Mylan Receives FDA Approval for Additional Strengths of the Antipsychotic Haloperidol
PITTSBURGH, July 20 /PRNewswire-FirstCall/ -- Mylan Inc. (Nasdaq: MYL ) today announced that its subsidiary Mylan Pharmaceuticals Inc. has received approval from the U.S. Food and Drug Administration (FDA) for its supplemental Abbreviated New Drug Application (ANDA) for ...
FDA Panel OKs Antipsychotic Seroquel for Children
The drug, and others like it, have been linked to certain health risks, experts note,,
WEDNESDAY, June 10 (HealthDay News) -- A U.S. Food and Drug Administration advisory panel on Wednesday voted "overwhelmingly" that Seroquel, a powerful antipsychotic
drug, be approved to treat schiz...
Joint Statement on Atypical Antipsychotic Use in Children
WASHINGTON, June 8 /PRNewswire-USNewswire/ -- The below listed groups issued the following statement regarding the upcoming FDA Psychopharmacologic Drugs Advisory Committee Meeting on June 9-10:
As advocates for people living with mental illnesses, we strongly urge the FDA to carefully consid...
New tool to improve patient understanding of long-acting injectable antipsychotic therapies (LAT) unveiled in April issue of Psychiatry 2009
Titusville, NJ, May 27, 2009 A new instrument for improving patient understanding and acceptance of long-acting injectable antipsychotic
therapy (LAT) has been published in the April edition of Psychiatry 2009. 1 This novel, psychosocial approach encompasses G oal setting, A ction plan...
Combating weight gain caused by antipsychotic treatments
Philadelphia, PA, March 26, 2009 Antipsychotic
drugs, such as olanzapine (Zyprexa), risperidone (Risperdal) and quetiapine (Seroquel), are commonly used to treat psychotic disorders like schizophrenia, but also bipolar disorder and even behavioral problems related to dementia. Unfortunately, th...
First generation antipsychotic drugs as effective as newer ones in some children
CHAPEL HILL Nearly every child who receives an antipsychotic
medicine is first prescribed one of the second-generation, or atypical drugs, such as olanzapine and risperidone. However, there has never been evidence that these drugs are more effective than the older, first-generation medications.
Scientists ID Pathway That Makes Antipsychotic Drugs Work
Finding could aid drug manufacturers in development of new therapies
TUESDAY, Aug. 26 (HealthDay News) -- New findings that antipsychotic
drugs may not work as scientists have assumed could lead to changes in how the drugs are developed and prescribed, say Duke University Medical Cent...
Comparison of antipsychotic treatments in adolescents with schizophrenia
Philadelphia, PA, February 28, 2008 There is a wealth of scientific literature available on the treatment of adults diagnosed with schizophrenia. However, there is a paucity of data to guide the treatment of children and adolescents with schizophrenia. Although the U.S. Food and Drug Administra...
Weight gain induced by antipsychotic drugs can be avoided
Quebec City, January 16, 2008A research team from Universit Lavals Faculty of Medicine and Robert-Giffard Hospital has demonstrated that weight gain induced by the use of antipsychotic
drugswhich in extreme cases can be as high as 30 kilos in only one monthcan be avoided through a specially design...
Some antipsychotic drugs may be missing their mark
COLUMBUS, Ohio Drugs that treat depression, schizophrenia and other psychotic conditions and that target a particular protein on brain cells might not be triggering the most appropriate response in those cells, new research suggests.
The study by researchers at The Ohio State University Medical...
Antipsychotic in Medical Technology
Forest Laboratories, Inc. and Gedeon Richter Plc Announce Positive Phase II Results with the Investigational Antipsychotic Cariprazine in Patients with Acute Mania Associated with Bipolar I Disorder
NEW YORK and BUDAPEST, Hungary, Sept. 30 /PRNewswire-FirstCall/ --
Forest Laboratories, Inc. (NYSE: FRX ) and Gedeon Richter Plc today
announced preliminary top-line results from a phase II clinical trial of
cariprazine (RGH-188), an investigational antipsychotic, in patients with
AstraZeneca Submits sNDA for SEROQUEL XR(TM) for the Treatment of Generalized Anxiety Disorder - a First for the Atypical Antipsychotic Class of Medicines
WILMINGTON, Del., May 8 /PRNewswire-FirstCall/ -- AstraZeneca (NYSE:
AZN) today announced the submission of a supplemental New Drug Application
(sNDA) to the U.S. Food and Drug Administration (FDA) for SEROQUEL XR(TM)
(quetiapine fumarate) Extended-Release Tablets to seek approval for the
Genetic Variation Associated with Treatment Response in a Clinical Study of a New Atypical Antipsychotic Fiaptatm (iloperidone)
ROCKVILLE, Md., Feb. 29 /PRNewswire-FirstCall/ -- A study reported in
the journal Pharmacogenomics suggests that a genetic variation in the
Ciliary Neurotrophic Factor gene (CNTF) may affect response to
antipsychotic treatment. The study, conducted by Vanda Pharmaceuticals
Inc., included patie...
New Data Show Early Non-Response to Antipsychotic Treatment May Be
Strong Predictor of Subsequent Non-Response for People with
Findings indicate early non-responders unlikely to subsequently
respond, have substantially more treatment costs, and may benefit
from earlier change in treatment strategy
COLORADO SPRINGS, Colo., April 03, 2007 /PRNewswire-FirstCall/
-- New data presented at the 2007 International Congress on
Video: FDA Approves INVEGA(R) SUSTENNA(TM) for the Acute and Maintenance Treatment of Schizophrenia
...rst once-monthly, long-acting, injectable atypical antipsychotic
approved in the U.S. for this use. Janssen((R)), D...t that includes continuous, long-term therapy with antipsychotic
Unfortunately, 80 percent o...s that many patients treated with an oral atypical antipsychotic
miss taking medication for about one-third of the ...
FDA Advisory Committee Votes in Favor of SAPHRIS(R) (asenapine) for Acute Bipolar I Disorder and Acute Schizophrenia
...e a number of medications available for patients, treatment success for any antipsychotic
agent can be unpredictable because patients often respond differently to va...ipidemia) and glucose dysregulation, is an important consideration with any antipsychotic
treatment. Patients often need to switch treatments in order for physician...
FDA Advisory Committee Votes in Favor of Zyprexa for Two Adolescent Indications
...ients with dementia-related psychosis treated with antipsychotic
drugs are at an increased risk of death.
I...nt should accompany drug therapy.
As with all antipsychotic
medications, a rare and potentially fatal conditio...e regular monitoring of weight.
As with all antipsychotic
treatment, prescribing should be consistent with t...
Study Demonstrating Lurasidone Is Effective in Patients With Schizophrenia Published in The Journal of Clinical Psychiatry
...tential psychotropic agent for the treatment of schizophrenia. Lurasidone has a unique chemical structure that differs from conventional and atypical antipsychotic
agents. It possesses high affinities for dopamine D(2), serotonin 5-HT(7), 5-HT(2A), 5-HT(1A), and noradrenaline alpha(2C) receptors. Lurasidone exhi...
RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder
...atment (RLAT) is a long-acting injectable atypical antipsychotic
therapy used for the treatment of schizophrenia an...ients with dementia-related psychosis treated with antipsychotic
drugs are at an increased risk of death compared t...ients with dementia-related psychosis treated with antipsychotic
drugs are at an increased risk of death. Analyses ...
ValueOptions(R) Supports New Hospital-Based Performance Measures to Help Patients Get the Best Treatment for Inpatient and Outpatient Services
Hours of seclusion use
Patients discharged on multiple antipsychotic
Patients discharged on multiple antipsychotic
medications with appropriate justification
Post discharge continuin...
Antipsychotic in Medical Dictionary
... Diaphoresis . Diaphragmatic hernia. Diarrhea associated with medications. Diastasis recti ... The withdrawal of heterocyclic antidepressants and antipsychotic
agents can ... diarrhoea, rhinorrhoea, diaphoresis , myalgias, paraesthesias, anxiety, agitation, ... ...
Antipsychotic in Biological News
Genetic variant predicts antipsychotic response for schizophrenia patients by ethnicity
Philadelphia, PA, January 8, 2008 Schizophrenia is a developmental disorder with a large genetic component contributing to increased risk. Available antipsychotic
medications treat some of the symptoms of schizophrenia, but are typically effective in only a subset of patients. Unfortunately, it...
Studies look at how genes affect antipsychotic drug response
Researchers at the University of Illinois at Chicago College of Pharmacy are attempting to discover how genes determine how well an antipsychotic
medication works in adults and children and the side effects it will cause.
Risperidone, a popular "atypical" antipsychotic
medication, is used to trea...
FDA Warns About Antipsychotic Drugs and Elderly
The Food and Drug Administration (FDA) today issued a public health advisory to alert health care providers, patients, and patient caregivers to new safety information concerning an unapproved (i.e., "off-label") use of certain drugs called "atypical antipsychotic
drugs." These drugs are approved f...
Flow of potassium into cells implicated in schizophrenia
...cardiac side effects associated with some existing antipsychotic
medications. Scientists at the National Institutes...he chemical messenger dopamine, the main target of antipsychotic
medications used to treat schizophrenia.
One ty...hmias and even sudden death a rare risk of taking antipsychotic
medications, many of which interact with KCNH2. So...
Researchers discover link between schizophrenia and diabetes
...s believe that developmental abnormalities they don't yet know about also increase diabetes risk.
One recent study based on data from the Clinical antipsychotic
Trials of Intervention Effectiveness Schizophrenia Trial showed the prevalence rate of metabolic syndrome, a group of risk factors that include abdom...
Pitt research identifies new target in brain for treating schizophrenia
...rain region that responds to more than one type of antipsychotic
drug. The findings illustrate for the first time t... could be a promising target for developing future antipsychotic
drugseven those that have very different mechanism...n activity was then normalized both by established antipsychotic
medications that regulate only dopamine and by exp...
NARSAD announces 2008 Prizes for Outstanding Achievement in Research on Mental Health Disorders
...on (FDA) and wide dissemination to patients. These have included the anticonvulsants valproate (Depakote) and lamotrigine (Lamictal), and the atypical antipsychotic
quetiapine (Seroquel). These agents have vastly enlarged our treatment armamentarium and provided new options for patients with bipolar disorder, maki...
Brain-nourishing molecule may predict schizophrenia relapse
...void devastating relapse. "Our aim is to bring BDNF levels back to normal." Dr. Pillai and colleagues already have shown in their animal studies that antipsychotic
drugs do better boosting brain BDNF levels when administered along with any of the above drugs. He adds that both cysteamine and erythropoietin have ...
Risks and benefits of antipsychotics in children and adolescents
...rticularly with the introduction of new-generation antipsychotic
medications, have created a lot of expectations in...label use (=non-approved use).
Clinical trials of antipsychotic
drugs traditionally focus on acute clinical effica... intervention with an effective and well-tolerated antipsychotic
may provide benefits that may modify the actual co...
Like eavesdropping at a party
...ge of calcium is critical for understanding how cells communicate, says Yue, and also important for understanding neural diseases. For instance, early antipsychotic
drugs may work by blocking calmodulin action. "Now that we are learning how these drugs actually work," Yue says, "we can contribute our new understan...
Antipsychotic in Biological Technology
New Insights into the Mechanism of Action of Antipsychotic Drugs
ROCKVILLE, Md., March 10 /PRNewswire-FirstCall/ -- Vanda Pharmaceuticals Inc. (Nasdaq: VNDA ) reports the publication in Schizophrenia Research , the official journal of the Schizophrenia International Research Society, of a manuscript entitled "Common effect of antipsychotics on the biosynthes...
Femtogram Sensitivity of the Antipsychotic Drugs Raclopride and Ritanserin Using a Varian 1200L LC/MS/MS
J. Beck and C. Schmidt
Ritanserin (Tisterton) is a serotonin-2 antagonist drug shown to be effective in the treatment of anxiety and depression 1 while Raclopride acts as a dopamine D2 receptor antagonist. 2 These two compound...
Genomas and Institute of Living Among Organizers of Pharmacogenetics Symposium at 2009 Annual Meeting of the American Psychiatric Association
...major depressive disorder (MDD). Data were obtained from the DNA of 150 psychiatric in-patients being treated for MDD with antidepressant and atypical antipsychotic
medications at the Institute of Living.
"These genetic variations may contribute to a reduction in efficacy or an increase in side effects of med...
Vanda Pharmaceuticals to Present Data on Fanapt(TM) and Tasimelteon at the 162nd American Psychiatric Association Annual Meeting
NR1-092 Selective estrogen receptor modulators share the
gene expression profile, suggesting their potential in the
treatment of...www.vandapharma.com .
Fanapt(TM) is an atypical antipsychotic
agent indicated for the acute treatment of schizophrenia in adults. In cho...
Psylin Neurosciences Commences Development of Compound for Depression
...PSN0041 will be the first compound in Psylin's pipeline to enter into clinical development. Other compounds are being investigated for development as antipsychotic
and mood stabilizing therapies.
Amylin's proprietary peptide library known as PHORMOL encompasses an extensive panel of potentially valuable biol...
Intra-Cellular Therapies Reports Positive Final Results of a Phase II Clinical Trial with ITI-007 in Patients with Sleep Maintenance Insomnia
... addition, the wide separation of affinity at 5HT2A and D2 receptors may allow for administration of the appropriate amount of dopamine modulation for antipsychotic
maintenance therapy and the treatment of bipolar disorders.
ITI-007 has a low propensity to interact with receptors that mediate deleterious car...
Schering-Plough Submits Response to FDA for SAPHRIS(TM) (asenapine) in the Acute Treatment of Both Schizophrenia and Bipolar I Disorder
...ugh Research Institute.
Schering-Plough acquired asenapine in November 2007 through its acquisition of Organon BioSciences, which developed the antipsychotic
agent. The New Drug Application (NDA) for asenapine includes data from a clinical trial program involving more than 3,000 patients in schizophrenia a...
FDA Issues Complete Response Letter for RISPERDAL(R) CONSTA(R) for the Adjunctive Maintenance Treatment of Bipolar Disorder
IMPORTANT SAFETY INFORMATION FOR RISPERDAL(R) CONSTA(R)
Elderly Patients with dementia-related psychosis treated with atypical antipsychotic
drugs are at an increased risk of death compared to placebo. RISPERDAL(R) CONSTA(R) (risperidone) is not approved for the treatment of patients with d...
Phase 3 Data Demonstrate Efficacy and Tolerability of Paliperidone Palmitate, an Investigational Long-Acting Therapy for the Treatment of Schizophrenia
...aliperidone palmitate, an investigational LAT, is a formulation of the oral antipsychotic
paliperidone ER, used for the acute and maintenance treatment of schizophre...
Elderly patients with dementia-related psychosis treated with atypical antipsychotic
drugs are at an increased risk of death compared to placebo. Paliperidone i...
Lilly to Take Charge to Earnings Related to Pending Federal and State Investigations of Past Practices
...t U.S. marketing and
promotional practices for its antipsychotic
(olanzapine). As a result, t...h dementia-related
psychosis treated with atypical antipsychotic
drugs are at an increased
risk of death compared w...eceive regular
monitoring of weight.
As with all antipsychotic
medications, a rare and potentially fatal
Antipsychotic in Biological Definition