Women With Atypia Nearly Eight Times More Likely to Develop Breast Cancer
Washington, June 30 (ANI): A new study has found that women with at least three sites of cellular atypia
in breast tissue are nearly eight times more likely than average women to develop breast cancer.
Several earlier studies have shown that atypical hyperplasia (also called atypia) in br...
Long-term L-carnitine supplementation prevents development of liver cancer
...-neoplastic lesions in liver tissues including clusters of hepatocytes with atypia
and an increased proliferative rate, diffuse bridging fibrosis and nodule formation, bile ducts with marked reactive atypia
showing nuclear enlargement, high nuclear/cytoplasmic ratio and prominent n...
Alternating mammography and MRI may be best for high-risk women
...were considered to be at high risk if they had hereditary breast and ovarian cancer syndrome, a personal history of breast cancer, a biopsy indicating atypia
or lobular carcinoma in situ (LCIS), or a 20 percent or higher lifetime risk of developing breast cancer, as estimated by the Gail model.
In the al...
Breast cancer risk varies in young women with benign breast disease, Mayo Clinic researchers say
...-proliferative disease were only slightly at increased risk (1.2 times, or .2 percent higher than normal) and women with proliferative disease without atypia
had a risk that was doubled. A family history of breast cancer increased risk in these two groups of patients, but only slightly, the researchers say....
Risk assessment tool not reliable predictor for some women at high risk of breast cancer
...ncerns have atypia. About 25 percent of those with atypia
will develop cancer within 25 years.
Mayo Clin...esearchers tested the Gail model in 331 women with atypia
who had benign breast biopsies at Mayo Clinic betw... a coin flip in predicting which of the women with atypia
would develop invasive breast cancer.
Estrogen Supplements May Raise Odds of Benign Breast Disease
... succession of conditions, with benign proliferative breast disease without atypia
(cell abnormalities) sometimes being followed by proliferative disease with atypia
before the development of in situ (localized) cancer.
This study did not...
COX-2 expression is marker for cancer development in some benign breast biopsies
The research team discovered that women whose atypia
tissue expressed COX-2 enzymes were more likely to...
Specifically, 20 years after a biopsy in which atypia
was found, 31 percent of women with high levels of COX-2 in their atypia
sample had developed breast cancer, versus 14 perc...
Inflammation and drugs to control this activity studied in a variety of tumors sites
...vels, to predict who among the group of women with atypia
would develop breast cancer and develop ways to se...chemistry methods. Forty-one of the 235 women with atypia
developed breast cancer over roughly a 15- to 20-y...test group and will continue to profile women with atypia
who did and who did not develop breast cancer in a...