Aripiprazole

For Bipolar Depression, Surveyed Experts Indicate That Current and Emerging Therapies Have No Advantage Over Seroquel in Decreasing the Severity of Symptoms

...ipolar Depression: Despite Negative Results, Physicians Still Hopeful About aripiprazole also finds that an oral therapy that carries a lower risk of weight gain t...ipolar Depression: Despite Negative Results, Physicians Still Hopeful About aripiprazole is a DecisionBase 2009 report. DecisionBase 2009 is a decision-support too...

Otsuka America Pharmaceutical, Inc. Announces the Appointment of Mark Altmeyer as President and Chief Executive Officer

...for use in pediatric patients with depression (see Boxed WARNING). Contraindication : Patients should not use ABILIFY if they are allergic to aripiprazole or any of the ingredients in ABILIFY. Allergic reactions have ranged from rash, hives and itching to anaphylaxis, which may include difficulty breath...

Most Newer Antipsychotics No Better Than Older Ones, Just Different

...all to medium effect sizes." But, other second generation drugs, such as aripiprazole (Abilify), quetiapine (Seroquel), sertindole (Serdolect), ziprasidone (Geod...fective than first-generation drugs, the researchers reported. And, only aripiprazole and ziprasidone among the second-generation drugs did not induce more weigh...

Comparison of antipsychotic treatments in adolescents with schizophrenia

...e the treatment of children and adolescents with schizophrenia. Although the U.S. Food and Drug Administration (FDA) has recently approved the use of aripiprazole and risperidone for adolescents with schizophrenia, few controlled data are available to help guide clinicians regarding the management of children an...

Rates of bipolar diagnosis in youth rapidly climbing, treatment patterns similar to adults

...r an antipsychotic medication, although young patients were more likely to be prescribed one of the newer, atypical antipsychotic medications, such as aripiprazole (Abilify) or olanzapine (Zyprexa), than other types of antipsychotics. This finding suggests that doctors may be basing their treatment choices for bi...

US Lawmakers Considering Legislation to Restrict Payments by Drug Companies to Doctors

...pical antipsychotics are second-generation medicines designed to cause fewer neurological complications than conventional antipsychotics. They include aripiprazole (sold as Abilify), olanzapine (Zyprexa), quetiapine (Seroquel), risperidone (Risperdal), and ziprasidone (Geodon). Each is approved by the Food and Dr...

No Evidence to Support Many Off-label Uses of Atypical Antipsychotics

...ons than conventional antipsychotics. They include aripiprazole (sold as Abilify), olanzapine (Zyprexa), quetiapin...nalysis showed a small benefit for risperidone and aripiprazole in the treatment of agitation and psychosis. Anoth...atients with schizotypal personality disorder, and aripiprazole may help patients with borderline personality diso...

Aripiprazole in Medical Technology

Six-Week Investigational Study In Adults With Major Depressive Disorder Evaluates The Effectiveness of Adjunctive Aripiprazole Therapy With Antidepressants

...- In adults with major depressive disorder, adding aripiprazole to antidepressant therapy (ADT) resulted in signif...one of two completed studies evaluating adjunctive aripiprazole with ADT. "Investigational studies are important...plus double-blind adjunctive placebo or adjunctive aripiprazole (2-20 mg/day). The primary efficacy endpoint was...

Investigational Study Evaluates the Effectiveness of Aripiprazole in Adolescents With Schizophrenia

...ristol-Myers Squibb Company atypical antipsychotic aripiprazole demonstrated significant improvement compared to p... (n=100) or 30 mg/day (n=102)] or placebo (n=100). aripiprazole was started at 2 mg/day and titrated to the target...ercent of placebo-treated patients). Both doses of aripiprazole demonstrated improvement compared to placebo (p-va...

Aripiprazole in Biological Technology

Orexigen(R) Therapeutics Initiates First Clinical Trial of OREX-003 for the Mitigation of Antipsychotic-Associated Weight Gain

...which broadly covers zonisamide in combination with various marketed atypical antipsychotics including olanzapine, clozapine, risperidone, quetiapine, aripiprazole and ziprasidone through 2025. We believe that these patents complement each other and provide a strong patent portfolio for OREX-003. Orexigen has lic...

OREXIGEN(R) Therapeutics Receives Notice of Allowance for U.S. Patent Covering the Composition of Matter in OREX-003

.... If issued, this patent will also cover zonisamide in combination with other atypical antipsychotics, including clozapine, risperidone, quetiapine, aripiprazole and ziprasidone. Zonisamide is also a component of the Company's obesity treatment candidate Empatic(TM), which is in the later stages of Phase II cli...

U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) as the First Medication for Add-On Treatment of Major Depressive Disorder (MDD)

...ty survey replication (NCS-R). JAMA. June 18 2003;289(23):3095-3105. (3) Berman RM, Marcus RN, Swanink R, et al. The Efficacy and Safety of aripiprazole as Adjunctive Therapy in Major Depressive Disorder: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study. J Clin Psychiatry. 20...