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BCG in Medical News

BayCare Named to Top 100 Best Companies To Work For in Florida by Florida Trend Magazine

...ational, statewide and regional basis. Through its thorough workplace assessment, utilizing employer questionnaires and employee-satisfaction surveys, bcg identifies and recognizes companies that have been successful in creating and maintaining workplace excellence. For more information, please visit ww...

Wounded Warrior Project (WWP) Expands Board of Directors

...rd members, bringing the total of the expanded group to fourteen. Retired Army Captain Anthony K. Odierno, Retired First Lieutenant Andrew Kinard and bcg Partners Inc. Chief Administration Officer Roger C. Campbell will hold these new positions. "We felt it was important to expand the Board of Di...

Bioniche Phase III Clinical Trial with Urocidin(TM) Progressing Well

... III Registration Trial Bioniche plans to conduct a second registration trial that will directly compare the efficacy and safety of Urocidin with bcg in the first-line treatment of non-muscle-invasive bladder cancer. In September, 2007, the Company announced that an agreement had been reached with t...

Genetic analysis may predict risk of invasive bladder cancer

..., and colleagues evaluated a panel of 59 single nucleotide polymorphisms in 35 major inflammation genes in all participants that had been treated with bcg therapy, the current treatment standard for non-muscle invasive bladder cancer. If a patient had a genotype containing the variant allele of the i...

Genetic variants predict recurrence of bladder cancer, patient survival

...ombined with chemotherapy or immunotherapy such as bcg injection. Overall, the recurrence rate is around ...perienced a recurrence after receiving maintenance bcg therapy. Only 22 percent of patients with the vari... with the same treatment. The results suggest that bcg may be more effective when administered to individ...

Bioniche Completes Recruitment in First Phase III Clinical Trial with Urocidin(TM)

...elerated Approval program. Bioniche plans to conduct a second registration trial that will directly compare the efficacy and safety of Urocidin with bcg in the first-line treatment of non-muscle-invasive bladder cancer. In September, 2007, the Company announced that an agreement had been reached with t...

China Medicine Announces Record Fourth Quarter and 2008 Results

...urchasing and installing equipment for the production of rADTZ. The Company also spent $2.9 million as the deposit on the purchase of the ownership of bcg (Bacillus Calmette-Guerin) vaccine for the prevention of infection in bladder cancer patients post surgery and $2.3 million on exclusive distribution ...

TB breakthrough could lead to stronger vaccine

... University of Texas Medical School at Houston. bcg is a live but weakened form of a bacterium, M. bov...tronger immune response. However, tuberculosis and bcg have evasive mechanisms that prevent the developme...Center at Houston investigated mechanisms by which bcg evades immune stimulating mechanisms and devised t...

New discovery gives tuberculosis vaccine a shot in the arm

...million, almost 2 million die. The disease can spread through the air, and it usually affects the lungs. Without treatment, tuberculosis is fatal. The bcg vaccine for tuberculosis is used in many countries, but not generally recommended in the United States. The vaccine is not completely effective in pre...

Bioniche Phase II Bladder Cancer Trial Results Published in The Journal of Urology

...ston, Ontario, Canada. "Safety concerns exist with bcg because it is a live mycobacterium and its use is ...ancer is specifically refractory (unresponsive) to bcg are receiving a formulation of Mycobacterial Cell ...rectly compare the efficacy and safety of MCC with bcg in the treatment of non-muscle-invasive bladder ca...
BCG in Medical Technology

Aeras, Crucell and South African Tuberculosis Vaccine Initiative Announce Encouraging Preliminary Results of Tuberculosis Vaccine Clinical Trial in South Africa

...ecember 2007 and focuses on the immunogenicity and safety of two AERAS-402/Crucell Ad35 boost doses administered at three to six month intervals after bcg priming in healthy adults. "The world urgently needs a new TB vaccine, and although we are still in the early stages of clinical trials, the preli...

Study Shows: New Blood Test Proven Six Times More Effective For Tuberculosis Control

...kine called interferon-a. QFT accurately measures the interferon-a response in a sensitive enzyme assay. Unlike the TST, QFT is unaffected by previous bcg vaccination and most other mycobacteria. QFT requires only one patient visit, is a controlled laboratory test, and provides an objective, reproducible...

Halozyme Therapeutics Completes Enrollment in Chemophase Phase I/IIa Clinical Trial for Superficial Bladder Cancer

...s of mitomycin were less than 1/40th of the levels reported to be predictive of suppression of white blood cell production. The study was conducted at bcg Oncology in Phoenix, Arizona under the supervision of Donald L. Lamm, MD, the principal investigator. The American Cancer Society estimates that ther...

Indevus Receives Approvable Letter From FDA for VALSTAR(R) for Bladder Cancer Therapy

... protocols and for additional data on the manufacturing process. "VALSTAR offers an effective alternative for bladder cancer patients who have failed bcg therapy and are not candidates for immediate cystectomy," stated Glenn L. Cooper, M.D., chairman and chief executive officer of Indevus. "The FDA requ...

Intercell AG: Novel tuberculosis Vaccine Shows Promising Immunogenicity and Safety Profile

...tand alone schedule, as well as in combination with previous exposure(s) to bcg or other closely related mycobacteria. It seems that our decision to combin...for 10-15 years. However, when the protective effect decreases, yet another bcg vaccination does not provide sufficient TB protection. Therefore, a new typ...
BCG in Medical Products

NMP22® BladderChek® Kit (1-test kit)

Features:...of>0.993 with a mean recovery of 99%. Unlike other tests, NMP22 values are not affected by gross hematuria and common intravesical treatments such as bcg or thiotepa. The dual monoclonal antibody assay is supplied in microwell format. Results are read on a microplate reader at 490 nm. ...
Company:Matritech, Inc.

NMP22® BladderChek® Kit (24-test kit)

Features:...of>0.993 with a mean recovery of 99%. Unlike other tests, NMP22 values are not affected by gross hematuria and common intravesical treatments such as bcg or thiotepa. The dual monoclonal antibody assay is supplied in microwell format. Results are read on a microplate reader at 490 nm. ...
Company:Matritech, Inc.
BCG in Medical Dictionary

BCG

Bacillus Calmette-Guérin is a vaccine against tuberculosis that is prepared from a strain of the attenuated (weakened) live bovine tuberculosis bacillus, Mycobacterium bovis, that has lost its virulence in humans by being... The Boston Consulting Group ( BCG ) is a global management...
BCG in Biological News

Boosting The BCG Vaccine To Beat Tuberculosis

Tuberculosis remains a major global health threat. Although more than 3 billion doses of the BCG vaccine have been administered to fight tuberculosis, the ability of the BCG vaccine to protect adults is very limited, as is its efficacy against newly emerging isolates. In a study appearing online ...

Team identifies a molecular switch linking infectious disease and depression

...n many parts of the world to prevent tuberculosis. bcg produces low-grade, chronic inflammation in mice, ...okines, in the blood and brain. Mice exposed to bcg display the normal symptoms of illness (lack of ap...lation in the mouse brains showed that exposure to bcg increased expression of IDO and two cytokines know...

Research identifies type of vaccine that holds promise in protecting against TB

...ticipants received the investigational recombinant bcg vaccine. Researchers compared five immune func... continue as scientists test a similar recombinant bcg vaccine that expresses the same and additional key...e World Health Organization recommends the current bcg vaccine for infants in developing countries shortl...

Clinical trial for new tuberculosis vaccine

... Kaufmann, Director at the Max Planck Institute for Infection Biology. "The bcg tuberculosis vaccine, which was developed by French researchers, is the mos...frequently administered live vaccine in the world," says Kaufmann. However, bcg (short for the bacterium Bacillus Calmette-Gurind) is now frequently ineffe...

Cornell researcher seeks clues to how tuberculosis infects cells

...ainst tuberculosis known as Bacillus Calmette-Guerin (BCG). It found that the two bacteria may each respond differently to the same stimuli and that bcg appears less capable of protecting itself once inside a macrophage. The findings are consistent with the reduced virulence of BCG, which is key to its...

Agilent Technologies Introduces First Commercial Mouse Microarray for Comparative Genomic Hybridization Research

... threat. Although more than 3 billion doses of the bcg vaccine have been administered to fight tuberculosis, the ability of the bcg vaccine to protect adults is very limited, as is i...e devise a strategy to boost the immunogenicity of bcg and describe a novel vaccine strain with high effi...

Researchers Discover Ancient Origins Of Tuberculosis-causing Bacteria

... threat. Although more than 3 billion doses of the bcg vaccine have been administered to fight tuberculosis, the ability of the bcg vaccine to protect adults is very limited, as is i...e devise a strategy to boost the immunogenicity of bcg and describe a novel vaccine strain with high effi...

New vaccine protects more effectively against tuberculosis

...line drugs. A vaccine against tuberculosis, termed bcg is available which, however, fails to protect agai...ficacious protection against tuberculosis than the bcg vaccine currently in use. This new vaccine induces...nt and vaccination. The new genetically engineered bcg could provide an efficacious measure against this ...
BCG in Biological Technology

WuXi PharmaTech (NYSE: WX) Honored Among the BCG 50 Local Dynamos

SHANGHAI, China, April 28 /Xinhua-PRNewswire-FirstCall/ -- WuXi PharmaTech (NYSE: WX ), a leading pharmaceutical, biotechnology and medical device research and development outsourcing company with operations in China and the United States, today proudly announced that it has been listed among...

US College Students Needing TB Testing Now Have the Benefit of QFT(TM)

...alse-positive results due to cross-reactivity with bcg vaccine and commonly encountered environmental non...ence countries as many of them are vaccinated with bcg at birth. Reading a TST response is subjective and...ore accurate than the TST as it is not affected by bcg vaccination exposure to non-tuberculous mycobacter...

Quintiles Consulting Business Expands

...nd outsourcing strategies. McKemey was most recently a Principal with the Boston Consulting Group (BCG), working in the Health Care practice and the bcg Strategy Institute. Since 2000, he has helped large pharmaceutical clients optimize product research and development and commercialization through set...

Sanofi Pasteur and Statens Serum Institut Team Up Against Tuberculosis

...t tuberculosis and for SSI. "SSI is one of the world's leading producers of bcg and has for more than a century worked within the field of prevention and c...nt or young child becoming exposed to an infectious case are high. Although bcg is effective in protecting infants against childhood forms of the disease, ...

Cellestis Receives FDA Approval for Blood Test for Detecting Tuberculosis

...abling remote location blood collection. It measures immune responses to peptides that simulate M. tuberculosis proteins, which are not present in the bcg vaccine or most non- tuberculosis mycobacteria. Thus, QFT(TM) is 99% specific and a positive test result is strongly predictive of true infection with...

Indevus Receives Approvable Letter From FDA for VALSTAR(R) for Bladder Cancer Therapy

... protocols and for additional data on the manufacturing process. "VALSTAR offers an effective alternative for bladder cancer patients who have failed bcg therapy and are not candidates for immediate cystectomy," stated Glenn L. Cooper, M.D., chairman and chief executive officer of Indevus. "The FDA requ...
BCG in Biological Definition

Vaccine

...based vaccines include tetanus and diphtheria The live tuberculosis vaccine is not the contagious TB strain, but a related strain called " bcg "; it is used in the United States very infrequently. A number of innovative vaccines are also in development and also in use: Conjugate - cert...
BCG in Biological Dictionary

Polyprotein

...e ... To ascertain that the Mtb72F polyprotein is specifically recognized by the ... One advantage of using a polyprotein vaccine rather than bcg in humans is that ... The polyprotein precursor is further processed into structural and nonstructural ... Polyprotein processing activity of...
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