Atherosclerosis

Potential atherosclerosis drug exhibits no harmful side-effects in liver

Researchers have developed and tested a synthetic atherosclerosis drug that can reduce the build-up of dangerous blood vessel plaques without producing the side-effect of fatty liver disease (which leads to its own set of problems like diabetes). The encouraging results of this study in mice could...

Prostaglandin receptor key to atherosclerosis development

Atherosclerosis a disease that includes the buildup of fatty, cholesterol-laden lumps of cells inside the artery wall is the underlying cause of heart attacks and strokes. A team of Vanderbilt University Medical Center investigators has now demonstrated that a receptor for prostaglandin-E2 pla...

Cholesterol, blood pressure control may reverse atherosclerosis in adults with diabetes

Aggressively lowering cholesterol and blood pressure levels below current targets in adults with type 2 diabetes may help to prevent and possibly reverse hardening of the arteries, according to new research supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Instit...

Avandia May Slow Atherosclerosis After Bypass Surgery

But this new study of diabetes drug doesn't prove it's safe, critics say TUESDAY, April 1 (HealthDay News) -- The controversial diabetes drug Avandia appears to slow the progression of atherosclerosis in diabetic patients who have undergone cardiac bypass surgery, thus protecting them ...

Genes that protect against atherosclerosis identified

One way of combating atherosclerosis is to reduce levels of bad cholesterol in the blood. Scientists at the Swedish medical university Karolinska Institutet have now identified the genes that bring about this beneficial effect. In a new study on mice, which is presented in the open-access jo...

CRESTOR(R) Now Indicated to Slow the Progression of Atherosclerosis in Patients With Elevated Cholesterol

WILMINGTON, Del., Nov. 9 /PRNewswire-FirstCall/ -- AstraZeneca (NYSE: AZN) announced today that the U.S. Food and Drug Administration (FDA) has approved CRESTOR(R) (rosuvastatin calcium) as an adjunct to diet to slow the progression of atherosclerosis in patients with elevated cholesterol. Thi...

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Atherosclerosis in Medical Technology

TWO NEW KLRI PEER-REVIEWED PUBLICATIONS: Hormone Therapy May Reduce Atherosclerosis in Women Close to Menopause; Growth Hormone May Increase Risk of Diabetes, Improve Lipid Profile in Men

PHOENIX, Aug. 3 /PRNewswire-USNewswire/ -- The Phoenix-based Kronos Longevity Research Institute (KLRI) has published two new publications on hormone therapies and their effects on reducing the risks of cardiovascular disease in older adults. Cardiovascular disease caused by ...

New Analysis of METEOR Study Demonstrate Effects of AstraZeneca's CRESTOR(R) (Rosuvastatin Calcium) on Atherosclerosis in Patients With Two or More Risk Factors for Cardiovascular Disease

ORLANDO, Fla., Nov. 7 /PRNewswire-FirstCall/ -- A new analysis presented today from METEOR (Measuring Effects on intima media Thickness: an Evaluation Of Rosuvastatin) showed CRESTOR(R) (rosuvastatin calcium) 40 mg slowed the progression of carotid intima-media thickness (CIMT) in four patient...

VAP Cholesterol Test Helps Reveal Association Between Adiponectin Levels and Atherosclerosis

Detailed lipid profile helps clinicians identify risk in patients, including non-diabetics, despite normal LDL levels and statin therapy BIRMINGHAM, Ala., July 21 /PRNewswire/ -- Using the VAP Cholesterol Test from Atherotech, researchers have identified a link between adiponectin and he...

Isis Reports Reduction of apoB-100 Levels in a Murine Model Resulting in Up to 92% Reduction of Atherosclerosis

CARLSBAD, Calif., April 18 /PRNewswire-FirstCall/ -- Isis Pharmaceuticals, Inc. (Nasdaq: ISIS ) presented the results of two studies designed to assess the impact of lowering apoB-100 on atherosclerosis at the 2008 Annual Atherosclerosis, Thrombosis and Vascular Biology (ATVB) Conference in A...

VIA Pharmaceuticals Presents Data at American Heart Association Meeting Showing VIA-2291 Significantly Reduces Inflammation in Preclinical Model of Atherosclerosis

SAN FRANCISCO and ORLANDO, Fla., Nov. 6 /PRNewswire-FirstCall/ -- VIA Pharmaceuticals (Nasdaq: VIAP ), a biotechnology company focused on the development of compounds for the treatment of cardiovascular disease, today presented data showing that VIA-2291 significantly inhibited vascular infla...

First Study To Show Positive Benefit On Atherosclerosis For People With Early Signs Of Diseased Arteries

METEOR Trial Shows CRESTOR Slowed Progression Of Atherosclerosis In People At Low-Risk* Of Coronary Heart Disease LONDON, March 26, 2006-AstraZeneca today announced that the METEOR clinical trial of CRESTOR is the first study to show a positive effect on atherosclerosis in people with early sign...

Atherosclerosis in Medical Products

RX ACCULINK Carotid Stent System

Description:... The RX ACCULINK Carotid Stent System is designed to provide easy and accurate stent placement in patients who have carotid atherosclerosis and are at high risk for conventional surgery. The 0.014 guide wire compatible RX ACCULINK Carotid Stent System is 6F sheath/8F guide catheter compat...
Company:Abbott Vascular

CRP, Ultra-Sensitive ELISA Test

Description:...ariety of conditions such as, myocardial infarction, bacterial infection, rheumatoid arthritis, inflammatory bowel disease, acute appendicitis [3] and atherosclerosis [4]. Additionally, CRP levels have recently been found to be a predictive factor for cardiovascular events [5, 6] and peripheral vascular disease [4]....
Company:Diagnostic Systems Laboratories, Inc.

Atherosclerosis in Medical Definition

Arterial stiffness

...ce January 2007 . Arteries stiffen as a consequence of age and atherosclerosis . The two leading causes of death in the developed world, myocardial infarction and stroke , are both a direct consequence of atherosclerosis and increased arterial stiffness is associated with an increased risk of ca...

Pathology

... heart conditions Heart failure - Cardiomegaly - Ventricular hypertrophy ( Left , Right ) Arteries , arterioles and capillaries atherosclerosis - Aortic dissection - Raynaud's phenomenon / Raynaud's disease - Buerger's disease - Intermittent claudication Veins , lymphatic vess...

Atherosclerosis in Medical Dictionary

Atherosclerosis

Atherosclerosis is the condition in which an artery wall thickens as the result of a build-up of fatty materials such as cholesterol. It is a syndrome affecting arterial blood vessels, a chronic inflammatory response in the... A patient's guide to atherosclerosis or arteriosclerosis...

Unstable angina

... heart muscle, generally due to obstruction or spasm of the coronary arteries . Coronary artery disease, the main cause of angina , is due to atherosclerosis of the cardiac arteries.... Unstable angina is a condition in which your heart doesn't get enough blood flow ... During an unstable ...

Smooth muscle

...iry" look of primarily filaments in the cytoplasm. ... Smooth muscle . ... Smooth muscle proliferation and differentiation. Mechanism of atherosclerosis ... Anti- smooth muscle -actin antibody (clone 1A4) was ... Smooth Muscle ... Smooth muscle has no striations and is composed of sma...

Renal artery stenosis

... Renal artery stenosis is the narrowing of the renal artery , most often caused by atherosclerosis or fibromuscular dysplasia. This narrowing of the renal artery can impede blood flow to the target kidney. Hypertension and... Explains the...

Heart Diseases

.... Heart ... Learn about heart attack and heart disease prevention through lifestyle changes, ... What are the risk factors for coronary atherosclerosis and heart disease ? ... heart disease n. A structural or functional abnormality of the heart , or of the blood vessels supplying the h...

Heart Disease

.... Heart ... Learn about heart attack and heart disease prevention through lifestyle changes, ... What are the risk factors for coronary atherosclerosis and heart disease ? ... The starting place for exploring information on heart disease and cardiology. ... is certainly a risk factor for ...

Atherosclerosis in Biological News

Inflammation worsens danger due to atherosclerosis

Stockholm, Sweden Current research suggests that inflammation increases the risk of plaque rupture in atherosclerosis. The related report by Ovchinnikova et al, "T cell activation leads to reduced collagen maturation in atherosclerotic plaques of ApoE-deficient- mice," appears in the February 20...

Friend or foe? How the body's clot-busting system speeds up atherosclerosis

Sometimes it's hard to tell friends from foes, biologically speaking. Naturally produced in the body, urokinase plasminogen activator and plasminogen interact to break up blood clots and recruit clean-up cells to clear away debris related to inflammation. In fact, urokinase manufactured as a drug ...

Aspirin and atherosclerosis

Aspirin has become one of the most widely used medications in the world, owing to its ability to reduce pain, fevers, inflammation, and blood clotting. In animal studies, aspirin has also been shown to prevent atherosclerosis, though none of its known mechanisms of action would seem to account for...

Failure to bridle inflammation spurs atherosclerosis

When a person develops a sore or a boil, it erupts, drawing to it immune system cells that fight the infection. Then it resolves and flattens into the skin, often leaving behind a mark or a scar. A similar scenario plays out in the blood vessels. However, when there is a defect in the resolutio...

Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism

A new study conducted by researchers from the University of Verona and the Institute G. Gaslini in Genova, Italy, confirms the pivotal role played by Cytomegalovirus infection in the pathogenesis of atherosclerosis. Atherosclerosis is the main cause of morbidity and mortality worldwide. Classic ...

In mice, drug protects against diabetes and atherosclerosis

Blocking a single protein with an experimental drug prevented and treated both type 2 diabetes and atherosclerosis in laboratory mice that had been fed unhealthy diets and were genetically predisposed to these common killers, according to an article published online at Nature on June 6, 2007. The ...

Atherosclerosis in Biological Technology

AFFiRiS AG: Atherosclerosis Vaccine Development Receives EU Support

VIENNA, Austria, May 27 /PRNewswire/ -- The atherosclerosis vaccine development program by AFFiRiS AG is receiving financial support from the EU's EUROTRANS-BIO call. The respective project is being carried out in cooperation with German company EMC microcollections GmbH. The aim of atheroscle...

Research Published in Nature Medicine Shows Disruption of Chemokine Interactions Inhibits Atherosclerosis in Mice

San Diego-Based Carolus Therapeutics Focuses on Discovery and Development of Anti-Inflammatory Drugs Based on Collaborators' Findings at RWTH Aachen University in Germany SAN DIEGO, Jan. 5 /PRNewswire/ -- Research published in Nature Medicine shows that the disruption of the interactions be...

Interleukin Genetics to Present New Findings at the 11th Cardiovascular Genomics and Atherosclerosis Symposium

Genetic Variations Identify Predisposition to Early Cardiovascular Events in Asian Populations WALTHAM, Mass., Oct. 30 /PRNewswire-FirstCall/ -- Interleukin Genetics, Inc. (Amex: ILI ), announced today that Kenneth Kornman, Ph.D., the company's Chief Scientific Officer, will present new res...

Old and new therapies combine to tackle atherosclerosis

Futuristic nanotechnology has been teamed with a decades-old drug to beat atherosclerotic plaques in research conducted at Washington University School of Medicine in St. Louis. The scientists have found that drug-laced nanoparticles plus a statin could stop the growth of tiny blood vessels that...

VIA Pharmaceuticals Receives Anticipated Notice From NASDAQ

...'s lead candidate, VIA-2291, targets a significant unmet medical need: reducing inflammation in the blood vessel wall, which is an underlying cause of atherosclerosis and its complications, including heart attack and stroke. In addition, VIA's pipeline of drug candidates includes other compounds to address other un...

Santaris Pharma - Interim Report for the Period 1 January to 30 June 2009

...h. University, Denmark - European Association for the Study of the Liver, Copenhagen - AACR, Annual meeting. - 15th Annual Scandinavian atherosclerosis Conference - Meeting Medicon Valley arranged by Medicon Valley Alliance, Cph. - DxRx Summit, Boston, USA - Danish Biotech Annual Meetin...

Atherosclerosis in Biological Products

ChemiArray Mouse Lysate Atherosclerosis Antibody Array I, 20 cytokines per membrane from CHEMICON

Description: Request Info...
Company:CHEMICON

Human Atherosclerosis Antibody Array I Kit, ChemiArray, 20 cytokines per membrane from CHEMICON

Description: ChemiArray Human Cytokine Antibody Array VII, 60 cytokines per membrane...
Company:CHEMICON

Human Atherosclerosis Antibody Array 1.1 (4) Kit, RayBio from Raybiotech, Inc.

Description: RayBio Human Atherosclerosis Antibody Array 1.1 (4) with Accessory, detects 40 inflammatory factors (for lysate) Class: Antibody Array Products Product Group: Antibody Array...
Company:Raybiotech, Inc.

RayBio Mouse Atherosclerosis Antibody Array I & 1.1 Service from Raybiotech, Inc.

Description: Request Info...
Company:Raybiotech, Inc.

Atherosclerosis in Biological Dictionary

Vascular system

...roit, Michigan MI Region; Henry Ford, Vascular Surgery, Common Problems Associated with the Vascular System ; What is vascular disease? What is atherosclerosis ... The function of the vascular system is to nourish each cell in the body. ... Vascular System of the Spine. Keith Bridwell, MD. Orthop...

Renal arteries

...is directed across the crus of the diaphragm, so as to form... Renal artery stenosis is the narrowing of the renal artery, most often caused by atherosclerosis or fibromuscular dysplasia. This narrowing of the renal artery can impede blood flow to the target kidney. Hypertension and... More about Renal ...

Mutation

...es diversity ... A intermediate level expository answer to the question: Are mutations harmful? ... Appendix I - mutation rates. Appendix II - atherosclerosis resistance ... Looks at changes in the information stored in the genetic material, how they occur, and what the consequences of such changes are, a...

Monocytes

...body and there ... Developed by Baylor College of Medicine, Lipids Online provides up-to-date resources for researchers, faculty, and clinicians in atherosclerosis and other lipid ... Monocytes are formed from monoblasts. Collectively, lymphocytes and monocytes ... Monocytes deposit themselves in var...

Lipids

...oids, and waxes. Developed by Baylor College of Medicine, Lipids Online provides up-to-date resources for researchers, faculty, and clinicians in atherosclerosis and other lipid ... The packing of lipids within the bilayer also affects its mechanical properties, ... Lipids self-assemble into this struc...

Coronary arteries

...blocked by ... Coronary Artery Disease (CAD) most often results from atherosclerosis which happens when a waxy substance forms inside the arteries that supply...olves the coronary arteries it ... Coronary arteries suffering from atherosclerosis lose the ability to release the ... ...