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Antivirals in Medical News

Surveyed Physicians Will Treat Over 50 Percent of Hepatitis C Genotype 1-Infected Patients With the Protease Inhibitor Telaprevir

...d Hepatitis C: Impact of and Receptivity to Novel antivirals Among Payers and Prescribers finds that, among th... Hepatitis C: Impact of and Receptivity to Novel antivirals Among Payers and Prescribers is based on a U.S. s...ions of Telaprevir, Boceprevir and Other Key Novel antivirals . This webinar will be held on Thursday, September...

Consumer Reports Swine Flu Survival Kit Prepares Consumers for Potentially Tough Flu Season This Fall

...oms of seasonal flu but also shorten its duration and possibly prevent complications as well. Some of those drugs probably help against swine flu too. antivirals work best if taken early on in the illness, so it's best to take them at the first sign of symptoms. Brands to Buy and Brands to Skip ...

Save Swine Flu Drugs for Younger Patients, Study Urges

...edict some important features of the ongoing influenza pandemic, the use of antivirals is confirmed to be the most effective single intervention, in the absence o...ossible to reduce morbidity and excess mortality by prioritizing the use of antivirals by age." "Although a policy of age-specific prioritization of antiviral ...

Pharmasset Nominates PSI-938 as a New Nucleotide Analog Inhibitor of Hepatitis C for Preclinical Development

...es, a higher barrier to resistance than other classes of HCV small molecules in development, and the potential to be combined with other direct acting antivirals targeting HCV. In addition, these purine analogs are also active against the S282T resistant variant selected in vitro by the pyrimidine analogs, an...

CDC: Flu Drugs Should Be 1st Choice for Pregnant Women With Swine Flu

... Rapid use of antivirals such as Tamiflu best for this high-risk group, agency says THUR...s to spread across the country, and that this high-risk group needs to take antivirals as soon as infection is suspected. "Pregnant women are at higher risk of...

Pregnant Women Should Take Flu Drugs Promptly

... CDC says quick use of antivirals such as Tamiflu best for this high-risk group WEDNESDAY, May 1...s to spread across the country, and that this high-risk group needs to take antivirals as soon as infection is suspected. "Pregnant women are at higher risk of...

Swine Flu Likely to Return to U.S. Next Winter

...ulent, said Ostrosky. "We've been very lucky so far that it's appearing to be mild, at least in the U.S., as far as virulence and susceptibility to antivirals is concerned," he said. "It could change. That's one of the concerns." "The severity depends on whether [and how] the genotype of the virus reassor...

Swine Flu Outbreak Not a Pandemic at This Point

... Kathleen Sebelius, has made the decision to buy 13 million more courses of antivirals to replenish the antiviral stockpile, Schuchat said. "We don't know if we a...she said. In addition, the United States has shipped 400,000 regimens of antivirals to Mexico, believed to be the source of the global outbreak, at the request...

Swine Flu Outbreak Not a Pandemic, Yet

... Kathleen Sebelius, has made the decision to buy 13 million more courses of antivirals to replenish the antiviral stockpile, Schuchat said. "We don't know if we a...she said. In addition, the United States has shipped 400,000 regimens of antivirals to Mexico, believed to be the source of the global outbreak, at the request...

Swine Flu Continues to Spread Across U.S.

... Kathleen Sebelius, has made the decision to buy 13 million more courses of antivirals to replenish the antiviral stockpile, Schuchat said. "We don't know if we a...on, in the last 24 hours, the United States has shipped 400,000 regimens of antivirals to Mexico, believed to be the source of the global outbreak, at the request...
Antivirals in Medical Technology

Roche, InterMune and Pharmasset Announce Initiation of INFORM-1, the First Dual-Combination Clinical Trial with Oral Antivirals in Hepatitis C

PRINCETON, N.J., Nov. 10 /PRNewswire-FirstCall/ -- Pharmasset, Inc. (Nasdaq: VRUS ), Roche (SWX: ROG) and InterMune, Inc. (Nasdaq: ITMN ) today announced that the first patients have been dosed in an innovative clinical trial in patients chronically infected with the hepatitis C virus (HCV)....

Trana Discovery and Southern Research Institute Announce the First RNA-RNA High Throughput Drug Screening Assay Platform for HIV Antivirals

Collaboration validates unique HIV assay system that identifies potential tRNA inhibitors CARY, N.C. and BIRMINGHAM, Ala., Sept. 17 /PRNewswire-USNewswire/ -- Trana Discovery, a drug discovery company, today announced the development of a high throughput screening (HT...

Idenix Pharmaceuticals Successfully Completes Proof-of-Concept Study of IDX184 for the Treatment of Hepatitis C Virus (HCV)

...hieving our ultimate goal of developing novel combinations of direct-acting antivirals for the treatment of hepatitis C." The company plans to report t...ing IDX184 or successful development of novel combinations of direct-acting antivirals for the treatment of hepatitis C. Such forward-looking statements involve k...

InterMune Reports Presentation of Triple Combination Study of ITMN-191 at European Association for the Study of the Liver (EASL)

...atment. INFORM-1 Program In November 2008, Roche, InterMune and Pharmasset initiated the first all-oral combination study of direct-acting antivirals (DAAs) in the absence of interferon or ribavirin, known as the INFORM-1 study. Interim results from the INFORM-1 study will be presented in an oral l...

Idenix Pharmaceuticals Initiates Proof-of-Concept Study of IDX184 for the Treatment of Hepatitis C Virus (HCV)

...ndidate, our goal in 2009 is to become the first biopharmaceutical company with innovative drugs from three major classes of direct-acting hepatitis C antivirals in clinical development." The proof-of-concept trial in HCV-infected patients is being conducted at multiple centers around the world. The trial...

Anadys Pharmaceuticals Announces Successful Outcome of ANA598 Healthy Volunteer Study and Finalization of Study Design for Phase Ib Trial in HCV Patients

...Anadys has previously reported data demonstrating that ANA598 retains undiminished activity against a number of HCV variants resistant to other direct antivirals currently in development. Clinical Need and Market Opportunity in HCV Infection Chronic HCV infection is a serious public health concern affecting...

Idenix Pharmaceuticals Advances HCV Discovery Program to Clinic

...V non-nucleoside and protease inhibitor programs, we are progressing toward our ultimate goal of developing a proprietary combination of direct-acting antivirals for the treatment of hepatitis C." IDX184 Nucleotide Prodrug Polymerase Inhibitor IDX184 is a once-daily, oral nucleotide prodrug candidate based ...

Anadys Pharmaceuticals Initiates Phase I Clinical Trial of ANA598

...tion studies. We expect the full benefit of direct antivirals to be demonstrated when studied as components of n...enzymes to inhibit viral replication. These direct antivirals are expected to improve overall therapy by increas... HCV infection and that the full benefit of direct antivirals will be demonstrated when studied as components of...

Human Genome Sciences Reports Progress With Late-Stage Products and New Initiatives

... a longer period of time than is seen with other long-acting interferons may make it an effective component of future combination treatment with novel antivirals for the treatment of chronic hepatitis C. Key milestones leading to a potential launch of Albuferon in 2010: -- Complete the treatment phase of A...

Romark Laboratories Completes Enrollment in U.S. Phase II Study of Nitazoxanide for Chronic Hepatitis C Genotype 1 Non-Responders

... Romark Laboratories (http://www.romark.com ), a privately held biopharmaceutical company, has discovered and developed a new class of small molecule antivirals known as thiazolides. The Company is developing nitazoxanide, the first of the thiazolide class, for the treatment of chronic hepatitis C, and is deve...
Antivirals in Biological News

Study: Excessive use of antiviral drugs could aid deadly flu

...name for oseltamivir phosphate), but found that fewer than 1 percent of all of the samples were resistant to that class of drugs. Different classes of antivirals target influenza in different ways in the hosts' cells. Janies and researchers from the University of Colorado and Kansas State University also des...

Masks, hand washing, prevent spread of flu-like symptoms by up to 50 percent

...s hand washing and masks---especially in a pandemic flu outbreak---are critical to study because pharmaceutical interventions such as vaccinations and antivirals may not be available in sufficient quantity for preventing and controlling pandemic influenza outbreaks. In February 2007, the Centers for Disease ...

Tamiflu effective for treatment and prevention of influenza in children 1 year and older

... stockpiling The World Health Organization (WHO) advises that stockpiling antivirals in advance is presently the only way to ensure that sufficient supplies are...overnments to ensure governments are aware of the importance of stockpiling antivirals in the event of a pandemic situation. Roche has received and fulfilled pand...

Experts predict Tamiflu could halve the pandemic influenza death toll versus no intervention

...l be available in the initial wave of a pandemic.” Prophylaxis with antivirals or vaccines Vaccination is the primary means of preventing influenza. ...hin the early months of the pandemic, making prophylaxis and treatment with antivirals a crucial part in the efforts to reduce the burden of pandemic influenza.4 ...

WHO data confirms low level of resistance to Tamiflu

...gainst a potential pandemic outbreak. WHO also reconfirmed that stockpiling antivirals - in particular oseltamivir- in advance is presently the only way to ensure...overnments to ensure governments are aware of the importance of stockpiling antivirals in the event of a pandemic situation. Roche has received and fulfilled pand...

Antivirals effectively curb influenza virus

...at there is a clear benefit to be gained by giving antivirals to people who have been exposed to the virus to pr...-based biostatistician. "While the efficacy of antivirals to protect against influenza is critical, the effe... affecting influenza virus in the nose. While both antivirals reduced cough, in earlier studies inhaled zanamivi...

UW scientists unravel critical genetic puzzle for flu virus replication

... antiviral drugs and the harnessing of benign influenza viruses as gene vectors to optimize vaccine production, Kawaoka says. "We need to have more antivirals for influenza," according to Kawaoka, "and as these segments get incorporated into the particle as a set, it suggests these elements could be a target...

New possibilities for flu antiviral and vaccine research emerge from 'Spanish flu' virus

...he specific genes responsible for its virulence, with the hope of designing antivirals or other interventions that would work against virulent pandemic or epidemi... interventions," Tumpey said. Although more research needs to be done on antivirals and vaccines for a future flu pandemic, Tumpey noted some encouraging signs...

Preventing a pandemic: Study suggests strategies for containing a flu outbreak

...igher. In all cases, early intervention would be essential. The authors note in their study that the current World Health Organization stockpile of antivirals for avian flu could probably be sufficient to help contain a pandemic in a population like the one in the model, if the stockpile were deployed within...

Biota makes major antiviral discovery

...ounced today that it has discovered a new class of orally-effective, potent antivirals against RSV (respiratory syncytial virus) infection. Biota has filed worldw... Latest results in two animal models also demonstrate that Biota's new RSV antivirals are effective when administered orally. This should allow the product to be...
Antivirals in Biological Technology

GlaxoSmithKline and Anacor Pharmaceuticals Form Alliance to Develop Systemic Antivirals and Antibiotics Based on Boron Chemistry

- Innovative approach to developing anti-infective medicines provides hope for combating problems of resistance - PALO ALTO, Calif. and LONDON, Oct. 8 /PRNewswire/ -- Anacor Pharmaceuticals and GlaxoSmithKline today announced that they have entered into a worldwide strategic all...

Anadys Pharmaceuticals Receives FDA Clearance of Phase II Protocol to Study ANA598 in Combination With Interferon-Alpha and Ribavirin in HCV Patients

...rd quarter 2009. Anadys has presented in vitro data supporting the use of ANA598 in combination with interferon-alpha as well as with direct antivirals currently in development. In particular, data has shown that ANA598 is synergistic in vitro with interferon-alpha as well as representative HCV pro...

BIO Visitors Bring Viral Preparedness to Atlanta

...turing plant. Merck already operates a biomanufacturing facility in Wilson. The state's biomanufacturing capabilities extend beyond vaccines and antivirals to include biologics, pharmaceuticals and diagnostics. The complete line-up includes products from more than 50 companies, including Biogen Idec, Novo...

Idenix Pharmaceuticals Reports Data From Three Hepatitis C Development Programs at the 44th Annual Meeting of the European Association for the Study of the Liver

..." said Jean-Pierre Sommadossi, Ph.D., chief executive officer of Idenix. "With drug candidates in each of the three major classes of direct-acting HCV antivirals in our pipeline, we believe that we are well positioned to design an optimal combination therapy." IDX184 Nucleotide Prodrug Polymerase Inhibit...

Idenix Pharmaceuticals Reports Fourth Quarter and Year End Financial Results

...f our resources on the advancement of our HCV programs, with the goal of having a drug candidate from each of the three major classes of direct-acting antivirals in the clinic." For the fourth quarter ended December 31, 2008, Idenix reported total revenues of $4.3 million, compared with total revenues of...

Romark Announces Presentation of New Data for Controlled Release Nitazoxanide in Chronic Hepatitis C

...ries Romark Laboratories ( www.romark.com ), a privately held biopharmaceutical company, has discovered and developed a new class of small molecule antivirals known as thiazolides. The Company is developing nitazoxanide, the first of the thiazolide class, for the treatment of chronic hepatitis C, and is deve...

ANA598 Receives Fast Track Designation From the FDA for the Treatment of Chronic Hepatitis C Infection

...of ANA598, one of the few non-nucleoside polymerase inhibitors in clinical development for the treatment of HCV. We continue to believe this class of antivirals holds great promise as a component of future HCV treatment regimens." About ANA598 Anadys recently initiated patient dosing in a ...

Romark Announces Presentation of New Data for Nitazoxanide in Chronic Hepatitis C at AASLD 2008

... Romark Laboratories (http://www.romark.com ), a privately held biopharmaceutical company, has discovered and developed a new class of small molecule antivirals known as thiazolides. The Company is developing nitazoxanide, the first of the thiazolide class, for the treatment of chronic hepatitis C, and is deve...

Romark Laboratories Announces Presentation of New Nitazoxanide Data at 59th Annual AASLD Meeting and 50th Anniversary IASL Meeting in San Francisco

... Romark Laboratories (http://www.romark.com ), a privately held biopharmaceutical company, has discovered and developed a new class of small molecule antivirals known as thiazolides. The Company is developing nitazoxanide, the first of the thiazolide class, for the treatment of chronic hepatitis C, and is deve...

BioCryst Reports Results From the First-Ever Completed Active-Controlled Phase 2 Study in Hospitalized Influenza

... patients who are hospitalized for influenza. The results indicate a potential role for antiviral therapy, which is critical as currently there are no antivirals approved for patients hospitalized for acute serious or potentially life-threatening influenza," said Dr. Michael Ison, Assistant Professor, Divisions...
Antivirals in Biological Products

Virology LabFax from Promega

Description:... D.R. Harper (1993) • Includes: essential information on taxonomy, culture and safe handling of viruses, immunology, monoclonal antibodies, antivirals and vaccines....
Company:Promega
Antivirals in Biological Definition

Hepatitis B

...chance of clearing the infection. Treatments are available in the form of antivirals such as lamivudine and adefovir and immune system modulators such as interferon alpha . There are several other antivirals under investigation. Roughly, all of the currently available treatments, w...
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