-up inside the reservoir during storage Distribution pump is cont...ion Module prevents bacterial proliferation and the build-up of a bacterial biofilm on the inner surface of S.D.S. reservoirs. The ASM module contains a 25...
Company:Millipore

200 L Storage & Distribution System with pump

Description:... Optional ASM Automatic Sanitization Module prevents bacterial growth and biofilm build-up inside the reservoir during storage Distribution pump is cont...ion Module prevents bacterial proliferation and the build-up of a bacterial biofilm on the inner surface of S.D.S. reservoirs. The ASM module contains a 25...
Company:Millipore

SDS 350: 350 L Reservoir + Pump

Description:... Optional ASM Automatic Sanitization Module prevents bacterial growth and biofilm build-up inside the reservoir during storage Distribution pump is cont...ion Module prevents bacterial proliferation and the build-up of a bacterial biofilm on the inner surface of S.D.S. reservoirs. The ASM module contains a 25...
Company:Millipore

SDS 200: 200 L Reservoir + Pump

Description:... Optional ASM Automatic Sanitization Module prevents bacterial growth and biofilm build-up inside the reservoir during storage Distribution pump is cont...ion Module prevents bacterial proliferation and the build-up of a bacterial biofilm on the inner surface of S.D.S. reservoirs. The ASM module contains a 25...
Company:Millipore

350 L Storage & Distribution System without pump

Description:... Optional ASM Automatic Sanitization Module prevents bacterial growth and biofilm build-up inside the reservoir during storage Distribution pump is cont...ion Module prevents bacterial proliferation and the build-up of a bacterial biofilm on the inner surface of S.D.S. reservoirs. The ASM module contains a 25...
Company:Millipore

350 L Storage & Distribution System with pump

Description:... Optional ASM Automatic Sanitization Module prevents bacterial growth and biofilm build-up inside the reservoir during storage Distribution pump is cont...ion Module prevents bacterial proliferation and the build-up of a bacterial biofilm on the inner surface of S.D.S. reservoirs. The ASM module contains a 25...
Company:Millipore

Biofilm in Biological News

Veterinary college researchers explore function of biofilm in bovine respiratory disease

p>Blacksburg, Va.--Dr. Thomas J. Inzana, the Tyler J. and Frances F. Young Professor of Bacteriology in the Department of Biomedical Sciences and Pathobiology in the Virginia-Maryland Regional College of Veterinary Medicine at Virginia Tech, has been awarded a grant from the United States Departmen...

Liang receives NIH grant for biofilm research

HOBOKEN, N.J. Stevens Institute of Technology recently received a research grant from the National Institutes of Health (NIH) for the project, Functional Polymers Modified Surfaces with Biofilm Sensitizing Ability. Jun F. (James) Liang, Associate Professor in the Department of Chemistry and Chemic...

'Microfluidic palette' may paint clearer picture of biological processes

... the diameter of a pinhead. The tool can be used to study the complex biological mechanisms in cells responsible for cancer metastasis, wound healing, biofilm formation and other fluid-related processes. The advantage of the NIST system, as described in a new paper,* is that the gradients are generated by...

Test helps in fight against lung infections and for treating other life-threatening infections

...ired to treat serious, chronic infections that are biofilm based. With more than 80 per cent of infections i...e potential for this new breakthrough test, called biofilm PA™, is of immense significance to the medic...ists for these infections to cause death. Until biofilm PA™, treatment of chronic infections require...

A matter of density, not quantity

...orum-sensing metabolic processes are relevant to a number of cellular functions, including the growth of small numbers of cells at the early stages of biofilm formation or the early stages of an infection." By using a microfluidic experimental array, the team was able to isolate droplets with a volume of ...

Are you okay to kiss?

...g. "Now, we are able to grow these bacteria from saliva in an artificial biofilm, showing that there are two distinct populations at work." In the biofilm the basis of the new breath test the color difference between the Gram-positive and Gram-negative bacteria is remarkable. In the top layer of the bi...

Two-pronged model could help foil tough cystic fibrosis infections

...nas infection. "The beauty is that we are mixing FDA-approved drugs-- antibiotics and iron chelators-- to potentiate the effect of tobramycin on biofilm formation," said lead author Dr. Sophie Moreau-Marquis, a research associate. "It's an exciting translational framework that opens the door to poten...

Sugar on bacteria surface serves as base for a web of resistance

...ng studied, Pseudomonas aeruginosa, the results of biofilm development can be lethal. Chronic infection with ...the matrix, or the architectural glue that holds a biofilm together, scientists hope the research could lead ...ngled out Psl as the likely culprit in Pseudomonas biofilm creation a few years ago, but weren't certain abou...

Genes that make bacteria make up their minds

...lls living as part of a complex community called a biofilm "decide" between different physiological processes...entists to work on alternative strategies to treat biofilm related infections and may improve technologies fo... individual bacteria to "decide" whether to form a biofilm or not. "Presumably the bacteria need to achie...

No hiding place for infecting bacteria

...lls to prevent Pseudomonas aeruginosa bacteria from building a protective biofilm which enables them to avoid both the body's immune mechanisms and antibioti...P. aeruginosa uses these cell proteins as a scaffold to build a protective biofilm making these infections very difficult to treat. P. aeruginosa biofilms c...

Biofilm in Biological Technology

QSB Anti-Virulence Platform Inhibits Biofilm Formation by Staphylococcus Aureus MRSA and Candida sp

MELBOURNE, Florida, February 7 /PRNewswire/ -- QuoNova LLC, which is 88.7% owned by XL TechGroup, Inc. (AIM: XLT), has generated preliminary in-vitro data indicating high efficacy of selected Quorum Sensing Blockers ("QSB") in inhibiting biofilm formation by MRSA (methicillin-resistant Staphyl...

Pharmacy Compounds Liquid Mupirocin for the Chronic Sinusitis Patient

...est: MRSA, staph, neti-pot, biofilm, neilmed®, mupirocin, irrigation, staphylococcus aureus, staph infection, neti pot danger, netipots, biofilms, biofilm bacteria, neilmed sinus rinse, neil med, mupirocin ointment, nebulized antibiotics, sinusitis, sinusitis, chronic sinusitis, sinus headache, asl, nasa...

Transave Enters Into Cooperative Research Agreement With NIH To Study ARIKACE(TM) In Nontuberculous Mycobacteria

...eatment uses biocompatible lipids endogenous to the lung that are formulated into small (0.3 micron), neutral liposomes that enable penetration of the biofilm and are highly efficient, with a very low lipid-to-drug ratio (0.65). ARIKACE can be delivered through nebulization, which enables the small aeroso...

Scotland Highlights New Partnerships and Cutting-Edge Drug Discovery Research

... for fungal nail infection. Scottish Organizations at BIO Accuro Biologics Aquapharm Biodiscovery Ltd AvantiCell Science Ltd biofilm Limited BioOutsource Biotech Innovation and Future Health Limited Cellartis AB ClinTec International Ltd CXR Biosciences Ltd D...

Buckyballs could keep water systems flowing

...ed March 5, 2009 in the Journal of Membrane Sciences . "As the bacteria build up on these surfaces, they attract other organic matter, creating a biofilm that slowly builds up over time," Chae continued, "The results of our experiments in the laboratory indicate that buckyballs may be able to prevent th...

DiFUSION Technologies Completes Successful Testing of Antimicrobial Spinal Implant

...rted in large studies to range from 2.5% to 13%, DiFUSION has developed CleanFUZE(TM), an antimicrobial PEEK spinal interbody cage capable of stopping biofilm formation in the bone graft site and eliminating 650 types of bacteria including antibiotic-resistant bacteria such as MRSA for up to four weeks posto...

NanoVibronix Receives FDA Clearance for its PainShield(TM) MD Device

...so developed a unique line of catheter based disposable ultrasound devices designed to treat catheter-associated injury including pain, discomfort and biofilm formation. The first two products in this category are the UroShield(TM) for in-dwelling urinary catheters and NG-Shield(TM) for in-dwelling Nasogastr...

PURE Bioscience Reports Fourth Quarter and Year End Results

...C)-based products for human use. FTA has already begun initial formulation and clinical projects for FDA-regulated dermatology, wound care and medical biofilm control products containing SDC. Earlier in the year, the company signed an agreement with Rockline Industries, Inc., for North American distributio...

Transave, Inc. Secures $12.5 Million in New Financing

...e treatment uses biocompatible lipids endogenous to the lung that are formulated into small (0.3 micrometers), neutrally-charged liposomes that enable biofilm penetration and are highly efficient, with very low lipid-to-drug ratio (0.65). Arikace can be effectively delivered through nebulization since the sm...

Ondine Biopharma Announces Second Quarter 2008 Financial Results

... Vitro Photodynamic Eradication of Pseudomonas aeruginosa in Planktonic and biofilm Culture", Ondine researchers conclusively demonstrated rapid eradication of P. aeruginosa in both free-floating (planktonic) and the highly-resistant biofilm forms. Financial Review The improvement in gross margin percentage duri...

Biofilm in Biological Dictionary

Plaque

... Dental plaque is biofilm that builds up on the teeth. If not removed regularly, it can lead to dental cavities (caries) or periodontal problems . Dental plaque , a biofilm that builds up on teeth ... Mucoid plaque , a supposed thick coating of ...

Microbial mats

...d archaea. Microbial mats grow at interfaces between different types of material, mostly on submerged or moist surfaces but a few survive in... A biofilm is an aggregate of microorganisms in which cells are stuck to each other and/or to a surface. These adherent cells are frequently embedded within ...

Autotrophic

... , when its source of carbon ... Autotrophic . Heterotrophic. Organotrophic. Lithotrophic. Phototrophic. Chemotrophic ... Autotrophic N-removing biofilm reactors have been examined at the compositional ... The principle of autotrophic N removal under O2 limitation has been examined in ... Outline ...