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Aplastic in Medical News

Cimzia(R) (certolizumab pegol) Now Available for Self-Administration in Adult Patients With Moderate to Severe Crohn's Disease

...ZIA remains unclear. Exercise caution in considering the use of CIMZIA in patients with these disorders. Rare reports of pancytopenia, including aplastic anemia, have been reported with TNF blockers. Medically significant cytopenia (e.g., leukopenia, pancytopenia, thrombocytopenia) has been infrequently...

UCB's CIMZIA(R) (certolizumab pegol) Approved by the U.S. FDA for Adult Patients Suffering From Moderate to Severe Rheumatoid Arthritis

...A remains unclear. Exercise caution in considering the use of CIMZIA in patients with these disorders. Rare reports of pancytopenia, including aplastic anemia, have been reported with TNF blockers. Medically significant cytopenia (e.g., leukopenia, pancytopenia, thrombocytopenia) has been infrequently...

UBC research finds molecular "key" to successful blood stem cell transplants

... could help increase the success of blood stem cell transplants, a procedure currently used to treat diseases such as leukemia, Hodgkin's lymphoma and aplastic anemia. During a blood stem cell transplant, donor blood stem cells - which can produce red and white blood cells and platelets - are injected into...

Survey: Few physicians support private banking of umbilical cord blood

...ivately if a relative has, or is at risk for, a disease such as leukemia or aplastic anemia that can be treated by a stem cell transplant. Families without suc...idual's own cord blood to treat high-risk neuroblastoma, or to treat severe aplastic anemia in the absence of an available sibling donor. In addition, few wo...

European Commission and United States Food and Drug Administration (FDA) Both Approve New Options for Patients With Certain Primary Brain Tumors

...ence myelosuppression including prolonged pancytopenia, which may result in aplastic anemia, which in some cases has resulted in a fatal outcome. In some cases, exposure to concomitant medications associated with aplastic anemia including carbamazepine, phenytoin, and sulfamethoxazole/trimethopri...

IMPACT Study Demonstrates That Longer Prophylactic Therapy With Valcyte(R) (Valganciclovir Hydrochloride Tablets) Increases Protection Against CMV - the Most Serious Viral Infection Affecting Transplant Patients

...icro liter, or the hemoglobin is less than 8 g/dL. Severe leucopenia, neutropenia, anemia, thrombocytopenia, pancytopenia, bone morrow depression, and aplastic anemia have been observed in patients treated with Valcyte tablets (and ganciclovir). Other adverse events reported with frequency of greater or equal...

Schering-Plough Completes Enrollment of Boceprevir Registration Studies in Treatment-Naive and Treatment-Experienced HCV Patients

..., retinal hemorrhage, cotton wool spots, papilledema, ischemic and hemorrhagic cerebrovascular events, bone marrow toxicity (cytopenia and very rarely aplastic anemia), thyroiditis, dental and periodontal disorders, hemorrhagic/ischemic colitis, dyspnea, pulmonary infiltrates, pneumonia, interstitial pneumoni...

PEGASYS(R) Proven Effective as Hepatitis C Treatment for Latino Patients, According to Article in The New England Journal of Medicine

...ttempt, suicide, psychotic disorder and hallucinations), serious and severe bacterial infections (sepsis), bone marrow toxicity (cytopenia and rarely, aplastic anemia), cardiovascular disorders (hypertension, supraventricular arrhythmias and myocardial infarction), hypersensitivity (including anaphylaxis), en...

Bioreactors might solve blood-platelet supply problems

...perly, such as certain cancer chemotherapy patients, bone marrow transplant patients, trauma patients given massive blood transfusions and people with aplastic anemia. The concentrates from volunteer donors are expensive to make, require 10 or more tests for pathogens and have a shelf life of only five days....

Schering-Plough Announces FDA Approval of PEGINTRON(TM) and REBETOL(R) Combination Therapy for Treating Pediatric Hepatitis C

..., retinal hemorrhage, cotton wool spots, papilledema, ischemic and hemorrhagic cerebrovascular events, bone marrow toxicity (cytopenia and very rarely aplastic anemia), thyroiditis, dental and periodontal disorders, hemorrhagic/ischemic colitis, dyspnea, pulmonary infiltrates, pneumonia, interstitial pneumoni...
Aplastic in Medical Technology

Soliris Effective in PNH Patients With History of Aplastic Anemia and Myelodysplastic Syndromes

- Analysis of Phase III Data Presented at ASCO - CHICAGO, June 04, 2007 /PRNewswire-FirstCall/ -- Investigators reported today that Soliris(TM) (eculizumab), a new treatment for paroxysmal nocturnal hemoglobinuria (PNH) developed by Alexion Pharmaceuticals, Inc. , is effective in patients diagnose...

SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

...odies and, rarely, in the development of a lupus-like syndrome. There have been postmarketing reports of pancytopenia, leukopenia, neutropenia, aplastic anemia, and thrombocytopenia in patients receiving TNF blockers. Cytopenias including pancytopenia, have been infrequently reported with SIMPONI in c...

IMPACT Study Showed Longer Valcyte(R) (valganciclovir hydrochloride tablets) Treatment Demonstrated Better Protection Against Cytomegalovirus (CMV) Disease One Year Post-Transplant

...icro liter, or the hemoglobin is less than 8 g/dL. Severe leukopenia, neutropenia, anemia, thrombocytopenia, pancytopenia, bone marrow depression, and aplastic anemia have been observed in patients treated with Valcyte tablets (and ganciclovir). Other adverse events reported with frequency of greater than or ...

Video: Partnership Unites UCB with Consumer Product Innovator OXO(R)

...IA remains unclear. Exercise caution in considering the use of CIMZIA in patients with these disorders. Rare reports of pancytopenia, including aplastic anemia, have been reported with TNF blockers. Medically significant cytopenia (e.g., leukopenia, pancytopenia, thrombocytopenia) has been infrequently...

Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting

..., retinal hemorrhage, cotton wool spots, papilledema, ischemic and hemorrhagic cerebrovascular events, bone marrow toxicity (cytopenia and very rarely aplastic anemia), thyroiditis, dental and periodontal disorders, hemorrhagic/ischemic colitis, dyspnea, pulmonary infiltrates, pneumonia, interstitial pneumoni...

Ground-Breaking Combination of All-Oral Agents Demonstrates Potential as Hepatitis C Treatment Regimen

...ttempt, suicide, psychotic disorder and hallucinations), serious and severe bacterial infections (sepsis), bone marrow toxicity (cytopenia and rarely, aplastic anemia), cardiovascular disorders (hypertension, supraventricular arrhythmias and myocardial infarction), hypersensitivity (including anaphylaxis), en...

Roche and Pharmasset Initiate Phase IIb Clinical Trial of R7128, Most Advanced Nucleoside Polymerase Inhibitor in Development for Chronic Hepatitis C

...ttempt, suicide, psychotic disorder and hallucinations), serious and severe bacterial infections (sepsis), bone marrow toxicity (cytopenia and rarely, aplastic anemia), cardiovascular disorders (hypertension, supraventricular arrhythmias and myocardial infarction), hypersensitivity (including anaphylaxis), en...

Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients

..., retinal hemorrhage, cotton wool spots, papilledema, ischemic and hemorrhagic cerebrovascular events, bone marrow toxicity (cytopenia and very rarely aplastic anemia), thyroiditis, dental and periodontal disorders, hemorrhagic/ischemic colitis, dyspnea, pulmonary infiltrates, pneumonia, interstitial pneumoni...

FDA Approves an Expanded Indication for Peginterferon-Based Combination Therapy for Patients With Chronic Hepatitis C

..., retinal hemorrhage, cotton wool spots, papilledema, ischemic and hemorrhagic cerebrovascular events, bone marrow toxicity (cytopenia and very rarely aplastic anemia), thyroiditis, dental and periodontal disorders, hemorrhagic/ischemic colitis, dyspnea, pulmonary infiltrates, pneumonia, interstitial pneumoni...

Alexion Reports Positive Results from AEGIS Registration Study of Soliris in Japanese Patients With PNH

...l to 30x10(9)/L). Forty-five percent of the AEGIS patients had a history of aplastic anemia or myelodysplastic syndromes. Patients were dosed in accordance with...d more commonly among patients with disorders of the bone marrow, including aplastic anemia (AA) and myelodysplastic syndromes (MDS). (8,9,10) In patients with ...
Aplastic in Medical Definition

Hematopathology

...sis , Warm autoimmune hemolytic anemia , Hemolytic-uremic syndrome , Microangiopathic hemolytic anemia , Paroxysmal nocturnal hemoglobinuria ) • aplastic anemia : ( Acquired pure red cell aplasia , Fanconi anemia ) • Hemochromatosis Coagulation / platelets DIC • Hemophilia ( A , B , ...

Pathology

...sis , Warm autoimmune hemolytic anemia , Hemolytic-uremic syndrome , Microangiopathic hemolytic anemia , Paroxysmal nocturnal hemoglobinuria ) • aplastic anemia : ( Acquired pure red cell aplasia , Fanconi anemia ) • Hemochromatosis Coagulation / platelets DIC • Hemophilia ( A , B , ...
Aplastic in Medical Dictionary

Aplastic

Aplastic anaemia is a condition where bone marrow does not produce sufficient new cells to replenish blood cells. Aplastic anemia is a blood disorder in which the body's bone marrow doesn't make ... Treatments for aplastic anemia include blood transfusions, blood and ma...

Nose bleeds

...ook like a gallon of blood is coming from your nose ! Read this article to find out what ... nose may break and bleed , causing ... Acquired aplastic Anemia - nose bleeds . Acquired prothrombin deficiency - nosebleeds ... Acute promyelocytic leukemia - nose bleeds . more causes... Re...

Hemolytic crisis

...auses acute (and often severe) anemia, because the body ... Transient aplastic Crisis in Hemolytic Anemias. All people with hemolytic anemias rely on high ... Chronic hemolytic anemia. Transient aplastic crisis ... Hemolytic crisis is the rapid destruction of red blo...

Hemolytic anemia

... Anemia is the most common form of ... Anemia is defined by a reduced amount of red blood cell volume ... Cell Anemia . Hemolytic Anemia . aplastic Anemia . Iron ... ... 118 disease causes of Hemolytic anemia , patient stories, diagnostic guides, ... Misdiagnosis and Hemolytic anemia ...

Blood disorders

...disorders , including anemia, neutropenia, neutrophilia, ... Blood Disorders . Problems in Prenatal Development of the Digestive Tract. Anemia. aplastic Anemia ... Hematology and Blood Disorders . Iron Deficiency Anemia. Leukemia ... Find out about anemia and blood disorders , potential tre...

Aplastic anemia

... aplastic anaemia is a condition where bone marrow doe... produce sufficient ... Treating immune-mediated aplastic anemia involves suppression of the immune ... aplastic anemia is a blood disorder in which the body'...
Aplastic in Biological News

Peter Baumann named Howard Hughes Medical Institute Early Career Scientist

...rch team hopes to lay the foundation for the development of treatments for cancer as well as degenerative syndromes such as dyskeratosis congenita and aplastic anemia. Dr. Baumann leads an eight-person team at the Stowers Institute composed of postdoctoral researchers, graduate students, and scientific st...

Stowers Institute's Baumann Lab identifies key step in maturation pathway of telomerase

...g machinery for human telomerase are also likely to compromise telomerase function and may thus contribute to diseases such as dyskeratosis congenita, aplastic anemia, and idiopathic pulmonary fibrosis." ...

Vidaza receives positve opinion from European CHMP

... The aplastic Anemia & MDS International Foundation is pleased to inform patients that th...ts in Europe with this disease," said John Huber, Executive Director of the aplastic Anemia & MDS International Foundation, "Vidaza not only extends patients' l...

FDA approves Vidaza label expansion

... Washington D.C. (August 21, 2008) The aplastic Anemia & MDS International Foundation (AA&MDSIF) is pleased to inform patie...tend survival for MDS patients," said John Huber, Executive Director of the aplastic Anemia and MDS International Foundation. "We are excited to see that in th...

Biochemists report discovery of structure of major piece of telomerase; implications for cancer

...roscopy. Mutations in the RNA are associated with the inherited diseases aplastic anemia and dyskeratosis congenita, which frequently are manifested by progr...d of the RNA, which is essential for the function of the enzyme, and causes aplastic anemia in patients who have this mutation. "There are five known disease...
Aplastic in Biological Technology

Cimzia(R) (certolizumab pegol) Provides Long-Term Remission and Response Rates in Infliximab-Refractory Crohn's Patients

...ZIA remains unclear. Exercise caution in considering the use of CIMZIA in patients with these disorders. Rare reports of pancytopenia, including aplastic anemia, have been reported with TNF blockers. Medically significant cytopenia (e.g., leukopenia, pancytopenia, thrombocytopenia) has been infrequently...

Transplant Program Tops in Expected One-Year Survival Rate

...ge, patient age and degree of donor cell match. Stem-cell and bone-marrow transplants are used to treat various leukemias, lymphomas and severe aplastic anemia. "The study's findings reflect the extraordinary and longtime dedication by the staff of the Hutchinson Center and SCCA to improve the o...

Soliris(R) Reduced Measures of Thrombosis and Inflammation, and Decreased Indicators of Pulmonary Hypertension, in Studies of Patients with PNH

...d 15 years from the time of diagnosis. (4,6) PNH has been identified more commonly among patients with disorders of the bone marrow, including aplastic anemia (AA) and myelodysplastic syndromes (MDS). (7, 8, 9). In patients with thrombosis of unknown origin, PNH may be an underlying cause. (5,10) ...

New Data Suggest CIMZIA(R) (Certolizumab Pegol) Active in Treating Moderate to Severe Crohn's Patients With Fistulizing Disease

... unclear. Exercise caution in considering the use of CIMZIA (R) in patients with these disorders. Rare reports of pancytopenia, including aplastic anemia, have been reported with TNF blockers. Medically significant cytopenia (e.g., leukopenia, pancytopenia, thrombocytopenia) has been infrequently...

Alexion's Soliris(R) Receives 2008 Prix Galien USA Award for Best Biotechnology Product

... 10 and 15 years from the time of diagnosis. (2,4) PNH has been identified more commonly among patients with disorders of the bone marrow, including aplastic anemia (AA) and myelodysplastic syndrome (MDS). (5,6,7,8,9) In patients with thrombosis of unknown origin, PNH may be an underlying cause. (3,9) Pri...

Cord Blood America CEO Matthew Schissler Interviewed by BIONOVA, Greece's Leading Biotech Magazine

...artnership in 2006 named a.bourkas Co., United. "Stem cells are used today in the treatment of leukemia, breast cancer, lymphoma, Hodgkin's Disease, aplastic anemia, sickle cell anemia, various other cancers, blood diseases, hereditary and genetic conditions and immune system disorders," Mr. Schissler said ...

Abbott's HUMIRA(R) Receives Positive Opinion From EMEA for Treatment of Moderate to Severe Plaque Psoriasis

...including HUMIRA, have been associated in rare cases with demyelinating disease and serious allergic reactions. Rare reports of pancytopenia including aplastic anemia have been reported with TNF-blocking agents. Adverse events of the haematologic system, including medically significant cytopenia have been inf...

Pharmion's Oral Azacitidine Granted Fast Track Status for Myelodysplastic Syndromes

...daza should not nurse. About MDS The highest prevalence of MDS is in patients over 60 years of age. According to the American Cancer Society and the aplastic Anemia and MDS International Foundation, there are approximately 10,000 - 30,000 new cases of MDS in the United States each year. Survival ranges from...

PNH Patients Treated with Soliris(TM) Experienced Dramatic Reduction in Blood Clots During Clinical Trials

...s as a result of their disease," said John Huber, Executive Director of the aplastic Anemia & MDS International Foundation. "This news provides additional hope ...d more commonly among patients with disorders of the bone marrow, including aplastic anemia (AA) and myelodysplastic syndrome (MDS).(14,15,16,17) In patients wi...

Analysis Of Chloramphenicol by Negative Ion Electrospray LC/MS/MS

...ility, and low cost. CAP can cause an irreversible illness called aplastic anemia. The incidence rate of aplastic anemia is one out of every 25,000 to 40,000 people. Onset may occur weeks o...
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