Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
For patients with high-risk breast cancer treated with radical mastectomy and adjuvant chemotherapy, the addition of radiation therapy leads to better survival outcomes with few long-term toxic effects, according to a 20-year follow-up of a randomized trial, which appears in the January 19 issue of the Journal of the National Cancer Institute. The British Columbia randomized radiation the...Asthma gene clusters identified
Children who suffer from acute asthma attacks share a genetic profile that appears to be unique to these children, according to a new study by researchers at Cincinnati Children's Hospital Medical Center. The discovery opens the door to the possibility of designing treatments specifically tailored to children who suffer from the severest forms of asthma. The findings appear in the Feb. 10...Researchers Discover Gene That Determines Asthma Susceptibility By Regulating Inflammation
Disruption of a single gene, Nrf2, plays a critical role in determining the susceptibility to asthma. A research team led by Shyam Biswal, PhD, at the Johns Hopkins Bloomberg School of Public Health found the absence of Nrf2 exacerbated allergen-mediated asthma in mice models. The study’s findings, published in the July 4, 2005, edition of the Journal of Experimental Medicine, may hold therapeuti...Bacteria in Household Dust May Trigger Asthma Symptoms
New research shows that bacteria lurking in household dust produce chemicals that may trigger asthma and asthma-related symptoms such as wheezing. These bacterial chemicals, called endotoxins, particularly those found on bedroom floors, were linked with increased respiratory problems in adults. This study, supported by the National Institute of Environmental Health Sciences (NIEHS), a part of the...How 'Dirt' Could Educate The Immune System And Help Treat Asthma
An Earth System model developed by researchers at the University of Illinois at Urbana-Champaign indicates that the best location to store carbon dioxide in the deep ocean will change with climate change. The direct injection of carbon dioxide deep into the ocean has been suggested as one method to help control rising carbon dioxide levels in the atmosphere and mitigate the effects of glob...High-throughput gene expression analysis to screen for anti-asthma drugs
Andreas Pahl, Uwe Oelmller,* and Susanne Ullmann Department of Pharmacology, University of Erlangen, Erlangen, Germany * QIAGEN GmbH, Hilden Germany Drug library screening based on gene expression analysis requires reliable and reproducible methods of RNA pu...Asthma may actually be prevented by Dust and Dirt
National Jewish Medical and Research Center researchers in USA say that a little dust and dirt in the home may help prevent asthma later in life. Environmental endotoxin may have an allergy-protective effect in some infants whose homes have high levels of the bacteria by-product. "Endotoxin seems to drive the immune system to produce cytokines that inhibit certain processes in the body that may...Inhaled Steroids Safe & Effective for Children with Asthma
A 5-year, 8-center study by "Childhood Asthma Management Program" (CAMP) has indicated that inhaled steroids are safe and effective for the long-term treatment of children with mild to moderate asthma. "Although asthma experts around the world have recognized the effectiveness of inhaled corticosteroids in treating asthma, their long term effects in children were not clear, and questions have bee...What happens when Asthmatics consume Aspirin?
One of the commonest and most troublesome disease affecting millions world wide is asthma. Asthmatics not only suffer from the usual symptoms of the disease but they are unfortunate in more ways than one. It is common knowledge that asthmatics are warned to stay away from aspirin and other non-steroidal anti-inflammatory drugs. What happens when they take aspirin? And further more if consuming as...Fireworks can spell death for asthmatic children
With many festivals round the corner its boom time for fireworks. We can never imagine diwali without fireworks. Pongal or karthigai also have their share of fireworks. Then of course the usual rigmarole of India – Pakistan cricket matches where even cricket stadia aren’t exempted from fireworks. Last but not the least, private functions like marriages, birthdays and other occasions call for a cl...AsthmaKit™ Methacholine Bronchoprovocation Test Kit
Description:This convenient, procedural kit contains everything the health care professional needs to perform the methacholine challenge test quickly and efficiently: 7 nebulizers, T-piece and mouthpiece, exhalation filter, gas supply tubing, syringe and needle. Shipped 5 kits per case. Not available in the European Community. Intended Use: AsthmaKit is a procedural kit providing t...Mild Asthma, a Revolutionary Therapy from Italian Research
Published by the New England Journal of Medicine the B.E.S.Tstudy conducted in Italy “TAKEN ONLY WHEN NEEDED AND THE DISEASE CAN BE CONTROLLEDSUCCESSFULLY” Prof. Fabbri: “Daily drug useless for mild persistenttypes affecting over one million 200 thousand people”.Chiesi’s commitment to pneumological research MILAN, Italy, 29th May 2007 &nda...New Survey Finds Troubling Data on American Asthma Sufferers
Disconnect Between Patient Perception and Symptom Severity; NewResources for Patients, Parents WASHINGTON, May 15, 2007 /PRNewswire-USNewswire/ -- A new surveyreleased today by the National Consumers League shows that Americanasthma sufferers are not exactly breathing easy these days. Four inten asthma sufferers understand asthma medication categoriessomewhat or not at all, and the more r...