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Bioavailable in Medical News

SGX Pharmaceuticals Submits Investigational New Drug Application for SGX523, a Highly Potent, Selective, Orally Bioavailable cMET Inhibitor

SAN DIEGO, Dec. 3 /PRNewswire-FirstCall/ -- SGX Pharmaceuticals, Inc. (Nasdaq: SGXP ) today announced that it has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration for SGX523. This compound is an internally developed, orally-bioavailable, small m...

Valensa Selects Parry Organic Spirulina as Ingredient of Choice for Premium Product Development

...Valensa share a commitment to the highest levels of quality and safety, and to delivering consumers the best nutritional value in the most convenient, bioavailable form. We are excited about the opportunity this ingredient gives us to create new, value-added products," he said. NOTE: The independent Parry Or...

The First High Performance Sports Water - AquaHydrate - to Offer Ionic Minerals Through Exclusive Agreement With Natural Foods Pioneer, Trace Minerals Research

... pristine source in the Great Salt Lake, which contains a rich abundance of minerals and trace minerals that have been balanced by nature and that are bioavailable because of their ionic form. The company now provides a complete line of more than 35 highly effective nutritional supplements including a line of cu...

Dr. David Williams Announces the Launch of a New Product--IFS Defense--for Help with Itchy Flaky Skin

... relieving chronic skin problems, naturally. By addressing the underlying cause of dry, itchy skin, Dr. Williams has been able to combine a highly bioavailable form of turmeric, which promotes a normal inflammatory response, with a nutrient scientifically named XP-828L, a natural substance found in whey prote...

Statement From Sequella Founder and CEO, Dr. Carol Nacy at the 'Stop TB' Meeting in Brazil on the Eve of World TB Day

... selected from a proprietary chemical library of over 250,000 new molecular entities with activity for a broad spectrum of infectious diseases. Orally bioavailable with excellent single-drug activity against Mycobacterium tuberculosis in vitro and in vivo , SQ609 has demonstrated synergistic activity with se...

Stunning finding: Compounds protect against cerebral palsy

...nds to human clinical trials is a lengthy and complicated process. Silverman says they next plan to make the compounds even more potent, selective and bioavailable and then envision partnering with a company that would want to develop the drugs further. ...

ViroPharma Reports Results of Phase 3 Clinical Trial for Maribavir in Bone Marrow Transplant Patients

...herapy, incidence of graft-versus-host disease, mortality and CMV disease-free survival. About maribavir Maribavir is a selective, orally bioavailable Phase 3 antiviral drug with a unique mechanism of action against cytomegalovirus and a favorable clinical safety profile to date, including no evidenc...

Rigel to Present at Keystone Symposia Conference

...day, January 25, 2009 Time: 2:30 - 4:30pm Session: Workshop 2: New Therapeutic Approaches to MS Presentation Title: The orally bioavailable Protein Kinase C Inhibitor RGE-80 can abrogate EAE disease induction and ameliorates disease in a therapeutic setting About Rigel ( http://www...

AIM Pharmakon Introduced Next Generation of Health and Longevity Products with a Unique Premium Quality Natural Liquid Calcium & Mineral Supplement Concentrate

...the product are derived through "Green Technology". The product is eco-friendly, completely natural with specific biophysiological features, bioavailable nutrients, and biodegradable components. Unique product features are- no preservatives, no artificial colors and no artificial flavors. AimCa++DONAN i...

XanGo Introduces 3SIXTY5(TM) Whole Food Nutrition Multi-Vitamin

...ntains four layers of health protection: -- 3SIXTY5 Daily Essentials -- a complete blend of essential vitamins and minerals at optimum levels in bioavailable forms for full absorption -- 3SIXTY5 Whole Food Blend -- a blend of antioxidant-packed mangosteen peel concentrate plus 12 fruits and 12 vegetabl...
Bioavailable in Medical Technology

Cardax Pharmaceuticals Nominates Clinical Candidate Heptax for Liver Disease; Heptax Ameliorates Inflammation and Oxidative Stress Related to Liver Disease and Metabolic Syndrome

...vel inflammation and oxidative stress are the mechanistic underpinnings of metabolic syndrome. The Cardax lead compound is a novel and highly bioavailable proprietary derivative of the natural dietary carotenoid astaxanthin that addresses metabolic syndrome, including liver and cardiovascular disease as ...

Arcion Therapeutics' Topical Pain Candidate, ARC-4558, Significantly Reduces Pain Caused by Diabetic Neuropathy

...lying therapies topically at the site of the pain. From a treatment standpoint, this approach has the potential to offer multiple benefits over orally bioavailable or patch-based treatments including more convenient application, uniform coverage of the affected site, lower systemic side-effects and fewer drug int...

Dendreon Presents Preclinical Data Demonstrating Activity of TRPM8 Agonist, D-3263, in Benign Prostatic Hyperplasia

.../ -- Researchers from Dendreon Corporation (Nasdaq: DNDN ) today presented preclinical data demonstrating the potential of D-3263, Dendreon's orally bioavailable small molecule, which targets TRPM8 (a transmembrane cation channel protein), to treat benign prostatic hyperplasia (BPH). D-3263 demonstrated the ab...

Cylene to Present Advances in its Oral Inhibitor of CK2 at AACR Annual Meeting

...dication - Clinical Research 12, Abstract 3599 Tuesday, April 21, 2009: 1:00 PM Discovery and characterization of CX-4945 a selective orally bioavailable small molecule inhibitor of protein kinase CK2: Phase I initiated - Experimental and Molecular Therapeutics 34, Abstract 4660 Tuesday, April 2...

ViroPharma Announces Discontinuation of Maribavir Phase 3 Study in Liver Transplant Patients

...ects that limit the use of current therapies, including suppression of bone marrow function. About maribavir Maribavir is a selective, orally bioavailable Phase 3 antiviral drug with a unique mechanism of action against cytomegalovirus and a favorable clinical safety profile to date, including no evidenc...

ProteoTech's Exebryl-1(R) Enters Human Clinical Trials for the Treatment of Alzheimer's Disease

...thological hallmark of Alzheimer's disease. Further studies are ongoing to confirm these exciting findings. Thus, Exebryl-1(R) may be the first orally bioavailable small molecule drug that affects both amyloid plaque and neurofibrillary tangle accumulation, the two major characteristic and pathological lesions of...

Emisphere Presents Dramatic Clinical Evidence Demonstrating New Approach to Vitamin B12 Supplementation

....J., July 28 /PRNewswire-FirstCall/ -- Emisphere Technologies, Inc. (Nasdaq: EMIS ) today announced new human clinical data demonstrating a new, more bioavailable oral form Vitamin B12 and a potential new avenue for addressing the problems with B12 supplementation. As demonstrated by the data, the Eligen(R) B12 ...

ViroPharma Announces Completion of Enrollment in Phase 3 Study of Maribavir in Stem Cell Transplant Patients

...rapy, incidence of graft-versus-host disease, mortality and CMV disease-free survival. About maribavir Maribavir is a potent and selective, orally bioavailable Phase 3 antiviral drug with a unique mechanism of action against cytomegalovirus and a favorable clinical safety profile to date, including no evidenc...

Dendreon Presents Preclinical Data Demonstrating Activity of Trp-p8 agonist, D-3263, in Benign Prostatic Hyperplasia

...d preclinical data demonstrating the potential of D-3263, Dendreon's orally bioavailable small molecule, which targets Trp-p8 (a transmembrane cation channel protei...of other cancers including breast, lung and colon. Dendreon has synthesized bioavailable small molecule agonists that activate the Trp-p8 ion channel and induce cel...

Rigel's R788 Slows Progression of Murine Lupus in Preclinical Studies

... potential of R788's effect on the immune cascade in an in vivo lupus model, has been published in Arthritis and Rheumatism and is titled - "An Orally bioavailable Spleen Tyrosine Kinase Inhibitor Delays Disease Progression and Prolongs Survival in Murine Lupus," (May 2008, Volume 58, No. 5, p.1433). "These res...
Bioavailable in Medical Products

Testosterone, Bioavailable & Sex Hormone Binding Globulin (Includes Total Testosterone), Females or Children

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Testosterone, Bioavailable & Sex Hormone Binding Globulin (Includes Total Testosterone), Adult Male

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

MacularProtect Complete®-S Powerful Protection for Macular & Full Body Health

Features:...REDS clinical trial Free of beta-carotene can be used by individuals who should avoid high beta-carotene intake, such as smokers Provides 10 mg of bioavailable FloraGLO® lutein and 1 mg zeaxanthin, consistent with the latest scientific findings Features comprehensive multinutrient support with over 30 k...
Company:ScienceBased Health

MacularProtect Complete® Powerful Protection for Macular & Full Body Health

Features:... overall body health Contains a blend of antioxidants and zinc at levels found to support eye health in the AREDS clinical trial Provides 10 mg of bioavailable FloraGLO® lutein and 1 mg zeaxanthin, consistent with the latest scientific findings Features comprehensive multinutrient support with over 30 k...
Company:ScienceBased Health

OcularProtect WHOLE BODY FORMULA

Features:...ecting ingredients: green tea extract, broccoli sprout extract and OptiBerry Mixed Berry Blend. Read more about these ingredients. Delivers highly bioavailable nutrient sources and standardized plant extracts for consistent delivery of active compounds Made from premium ingredients and manufactured accord...
Company:ScienceBased Health
Bioavailable in Medical Dictionary

Calcium

... nutrition ... Some practical information about calcium . Dietary factors. Evidence for benefit ... Just be aware that some sources do not have bioavailable calcium . ... About 99% of the calcium in the body is found in bones and teeth, while the ... Thus, adequate dietary calcium is a critical fa...
Bioavailable in Biological News

Scripps Florida scientists awarded $1.5M to fight major water and food parasites

...the parasite's ability to infect human tissue. In animal models, this molecule behaves beautifully in that capacity. Unfortunately, it's not an orally bioavailable compound, so right now we're working to optimize it to make it orally available." ...

Biological selenium removal: The solution to pollution?

...hylated selenium species or nano-sized elemental selenium particles. The emission of nano-sized selenium particles is problematic, as these can become bioavailable by direct assimilation or reoxidize to selenite and selenate. Dimethlyselenide and dimethyldiselenide, two species with unknown ecotoxicological long-...

Forest canopies help determine natural fertilization rates

...extremely high nitrogen fixation rates. Nitrogen fixation is an energy demanding process. Thus, when mosses are exposed to high concentrations of bioavailable nitrogen, the cyanobacteria will consume this resident nitrogen rather than expending energy on fixing new nitrogen. Thus the nitrogen content of can...

Genetically modified carrots provide more calcium

...the Proceedings of the National Academy of Sciences. Slightly altering the gene (sCAX1) to make it a more active transporter allows for increased bioavailable calcium in the carrots- , said Dr. Kendal Hirschi, professor of pediatrics-nutrition and principal investigator of the study conducted at the USDA/ARS...

High estrogen levels associated with dementia in older men

...mone levels were associated with risk of developing dementia "Levels of bioavailable testosterone were not associated with risk of cognitive decline and incident dementia," they report. "In contrast, higher levels of bioavailable estradiol were associated with an increased risk for cognitive decline and ...

New Scripps Oceanography project to study sediments and ecosystem restoration in Venice lagoon

...dying Venice's lagoon Deheyn will use luminous brittle stars, a cousin species of starfish, to determine whether contaminants in the Venice Lagoon are bioavailable (the amount of contaminants locally present and shown to be accumulated by the organism) and could potentially induce stress on the local ecosystem. ...

Transgenic plants remove more selenium from polluted soil than wild plants, new tests show

...hat we are heading in the right direction." Researchers like using the Indian mustard plant because it is very efficient at absorbing selenate, the bioavailable form of selenium in the soil. The plant is tricked into absorbing selenate because it is chemically similar to sulfate, an essential nutrient for the ...
Bioavailable in Biological Technology

Palkion Selects Novel Oral Development Candidate for the Treatment of Anemia

...ns are injectables, an oral agent, as being developed by Palkion, could be very appealing from both a commercial and clinical perspective as an orally bioavailable agent might expand usage and improve patient compliance as well. "This sooner than expected start of preclinical development studies is an affi...

ChemoCentryx Identifies Novel Small Molecule C5aR Antagonist

...ne Payment from GlaxoSmithKline MOUNTAIN VIEW, Calif., May 5 /PRNewswire/ -- ChemoCentryx, Inc., today announced that it has identified an orally bioavailable small molecule antagonist of the C5a receptor, CCX168, as a candidate for clinical development. The acceptance of the molecule as a development candi...

AEterna Zentaris Presents Two Posters on its PI3K Inhibitor Compound, AEZS-126, at AACR Annual Meeting

...ed at the American Association for Cancer Research (AACR) Annual Meeting in Denver, Colorado. Poster #3705 Entitled, "AEZS-126, a new orally bioavailable PI3K inhibitor with antitumor effects", I. Seipelt, S. Baasner, M. Gerlach, M. Teifel, J. Fensterle, L. Blumenstein, G. Mueller and E. Guenther, the p...

AEterna Zentaris To Present Data on Anticancer Compounds AEZS-112 and AEZS-126 at AACR Annual Meeting

...on April 18-22, 2009 at the Colorado Convention Center in Denver, Colorado. AEZS-126 (Poster #3705) - Entitled, "AEZS-126, a new orally bioavailable PI3K inhibitor with antitumor effects", I. Seipelt, S. Baasner, M. Gerlach, M. Teifel, J. Fensterle, L. Blumenstein, G. Mueller and E. Gue...

InterMune to Present Abstracts on HCV Protease Inhibitor ITMN-191 and HCV Development Program at the EASL Meeting

...NS5B Polymerase Inhibitor ITMN-8020 Enhances Replicon Clearance and Reduces the Emergence of Drug Resistant Variants . Discovery of Potent, bioavailable HCV NS3/4A Inhibitors that Display Unimpaired Activity Against an NS3 Sequence Variant Associated with Resistance to Linear Tetrapeptides and Macrocyc...

Sequella Receives SBIR Funding Grant from the NIH for Further Development of Tuberculosis Drug SQ609

... selected from a proprietary chemical library of over 250,000 new molecular entities with activity for a broad spectrum of infectious diseases. Orally bioavailable with excellent single-drug activity against Mycobacterium tuberculosis in vitro and in vivo , SQ609 has demonstrated synergistic activity with se...

AIM Pharmakon (API) Announced a New Proprietary Premium-Quality Natural Concentrated Liquid Calcium and Mineral Supplement Now Available Direct to Consumers

...s eco-friendly, completely natural with specific biophysiological features, bioavailable nutrients, and biodegradable components. Unique product features are: no pr...vatives, no artificial colors and no artificial flavors. Adequate intake of bioavailable calcium helps to achieve peak bone mass, strong teeth, and prevents the bon...

Dendreon Presents Preclinical Data Validating Anti-Tumor Activity of D-3263, a Trp-p8 Agonist

... where it is over-expressed in BPH and prostate cancer, as well as a range of other cancers including breast, lung and colon. Dendreon has synthesized bioavailable small molecule agonists that activate the Trp-p8 ion channel and induce cell death. About Dendreon Dendreon Corporation is a biotechnology company...

SuperGen Reports 2008 Second Quarter Financial Results

... (AML) xenograft models. -- MP-470, an early clinical-stage multi-targeted tyrosine kinase inhibitor and Rad51 suppressor, was shown to be bioavailable and well-tolerated in a first in human study (Abstract No. 4083). The presentation entitled, "MP-470, a potent oral Rad51 suppressor is...

Aegera Therapeutics collaboration with Human Genome Sciences leads to the initiation of a Phase 1 clinical trial with lead IAP inhibitor HGS1029 and receipt of first milestone payment

...ing therapeutically significant kinases including JAK2 and Bcr-Abl, and is currently in Phase I clinical studies; - AEG33773 is a novel, orally bioavailable small molecule developed to treat painful diabetic neuropathy and is in Phase I clinical studies. Website: http://www.aegera.com ...
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