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Antipsychotics in Medical News

FDA Panel OKs Newer Antipsychotics for Children

Seroquel, Zyprexa and Geodon have been linked to certain health risks, experts note,, WEDNESDAY, June 10 (HealthDay News) -- A U.S. Food and Drug Administration advisory panel on Wednesday voted overwhelmingly that Seroquel and Zyprexa, two powerful antipsychotic drugs, be approved t...

FDA Panel Mulls Newer Antipsychotics for Kids

Seroquel, Zyprexa have been linked to certain health risks, experts note,, WEDNESDAY, June 10 (HealthDay News) -- A U.S. Food and Drug Administration advisory panel is expected to vote Wednesday on whether several powerful but controversial antipsychotic drugs be approved for use by ch...

Newer Antipsychotics May Boost Weight in Alzheimer's Patients

Drugs such as olanzapine, quetiapine may also lower 'good' cholesterol, researchers say WEDNESDAY, April 15 (HealthDay News) Newer antipsychotic drugs promote weight gain and lower levels of HDL ("good") cholesterol in Alzheimer's patients, according to a new study of more than 400 el...

Newer Antipsychotics Pose Cardiac Risk: Study

Patients advised to avoid the drugs in some cases WEDNESDAY, Jan. 14 (HealthDay News) -- A new study warns that the second generation of antipsychotic drugs, used to treat conditions ranging from schizophrenia to anxiety, put patients at higher risk of sudden death due to cardiac arres...

Most Newer Antipsychotics No Better Than Older Ones, Just Different

People need to find the one that works best for them, experts say FRIDAY, Dec. 5 (HealthDay News) -- Antipsychotic drugs have traditionally been classified as "first" or "second" generation, but these classifications aren't valid and the drugs should be prescribed on a patient-by-pati...

Newer antipsychotics no better than older drug in treating child and adolescent schizophrenia

Two newer atypical antipsychotic medications were no more effective than an older conventional antipsychotic in treating child and adolescent schizophrenia and may lead to more metabolic side effects, according to a new study funded by the National Institutes of Health's National Institute of Ment...

Short-term use of antipsychotics in older adults with dementia linked to serious adverse events

Older adults with dementia who receive short-term courses of antipsychotic medications are more likely to be hospitalized or die than those who do not take the drugs, according to a report in the May 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. Newer antipsychot...

Antidepressant as Good as Antipsychotics for Dementia

Study finds fewer side effects for Alzheimer's patients prone to hallucinations, delusions MONDAY, Sept. 10 (HealthDay News) -- The antidepressant citalopram (Celexa) may be as effective as often-prescribed antipsychotic drugs to control the agitation and psychotic symptoms associated...

Rutgers receives $2.3 million federal grant to research use, safety of antipsychotics

NEW BRUNSWICK, N.J. Rutgers, The State University of New Jersey, has received a $2.3 million grant from the federal Agency for Healthcare Research and Quality (AHRQ) and the Food and Drug Administration (FDA) to lead a major study of use, safety and effectiveness of antipsychotic medications. ...

FDA Orders Warning Label on Older Antipsychotics

Drugs increase risk of death among elderly patients with dementia, agency says MONDAY, June 16 (HealthDay News) -- The U.S. Food and Drug Administration is cautioning physicians that certain types of antipsychotic drugs can boost the death risk of seniors with dementia. Doctors som...
Antipsychotics in Medical Technology

Video: FDA Approves INVEGA(R) SUSTENNA(TM) for the Acute and Maintenance Treatment of Schizophrenia

...INVEGA ((R)) SUSTENNA(TM) is not approved for the treatment of dementia-related psychosis in elderly patients. Elderly patients who were given oral antipsychotics like INVEGA ((R)) SUSTENNA(TM) in clinical studies for psychosis caused by dementia (memory problems) had a higher risk of death. Neurolept...

FDA Advisory Committee Votes in Favor of Zyprexa for Two Adolescent Indications

... relative risk estimates are inconsistent, the association between atypical antipsychotics and increases in glucose levels appears to fall on a continuum and Zyprexa ...atment and periodically during treatment. Any patient treated with atypical antipsychotics should be monitored for symptoms of hyperglycemia including polydipsia, pol...

RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder

...s: Hyperglycemia, some cases extreme and associated with ketoacidosis, hyperosmolar coma or death has been reported in patients treated with atypical antipsychotics (APS), including RISPERDAL(R) CONSTA(R). Patients starting treatment with APS who have or are at risk for diabetes should undergo fasting blood glucos...

FDA Approves Vanda Pharmaceuticals' Fanapt(TM) for the Treatment of Schizophrenia

...l, which may lead physicians to consider prescribing Fanapt(TM) after other antipsychotics are tried first. About Schizophrenia Schizophrenia is a chronic de...he experience of adverse events. Worldwide sales from the class of atypical antipsychotics exceeded US $20 billion in 2007. About Vanda Vanda Pharmaceutical...

Lilly Announces Inconclusive Phase II Study Results for mGlu2/3 at the International Congress on Schizophrenia Research

...observed in three patients. Furthermore, LY2140023 monohydrate had a low association with adverse events commonly associated with currently available antipsychotics and showed no appreciable weight gain. Steven Paul, M.D., executive vice president, science and technology, and president, Lilly Research Labor...

FDA Issues a Complete Response Letter for Lilly's Olanzapine LAI for Treatment of Schizophrenia in Adults

...th oral and injected short-acting formulations, long-acting formulations of antipsychotics allow for stable concentrations of the active drug to remain at a therapeut... relative risk estimates are inconsistent, the association between atypical antipsychotics and increases in glucose levels appears to fall on a continuum and olanzapi...

Olanzapine Long-Acting Injection (LAI) Shown to Maintain Treatment Benefit in Schizophrenia for up to Six Months

...period of up to four weeks. Long-acting injectable antipsychotics have been associated with improved treatment of sc...usly stabilized dose. No supplementation with oral antipsychotics was permitted during the study. An assessment of...t-acting formulations, long-acting formulations of antipsychotics allow for stable concentrations of the active drug...

Olanzapine Long-Acting Injection (LAI) Data Presented at First Annual Schizophrenia International Research Society Conference

...th oral and injected short-acting formulations, long-acting formulations of antipsychotics allow for stable concentrations of the active drug to remain at a therapeut...ontrol. Persons with risk factors for diabetes who are starting on atypical antipsychotics should undergo baseline and periodic fasting blood glucose testing. Patient...

Data Presented at the American Psychiatric Association (APA) Annual Meeting Demonstrate Iloperidone's Efficacy and Safety, With Low Rates of Movement and Metabolic Adverse Events

...l antipsychotic medications and revealed that 74 percent of patients taking antipsychotics discontinued treatment within 18 months, primarily because of insufficient ...rience, individual patients may have very different responses to individual antipsychotics and one of the frustrating parts of trying new medications is that we have ...

Statement from Eli Lilly and Company: Response to Connecticut Attorney General News Release

... relative risk estimates are inconsistent, the association between atypical antipsychotics and increases in glucose levels appears to fall on a continuum and olanzapi...ontrol. Persons with risk factors for diabetes who are starting on atypical antipsychotics should undergo baseline and periodic fasting blood glucose testing. Patient...
Antipsychotics in Biological News

Risks and benefits of antipsychotics in children and adolescents

This release is available in Spanish . Background Many of the psychiatric disorders observed in adults have their onset in childhood or adolescence. In fact some studies show that at least 20% of children and adolescents will fulfil a diagnostic criterion for a mental disorder before r...

New treatment mechanisms for schizophrenia

...uthor, notes: Certain pharmaceuticals used to treat schizophrenia interact with this receptor. Our results indicate that especially so-called atypical antipsychotics may promiscuously exert some of their beneficial effects through the 5-HT7 receptor. Further exploration of this receptor as a treatment target may le...

Studies look at how genes affect antipsychotic drug response

...an increased chance at medication response literally could change their lives," Bishop said. "While we know a great deal about the pharmacology of antipsychotics like risperidone, there is still much to learn about their influence on cognition and brain function, as well as how genetics affect overall medicatio...

Engineered mouse mimics cognitive aspects of schizophrenia

...gnitive deficits of patients with schizophrenia, our data could explain why antipsychotics do not greatly ameliorate cognitive deficits," wrote the researchers. "The ...tic episode, when treatment usually commences. Thus, treatment with typical antipsychotics may be too late to reverse the physiological alterations that are responsib...

FDA Warns About Antipsychotic Drugs and Elderly

...s of death were varied, most seemed to be either heart-related (such as heart failure or sudden death) or from infections (pneumonia). The atypical antipsychotics fall into three drug classes based on their chemical structure. Because the increase in mortality was seen with atypical antipsychotic medications in ...
Antipsychotics in Biological Technology

SAPHRIS(R) (asenapine) Meets Primary Endpoint in Long-Term Extension Study in Patients With Predominant, Persistent Negative Symptoms of Schizophrenia

...min Szegedi, M.D., Ph.D., vice president, global clinical research, central nervous system, Schering-Plough Research Institute. "Few studies with the antipsychotics currently available on the market have been designed specifically to evaluate long-term effects on predominant, persistent negative symptoms. The res...

Vanda Pharmaceuticals to Present Data on Fanapt(TM) and Tasimelteon at the 162nd American Psychiatric Association Annual Meeting

...isms in the dopamine receptor 2 gene on iloperidone efficacy for the treatment of patients with schizophrenia. NR7-009 Common effect of antipsychotics on biosynthesis and regulation of fatty acids and cholesterol supports a role of lipid homeostasis in schizophrenia. NR1-092 Select...

New Insights into the Mechanism of Action of Antipsychotic Drugs

...ociety, of a manuscript entitled "Common effect of antipsychotics on the biosynthesis and regulation of fatty acids ...tion highlights the discovery of a major effect of antipsychotics that sheds new light on how these drugs work. Vand...researchers analyzed the mechanism of action of 18 antipsychotics at the molecular level and discovered that they re...

Orexigen(R) Therapeutics Announces Third Quarter 2008 Financial Results

...besity through 2023. The USPTO has also issued U.S. Patent No. 7,429,580 which broadly covers zonisamide in combination with various marketed atypical antipsychotics through 2025. Orexigen has licensed both patents on an exclusive basis from Duke University. The Company also made a number of important presentatio...

Lilly to Take Charge to Earnings Related to Pending Federal and State Investigations of Past Practices

... relative risk estimates are inconsistent, the association between atypical antipsychotics and increases in glucose levels appears to fall on a continuum and olanzapi...ontrol. Persons with risk factors for diabetes who are starting on atypical antipsychotics should undergo baseline and periodic fasting blood glucose testing. Patient...

Orexigen(R) Therapeutics Initiates First Clinical Trial of OREX-003 for the Mitigation of Antipsychotic-Associated Weight Gain

...besity through 2023. The USPTO has also issued U.S. Patent No. 7,429,580 which broadly covers zonisamide in combination with various marketed atypical antipsychotics including olanzapine, clozapine, risperidone, quetiapine, aripiprazole and ziprasidone through 2025. We believe that these patents complement each oth...

U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) as the First Medication for Add-On Treatment of Major Depressive Disorder (MDD)

...and diabetes mellitus-Hyperglycemia, in some cases associated with ketoacidosis, coma, or death, has been reported in patients treated with atypical antipsychotics including ABILIFY. Patients with diabetes should be monitored for worsening of glucose control; those with risk factors for diabetes should undergo ...
Antipsychotics in Biological Definition

Diabetes mellitus

...s , some chemotherapy agents (especially L-asparaginase), and some of the antipsychotics and mood stabilizers (especially phenothiazines and some atypical antipsychotics ). Diabetes is often detected when a person suffers a problem frequentl...
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