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Baculovirus in Medical News

Protein Sciences Corporation Appoints New Board of Directors

...ingredients in all of the firm's products are recombinant proteins that are manufactured, using its patented protein expression technology, based upon baculovirus and insect cell technology. In response to the current health emergency declared by the Department of Health and Human Services, PSC is developin...

Experimental Flu Vaccine Appears Promising in Early Tests

...nant HA expressed in insect cells by a recombinant baculovirus (rHA0). The clinical trial was conducted at three ...the available expression technologies, recombinant baculovirus is especially well suited for production of influe...f the HA protein in insect cells using recombinant baculovirus also avoids the need to work with potentially path...
Baculovirus in Medical Technology

Pre-clinical Data on Recent Advances with HIV VLP Vaccine Presented at AIDS Vaccine 07 Conference

...OCKVILLE, Md., Aug. 22 /PRNewswire-FirstCall/ -- Novavax, Inc. (Nasdaq: NVAX ) announced today the oral presentation of a paper entitled "Recombinant baculovirus Derived HIV-1 Virus-Like Particles Elicit Potent Neutralizing Antibody Responses" at the AIDS Vaccine 07 conference in Seattle by Dr. Weimin Liu, Univ...

ANA380 Exhibits Activity In Vitro Against Multiple Clinically Relevant Hepatitis B Virus Mutants

...trains encoded polymerases resistant to lamivudine, adefovir, entecavir or telbivudine. Replicate HepG2 cell cultures were infected with HBV DNA using baculovirus vectors and were exposed to different concentrations of each drug for seven days. Viral DNA then was extracted and quantified. EC50 values, which were...
Baculovirus in Biological News

Surprise in the organic orchard -- a healthier worm in the apple

...l crop protection worldwide. The proverbial worm in the apple, the codling moth caterpillar, has been controlled in European orchards for years with a baculovirus called codling moth granulovirus (CpGV). But in southwest Germany, some organic apple growers noticed that the virus was losing its effectiveness. Pes...

New influenza vaccine takes weeks to mass produce

...ing them into a baculovirus. Specific host cells are then infected with the baculovirus and produce recombinant hemagglutinin (rHA). Phase II clinical trials show...rom any of these strains," says Wang. "Starting from a stocked recombinant baculovirus bank, a closely matched vaccine can be massively produced within 2 weeks." ...

Stolen gene allows insect virus to enter cells

...s in fruit flies remains to be answered. At some point, perhaps after retroviruses had sprinkled host genomes with multiple copies of the f gene, a baculovirus picked it up through recombination. Unlike retroviruses, baculoviruses don't insert their genes into their hosts' genomes. They do steal genes, howeve...

Gene therapy advance treats hemophilia in mouse models

...e hepatocytes in the mice, the team took the disabled protein coat from the baculovirus Autographa californica and put it on to a modified type of lentivirus calle...icle efficiently bound to receptors on the liver cells because the modified baculovirus coat serves as a "key" that fits into the "lock," or receptor. The percenta...

Influenza vaccine uses insect cells to speed development

... Using a strategy involving a genetically modified baculovirus and caterpillar cells scientists from Protein Sciences Corporation have been able to speed up a key step in the development of an experimental cell-ba...
Baculovirus in Biological Technology

Commercial Manufacturing of H1N1 'Swine Flu' Vaccine Underway

...hereafter. The vaccine, called PanBlok(R), is made using PSC's proprietary baculovirus and insect cell manufacturing technology. PSC believes that PanBlok is the... manufactured, using its patented protein expression technology, based upon baculovirus and insect cell technology. PSC's lead product is FluBlok(R), a season...

Protein Sciences Announces Signing of a Forbearance Agreement With Emergent BioSolutions

...ingredients in all of the firm's products are recombinant proteins that are manufactured, using its patented protein expression technology, based upon baculovirus and insect cell technology. In response to the current health emergency declared by the Department of Health and Human Services, PSC is developin...

PacificGMP and LigoCyte Pharmaceuticals Announce cGMP Manufacturing Collaboration

...Inc. Under the collaborative agreement, PacificGMP produced master cell and baculovirus banks and will provide storage services under cGMP (current good manufactur...e are pleased that LigoCyte chose PacificGMP to produce the master cell and baculovirus banks that will be used to produce their next-generation, intra-muscular no...

Insect Cell Culture Using a BioFlo 110 Benchtop Bioreactor

...e (NBS Catalog No. M1291-0000) was used to control the feeding schedule. Insect cells are used to produce a variety of proteins by utilizing the baculovirus Expression Vector System (BEVS). Insect cell lines such as Sf9, Sf21, Hi-5, etc., are proven to express high levels of end products. ...

Continuous-Elution Electrophoresis for Purification of the Baculovirus-Expressed Coronavirus Structural Proteins, Rev A

...(N), and spike (S), were expressed in a baculovirus expression system. A method for rapid p...tion was 0.5 mg/ml, or 8% of the initial baculovirus lysate. The recombinant TGEV S-protein (1...tion was 0.15 mg/ml or 2% of the initial baculovirus lysate. Discussi...
Baculovirus in Biological Products

pAcAB4 Baculovirus Transfer Vector from BD Biosciences Pharmingen

Description: The pAcAB4 vector is a 10.0 kb Autographa californica (AcNPV) polyhedrin locus-based vector that contains two copies of the AcNPV polyhedrin promoter and two AcNPV p10 promoters. Downstream of the first p10 promoter is a Sma I cloning site, followed by polyhedrin locus-derived termination sequences...
Company:BD Biosciences Pharmingen

Bac-to-Bac Baculovirus Expression System from Invitrogen

Description: ...
Company:Invitrogen

Anti-gp64 Antibody, Unconjugated from Novagen

Description:... on the surface of infected cells as early as 8-24 hours post-infection. This forms the basis of the FastPlax Titer Kit, which allows determination of baculovirus titers in just 25-48 hours. The FastPlax Antibody can also be used to detect gp64 on Western blots....
Company:Novagen

BacPlaque Agarose from Novagen

Description:... Agarose overlays are commonly used in baculovirus plaque assays. Many commercial "DNA grade" agaroses either contain contaminants that are toxic to insect cells or lack the physical characteristics re...
Company:Novagen

TriEx Insect Expression Medium from Novagen

Description:... TriEx Sf9 Cells and TriEx Insect Cell Medium are recommended for protein expression from pTriEx baculovirus constructs. This cell/medium combination has been selected based on rapid, vigorous cell growth and high protein expression levels observed specifical...
Company:Novagen

4% Agarose Gel from Invitrogen

Description:... Agarose for baculovirus plaque assays which allow optimal growth of plated insect cells....
Company:Invitrogen

Baculovirus Expression System with Gateway Technology from Invitrogen

Description:... The baculovirus Expression System with Gateway™ Technology i...ter. The expression cassette is transferred to the baculovirus genome (bacmid DNA) by site-specific transposition...r transfection and expression in insect cells. The baculovirus Expression System with Gateway™ Technology o...
Company:Invitrogen

GST Expression and Purification Kit from BD Biosciences Pharmingen

Description:... pAcGHLT-A,B,C baculovirus Transfer Vector Set pAcGHLT-XylE baculovirus Control Vector Thrombin Powder Thrombin Dilution Buffer Protease Inhibitor ...
Company:BD Biosciences Pharmingen

Cell Culture Training Courses from European Collection of Cell Cultures (ECACC)

Description:...lture and a Level II course which focuses on more specialist areas such as planning and management of a cell culture laboratory, primary cell culture, baculovirus and large scale cell culture....
Company:European Collection of Cell Cultures (ECACC)

BacMagic™ DNA Kit from Novagen

Description:... The BacMagic™ DNA Kit provides a positive selection for creating baculovirus recombinants in preparation for recombinant protein expression in insect ce... the target coding sequence replaces the BAC sequence. Only the recombinant baculovirus can replicate, producing a homogeneous population of recombinants. In addit...
Company:Novagen
Baculovirus in Biological Dictionary

Shuttle vector

...' or convey genes from one to ... pNTAP Shuttle vectors (A, B, and C) ... Shuttle Vector . Get Quote Supplier ... pFastBacâ„¢ vector and The baculovirus shuttle vector (bacmid), bMON14272 (136 kb) ... Shuttle , vector ,biological ,biology dictionary,biology terminology,biology terms,biology abb...

Expression Vector

... system include bacterial expression system, yeast expression , ... The baculovirus expression vector system (BEVS) is an eukaryotic system that ... The.... Gene Expression and Cloning Vector Kits. QPCR and PCR Kits ... The baculovirus Expression Vector System (BEVS) is a convenient and versatile ... Simul...
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(Date:4/17/2014)... scientists and their partners have found that their proprietary ... transmission of multiple sexually transmitted infections (STIs) in both ... virus 2 (HSV-2), and human papillomavirus (HPV). The USAID-funded ... is effective against multiple strains of HIV, and has ... three viruses of at least eight hours prior to ...
(Date:4/17/2014)... therapy improves general blood flow and alleviates muscle ... researchers at the University of Illinois at Chicago. ... print in the Archives of Physical Medicine ... vascular function in people who had not exercised, ... of their level of physical activity. , Improved ...
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(Date:4/16/2014)... Ariz. April 15, 2014 The Translational Genomics ... at their annual Founders Dinner for their support of ... event took place March 28 in Scottsdale. , Catherine ... Ivy Foundation, received TGen,s John S. McCain Leadership Award, ...
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(Date:4/17/2014)... cells in bone marrow need to produce hydrogen sulfide ... according to a new study from the Center for ... Dentistry of USC. , Professor Songtao Shi, principal investigator ... produced by the cells governs the flow of calcium ... signals that results in osteogenesis, or the creation of ...
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(Date:4/17/2014)... in France have hit on a novel method ... the correct and most effective treatment possible., Kidney ... western and developing world. If left untreated, apart ... renal failure and other complications. In many patients ... Clearly a more effective pathological approach to diagnosis ...
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