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Antipsychotic in Medical News

Mylan Receives FDA Approval for Additional Strengths of the Antipsychotic Haloperidol

PITTSBURGH, July 20 /PRNewswire-FirstCall/ -- Mylan Inc. (Nasdaq: MYL ) today announced that its subsidiary Mylan Pharmaceuticals Inc. has received approval from the U.S. Food and Drug Administration (FDA) for its supplemental Abbreviated New Drug Application (ANDA) for ...

FDA Panel OKs Antipsychotic Seroquel for Children

The drug, and others like it, have been linked to certain health risks, experts note,, WEDNESDAY, June 10 (HealthDay News) -- A U.S. Food and Drug Administration advisory panel on Wednesday voted "overwhelmingly" that Seroquel, a powerful antipsychotic drug, be approved to treat schiz...

Joint Statement on Atypical Antipsychotic Use in Children

WASHINGTON, June 8 /PRNewswire-USNewswire/ -- The below listed groups issued the following statement regarding the upcoming FDA Psychopharmacologic Drugs Advisory Committee Meeting on June 9-10: As advocates for people living with mental illnesses, we strongly urge the FDA to carefully consid...

New tool to improve patient understanding of long-acting injectable antipsychotic therapies (LAT) unveiled in April issue of Psychiatry 2009

Titusville, NJ, May 27, 2009 A new instrument for improving patient understanding and acceptance of long-acting injectable antipsychotic therapy (LAT) has been published in the April edition of Psychiatry 2009. 1 This novel, psychosocial approach encompasses G oal setting, A ction plan...

Combating weight gain caused by antipsychotic treatments

Philadelphia, PA, March 26, 2009 Antipsychotic drugs, such as olanzapine (Zyprexa), risperidone (Risperdal) and quetiapine (Seroquel), are commonly used to treat psychotic disorders like schizophrenia, but also bipolar disorder and even behavioral problems related to dementia. Unfortunately, th...

First generation antipsychotic drugs as effective as newer ones in some children

CHAPEL HILL Nearly every child who receives an antipsychotic medicine is first prescribed one of the second-generation, or atypical drugs, such as olanzapine and risperidone. However, there has never been evidence that these drugs are more effective than the older, first-generation medications. ...

Scientists ID Pathway That Makes Antipsychotic Drugs Work

Finding could aid drug manufacturers in development of new therapies TUESDAY, Aug. 26 (HealthDay News) -- New findings that antipsychotic drugs may not work as scientists have assumed could lead to changes in how the drugs are developed and prescribed, say Duke University Medical Cent...

Comparison of antipsychotic treatments in adolescents with schizophrenia

Philadelphia, PA, February 28, 2008 There is a wealth of scientific literature available on the treatment of adults diagnosed with schizophrenia. However, there is a paucity of data to guide the treatment of children and adolescents with schizophrenia. Although the U.S. Food and Drug Administra...

Weight gain induced by antipsychotic drugs can be avoided

Quebec City, January 16, 2008A research team from Universit Lavals Faculty of Medicine and Robert-Giffard Hospital has demonstrated that weight gain induced by the use of antipsychotic drugswhich in extreme cases can be as high as 30 kilos in only one monthcan be avoided through a specially design...

Some antipsychotic drugs may be missing their mark

COLUMBUS, Ohio Drugs that treat depression, schizophrenia and other psychotic conditions and that target a particular protein on brain cells might not be triggering the most appropriate response in those cells, new research suggests. The study by researchers at The Ohio State University Medical...

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Antipsychotic in Medical Technology

Forest Laboratories, Inc. and Gedeon Richter Plc Announce Positive Phase II Results with the Investigational Antipsychotic Cariprazine in Patients with Acute Mania Associated with Bipolar I Disorder

NEW YORK and BUDAPEST, Hungary, Sept. 30 /PRNewswire-FirstCall/ -- Forest Laboratories, Inc. (NYSE: FRX ) and Gedeon Richter Plc today announced preliminary top-line results from a phase II clinical trial of cariprazine (RGH-188), an investigational antipsychotic, in patients with acute mania...

AstraZeneca Submits sNDA for SEROQUEL XR(TM) for the Treatment of Generalized Anxiety Disorder - a First for the Atypical Antipsychotic Class of Medicines

WILMINGTON, Del., May 8 /PRNewswire-FirstCall/ -- AstraZeneca (NYSE: AZN) today announced the submission of a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for SEROQUEL XR(TM) (quetiapine fumarate) Extended-Release Tablets to seek approval for the trea...

Genetic Variation Associated with Treatment Response in a Clinical Study of a New Atypical Antipsychotic Fiaptatm (iloperidone)

ROCKVILLE, Md., Feb. 29 /PRNewswire-FirstCall/ -- A study reported in the journal Pharmacogenomics suggests that a genetic variation in the Ciliary Neurotrophic Factor gene (CNTF) may affect response to antipsychotic treatment. The study, conducted by Vanda Pharmaceuticals Inc., included patie...

New Data Show Early Non-Response to Antipsychotic Treatment May Be Strong Predictor of Subsequent Non-Response for People with Schizophrenia

Findings indicate early non-responders unlikely to subsequently respond, have substantially more treatment costs, and may benefit from earlier change in treatment strategy COLORADO SPRINGS, Colo., April 03, 2007 /PRNewswire-FirstCall/ -- New data presented at the 2007 International Congress on Sch...

Video: FDA Approves INVEGA(R) SUSTENNA(TM) for the Acute and Maintenance Treatment of Schizophrenia

...rst once-monthly, long-acting, injectable atypical antipsychotic approved in the U.S. for this use. Janssen((R)), D...t that includes continuous, long-term therapy with antipsychotic medications.(1) Unfortunately, 80 percent o...s that many patients treated with an oral atypical antipsychotic miss taking medication for about one-third of the ...

FDA Advisory Committee Votes in Favor of SAPHRIS(R) (asenapine) for Acute Bipolar I Disorder and Acute Schizophrenia

...e a number of medications available for patients, treatment success for any antipsychotic agent can be unpredictable because patients often respond differently to va...ipidemia) and glucose dysregulation, is an important consideration with any antipsychotic treatment. Patients often need to switch treatments in order for physician...

FDA Advisory Committee Votes in Favor of Zyprexa for Two Adolescent Indications

...ients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. I...nt should accompany drug therapy. As with all antipsychotic medications, a rare and potentially fatal conditio...e regular monitoring of weight. As with all antipsychotic treatment, prescribing should be consistent with t...

Study Demonstrating Lurasidone Is Effective in Patients With Schizophrenia Published in The Journal of Clinical Psychiatry

...tential psychotropic agent for the treatment of schizophrenia. Lurasidone has a unique chemical structure that differs from conventional and atypical antipsychotic agents. It possesses high affinities for dopamine D(2), serotonin 5-HT(7), 5-HT(2A), 5-HT(1A), and noradrenaline alpha(2C) receptors. Lurasidone exhi...

RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder

...atment (RLAT) is a long-acting injectable atypical antipsychotic therapy used for the treatment of schizophrenia an...ients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death compared t...ients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Analyses ...

ValueOptions(R) Supports New Hospital-Based Performance Measures to Help Patients Get the Best Treatment for Inpatient and Outpatient Services

...se Hours of seclusion use Patients discharged on multiple antipsychotic medications Patients discharged on multiple antipsychotic medications with appropriate justification Post discharge continuin...
Antipsychotic in Medical Dictionary

Diaphoresis

... Diaphoresis . Diaphragmatic hernia. Diarrhea associated with medications. Diastasis recti ... The withdrawal of heterocyclic antidepressants and antipsychotic agents can ... diarrhoea, rhinorrhoea, diaphoresis , myalgias, paraesthesias, anxiety, agitation, ... ...
Antipsychotic in Biological News

Genetic variant predicts antipsychotic response for schizophrenia patients by ethnicity

Philadelphia, PA, January 8, 2008 Schizophrenia is a developmental disorder with a large genetic component contributing to increased risk. Available antipsychotic medications treat some of the symptoms of schizophrenia, but are typically effective in only a subset of patients. Unfortunately, it...

Studies look at how genes affect antipsychotic drug response

Researchers at the University of Illinois at Chicago College of Pharmacy are attempting to discover how genes determine how well an antipsychotic medication works in adults and children and the side effects it will cause. Risperidone, a popular "atypical" antipsychotic medication, is used to trea...

FDA Warns About Antipsychotic Drugs and Elderly

The Food and Drug Administration (FDA) today issued a public health advisory to alert health care providers, patients, and patient caregivers to new safety information concerning an unapproved (i.e., "off-label") use of certain drugs called "atypical antipsychotic drugs." These drugs are approved f...

Flow of potassium into cells implicated in schizophrenia

...cardiac side effects associated with some existing antipsychotic medications. Scientists at the National Institutes...he chemical messenger dopamine, the main target of antipsychotic medications used to treat schizophrenia. One ty...hmias and even sudden death a rare risk of taking antipsychotic medications, many of which interact with KCNH2. So...

Researchers discover link between schizophrenia and diabetes

...s believe that developmental abnormalities they don't yet know about also increase diabetes risk. One recent study based on data from the Clinical antipsychotic Trials of Intervention Effectiveness Schizophrenia Trial showed the prevalence rate of metabolic syndrome, a group of risk factors that include abdom...

Pitt research identifies new target in brain for treating schizophrenia

...rain region that responds to more than one type of antipsychotic drug. The findings illustrate for the first time t... could be a promising target for developing future antipsychotic drugseven those that have very different mechanism...n activity was then normalized both by established antipsychotic medications that regulate only dopamine and by exp...

NARSAD announces 2008 Prizes for Outstanding Achievement in Research on Mental Health Disorders

...on (FDA) and wide dissemination to patients. These have included the anticonvulsants valproate (Depakote) and lamotrigine (Lamictal), and the atypical antipsychotic quetiapine (Seroquel). These agents have vastly enlarged our treatment armamentarium and provided new options for patients with bipolar disorder, maki...

Brain-nourishing molecule may predict schizophrenia relapse

...void devastating relapse. "Our aim is to bring BDNF levels back to normal." Dr. Pillai and colleagues already have shown in their animal studies that antipsychotic drugs do better boosting brain BDNF levels when administered along with any of the above drugs. He adds that both cysteamine and erythropoietin have ...

Risks and benefits of antipsychotics in children and adolescents

...rticularly with the introduction of new-generation antipsychotic medications, have created a lot of expectations in...label use (=non-approved use). Clinical trials of antipsychotic drugs traditionally focus on acute clinical effica... intervention with an effective and well-tolerated antipsychotic may provide benefits that may modify the actual co...

Like eavesdropping at a party

...ge of calcium is critical for understanding how cells communicate, says Yue, and also important for understanding neural diseases. For instance, early antipsychotic drugs may work by blocking calmodulin action. "Now that we are learning how these drugs actually work," Yue says, "we can contribute our new understan...
Antipsychotic in Biological Technology

New Insights into the Mechanism of Action of Antipsychotic Drugs

ROCKVILLE, Md., March 10 /PRNewswire-FirstCall/ -- Vanda Pharmaceuticals Inc. (Nasdaq: VNDA ) reports the publication in Schizophrenia Research , the official journal of the Schizophrenia International Research Society, of a manuscript entitled "Common effect of antipsychotics on the biosynthes...

Femtogram Sensitivity of the Antipsychotic Drugs Raclopride and Ritanserin Using a Varian 1200L LC/MS/MS

J. Beck and C. Schmidt Varian, Inc. Introduction Ritanserin (Tisterton) is a serotonin-2 antagonist drug shown to be effective in the treatment of anxiety and depression 1 while Raclopride acts as a dopamine D2 receptor antagonist. 2 These two compound...

Genomas and Institute of Living Among Organizers of Pharmacogenetics Symposium at 2009 Annual Meeting of the American Psychiatric Association

...major depressive disorder (MDD). Data were obtained from the DNA of 150 psychiatric in-patients being treated for MDD with antidepressant and atypical antipsychotic medications at the Institute of Living. "These genetic variations may contribute to a reduction in efficacy or an increase in side effects of med...

Vanda Pharmaceuticals to Present Data on Fanapt(TM) and Tasimelteon at the 162nd American Psychiatric Association Annual Meeting

...ia. NR1-092 Selective estrogen receptor modulators share the antipsychotic gene expression profile, suggesting their potential in the treatment of...www.vandapharma.com . About Fanapt(TM) Fanapt(TM) is an atypical antipsychotic agent indicated for the acute treatment of schizophrenia in adults. In cho...

Psylin Neurosciences Commences Development of Compound for Depression

...PSN0041 will be the first compound in Psylin's pipeline to enter into clinical development. Other compounds are being investigated for development as antipsychotic and mood stabilizing therapies. Amylin's proprietary peptide library known as PHORMOL encompasses an extensive panel of potentially valuable biol...

Intra-Cellular Therapies Reports Positive Final Results of a Phase II Clinical Trial with ITI-007 in Patients with Sleep Maintenance Insomnia

... addition, the wide separation of affinity at 5HT2A and D2 receptors may allow for administration of the appropriate amount of dopamine modulation for antipsychotic maintenance therapy and the treatment of bipolar disorders. ITI-007 has a low propensity to interact with receptors that mediate deleterious car...

Schering-Plough Submits Response to FDA for SAPHRIS(TM) (asenapine) in the Acute Treatment of Both Schizophrenia and Bipolar I Disorder

...ugh Research Institute. Schering-Plough acquired asenapine in November 2007 through its acquisition of Organon BioSciences, which developed the antipsychotic agent. The New Drug Application (NDA) for asenapine includes data from a clinical trial program involving more than 3,000 patients in schizophrenia a...

FDA Issues Complete Response Letter for RISPERDAL(R) CONSTA(R) for the Adjunctive Maintenance Treatment of Bipolar Disorder

...zophrenia. IMPORTANT SAFETY INFORMATION FOR RISPERDAL(R) CONSTA(R) Elderly Patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared to placebo. RISPERDAL(R) CONSTA(R) (risperidone) is not approved for the treatment of patients with d...

Phase 3 Data Demonstrate Efficacy and Tolerability of Paliperidone Palmitate, an Investigational Long-Acting Therapy for the Treatment of Schizophrenia

...aliperidone palmitate, an investigational LAT, is a formulation of the oral antipsychotic paliperidone ER, used for the acute and maintenance treatment of schizophre... Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared to placebo. Paliperidone i...

Lilly to Take Charge to Earnings Related to Pending Federal and State Investigations of Past Practices

...t U.S. marketing and promotional practices for its antipsychotic medication Zyprexa(R) (olanzapine). As a result, t...h dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared w...eceive regular monitoring of weight. As with all antipsychotic medications, a rare and potentially fatal conditio...
Antipsychotic in Biological Definition

Drug

...ressants Fluoxetine Paroxetine Tranquilizers Typical antipsychotic tranquilizers Thorazine Atypical antipsychotic tranquilizers Sedatives Valium Regulations Us...
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