New data showed Actos prevented progression of atherosclerotic plaque volume in patients
Chicago, IL, March 31, 2008 New data from a clinical trial using intravascular ultrasound (IVUS) technology found that in patients living with type 2 diabetes, ACTOS® (pioglitazone HCl) reduced the atherosclerotic burden in the coronary arteries compared to glimepiride, and prevented progress...Another Breather For People At Atherosclerotic Risk
The disease of the elite is fast getting everywhere. Atherosclerosis is a big problem and health hazard these days. Finding a solution in this direction is yet another study. The study states that supplementation of B vitamins can reduce the risk of atherosclerosis // (plaque build-up on the blo...Researchers Develop Device For Detecting Atherosclerotic Plaques
Researchers from Cedars-Sinai Medical Center had developed a device that will use light emissions from body tissues to detect the inflammation that is //part of plaque formation in the condition of atherosclerosis. Now, in a study involving laboratory rabbits, a device that stimulates, collect...Immunoglobulin Can Predict Some Diabetic Complications
... and renal failure). If increased urine IgM excretion does reflect advanced atherosclerotic vascular disease, clinical trials would be justified to test whether modifying atherosclerotic factors also decrease mortality and incidence of renal failure in diabetic ...TriReme Medical, Inc. Receives CE Marking for Glider(TM) PTCA Dilatation Catheter
...ompany. TMI is based in California and dedicated to the development and manufacturing of novel stent technology and other devices for the treatment of atherosclerotic disease at or near bifurcations. In April 2009, TriReme received CE mark for its Antares(R) SX stent system. Antares(R) is a main vessel stent ...Prescient Medical Receives Frost & Sullivan Product Innovation of the Year Award
...prophylactic treatment of vulnerable plaques. Rajesh further noted that "the vProtect(TM) Luminal Shield should revolutionize the management of atherosclerotic lesions and prove to be a boon for interventional cardiologists and -- most importantly -- for patients by improving their quality of life and outcome...Carotid Artery Sections React Differently to Plaque
...ium and fibrous tissue -- forms. Meanwhile, the internal carotid artery, which leads to the brain, decreases by as much as 16 percent when people have atherosclerotic plaque in their blood. The artery wall also grows an average of 14 percent thicker, the researchers found. The findings came from MRIs of 191 men a...Why African-Americans are at greater risk of hypertension and kidney disease
...th body mass index (BMI) -- indicator of body fatness compared to height -- and metabolic syndrome -- a group of abnormalities that is associated with atherosclerotic vascular disease and diabetes. "Future clinical studies must be done so we may fully understand the specific role of TGF-1 in how the kidne...Patients with moderate to severe periodontitis need evaluation for heart disease risk
...ion and possible treatment to reduce their risk of atherosclerotic cardiovascular disease (CVD), according to a speci...people with periodontitis are at increased risk of atherosclerotic CVD the accumulation of lipid products within the...explanation for the link between periodontitis and atherosclerotic CVD is not yet clear, but a leading candidate is i...Heart Damage After Vascular Surgery Raises Death Risks
...eople who showed no symptoms and 71 who had symptoms, according to the researchers. "Patients undergoing major arterial vascular surgery because of atherosclerotic disease are at high-risk for cardiac complications in the perioperative period," Dr. Olaf Schouten of the Erasmus Medical Center of Rotterdam, the Net...Spherix Announces Positive Phase 2 Study Results
...ct of diets containing sucrose vs. D-tagatose in hypercholesterolemic mice. Obesity . 2009 Feb;17(2):269-75.). A novel finding in this study was that atherosclerotic lesions detected in TAG-fed mice were composed of increased collagen, indicative of a more stable plaque phenotype. The results suggest that, in addi...CRESTOR(R) Reduced CV Risk in Patients Achieving Low LDL and hsCRP Targets in New JUPITER Analysis
...story of premature coronary heart disease (CHD) or smoking. hsCRP is a recognized marker of inflammation which is associated with an increased risk of atherosclerotic cardiovascular events. JUPITER is a part of AstraZeneca's extensive GALAXY clinical trials program, designed to address important unanswered qu...CRESTOR(R) Reduced Risk of Blood Clots in the Veins
...story of premature coronary heart disease (CHD) or smoking. hsCRP is a recognized marker of inflammation which is associated with an increased risk of atherosclerotic cardiovascular events. JUPITER is a part of AstraZeneca's extensive GALAXY clinical trials program, designed to address important unanswered qu...CRESTOR Demonstrates Dramatic CV Risk Reduction in a Large Statin Outcomes Study
...story of premature coronary heart disease (CHD) or smoking. hsCRP is a recognized marker of inflammation which is associated with an increased risk of atherosclerotic cardiovascular events. JUPITER is a part of AstraZeneca's extensive GALAXY clinical trials program, designed to address important unanswered questio...Following the dietary guidelines may slow heart disease in women
.... The study authors found that adherence to recommendations for whole-grain, total fat, and cholesterol intake were most associated with decreased atherosclerotic progression. The most important findings are that adherence to the DGA in individuals with atherosclerosis beneficially affects cardiovascular diseas...Promising 3-year data: Saving limbs with drug-eluting stents
...by restenosis (the re-narrowing of the artery at the site of angioplasty or stenting), the need for repeat treatments and the continued progression of atherosclerotic disease, leading to tissue death (gangrene) and amputation. Interventional radiologists have been studying a potential solutionthe use of drug-eluting...Simple test helps predict heart attack risk
...nown history of heart disease, stroke, diabetes or atherosclerotic vascular diseasealong with available data on stand...nown history of heart disease, stroke, diabetes or atherosclerotic vascular disease," said Murphy. "There is also a g...h actually detects subclinical already-established atherosclerotic disease, may actually perform better in terms of r...International study identifies gene variants associated with early heart attack
...risk were identified for the first time; and one of the novel regions also had been found, in a separate study by O'Donnell, to promote the buildup of atherosclerotic plaque in the coronary arteries. To analyze the effect of inheriting several risk-associated SNPs, participants were assigned a genotype score, which...Inflammation worsens danger due to atherosclerosis
...activation leads to reduced collagen maturation in atherosclerotic plaques of ApoE-deficient- mice," appears in the F...esterol diets, smoking, and diabetes. People with atherosclerotic plaques often show no symptoms for decades. atherosclerotic plaques consist of lipid cores covered by collagen...JCI online early table of contents: Jan. 19, 2009
...s atherothrombosis, where a blood clot (otherwise known as a thrombus) forms in a blood vessel supplying the heart at the site of a ruptured or eroded atherosclerotic plaque (the entity that causes hardening or furring of the arteries). Platelets have a key role in the development of these blood clots, and the devel...Friend or foe? How the body's clot-busting system speeds up atherosclerosis
...ndings. Specifically, they wondered whether the high level of urokinase in atherosclerotic artery walls was contributing to atherosclerosis or was evidence of the bod...-type plasminogen activator produced by macrophages speeds up the growth of atherosclerotic plaques and promotes dilation of the root of the aorta, one of the heart's ...Study supports reason for concern in childhood and adolescent obesity
...thelium (a single cell layer that lines all blood vessels) is key to maintaining vascular health. Endothelial dysfunction is a primary contributor to atherosclerotic cardiovascular disease (the buildup of fatty deposits on the inside walls of arteries) in adults and is associated with increased risk of heart attack...Genetic variants of USF1 are associated with the increased risk for cardiovascular disease
...1 effects and the pathophysiological state of an individual. To address the question if carriership of this risk allele has a direct impact on the atherosclerotic lesions of the coronary arteries and abdominal aorta, Kristansson used two study samples of middle-aged men with detailed measurements of atherosclero...Lipoic acid could reduce atherosclerosis, weight gain
...e study found that lipoic acid supplements reduced atherosclerotic lesion formation in two types of mice that are wid... useful adjunct in the prevention and treatment of atherosclerotic vascular diseases. We are excited about these r...file is similar, as well as the composition of the atherosclerotic lesions. These mouse models are routinely used in ...VIA Pharmaceuticals' DGAT1 Inhibitors Featured in American Diabetes Association Poster Presentation
... and implementing cardiovascular clinical trials using histological examinations, measurement of biomarkers, medical imaging and atherosclerotic plaque bioassays; -- the results of our clinical trials, including without limitation, with respect to the safety and efficacy of V...Atherotech Receives Patent for ApoB Measurement
...particularly valuable in hypertriglyceridemic and insulin-resistant states where LDL levels would be falsely reassuring and not representative of true atherosclerotic particle burden. "ApoB is much more predictive of risk than LDL," noted Michael Cobble, M.D., director of Canyons Medical Center in Sandy, Utah. ...VIA Pharmaceuticals Receives Anticipated Notice From NASDAQ
... and implementing cardiovascular clinical trials using histological examinations, measurement of biomarkers, medical imaging and atherosclerotic plaque bioassays; -- the results of our clinical trials, including without limitation, with respect to the safety and efficacy of V...VIA Pharmaceuticals Complies With NASDAQ Rules
...plexities in designing and implementing cardiovascular clinical trials using histological examinations, measurement of biomarkers, medical imaging and atherosclerotic plaque bioassays; the results of our clinical trials, including without limitation, with respect to the safety and efficacy of VIA-2291; ...VIA Pharmaceuticals Secures Financing Up to $10.0 Million
...plexities in designing and implementing cardiovascular clinical trials using histological examinations, measurement of biomarkers, medical imaging and atherosclerotic plaque bioassays; the results of our clinical trials, including without limitation, with respect to the safety and efficacy of VIA-2291; ...9(S)-HODE-d4, Deuterium Conjugated/Tagged from Cayman Chemical
Description:...-HODE by GC- or LC-mass spectrometry. 9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals. It has been detected in atherosclerotic plaques, as an esterified component of membrane phospholipids and in oxidized LDL particles....9(S)-HODE-d4, Deuterium Conjugated/Tagged from Cayman Chemical
Description:...-HODE by GC- or LC-mass spectrometry. 9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals. It has been detected in atherosclerotic plaques, as an esterified component of membrane phospholipids and in oxidized LDL particles....