Baseline

Once Monthly Dosing: How Much of a Competitive Advantage is it? Rheumatologists Provide Insight in the Baseline Report of LaunchTrends(TM): SIMPONI(TM)

EXTON, Pa., June 4 /PRNewswire/ -- BioTrends Research Group, Inc. announces the release of the baseline LaunchTrends (TM): SIMPONI report. The survey was completed by U.S. Rheumatologists in May 2009, just days after the FDA announced approval for SIMPONI (golimumab). Once monthly dos...

Experts establish baseline for civic engagement among retirees

The rise of retired people seeking active participation in their communities has led researchers to define this new aspect of American life. As a result, civic engagement can now be considered a distinct retirement role, according to an article in the latest issue of The Gerontologist (Volume ...

Analysis of Six Clinical Trials Finds EPZICOM(R) Effective in Treatment-Naive HIV Patients With Both High and Low Baseline Viral Loads

MEXICO CITY, Aug. 7 /PRNewswire-FirstCall/ -- GlaxoSmithKline (NYSE: GSK) announced that a retrospective analysis of six clinical trials found that anti-HIV regimens containing EPZICOM (abacavir + lamivudine) were effective in treatment-naive patients regardless of baseline viral loads. One of...

Researchers Produce First Nationwide Study of Homeless in ERs

...s nationwide." Despite that, more diagnostic tests were ordered than for other patients. "This may be because emergency physicians needed to do baseline blood work because the homeless patient didn't have a primary care doctor," Dr. Oates explained. "Or it could be because the homeless population may b...

AMICAS Reports Financial Results for the Second Quarter Ended June 30, 2009

...l tools for evaluating the Company's performance that are the same as management uses in its own evaluation of the Company's performance, as well as a baseline for assessing the future earnings potential of the Company. While GAAP results are more complete, the Company offers investors these supplemental metr...

FDA Approves INVEGA(R) SUSTENNA(TM) for the Acute and Maintenance Treatment of Schizophrenia

...d to one of three fixed doses of INVEGA SUSTENNA for a period of 13 weeks. The primary endpoint of this study was the change in total PANSS score from baseline to endpoint. Each of the three additional acute treatment studies involving INVEGA SUSTENNA met its primary endpoint of significantly improving PANSS ...

Baseline in Medical Technology

Radius' Investigational Bone Anabolic Agent, BA058, Increased Bone Mineral Density (BMD) at Key Fracture Sites in Phase 2 Clinical Trial in Postmenopausal Osteoporosis

...domized to Forteo(R) or one of three doses of BA058 (20, 40, or 80 micrograms), or matching placebo. The study's co-primary endpoints were change from baseline in lumbar spine BMD and changes in anabolic bone markers. BMD is a measurement of mineralized bone tissue used to diagnose osteoporosis and to help de...

Labopharm files New Drug Submission with Health Canada for novel antidepressant

... of sleep. The primary efficacy endpoint of the study was to compare the change in the Hamilton Rating Scale for Depression (HAMD-17) total score from baseline to the end of the study in the trazodone group versus the placebo group. Statistical significance was achieved for the primary endpoint (p value of 0....

Video: FDA Approves INVEGA(R) SUSTENNA(TM) for the Acute and Maintenance Treatment of Schizophrenia

...of three fixed doses of INVEGA(R) SUSTENNA(TM) for a period of 13 weeks. The primary endpoint of this study was the change in total PANSS score from baseline to endpoint. Each of the three additional acute treatment studies involving INVEGA(R) SUSTENNA(TM) met its primary endpoint of significantly improvi...

Shire Reports Positive Results From First of Three Phase III Trials of velaglucerase alfa for Type 1 Gaucher Disease and Provides Important Updates on Interactions With FDA

...th patients benefiting from a clinically important and statistically significant (p<0.0001) increase in mean hemoglobin concentration compared with baseline after receiving velaglucerase alfa at 60 U/kg IV every other week for 12 months. Statistically significant improvements compared with baselines were a...

Study Results Show That Minimally Invasive Therapy is Successful for Over Two-Thirds of Stroke Patients Treated Outside the Standard Eight-Hour Window

...whose mean time from last seen well to t reatment was 15 hours. On the standard National Institute of Health Stroke Scale (NIHSS) -- a test that uses baseline data to determine severity of a stroke and projected outcome -- participants registered a mean score of 15 (any score over 10 is associated with a se...

S.C. Medical Home Pilot for Diabetes Enrolls 1,110

... In the first three months, case managers hired for the project have contacted 60 percent of the eligible patients to explain the concept, to gather baseline health data, and to encourage them to use an online portal that contains tools that help manage their disease and enable them to have "e-visits" with ...

Baseline in Medical Products

17-Hydroxypregnenolone Baseline Specimen

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

OQAS Optical Quality Analysis System

Description:...comparative studies, monitoring of cataract formation, comparative studies of different surgical techniques, and most importantly having an objective baseline of your patients optical quality. This objective analysis of optical quality can be used as an adjunct to your current subjective assessment of optica...
Company:Visiometrics

Plateletworks Combo-25 Kit

Description:... collagen or ADP as the agonist. The procedure is simple and no special sample preparation is required. A 1.0 cc whole blood sample is added to both a baseline and an Agonist Reagent Tube. Both tubes are run on the Ichor analyzer. Kit includes 25 ADP and 25 Collagen Agonist Reagent Tubes...
Company:Helena Laboratories

Ichor Hematology Analyzer

Description:...tandard CBC with platelet count plus platelet aggregation within five minutes. The test is simple. A fresh whole blood sample is added to both an EDTA baseline and a Collagen or ADP agonist tube. All tubes are run on the Ichor hematology analyzer. CBC, including platelet count, is available within minutes. Pl...
Company:Helena Laboratories

Lyphochek Drug-Free Serum

Description:... Lyphochek® Drug Free Serum can serve as a drug-free baseline for HPLC analysis or as a negative control....
Company:Bio-Rad Laboratories

Innova CO-48 Personal-Sized Direct Heat CO2 Incubator, for on-or-under bench

Description:...izes contamination risk. Integral viewing window means cultures need not be disturbed. HEPA filtered CO2 inlet; accurate IR CO2 sensing with automatic baseline reset simplifies maintenance. Extra-large display screen provides immediate access and control to on-board programming, alarm functions and real-time ...
Company:New Brunswick Scientific Co., Inc.

Baseline in Medical Dictionary

Transplant rejection

...ecipient of an ... Stanford Team Prevents Kidney Transplant Rejection Without Drugs (April 24, 2002) ... transplant recipient consists of 1) baseline therapy to prevent rejection , and 2) ... B, Therapeutic application of CTLA41g to transplant rejection . ... aakp - American Association of K...

Thromboembolism

...mbolism (PROACT) II study found ... HJM, Vinuela F. CT visualization of intracranial arterial thromboembolism . Stroke. ... Clotting: to provide baseline measurements and to exclude problems pre ... Negative scan: Venous thromboembolism remains so likely that a venogram is needed. ... ...

Oral health

...f the Dental Home ... many pediatricians report that oral health was not addressed as part of their ... of care for oral health requires a baseline level of knowledge to facilitate ... Since the early 1970s, the cases of dental caries in permanent teeth have ... Additionally, some people...

Meningioma

...ginate in ... Biology and clinical features of meningioma . Classification of brain tumors ... PCI increases incidence of meningioma by 10X baseline rate. ... Cavernous sinus meningioma represent a scenario where SRS is particularly useful ... The meningioma is the neurosurgeon's "friend"...

Lipoprotein

...ong-term overfeeding on plasma lipoprotein levels in identical twins. Plasma leptin response to an epinephrine infusion in lean ... ... from baseline in the ratio of Low Density Lipoprotein cholesterol/High Density ... the participant has a mean low density lipoprotein cholesterol level ... ...

Erosion

...ccurrence influenced by climate and geology, as well as ... Erosion . Chemical Contaminants. Fish Consumption ... Erosion Prevention ... Alaska baseline Erosion Assessment. Study Findings and Technical Report. March 2009 ... FINDINGS AND TECHNICAL REPORT. 5.0 APPROPRIATE RESPONSES TO EROSION . ...

Baseline in Biological News

Scripps expedition provides new baseline for coral reef conservation

An ambitious expedition led by scientists at Scripps Institution of Oceanography at UC San Diego to a chain of little-known islands in the central Pacific Ocean has yielded an unprecedented wealth of information about coral reefs and threats from human activities. The exploration of four atolls...

A new baseline of invasive plants in Isabela

Charles Darwin Foundation (CDF) botanists have published a list of all the introduced plants growing in Puerto Villamil, Isabela Island, the third largest town in Galapagos. 261 species were recorded, 39 of which were found growing wild. Despite 95% of the archipelago falling under the Galapago...

K-State researchers say after-school programs should promote activity, healthy nutrition

...evices to measure their physical activity. After a baseline year, the HOP'N program was implemented at four of...their regular programming as a project control. baseline findings of the study showed that, on average, the... preferences of overweight children. During the baseline year, the researchers also found that there was a ...

1 in 6 health workers won't report in flu pandemic -- study by Ben-Gurion U. researchers

.... The study concludes that in the context of pandemic influenza planning, the EPPM provides a useful framework to inform nuanced understanding of baseline levels of and gaps in local public health workers' response willingness. Within local health departments, "concerned and confident" employees ar...

UTMB study identifies women at risk of gaining excessive weight with injectable birth control

...owed 240 women ages 16-33 who used DMPA for up to three years. Researchers looked at several potential predictors of weight gain, including age, race, baseline obesity prior to DMPA use, lifestyle variables such as smoking and exercise level, and weight gain at six months. They found that those who had gained...

Red List overlooks island species

...ered by Red List criteria for threatened species. As invertebrates usually have a smaller distribution area than large vertebrates and birds "the same baseline criteria cannot be used for birds and snails, for example", explains the biologist. "More than 2,000 species, most of which are in a good state of ...

Baseline in Biological Technology

InterMune Reports Second Quarter 2009 Financial Results and Business Highlights

...study of ITMN-191 in combination with Pegasys and ribavirin. After 14 days of triple combination therapy, the median change in HCV RNA from baseline exceeded 5 log10 in five of the six dosage cohorts, and was -5.4 log10 and -5.7 log10 in the best performing q12h and q8h cohorts, respectively. ...

Amicus Therapeutics Announces Second Quarter 2009 Financial Results

...idney biopsies. An analysis of the Phase 2 and Phase 2 extension study biopsies using the improved methodology demonstrated that all of the evaluable baseline samples had detectable interstitial capillary GL-3 and that reductions were observed in eight of the nine responders. It is expected that app...

International Milk Genomics & Human Health Symposium Speaker Program Announced

...erstanding of the biological values of milk, creating tools for an interactive, Web data exchange, coordination of pre-competitive research to develop baseline data, and providing a foundation for the development of exclusive/competitive research. For more information about the Consortium, visit www.milkgeno...

Elagolix Successful in Six Month Lilac Petal Study; Safety and Efficacy Confirmed in Patients With Endometriosis

...e from baseline, femur; -0.66% mean change from baseline, spine). The 250 mg once daily dose, as expected, had slightly greater percentage change from baseline at month six (-1.0% femur, -1.6% spine). The 150 mg once daily BMD profile in this Lilac Petal Study is consistent with that previously demonstrated i...

SAPHRIS(R) (asenapine) Meets Primary Endpoint in Long-Term Extension Study in Patients With Predominant, Persistent Negative Symptoms of Schizophrenia

...olanzapine in the reduction of negative symptoms as measured by change from baseline to Day 365 in the NSA-16 total score, the primary endpoint of the study. B...ally significantly greater change in NSA-16 total score from the core study baseline after one year of treatment, the primary prespecified endpoint of the exten...

Evidence for a New Genetic Link to Therapeutic Efficacy for Alzheimer's Disease

...ther AC-1202 or placebo for 90 days, with efficacy assessments performed at baseline (Day 0), Day 45, Day 90 and after a two week washout from their assigned pr...ariant of the APOE gene (E4(-)), demonstrated significant improvement from baseline values in the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) and...

Baseline in Biological Products

Mutation Surveyor from SoftGenetics, LLC.

Description:...en processing single direction sequence traces. Mutation Surveyors detection sensitivity has been enhanced to report similar peaks that are buried in baseline noise of both the forward and reverse traces, alerting researchers to the possible presence of mutations buried in the background noise. Mutation Su...
Company:SoftGenetics, LLC.

ICS-1500 Standard Integrated IC System from Dionex Corporation

Description:...n today get to your customer ahead of schedule. When you need to perform sample analysis right on the first run, dont compromise on hardware. When baseline stability matters, column heating will pave the way for better reproducibility and stability. Extremely durable PEEK materials remain contamination-...
Company:Dionex Corporation

Custom Epitope Peptide Microarray from LC Sciences

Description:...entration may be used to obtain their titration curve. Established microarray analysis software is used to extract detectable signals after non-linear baseline correction of quantitative calculations using reference signals and statistical analyses. LC Sciences LC Sciences is a genomics and proteomics comp...
Company:LC Sciences

NeuroCyte - Rat Neural Stem Cell Kit from Orion BioSolutions, Inc.

Description:...ceeds (far right). With Neuro Cyte-NSC intracellular FACS phenotyping kit, you can quantify a decrease in nestin expressing cells with an increase in baseline TUJ1/b-tubulin III neuroblasts and neurons. Orion also provides a focused microarray for gene expression analysis, Stem Chip. ...
Company:Orion BioSolutions, Inc.

Baseline in Biological Dictionary

Species

...erger. It was given an R rating for... Working to enumerate all known species of organisms on Earth (animals, plants, fungi, and microbes) as the baseline dataset for studies of global biodiversity. The nature of species is controversial in biology and philosophy. Biologists ... In this entry, thr...

Quantitative trait loci

...ssays, summaries, research information, and more. ... Quantitative Trait Loci Summary ... QTL resources - Quantitative trait loci maps, baseline white blood cell count, platelet count, mapping of PLTP, links to other publications. formed quantitative trait locus / loci (QTL) analys...

Phase variation

...andom phase variation . due to noise pk-pk. Random amplitude variation . due to noise pk-pk ... Abstract – The phase variation from a 300-m baseline 11.2 GHz interferometer was ... In Figure 5 we have the phase variation seen by the interferometer and the ... ...