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Awry in Medical News

Brain’s "Default Mode" Awry in Schizophreni

The 'default mode,' or baseline condition when the brain is idling, is not properly coordinated in patients with schizophrenia and this aberrant activity// may be caused by poor connectivity between brain networks, a Yale School of Medicine researcher reports. Co-author Godfrey Pearlson, M.D....

Diets bad for the teeth are also bad for the body

...his is unfortunate, he adds, because dental diseases really may be the most noticeable and rapid warning sign to an individual that something is going awry with his or her diet. "Dental problems from poor dietary habits appear in a few weeks to a few years," Hujoel explains. "Dental improvement can b...

Alterations in brain's white matter key to schizophrenia, UCLA study shows

... developing young people and high-risk adolescents develop during this period right before the disease would be expected to manifest. Something may go awry with the developmental process during this period that might contribute to the onset of the disorder." The other important finding, she said, wa...

Most common brain cancer may start in neural stem cells

... fact that the new insights into p53 may help explain. The results found in mice add specific new insights to an unfolding picture of how genes go awry to result in brain cancer. Scientists recently learned that certain genes and pathways of cell action are altered in glioblastoma. One of these key al...

Most common brain cancer may originate in neural stem cells

... fact that the new insights into p53 may help explain. The results found in mice add specific new insights to an unfolding picture of how genes go awry to result in brain cancer. Scientists recently learned that certain genes and pathways of cell action are altered in glioblastoma. One of these key al...

Early Detection of Melanoma Plus Regular Skin Exams is Vital For Beating Disease

...udied to treat the more advanced stage melanomas." One potential therapy involves targeting specific drugs to specific genes that are known to go awry in the development of melanoma. There are multiple genes involved in melanoma progression from local tumor to disseminated disease. And, on a molecula...

Penn Medicine, CHOP researchers demonstrate first common genetic risk factors for autism

...autism, along with a rarer genetic change that contributes to some cases of autism," Schellenberg said. "This work yields important clues on what goes awry during development in children with autism and will help us focus on what is the cause of autism at a molecular level." "It is very compelling to f...

Study reports success in treating a rare retinal disorder

...ack the retina, resulting in progressive vision loss and eventual blindness. AIR is like other autoimmune diseases in which the immune system goes awry and begins to attack healthy tissue. The patients in the current study were treated with various combinations of immunosuppression medications to coun...

CSHL neuroscientists propose project to comprehensively map mammalian brain circuits

...autism or schizophrenia Perhaps the most exciting aspect of such a brain mapping project is its likelihood to deepen our understanding of what goes awry at the circuit level in neuropsychiatric illnesses. At present, scientists are lacking data of this type with which to work on theories of disease ca...

2 NYU scientists named Howard Hughes Medical Institute's Early Career Scientists

... testing hundreds of potential drugs that might prevent malignant T cells from reaching the nervous system. At the same time, he is learning what goes awry in blood stem cells that transform into leukemic T cells. Such insights may provide even more ways to combat deadly blood cancers. Dr. Dasen's res...
Awry in Medical Technology

Novel Photoconductive Life Science Research Innovation Enables Rapid, Reproducible, and Non-Invasive Cellular Excitation

...e mechanisms underlying cellular structure/function relationships. Additionally, it will enable scientists to better elucidate how these mechanisms go awry during disease states and potentially how to better address (and/or prevent) the disease state (and/or injury) following onset. Further, the diagnosti...
Awry in Biological News

Newly found enzymes may play early role in cancer

...the levels of DNA methylation on genes. "Methylation is a cellular process that is required for healthy cell growth and development, but it can go awry in cancer and diseased cells," says Brad Cairns, Ph.D., HCI investigator and professor of oncological sciences at the University of Utah. "You can thi...

Brain enzyme may play key role in controlling appetite and weight gain

...accordingly keeping the body's caloric intake in balance with calories burned. To learn more about these nutrient-sensing pathways and how they go awry in metabolic disorders, researchers at Einstein focused on an enzyme called p70 S6 Kinase 1, or S6K, which plays a role in regulating the growth and p...

Penn scientists discover cells reorganize shape to fit the situation

...lls bend, they reorganize their cytoskeleton, and as they reorganize their internal skeletons, the cells further adjust their shape. Cell shape gone awry has been implicated in some forms of cancer. In the future, one potential implication of Tran's findings is that it might be possible to rescue certai...

Making flies sick reveals new role for growth factors in immunity

...e both the heart and the lymph glands in the fly originate from the same tissue (cardiogenic mesoderm), he postulated that when heart development goes awry in fruit fly Dpp mutants that the lymph glands might also be affected. "One of the functions of the lymph gland in fruit flies is to produce blood...

Clue to genetic cause of fatal birth defect

...ective in human anencephaly is not yet known, but the discovery that the deletion of HSD17b7 in the mouse causes anencephaly suggests this gene may be awry in the human disease. "This opens up very exciting possibilities for understanding human anencephaly, and, perhaps, someday being able to provide ...

UC Davis researchers discover new drug target for inflammatory disease

...binds to two integrins labeled alpha-V-beta-3 and alpha-4-beta-1, causing them to rapidly multiply and boosting an immune system response already gone awry due to disease. "We have known for a while that this protein is elevated with inflammation," said Yoshikazu Takada, UC Davis professor of dermatol...

New master switch found in the brain that regulates appetite and reproduction

...ntrol feeding and fertility. Judith Altarejos Ph.D., first author on this study, had been trying to understand human energy balance, and what can go awry to promote obesity, diabetes and other metabolic syndromes. In this study, she looked at the signals that travel from body fat to the brain, informing...

UCLA researchers develop new PET scanning probe that will allowing monitoring of the immune system

...nal Nature Medicine, enables scientists to monitor the immune system at the whole body level in 3D as it tries to fight some cancers or when it goes awry as it does in autoimmune diseases. Researchers created the small molecule, called FAC, by slightly altering the molecular structure of one of the ...

Carnegie Mellon develops computer model to study cell membrane dynamics

...mately, understanding the dynamics of vesiculation is key to advancing the design of anti-viral therapies or understanding how protein processing goes awry within a cell and leads to disease, Deserno said. Deserno and his team created a computer simulation of a cell membrane with a lipid bilayer ...

Research explores role of hydrogen peroxide in cell health

...ce, he said. The scientists said that understanding this protective mechanism that keeps cells healthy may one day help reveal how the process goes awry in disease. They will continue the research by studying how the structural change may affect how Prx interacts with other proteins. ...
Awry in Biological Technology

W.M. Keck Foundation Awards $1 Million to Hutchinson Center Scholar to Study How Cells Go Awry

SEATTLE, Aug. 3 /PRNewswire/ -- Anyone touched by the ravages of cancer knows the rapidly growing, opportunistic cells don't play fair. But in order to expose exactly how cancer cells cheat their host, scientists must first study the rules governing the orderly cooperation of normal cell...

NEWSWEEK: Media Lead Sheet/December 10, 2007 Issue (on newsstands Monday, December 3).

...derwood reports on memory loss and the ways people can keep their minds sharper than ever. There are many hypotheses about why our powers of recall go awry over time, but it's clear that both committing new information to memory and retrieving it become more difficult. Now scientists are busy looking into...

Scientists create colorful 'brainbow' images of the nervous system

...rons." Equal parts pointillism, fauvism, and abstract expressionism, the resulting images could also help scientists identify how brain wiring goes awry in many different diseases. Brainbow could also help track the complicated development of the mammalian nervous system, currently understood only in g...
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