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Bcl in Medical News

Tumour risk increased by tissue protective protein

...ich are genetically dissimilar with respect to the bcl gene expression. The strain of mice, which produced less bcl protein, developed less number of tumors in contra...hat produced more of Bcl. Moreover, mice with more bcl protein production on an average had larger tumour...
Bcl in Medical Technology

Gemin X Biotechnologies Announces Publication in Blood of Positive Preclinical Data of Lead Compound in Mantle Cell Lymphoma

...Velcade(R)), a proteasome inhibitor, such that MCL cells became sensitized to low doses of bortezomib. Bortezomib was shown to induce the pro-survival bcl member, Mcl-1, which causes resistance to the drug. Inhibition of Mcl-1 by GX15-070, in contrast, overcame this resistance. This positive preclinical ...
Bcl in Biological Technology

RT-PCR Primers for the Study of Apoptosis

...tages, the family of Bcl-2 proteins is present as the antagonists of cell death. When the death signal is presented to the cell, the expression of bcl proteins is down-regulated, which helps the death signal to trigger the activation of the ICE protease family. Consequently, the cell undergoes a ...
Bcl in Biological Dictionary

Multi-gene family

...rms of myosin heavy chains, coded for by a multi - gene family PUBMED:2806546. ... ... is accelerated by all six members of the antiapoptotic bcl family " ... to clone members of a multi - gene family , homologous genes from different species, ... ... bacterium Pseudoalteromonas halopl...

Apoptosis

... Apoptosis by Measuring ... ... central regulators of intrinsic apoptosis . pathways. 5. Regulatory mechanisms in apoptosis signalling. 5.1 The bcl ... 1. The development of the term apoptosis ... Apoptosis . Apoptosis ... The Apoptosis Laboratory is a research group in the Institute ...
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