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Arginine in Medical News

Astellas Launches Vaprisol(R) (Conivaptan Hydrochloride Injection) Premixed in 5% Dextrose for the Treatment of Hyponatremia

... arginine vasopressin (AVP) receptor antagonist now availabl...Discovered and developed by Astellas, Vaprisol, an arginine vasopressin (AVP) receptor antagonist, is the firs... often results from elevated levels of the hormone arginine vasopressin (AVP), which regulates water and salt ...

NACCHO to Support Influenza Vaccination Efforts With Donation of Up to One Million Doses of FluMist(R)

...ained in the vaccine. FluMist is contraindicated in individuals with history of hypersensitivity to eggs, egg proteins, gentamicin, gelatin or arginine or with life-threatening reactions to previous influenza vaccinations, and in children and adolescents receiving concomitant aspirin or aspirin-contai...

New method to overcome multiple drug resistant diseases developed by Stanford researchers

...rom Professor of Chemistry at Stanford University. arginine is an amino acid, the building block of proteins, ...ade cells." Wender's team used a necklace of eight arginine molecules to surround the medication they worked w...nt cells, and restore it to effectiveness using an arginine transporter," Wender said. "This bodes well for us...

Efficacy of FluMist(R) in Children Highlighted at Pediatric Academic Societies Meeting

...B contained in the vaccine. FluMist is contraindicated in individuals with history of hypersensitivity to eggs, egg proteins, gentamicin, gelatin or arginine or with life-threatening reactions to previous influenza vaccinations, and in children and adolescents receiving concomitant aspirin or aspirin-contai...

Novel mechanism found that may boost impaired function of leukemia protein

...rning genes on or off. The researchers found that the cellular pathways that regulate the activity of the normal AML1 protein through a process called arginine methylation cannot similarly regulate the activity of AML1-ETO, a protein associated with causing acute leukemia. Methylation is the process by whic...

MedImmune Prepared to Support Implementation of Expanded ACIP Recommendations for Influenza Vaccinations

...B contained in the vaccine. FluMist is contraindicated in individuals with history of hypersensitivity to eggs, egg proteins, gentamicin, gelatin or arginine or with life- threatening reactions to previous influenza vaccinations, and in children and adolescents receiving concomitant aspirin or aspirin-conta...

Hyperion Therapeutics Announces Enrollment of First Patient in Phase 2 Clinical Trial in Patients With Hepatic Encephalopathy

...increasing waste nitrogen excretion. Treatment of hyperammonemia also requires caloric supplementation and restriction of dietary protein; intravenous arginine is an essential component of therapy for patients with CPS, OTC, ASS, or ASL deficiency. In patients with deficiencies in enzymes of the urea cycle,...

European blood researchers receive award to pursue research opportunities in US

...etings. Dr. Alinari, of the Sragnoli Institute of Hematology and Medical Oncology in Italy, will pursue his research project, Role of the Protein arginine Methyltransferase 5 (PRMT5) in B Cell Transformation at The Ohio State University. This experience will enhance my ability to share and discuss my r...

USP announces 11 new proposed monographs for dietary supplements

...ones Tablets. Two monographs for single ingredient amino acid formulations, arginine capsules and arginine tablets also appeared in PF 33(6). PF is the journal through which USP offe...

Data Show Vaprisol(R) Is Effective & Safe in Promptly Increasing Serum Sodium Levels in Patients With Euvolemic or Hypervolemic Hyponatremia

... that Vaprisol promptly and safely increased [Na+] in patients with euvolemic and hypervolemic hyponatremia." Vaprisol is the first in a new class of arginine vasopressin (AVP) receptor antagonists. Vaprisol blocks both V1a and V2 vasopressin receptors, resulting in increased urine output without increased s...
Arginine in Medical Technology

GNC Unveils Study Results for First and Only Nitric Oxide Product Clinically Proven to Improve Physical Performance at NSCA Conference in Las Vegas

...e groups - a. placebo (microcrystalline cellulose), b. 1.5 gm of micronized arginine and 300 mg of grape seed extract, and c. 3.0 gm of micronized arginine and 300 mg of grape seed extract. Amplified Maxertion N.O. is part ...

Nventa Develops Proprietary Vaccine Adjuvant

...tCall/ -- Nventa Biopharmaceuticals Corporation (TSX: NVN) today announced that the company has developed a proprietary vaccine adjuvant, Poly IC-Poly arginine (Poly-ICR), that has broad potential for use in both therapeutic and prophylactic vaccines. (Logo: http://www.newscom.com/cgi-bin/prnh/20080303/LAM...

Starting Flu Vaccination in August Could Help Protect Nearly 11 Million More Children During Scheduled Doctors' Visits

...B contained in the vaccine. FluMist is contraindicated in individuals with history of hypersensitivity to eggs, egg proteins, gentamicin, gelatin or arginine or with life-threatening reactions to previous influenza vaccinations, and in children and adolescents receiving concomitant aspirin or aspirin-contai...

Study Shows VAPRISOL(R) is Effective in Increasing Serum Sodium Levels and Well-Tolerated in Patients With Euvolemic or Hypervolemic Hyponatremia

... underlying conditions such as pneumonia, chronic obstructive pulmonary disease and impaired heart function." VAPRISOL is the first in a new class of arginine vasopressin (AVP) receptor antagonists. VAPRISOL blocks both V1a and V2 vasopressin receptors, resulting in increased urine output without increased s...

One Year Study of Exenatide Treatment Showed Improved Beta-Cell Function

...rgine, showed significant improvements in beta-cell function as measured by arginine and glucose induced C-peptide (a peptide associated with insulin production...e significantly improved beta-cell function as measured by both glucose and arginine induced insulin secretion." The side effects associated with exenatide tre...

One Year Study of Exenatide Treatment Showed Improved Beta-Cell Function

...rgine, showed significant improvements in beta-cell function as measured by arginine and glucose induced C-peptide (a peptide associated with insulin production...e significantly improved beta-cell function as measured by both glucose and arginine induced insulin secretion." The side effects associated with exenatide tre...

Study Shows Vasopressin Receptor Antagonist VAPRISOL(R) (Conivaptan Hydrochloride Injection) Significantly Increased Serum Sodium Concentration in Patients with Euvolemic & Hypervolemic Hyponatremia

...kely address an important clinical need for euvolemic or hypervolemic hyponatremia in hospitalized patients." VAPRISOL is the first in a new class of arginine vasopressin (AVP) receptor antagonists. VAPRISOL blocks both V1a and V2 vasopressin receptors, resulting in increased urine output without increased s...

Gilead Announces Presentation of Positive Phase III Data on Aztreonam Lysine for Inhalation in Patients With Cystic Fibrosis

...ith CF who have pulmonary P. aeruginosa. Aztreonam has potent activity against Gram-negative bacteria such as P. aeruginosa. Aztreonam formulated with arginine is a FDA-approved agent for intravenous administration. Aztreonam lysine for inhalation is a proprietary inhaled formulation of aztreonam and has been...

Gilead Announces Achievement of Primary Efficacy Endpoint in Second Phase III Study of Aztreonam Lysine for Inhalation in Patients With Cystic Fibrosis

...ith CF who have pulmonary P. aeruginosa. Aztreonam has potent activity against Gram-negative bacteria such as P. aeruginosa. Aztreonam formulated with arginine is a FDA-approved agent for intravenous administration. Aztreonam lysine for inhalation is a proprietary inhaled formulation of aztreonam and has been...
Arginine in Medical Products

DIASTAT™ Anti-CCP

Description:...-based test, DIASTAT Anti-CCP* is an ELISA based on the detection of autoantibodies against the cyclic citrullinated peptide (CCP) containing modified arginine residues in human serum or plasma. Enabling early and accurate diagnosis of RA, the Anti-CCP assay provides an additional tool in the diagnosis and ma...
Company:Inverness Medical Innovations

ACTH RIA Test

Description:...ly 20 minutes [1]. ACTH is secreted in response to corticotropin-releasing factor (CRF) from the hypothalamus [1]. The actions of CRF are augmented by arginine vasopressin. Several other stimulatory and inhibitory factors, including catecholamines and cytokines, may also play an important role in ACTH secreti...
Company:Diagnostic Systems Laboratories, Inc.
Arginine in Medical Dictionary

Hormone

...physicians may be fielding more questions about compounded hormone therapies — or, more commonly, Antidiuretic hormone , also known commonly as arginine vasopressin, is a nine ... Within hypothalamic neurons, the hormone is packaged in secretory vesicles with ... Only a small amount of hormo...

ADH

... arginine vasopressin (AVP), also known as vasopressin, argipressin or antidiuretic ...ow, the pituitary releases less ADH . ... ADH (Antidiuretic Hormone, arginine Vasopressin, AVP, Vasopressin) information center covers description, prepa...
Arginine in Biological News

The neurobiology of musicality related to the intrinsic attachment behavior?

...ons in music (p To elucidate the neurobiological basis of music in human evolution and communication the researchers demonstrated an association of arginine vasopressin receptor 1A (AVPR1A) gene variants with musical aptitude. In the previous studies the AVPR1A gene and its homologies have been associated ...

Pulmonary hypertension in children may result from reduced activity of gene regulator

...tric oxide production, making bad matters worse. Nitric oxide synthase uses arginine to make nitric oxide and ADMA, an arginine analogue, can bind to the nitric oxide precursor so it instead becomes a so...

Malaria parasite zeroes in on molecule to enhance its survival, team finds

...owth. Scanning the data, the scientists noted that arginine levels dramatically dipped by the end of one 48-ho...iments showed that the parasite doesn't break down arginine in order to grow, suggesting that this process ser... P. falciparum proliferate within the human body. arginine is an essential fuel for the human body's immune s...

UC Davis researchers discover Achilles' heel in pancreatic cancer

...mune function and hormone regulation. By depleting arginine levels in cell cultures and animal models, the tea...ng that the majority of pancreatic cancers require arginine for cell growth because of an inability to synthes...lines with lowest levels, the researchers depleted arginine levels in cultures of pancreatic cell lines using...

Researchers discover how stealthy HIV protein gets into cells

...sitively charged amino acid should do the trick. But when they replaced the arginine in the protein with other positively charged amino acids, it lost its funct...o bring materials through the membrane. Further analysis showed that the arginine was interacting with the head groups on the membrane lipids in a way that c...

Breakthrough developments in rheumatoid arthritis reported

...ontact with arginine, one of 20 common amino acids in proteins. When one of the enzymes is present, nitrogen is removed from the chemical structure of arginine and it converts into citrulline. Laboratories have developed a test to measure for anti-cyclic citrullinated peptide antibody, or anti-CCP. It...

Runners -- Let thirst be your guide

...r occurs when endurance exercisers drink more fluid than their kidneys can excrete. The hormone that determines how much fluid a kidney can excrete is arginine vasopressin (AVP), which is released from the pituitary gland when a person is becoming dehydrated in order to force the kidneys to conserve water. At...

Are dancers genetically different than the rest of us? Yes, says Hebrew University researcher

... in an examination of 85 dancers and advanced dancing students in Israel variants of two genes that provide the code for the serotonin transporter and arginine vasopressin receptor 1a. Both genes are involved in the transmission of information between nerve cells. The serotonin transporter regulates the l...

Newly discovered genetic disease sheds light on body's water balance

...boy had a unique mutation affecting the amino acid arginine at position 137 (R137). The single nucleotide change resulted in one baby having a change from arginine to cysteine (R137C). This same mutation was carrie...d by his mother. The other child had a change from arginine to leucine (R137L) but the mother is normal, sugge...
Arginine in Biological Technology

HHS Awards MedImmune Contract to Manufacture Live Attenuated Nasal Spray Vaccine for Novel Influenza A (H1N1)

...ontained in the vaccine. FluMist is contraindicated in individuals with history of hypersensitivity to eggs, egg proteins, gentamicin, gelatin or arginine or with life- threatening reactions to previous influenza vaccinations, and in children and adolescents receiving concomitant aspirin or aspirin-conta...

Nventa Biopharmaceuticals Announces Third Quarter 2008 Financial Results and Recent Corporate Highlights

...PV) therapeutics. o Nventa presented positive data from preclinical studies using its proprietary Toll-like Receptor 3 agonist, Poly IC-Poly arginine (Poly-ICR), at the World Vaccine Congress 2008 in Lyon, France. Study results demonstrated Poly-ICR to be a potent vaccine adjuvant ...

FDA Approves Astellas' Vaprisol(R) (Conivaptan Hydrochloride Injection) Premixed in 5% Dextrose for the Treatment of Hyponatremia

... arginine vasopressin (AVP) receptor antagonist now approved...Discovered and developed by Astellas, Vaprisol, an arginine vasopressin (AVP) receptor antagonist, is the firs... often results from elevated levels of the hormone arginine vasopressin (AVP), which regulates water and salt ...

United Therapeutics Reports Third Quarter 2007 Financial Results

... $1.5 million related to an impairment charge against the book value of our arginine patents. The impairment charge, using a discounted cashflow methodology, is...to reevaluate our assumptions used in determining the recoverability of our arginine patents. The increase in sales and marketing related expenses is primarily ...

ESR1 Gene Expression in Oncology and Metabolic Diseases Using the ASCENTATM System Target Validation and Identification of Novel Disease Indications

...athways are titled "CARM1 and Regulation of the Estrogen Receptor" and "Pelp1 Modulation of Estrogen Receptor Activity". CARM1 (coactivator-associated arginine methyltransferase) methylates many proteins that modulate transcriptional regulation and is a coactivator of gene transcription for ESR1. Pelp1 (Proli...

New BL21-CodonPlus Cells Correct Codon Bias in GC-Rich Genomes

...hosts. In GC-rich genomes, such as mammals, rare arginine codons (AGG or AGA) and the proline codon (CCC) mo...h, the problematic codons for expression are the arginine codon AGG (recognized by the tRNA product of the a... and proL. The corresponding tRNAs recognize the arginine codons, AGA/AGG, and the proline codon, CCC, res...

Codon Bias-Adjusted BL21 Derivatives for Protein Expression

...oblems for high-level expression in E. coli. The arginine codons AGG and AGA are recognized by the same tR...ation. AGG arginine AGA arginine CGA...

High-Level Expression of Peanut Allergens Affected by Rare Codon Usage

...aryotic expression system. Comparing Different Expression Vectors and E. coli Strains Several results from expression experiments suggest that arginine codons AGG and AGA can have pronounced effects on the translation efficiency of cloned genes in E. coli. 2 These codons are the least frequently ...
Arginine in Biological Products

Rabbit Anti-ARG. Vasopressin Polyclonal Antibody, Unconjugated from GeneTex

Description:... to ARG. Vasopressin The antibody blocks with the arginine vasopression peptide. Cells are found in the parav...rat brain of 4% FA perfused tissue. Immunogen: arginine Vasopression Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 Specificity: Blocks arginine vasopression peptide...
Company:GeneTex

Rabbit Anti-Arg Vasopressin Polyclonal Antibody, Unconjugated from ImmunoStar, Inc.

Description:... Raised to arginine vasopressin coupled to bovine thyroglobulin with carbodiimide ....
Company:ImmunoStar, Inc.

Nitric Oxide Synthase Radiometric Assay Kit from Cayman Chemical

Description:...ssay kit measures NOS activity by monitoring the conversion of radiolabeled arginine to citrulline. This assay is simple, sensitive, and specific for NOS activi...udes sufficient materials and reagents for 50 total reactions. Radiolabeled arginine and NADPH are not included with the kit....
Company:Cayman Chemical

Cation Exchange ProteinChip Arrays from Ciphergen

Description:...erize proteins directly on the chip. Cationic arrays bind proteins through electrostatic interaction of positively charged amino acids such as lysine, arginine and histidine. Binding occurs at low pH with low salt; binding decreases as pH and salt concentration increase. ProteinChip WCX2: is a weak cation exc...
Company:Ciphergen

Mouse Anti-PRMT5 Monoclonal Antibody, Unconjugated, Clone PRMT5-21 from GeneTex

Description:... Mouse monoclonal [PRMT5-21] to PRMT5 arginine methylation is an irreversible post translational modification which has on...MT members have been developed. These antibodies can be utilized to explore arginine methylation and its regulatory functions. Immunogen: Antibody was produc...
Company:GeneTex
Arginine in Biological Definition

Amino acid

...e , threonine , tryptophan , valine , and (in children) histidine and arginine . General structure of an amino acid The general structure of protei... hydrophilic 146.15 5.65 2.17 9.13 R Arg arginine basic 174.20 10.76 1.82 8.99 12.48 S Ser ...

Chromatin

...ith the cessation of transcription and involves nuclear protein exchange. The histones are mostly displaced, and replaced by protamines , small, arginine -rich proteins. Figure 2: Different levels of DNA condensation. (1) Single DNA strand. (2) Chromatin strand ( DNA with histones ). ...

Genetic code

...ine CAG (Gln/Q) Glutamine CGU (Arg/R) arginine CGC (Arg/R) arginine CGA (Arg/R) arginine CGG (Arg/R)...

Genetic code

...ine CAG (Gln/Q) Glutamine CGU (Arg/R) arginine CGC (Arg/R) arginine CGA (Arg/R) arginine CGG (Arg/R)...

Histone

... play a role in gene regulation in an epigenetic manner. Regulation occurs at the TATA box . Structure Histones are rich in lysine and arginine and are water-soluble. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their glo...

Hormone

...p30) adrenocorticotropic hormone (ACTH, also corticotropin) angiotensinogen and angiotensin antidiuretic hormone (ADH, also vasopressin, arginine vasopressin, AVP) atrial-natriuretic peptide (ANP, also atriopeptin) calcitonin cholecystokinin (CCK) corticotropin-releasing hormone ...

Signal transduction

...second messenger The gas nitric oxide is a free radical which diffuses through the plasma membrane and affects nearby cells. NO is made from arginine and oxygen by the enzyme NO synthase , with citrulline as a by-product. NO works mainly through activation of its target receptor, the enzyme sol...

Urea cycle

...P → 2 ADP PP i + H 2 O → 2 P i argininosuccinate → arginine + fumarate ( catalyzed by argininosuccinase) arginine + H 2 O → ornithine + urea ( catalyzed by arginase ) ornith...
Arginine in Biological Dictionary

Hormone

... involved. adrenocorticotropic hormone (ACTH, also corticotropin) angiotensinogen and angiotensin. antidiuretic hormone (ADH, also vasopressin, arginine vasopressin, AVP) ... Thyroid hormone disorders: focusing on the role of thyroid hormone in the body ... For example, thyroid hormone recepto...

Amino acid

... amino acid supplements on the market. ... Amino acids are the building blocks of proteins and muscle tissue. ... In addition to BCAAs, arginine is another amino acid that may benefit bodybuilders. ... An amino acid ... The Amino Acids Used to Synthesize Proteins. More than 300 ...
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