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Assayed in Medical News

Teenage stress has implications for adult health

...family and friends, peer harassment or any kind of punishment by parents or teachers. Blood samples were obtained an average of eight months later and assayed for circulating levels of the CRP protein; the research protocol took into account such factors as socioeconomic status, major stressful life events a...

New genomic test can personalize breast cancer treatment

... researchers are now investigating how each tumor type responds to these drugs to help determine the best treatment for each. Their 50-gene set can be assayed in preserved tumor samples left over from standard diagnostic procedures, so the group plans to study tumor samples from breast cancer cases going bac...

Also in the Nov. 11 JNCI

... in Houston and colleagues engineered human ovarian cancer cells to overexpress each of the receptors or to prohibit their expression. The researchers assayed cell behavior in vitro and by injecting them into mice. Ovarian cancer cells that expressed the LPA receptors gave rise to larger tumors and produc...

Multiple Independent Studies Report on Use of Cylex's Immune Cell Function Assay in Postoperative Monitoring of Kidney, Liver, and Heart Transplant Recipients

...pression: Protocols for Sensitized and ABO Incompatible Renal Transplantation: A Period of Consolidation) CMI was one of three parameters assayed in monitoring the responses of renal transplant patients to two different induction agents in this study from Johns Hopkins University School ...

Biomarkers predict risk for invasive breast cancer years before the tumor develops

... The combination of stress-activation and deregulation of p16/Rb signaling may represent a defining signature of basal-like carcinogenesis that can be assayed far in advance to the development of invasive disease and present clinical opportunities for appropriate aggressive intervention, concludes Dr. Tlsty....

A fresh look at existing therapies: Researchers explore ways to teach approved drugs new tricks

...eva activity is in pancreatic cancer, Jimeno says. The team used a tool known as gene set enrichment analysis (GSEA), which classifies 25,000 genes assayed in a chip into 198 predetermined pathways, be they metabolic, structural, or signal transduction. This analysis was conducted by Aik Choon Tan, Ph.D.,...

NIH awards Phylonix phase II SBIR to develop zebrafish models for eye diseases

...antages: 1) short assay time, 2) single dosing, 3) small amount of drug required for each test, 4) statistically significant numbers of animals can be assayed for each condition, 5) embryos maintenance during drug delivery is easy, and 6) low cost the estimated cost of each zebrafish assay is less than $100...

Novagali Pharma Presents Phase III Clinical Trial of Vekacia(R) for Vernal Keratoconjunctivitis

... The tested formulations were rated as comfortable by 94.4% (vehicle), 79.5% (Vekacia(R) 0.05%) and 80.6% (Vekacia(R) 0.1%). Blood levels of CsA were assayed after one month of treatment in 16 patients treated with Vekacia(R) and five patients had detectable CsA levels below 0.33ng/ml, a value which is cons...

A Novel Technique That Detects "Cancer Genes" From The Breath Of Smokers

... - that's what breathalyzers do when they measure small volatile molecules such as alcohol, as well as inflammation molecules that are currently being assayed to test the activity of asthma and other lung diseases," said Spivack. "But what is rather remarkable here is that DNA can be tested in the air that c...

Indicators of Dementia Found In Blood

... Dementia risk can be assayed by determining the levels of two proteins in the blood of the patient. The two proteins play an important role in determining the risk of dementia in ...
Assayed in Medical Technology

Genes Identified That Enhance Tumor Cell Sensitivity to CTI's Cancer Drug Brostallicin

...ected ovarian cancer cell lines. RNA interference is a cellular process that results in the targeted knockdown of specific genes. The current screen assayed the effect of over 7,000 individual gene knockdowns, representing the "druggable" genome, on brostallicin response. The identified genes, represe...

Sangamo BioSciences Announces Presentation of Phase 1b ZFP Therapeutic Data at American Diabetes Association Meeting

...gets the major peripheral nerves in the legs and feet. Peripheral blood samples taken before and at various times post-treatment with SB-509 will be assayed and the numbers of circulating stem cells will be assessed using stem cell-specific enzymatic activity (aldehyde dehydrogenase staining), culture-base...

Study Shows Plasma-Derived Human Thrombin Equivalent to Bovine Thrombin in Achieving Hemostasis in Surgery

...imilar adverse event profiles. However, more patients who received bovine thrombin demonstrated seroconversion for at least one of the four antibodies assayed than did patients who received human thrombin (12.7% versus 3.3%, respectively). Results from a separate second study were also presented at the SABM...

Novagali Pharma Presents at AACO the Results of its Pivotal Phase III Clinical Trial of Vekacia in Children Suffering From Vernal Keratoconjunctivitis

.... The tested formulations were rated as comfortable by 94.4% (vehicle), 79.5% (Vekacia(R) 0.05%) and 80.6% (Vekacia(R) 0.1%). Blood levels of CsA were assayed after one month of treatment in 16 patients treated with Vekacia(R) and five patients had detectable CsA levels below 0.33ng/ml, a value which is cons...
Assayed in Medical Products

Urine Assayed Control Level 2

Description: Human based material available in two levels for the control of accuracy and precision for upto 23 analytes....
Company:Randox Laboratories Ltd.

Urine Assayed Control Level 3

Description: Human based material available in two levels for the control of accuracy and precision for upto 23 analytes....
Company:Randox Laboratories Ltd.

Lyphochek Assayed Chemistry Control

Description: Lyphochek Assayed Chemistry Control requires no special diluent and has good reconstituted stability for enzymes and CO2. It is assayed for most major instruments and methodologies....
Company:Bio-Rad Laboratories

Liquid Assayed and Unassayed Multiqual Controls

Description: Liquid Assayed and Unassayed Multiqual Controls are comprehensive, liquid, human serum based chemistry controls, available in three levels....
Company:Bio-Rad Laboratories

Hemoglobin Control for Hemocue Analyzers

Description:... QC HGB is an assayed quality control material for Hemocue analyzers. This control is a solution of stabilized human red cells and is available in 3 levels for monitoring a...
Company:RNA Medical

QC 253 Full Range CO-Oximeter Control

Description:... QC 253 is an assayed quality control material used for monitoring the measurements of total hemoglobin and hemoglobin fractions on CO-Oximeter instrumentation. It provides...
Company:RNA Medical

QC 900 Hematocrit Control

Description:... QC 900 is an assayed quality control material for analyzers measuring hematocrit by electrical conductivity methodologies. It is available in two (2) levels for monitoring...
Company:RNA Medical

CVC 123 Calibration Verification Controls

Description:... CVC 123 is an assayed quality control material used for confirming the calibration and linearity of blood gas, electrolyte, and metabolite instrumentation....
Company:RNA Medical

CVC 223 CO-Oximeter Calibration Verification Controls

Description:... CVC 223 is an assayed quality control material used for confirming the calibration and linearity of CO-Oximeter instrumentation....
Company:RNA Medical

QC 233 CO-Oximeter Control

Description:... QC 233 is an assayed quality control material used for monitoring the measurements of total hemoglobin and hemoglobin fractions on CO-Oximeter instrumentation. It is avail...
Company:RNA Medical

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Assayed in Medical Dictionary

Fibrinogen

...ot as important as the big risk factors ... Birth weight was inversely associated with fibrinogen (β per 1-unit change in z ... Fibrinogen was assayed by the automated von Clauss assay, and factors VII and ... Excessive fibrinogen use (as in disseminated intravascular coagulation) Fibrinolysis ...
Assayed in Biological News

Tiny samples could yield big predictive markers for pancreatic cancer

...technique, Tokar and his colleagues collected fluid from the cysts of 20 research participants with a small needle. Yeung and his laboratory team then assayed the fluid to determine the number and type of proteins it contained. Identifying the proteins took more than eight months of continuous time with a ma...

CO2 drop and global cooling caused Antarctic glacier to form

...ific organic molecules from ancient plankton that only lived at certain temperatures and were later preserved in ocean sediments. These molecules were assayed in ocean cores collected by the Integrated Ocean Drilling Program (IODP) and earlier marine programs that study Earth history by coring deep-ocean sed...

Caltech scientists develop 'barcode chip' for cheap, fast blood tests

...moved from a patient's arm and taken to a laboratory, where the blood is centrifuged to separate whole blood cells from the plasma. The plasma is then assayed for specific proteins. "The process is labor intensive, and even if the person doing the testing hurries, the tests will still take a few hours to com...

Caltech researchers find dual-use sexual attraction and population-control chemicals in nematodes

...h scholar at Caltech, Sternberg, and his colleagues at the University of Florida, the United States Department of Agriculture, and Cornell University, assayed and analyzed worm sweat and found that it consisted of a blend of three related chemicals, called ascarosides. The chemicals looked suspiciously like ...

Hearts of male and female rainbow trout are different

...actile performance (resting tension, twitch force, post-rest potentiation and other variables. Frozen samples of ventricle tissue were homogenized and assayed for citrate concentration. Ventricle rings were processed, sectioned and stained. Light microscopy was used to capture images of ventricle layers and ...

Novel method reveals how menthol discovery could point towards new or improved pain therapies

...t will be published in the journal's April edition (Vol. 9, No. 4). Utilizing a novel mutagenesis and high-throughput screening approach, the study assayed 14,000 TRPM8 mutants to find mutants that were not enhanced by menthol but were otherwise functioning normally. The scientists' analysis pinpointed a...

Bacteria in Household Dust May Trigger Asthma Symptoms

...dardized protocol to collect samples. Dust samples were collected from bedroom, kitchen and living room floors, bedding, and upholstered furniture and assayed for endotoxin. A disease association analysis was performed to correlate endotoxin concentrations to specific health outcomes. “When we analyzed th...
Assayed in Biological Technology

Morria Biopharmaceuticals Plc Announces Results From its Pre-Clinical Screening of Novel Anti-Inflammatory Compounds

...ds clearly modulate them efficiently," said Yuval Cohen, President of Morria Biopharmaceuticals. Specifically, several of the inflammatory mediators assayed have been identified as important players in Morria's current clinical programs (allergic rhinitis and dermatitis) and pre-clinical programs (asthma, ...

Quantitation of Acrylamide in Food Samples on the Finnigan TSQ Quantum Discovery by LC/APCI-MS/MS

...or this standard is 0.99 ng/mL, equating to a relative error of -1.0%. Table 2 reports the results for four different food samples that were assayed for acrylamide using the column-switching LC method and MS/MS detection. The acrylamide concentrations in each food sample were calculated by multiply...

Receptor Binding Assays using Fluorescence Polarization Detection: the [FP]2TM Characterized Tracers

...-TMR, colored compound interference and autofluorescence from cell membrane fragments can be minimized 7-9 . Furthermore, nM binding affinities can be assayed with satisfactory accuracy and precision 10 . The only insurmountable limitation to FP with the current level of HTS reader sensitivity, ava...

Evaluation of FlashPlate in a Helicase Assay

...with 200 μl of 50 mM Tris (pH 7.5), 50 mM NaCl at 37C. Each well contained approximately 10,000 to 12,000 CPM. 4. The coated plate was assayed with various amounts of SV40 Large T-Antigen (0 μg, 0.7 μg, 1.4 μg, 2.8 μg) in 50 μl of assay buffer, in the presence or abse...

A highly sensitive ATP-luminescence assay using VICTOR2 with the dispenser option

...iferation, cytotoxicity and cell adhesion studies. One application is the detection of microbial contamination in milk. In this study ATP samples were assayed with a Boehringer Mannheim flash type kit using VICTOR 2 dispenser option. The detection is based on a light emitting (560 nm) reaction of ATP and lu...

Coated Plate Immunoassay on the MicroBeta - eg. TSH - IRMA

...d analyze the data with MultiCalc. As a comparison two other commercially available plates (Labsystems-Polysorp and Nunc-Maxisorp) were also assayed in parallel to the Wallac (1450-401) plate to show any observable differences in plate performance. RESULTS The graphs (Fig.1) ...

Counting Cytostar-T scintillating microplates on the MicroBeta JET

...he agonist through the injectors of the MicroBeta JET. Duplicate wells were assayed containing 50 μl [ 14 C] guanidinium (10 μCi/ml) to which was add...ynurenic acid was detrmined on the GluR6 assay system. Duplicate wells were assayed containing 50 μl [ 14 C] guanidinium and either 0.1 μM domoate or...

Multiplexed Quantitative Peptide Assays for Protein Biomarkers of Cardiovascular Disease in Human Plasma

...ple, splitting it in two and performing parallel depletions, followed by a further split of each to perform parallel digestions. All samples were then assayed and correlated (Figure 5, left). Initial results suggest that these types of sample preparation techniques can be performed in a highly reproducible m...

A Mix-and-Read Cell-Based Assay for Hybridoma Screening Using the FMAT 8100 HTS System

...identified 6 positive wells from one plate of the screen (Figure 3, panel A). However, only one positive well is evident from the same plate assayed with a cell ELISA (Figure 3, panel B). The remaining wells identified as positives by the FMAT system are obscured by the high fluorescent b...

Development of a sensitive enzyme fragment complementation assay for cyclic adenosine 3', 5' monophosphate and its validation for pharmacological screening at G protein-coupled receptors

...4-well autofluorescence/colored compound plates (a custom set prepared by The ChemBridge Corporation, San Diego, CA, USA), giving 6400 tests in total, assayed over 5 ×1536-well plates.

Method The source 384-well plates contained each compound nominally at a concent...

Assayed in Biological Products

SphingoStrips 10 pk from Echelon Biosciences Inc.

Description:... SphingoStripsTM contain fifteen different biologically active, nitrocellulose-immobilized lipids at 100 pmol per spot, which can be assayed for protein binding and specificity using a simple blot overlay experiment....
Company:Echelon Biosciences Inc.

Ligase, T4 DNA from USB Corp.

Description:...l (pH 7.6), 100mM NaCl, 1mM DTT, 0.5mM EDTA, 50% glycerol. Shipping and Storage: Shipped on dry ice. Store at -20C. Assay Conditions: T4 DNA Ligase is assayed according to the pyrophosphate exchange method of Weiss et al. The reaction mixture (300 l) contains 67mM Tris-HCl, (pH 7.8), 6.7mM MgCl 2 , 10mM DTT...
Company:USB Corp.

ProtoArray Yeast PPI Kit from Invitrogen

Description:...single day, instead of the several weeks required using alternatives such as yeast two-hybrid systems. In addition, protein interactions can be easily assayed under different conditions to better understand interaction dynamics. Using the Yeast ProtoArray PPI Kit, protein-protein interactions screening tak...
Company:Invitrogen

Canine Pancreatic Microsomal Membranes from Promega

Description:...e been isolated free from contaminating membrane fractions and stripped of endogenous membrane-bound ribosomes and mRNA (1). Membrane preparations are assayed for both signal peptidase and core glycosylation activities using two different control mRNAs. The two control mRNAs supplied with this system are the...
Company:Promega
Assayed in Biological Dictionary

Restriction enzymes

...ermentas restriction enzymes show optimum activity at temperatures other ... Restriction enzymes without recognition sites on lambda DNA are assayed with ... 1 Restriction Enzyme Definition. 2 Fragment complementarity and splicing ... Image:SmaI restriction enzyme recognition site.svg ...

Guard cell

... signaling pathways are illustrated as graphically linked models: ... A limitation of these techniques is that only a single guard cell can be assayed at one time. ... Guard cell vacuoles did not show bright fluorescence (Figure ... Guard cells regulate stomatal pore size to allow CO2 up...
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(Date:4/24/2014)... and stressful outcomes for parents who have a child ... says a recent study led by a researcher at ... numerous and life-changing and stress levels high, the vast ... reported positive outcomes as well, a phenomenon known as ... issue of the American Journal of Orthopsychiatry . ...
(Date:4/24/2014)... in the new Institute for Biomedical Sciences at ... million federal grant to develop novel therapeutics against ... from the Eunice Kennedy Shriver National Institute Of ... Institutes of Health will support Plemper,s drug development ... least one distinct alternative compound. , Infections by ...
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(Date:4/23/2014)... researchers say clinical trials for a new experimental ... very promising. Patients treated with CPX-351, a combination ... showing better responses than patients treated with the ... myeloid leukemia is an aggressive blood cancer with ... older patients," explained Jeffrey Lancet, M.D., senior member ...
Breaking Medicine News(10 mins):Health News:Parents of severely ill children see benefits as caregivers, says study 2Health News:Study: Altruistic adolescents less likely to become depressed 2Health News:Moffitt Cancer Center's phase 3 study may be game-changer for acute myeloid leukemia 2
(Date:4/24/2014)... pleased to announce that it has assumed ownership of ... University of Wisconsin. , The Journal of ... journal that publishes papers on all aspects of the ... molecular to the ecological -- as well as their ... individuals and institutions, and it provides a reasonably priced ...
(Date:4/24/2014)... improved with new insights into the make-up of tropical ... Amazon Basin have revealed unprecedented detail of the size, ... comparing satellite maps with hundreds of field plots. ... accurately the amount of carbon each tree can store. ... in which trees are given a cash value according ...
(Date:4/23/2014)... Africa,s Congo rainforest, the second-largest tropical rainforest in the ... the past decade. , The study, led by Liming ... York, shows between 2000 and 2012 the decline affected ... research, published Wednesday in Nature , is one ... effects of long-term drought on the Congo rainforest using ...
Breaking Biology News(10 mins):ESA to publish the Journal of Insect Science 2Amazon rainforest survey could improve carbon offset schemes 2NASA satellites show drought may take toll on Congo rainforest 2NASA satellites show drought may take toll on Congo rainforest 3
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