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Bactericidal in Medical News

USC Chemical Engineer Launches Virucide, Bactericidal That Can Kill 99.9% of Germs and Help Combat Swine Flu

LOS ANGELES, April 30 /PRNewswire/ -- With the current global outbreak of the SWINE FLU and Mexico representing its Epicenter, World Health Officials are seeking ways to combat the continued spread of the unpredictable virus. U.S. Federal and Global health officials are currently working on a Comb...

Most Important Factors Driving Usage of Antibiotics in the ICU Setting are Availability in Intravenous Formulation, Activity Against Key Gram Negative Pathogens, Drug Interactions and Bactericidal Activity

Intensive Care Setting Is Characterized by Lower Level of Usage Restrictions, According to a New Report from AMR and Decision Resources MALVERN, Penn. and WALTHAM, Mass.,Dec. 15 /PRNewswire/ -- Arlington Medical Resources (AMR) and Decision Resources find that the most important factors t...

ConvaTec Launches Versiva(R) XC(R) Campaign and Best Practice Statement

... Healing Society Meeting; April 28-May 1, 2007; Tampa, FL. Newman GR, Walker M, Hobot J, Bowler P. Visualisation of bacterial sequestration and bactericidal activity within hydrating Hydrofiber((R)) wound dressings. Biomaterials. 2006;27(7):1129-1139. Jones SA, Bowler PG, Walker M. Antimicrobial ...

Medizone International, Inc. Has Filed for Patent Protection for Its AsepticSure(TM) Hospital Sterilization System

...tive work done by our science and engineering teams has proven these new and innovative combinations of technology when combined have greatly enhanced bactericidal kill rates with all of the pathogens tested so far. This is not just pumping ozone gas into a room. This patent filing not only identifies a number ...

Medizone International, Inc. (MZEI.PK) Announces it has Established its Own BSL2A Certified Laboratory Located in Innovation Park, Queen's University at Kingston, Ontario, Canada.

...Corporation as it proceeds down what is now a clear path to commercialization with its lead product, AsepticSure(TM). Given the outstanding range of bactericidal kill rates we have achieved to date ( 4.4 log /99.994% to 5 log /99.999%) with the pathogens most often associated with hospital derived infections, i...

Medizone Announces That Its AsepticSure(TM) Development Program is Reaching Objectives on Two Fronts

...g several procedural refinements in this second round resulted in levels of bactericidal action well above what was expected. Indeed, breaking through the 5 log ba...hnological development still to be introduced in this series of trials, the bactericidal ceiling for our system is now unclear, but well above what we ever expected...

Medizone Announces a Second Round of Trials Have Begun.

...irs for Medizone stated, "Our first round of trials using this technology produced results that exceeded our expectations in demonstrating significant bactericidal effects against C-difficile, E-coli, Pseudomonas aeruginous, MRSA and VRE, the main causative agents of hospital derived nosocomial infections. With ...

Trius Presents New Data on Torezolid Antibiotic for Treatment of Methicillin-Resistant Staphylococcus Aureus (MRSA) Infections

...ted. Poster presentations on TR-701 also highlighted data characterizing torezolid's pharmacodynamics, high intracellular concentrations and resulting bactericidal activity. Human Phase 1 clinical studies showed that oral torezolid, administered at doses from 200 to 400 mg once a day over 21 days, is safe and wel...

China Sky One Medical, Inc. Obtains Production Rights for Two Additional Drugs

...ctivitis and trachoma; -- Ofloxacin suppositories for the treatment for bactericidal vaginitis and Oflcoxacin gel for the treatment of bactericidal colpitis; -- Nasal drops for the treatment of allergic rhinitis and sin...

The Environmentally Friendly 'Superbug' Killer

...t surface disinfection technologies, but a truly new technology with demonstrable superiority in a number of key areas: 1. Contact times -- 1 minute bactericidal (including MRSA 'Superbug', E. Coli and VRE) -- 1 minute Virucidal (including HIV, Hepatitis C, Hepatitis B, Influenza A and Polio) -- 5 minutes...
Bactericidal in Medical Technology

Trius Announces Positive Results From Phase 2 Clinical Trial of Torezolid in Patients With Complicated Skin and Skin Structure Infections

...is class. Advantages of torezolid over linezolid include: 4-8 fold greater potency than linezolid in vitro and in vivo In vivo bactericidal activity Activity against all clinically important, gram-positive, drug-resistant strains including those resistant to linezolid Activ...

Novexel to Present Four Posters at the 19th European Congress of Clinical Microbiology and Infectious Diseases in Helsinki

...nal infections with NXL104 in combination with ceftazidime. The poster provides in vitro data showing that a ceftazidime/NXL104 combination is rapidly bactericidal against a range of beta-lactamase-producing strains of Enterobacteriaceae, including E. coli, and Klebsiella. Data presented also showed that one of t...

Novexel's NXL104/ceftazidime Combination Commences Second Phase II Clinical Trial in Hospital Patients With Complicated Intra-Abdominal Infections (cIAIs)

...er an independent development program, Forest Laboratories (NYSE : FRX) will combine NXL104 in a treatment regimen with Forest's ceftaroline, a novel, bactericidal injectable broad spectrum cephalosporin. Ceftaroline is being developed as a therapeutic agent for the treatment of gram-positive pathogens including ...

Nanoemulsion Kills Highly Resistant Bacteria Found in Patients With Cystic Fibrosis

...pediatrics at the University of Michigan . "The nanoemulsion we tested was bactericidal against all but two of 150 bacterial strains, regardless of their levels of...ated with available antibiotics." The nanoemulsion also demonstrated bactericidal activity in the presence of cystic fibrosis sputum and against bacterial bi...

Phico Therapeutics Receives GBP1 Million Award From the Wellcome Trust to Take Anti-MRSA Nasal Product Through Early Clinical Trials

...ady demonstrated last year in several studies, including some carried out in conjunction with the UK's Health Protection Agency, that PT1.2 is rapidly bactericidal against more than 200 clinical S. aureus and MRSA isolates, spanning the known MRSA types in Europe and the US. Indeed in the speed of kill assay, SAS...

Lytix Presents LTX-109 Anti-Microbial Data at ICAAC

...tX-109 into the clinic in during the second half of 2009." LTX-109 is a novel synthetic antimicrobial pepitidomimetic (SAMP) drug with a rapid bactericidal mode of action that can effectively synthesized in scalable, low-cost chemical reactor systems. About Lytix Biopharma AS Lytix Biophar...

Novexel's NXL104/ceftazidime Combination Commences Phase II Clinical Trial in Hospital Patients With Complicated Urinary Tract Infections

...er an independent development program, Forest Laboratories (NYSE : FRX) will combine NXL104 in a treatment regimen with Forest's ceftaroline, a novel, bactericidal injectable broad spectrum cephalosporin being developed as a therapeutic agent for the treatment of gram-positive pathogens including methicillin resi...

Forest Laboratories Announces Positive Results from Phase III Clinical Studies of Ceftaroline for the Treatment of Complicated Skin and Skin Structure Infections

...ncreased healthcare costs.(4) About Ceftaroline Ceftaroline is a novel, bactericidal injectable broad-spectrum cephalosporin being developed as a therapeutic ag...s well as common gram-negative organisms. Ceftaroline has also demonstrated bactericidal activity against vancomycin-resistant Staphylococcus aureus (VRSA), linezol...

Replidyne Provides Strategic Update

...m of action to block an essential step in the DNA replication process. Based on current preclinical data, the series exhibits oral bioavailability and bactericidal activity against all major classes of antibiotic-resistant Gram-positive bacteria, including clinically-relevant resistant phenotypes such as methicil...

Sanofi Pasteur Receives FDA Approval of Meningococcal Vaccine for Children

...ceived Menomune-A/C/Y/W-135 vaccine. In addition, compared to Menomune-A/C/Y/W-135 vaccine, Menactra(R) vaccine resulted in longer-term persistence of bactericidal antibody, production of high avidity antibody, and the establishment of immune memory. No clinically significant adverse events were identified after ...
Bactericidal in Medical Products

Serum Bactericidal Assay

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Surgicel Nu-Knit Absorbable Hemostat

Description:...The only oxidized regenerated cellulose hemostat line, surgicel absorbable hemostat delivers a unique combination of effectiveness, absorbability, and bactericidal protection....
Company:Ethicon, Inc.

Surgicel Absorbable Hemostat Family

Description:...The only oxidized regenerated cellulose hemostat line, surgicel absorbable hemostat delivers a unique combination of effectiveness, absorbability, and bactericidal protection....
Company:Ethicon, Inc.
Bactericidal in Medical Dictionary

Neutrophil

...ek lifespan in the ... INTRODUCTION The polymorphonuclear neutrophil (PMN) is the primary defense ... EVALUATION FOR NEUTROPHIL DYSFUNCTION. bactericidal killing assay. Interpretation ... neutrophil 1. one of the three granular leukocytes having a nucleus with three to five lobes connected by th...

Intracellular

...yocardial Ischemia/Reperfusion Is ... Information about intracellular in the free online ... Intracellular Adhesion Molecules. Intracellular bactericidal activity ... ... signals to intracellular effectors, particularly protein ... This drug is widely used in studies aimed at dissecting intra...
Bactericidal in Biological News

Fractional dose of scarce meningitis vaccine may be effective in outbreak control

...e. In 2004, a randomized clinical trial of 750 healthy volunteers (2-19 years old) took place in Uganda. Their immune response, assessed by serum bactericidal activity (SBA), was measured for 1/5 and 1/10 doses compared to a full dose. SBA response and safety/tolerability using 1/5 dose were comparable to a ...

Proteomics study yields clues as to how tuberculosis might be thwarting the immune system

... by the University of New Mexico's Vojo Deretic and his research group), we speculate that mycobacteria may produce specific factors to counteract the bactericidal effect of autophagy activation." The Bertozzi and Keasling research groups are now examining whether certain mycobacterial products can modulate ma...

Best treatment identified to reduce deadly Staph infections

...he products had some antibacterial effectiveness against MRSA bacteria, the OSU study found, but only the benzethonium chloride compound had a genuine bactericidal effect meaning it reduced the number of bacteria by a factor of 1,000 against all four of the tested MRSA strains. Its worth noting that theres n...

Boston University biomedical engineers find chink in bacteria's armor

...enues of research. Currently, three classes of bactericidal antibiotics are used to target different bacterial...e, A Common Mechanism of Cellular Death Induced by bactericidal Antibiotics, appears in the September 7 issue of C...ge, you can potentiate or enhance the lethality of bactericidal antibiotics. This highlights the value of taking a...

Clean skies=faster global warming?

...on upregulates HIF-1. In fact, upregulation of HIF-1 enhances expression of bactericidal agents and killing of bacteria. This reveals that a novel approach to tr...tic immunomodulation." ### TITLE: HIF-1alpha expression regulates the bactericidal capacity of phagocytes View the PDF of this article at: https://www.the-...

Eliminating bacterial infections out of thin air

...on upregulates HIF-1. In fact, upregulation of HIF-1 enhances expression of bactericidal agents and killing of bacteria. This reveals that a novel approach to tr...tic immunomodulation." ### TITLE: HIF-1alpha expression regulates the bactericidal capacity of phagocytes View the PDF of this article at: https://www.the-...

Ants, not evil spirits, create devil's gardens in the Amazon rainforest, study finds

...nts we tested," the authors write. "To our knowledge this is the first record of an ant using formic acid as a herbicide--although it is known to have bactericidal and fungicidal properties." The ants employ a very effective system of lethal injection, notes Gordon, associate professor of biological sciences a...

Edible bivalves as a source of human pathogens: signals between vibrios and the bivalve host.

...io interactions with both cellular and soluble components of the bivalve immune system in the light of the capacity of bacteria to evade the hemolymph bactericidal activity and to develop pathogenic effects in the bivalve host." The authors describe their data obtained with an in vitro model of Vibrio cholerae...

Roots Engage in Underground Chemical Warfare

...ients, plant roots secrete a wide variety of compounds that affect other nearby roots, as well as insects and microbes. But because it goes on unseen, bactericidal root activity has not been extensively investigated—until now. Using the model plant Arabidopsis thaliana, a relative of garden-variety cabbage, Jorge...
Bactericidal in Biological Technology

Northern Antibiotics Presents New Data on Novel Polymyxin Compounds at the Joint ICAAC/IDSA 2008

...he challenge organism. As low a dose as 1 mg/kg (body weight) of NAB739, given at 1h postinfection and repeated at 3 h postinfection, displayed potent bactericidal effect. The bacterial counts in the treated animals were 4.8 log10 lower in the mice treated with NAB739 than in the untreated control mice. Further...

Positive Study Results for Ceftaroline Phase III Clinical Study for the Treatment of Complicated Skin and Skin Structure Infections Presented at ICAAC / IDSA

...tz and colleagues showed that ceftaroline has the greatest overall in vitro bactericidal activity against community-associated MRSA (CA-MRSA), vancomycin-intermedia...s well as common gram-negative organisms. Ceftaroline has also demonstrated bactericidal activity against vancomycin-resistant Staphylococcus aureus (VRSA), linezol...

Arpida's iclaprim MAA Accepted for Review by EMEA

... European Union for the treatment of complicated Skin and Soft Tissue Infections (cSSTI). Iclaprim is a hospital antibiotic drug candidate with potent bactericidal (killing) activity against MRSA and an extended range of important pathogens. The iclaprim MAA contains data from 15 clinical studies, including two...

Arpida Submits New Drug Application for Intravenous Iclaprim for Treatment of Skin Infections

...ation (FDA). Arpida has requested a Priority designation for the review of the NDA. Iclaprim is a synthetic diaminopyrimidine which exhibits a rapidly bactericidal action against an extended spectrum of pathogens, including multidrug-resistant bacteria. The iclaprim NDA contains data from 15 clinical studies, i...

Researchers Pinpoint Best Treatment to Reduce Deadly USA300, MRSA Staph Infections

...st in infectious diseases and an author of the study. Dr. George P. Allen joined Bearden and Christensen as the third author. "Staphaseptic remained bactericidal for 24 hours, which surprised me," said Christensen. "Usually you see an initial kill, which is followed by the bacteria growing again. But Staphasept...

First Patients Enrolled in Phase II Trial With Intravenous Iclaprim in HAP/VAP/HCAP

..., life-threatening condition with a high medical need. We believe that iclaprim could have a high potential in this indication based on its potent and bactericidal action on MRSA and its good distribution in those lung compartments where the key respiratory pathogens reside." Dr Islam added: "Moreover, we are v...

Arpida Presents Preclinical and Clinical Data on Iclaprim at ICAAC

...and nosocomial Staphylococcus aureus (poster E-904) and it showed good activity against streptococci and enterococci. E-906: Iclaprim exhibited rapid bactericidal activity against several clones of MRSA (E-MRSA, VISA, VRSA) predominant in community and hospital infections. Iclaprims Post Antibiotic Effect (PAE) ...

Astellas and Theravance Report Additional Telavancin Data at 47th Annual ICAAC

...n. In the more than 2,700 clinical isolates tested, telavancin was one of the most potent agents. When evaluated in light of other data on bactericidal effect in staphylococci infections, the totality of data suggest clinical activity across the range of Gram-positive bacteria. About ATLAS ...

New Licence for Cubicin(R) (daptomycin), the First in a Novel Class of Antibiotic, is Announced Today for the Treatment of Serious Bloodstream and Heart Infections Caused by the Most Problematic UK Organisms, Including MRSA

... England, September 13 /PRNewswire-FirstCall/ -- - Physicians Welcome New Option for Potentially Life Threatening Disease - Daptomycin has a Rapidly bactericidal Mode of Action The launch of daptomycin for the treatment of both methicillin-sensitive and resistant Staphylococcus aureus (MSSA and MRSA) bloodstre...

Targanta Therapeutics to Have Significant Presence at 47th Annual ICAAC Meeting

... spores About Oritavancin Oritavancin is a novel semi-synthetic lipoglycopeptide antibiotic candidate with potent bactericidal (killing) activity against a broad spectrum of gram-positive bacteria. The product candidate has been tested in over 1500 patients and has completed t...
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