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Bextra in Medical News

$89 Million Proposed Class Action Settlement Provides Consumers and Insurers With Money Back for Celebrex and Bextra Purchases and Reimbursements

WASHINGTON, April 29 /PRNewswire-USNewswire/ -- A federal court in San Francisco has granted preliminary approval to a proposed settlement with Pfizer Inc. ("Pfizer") about the marketing of the prescription drugs Bextra and Celebrex. The settlement in the case called In re Bextra and Celebrex Mar...

Canada May Not Permit Bextra To Reenter Market

Health Canada has announced a ban on the anti-inflammatory drug Bextra, meant for those who suffer from arthritis. The benefits derived from the drug were outweighed by the cardiovascular risks, including the possibility of // triggering strokes and heart attacks, according to an expert safety pane...

FDA Approves New Arthritis Drug, Bextra

The US Food and Drug Administration has approved a new drug for treating osteoarthritis. Osteoarthritis is a progressive deterioration in the cartilage of certain joints. Unlike rheumatoid arthritis, which is an inherited autoimmune disease, osteoarthritis results from overuse of joints, and can be...

Potential lung disease biomarkers yield clues to COX-2 inhibitor side effects

...f drugs has also been shown to reduce colorectal polyps, a precursor to colorectal cancer. But two blockbuster COX-2 inhibitors, Vioxx (rofecoxib) and bextra (valdecoxib), were pulled off the market after reports that they elevated the risk of heart attack, stroke and death in users. Celebrex (celecoxib) is...

Study Sheds Light on Painkillers' Heart Risk

...ve been found to increase the risk of heart attack and stroke. Three cox-2 inhibitor NSAIDs have been marketed in the United States. Two of them -- bextra and Vioxx -- were withdrawn from the market earlier this decade because of their association with an increased risk of heart attack and stroke. A thir...

Vioxx Settlement Puts Painkillers Back in the Spotlight

...nce again. Cox-2 inhibitor drugs such as Vioxx, bextra and Celebrex were initially hailed as a means of t...o increased risk for heart attacks. In April 2005, bextra was pulled because of similar fears, as well as ev...r patients, too, experts added. Since Vioxx and bextra were taken off the market, rates of gastrointestin...

Vioxx Ban Tied to Rise in Serious GI Trouble

...althDay News) -- Pulling the painkillers Vioxx and bextra off the market to spare patients' hearts may have ...ing, in Boston. Cox-2 inhibitors such as Vioxx, bextra and Celebrex are a subset of a larger group of pai...y Celebrex remains on the market. The Vioxx and bextra withdrawals may have come at a cost, however, as A...

Merck's Pain Reliever Arcoxia Rejected by US Federal Advisory Panel

... also following evidence that it increased the patients' risk of heart attacks and strokes. G.D.Searle and Company too withdrew a COX-2 inhibitor, bextra because of similar concerns. These newly developed drugs for treatment of inflammation selectively block an enzyme called COX-2. Blocking this enz...

Green signal for new drug for arthritis given in Canada

...ciated with intake of other drugs used clinically for arthritis and of the same class .Those who have used other drugs in its class, such as Vioxx and bextra have reported heart problems in the past. . The pharmaceutical company Novartis announced the sanction of this COX-2 drug Prexige which will incide...

Celebrex- pros and cons

... risks associated with Celebrex is being given a lot of importance by doctors. Celebrex belongs to the Cox-2 inhibitors, painkiller family. Vioxx and bextra are the other members that are no longer available in the market due to their connection with heart disease. Celebrex is not as dangerous as Vi...
Bextra in Biological News

New understanding of COX-1 and COX-2 enzymes could revise classification of pain meds

...on with University of Pennsylvania researchers. The study was initiated to explore the biochemistry associated with COX-2 inhibitors such as Vioxx, bextra and Celebrex, which are now associated with an increased incidence of heart attack and stroke. Researchers looked at mice that were genetically modifi...

FDA Announces Series of Changes to the Class of Marketed Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

...fits and minimizing their risks." FDA has asked Pfizer, Inc. to withdraw bextra (valdecoxib) from the market because the overall risk versus benefit profil...brex (celecoxib) label. Pfizer has agreed to suspend sales and marketing of bextra in the U.S., pending further discussions with the agency. Pfizer has agreed...
Bextra in Biological Technology

Why are new drugs failing?

... The FDA's recent decision to pull Pfizer Cox-2 inhibitor bextra from the marketplace clearly jolted both Pfizer and the market. Pfizer was ... poor job of surveillance once drugs are on the market? The FDA's action on bextra was clearly in part due to public criticism of perceived FDA laxness. Th...
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